메뉴 건너뛰기




Volumn 72, Issue 5, 2008, Pages 1544-1550

mRNA Expression of Platelet-Derived Growth Factor Receptor-β and C-KIT: Correlation With Pathologic Response to Cetuximab-Based Chemoradiotherapy in Patients With Rectal Cancer

Author keywords

C kit; Chemoradiotherapy; PDGFR ; Platelet derived growth factor receptor ; Quantitative real time polymerase chain reaction; quantitative RT PCR; Rectal cancer

Indexed keywords

ABS RESINS; BIOACTIVITY; BIOPSY; BLOOD SUBSTITUTES; PEPTIDES; POLYMERIZATION; PUMPS; RATE CONSTANTS; REGRESSION ANALYSIS; TUMORS;

EID: 56349085600     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2008.08.013     Document Type: Article
Times cited : (14)

References (27)
  • 1
    • 6044226542 scopus 로고    scopus 로고
    • Preoperative versus postoperative chemoradiotherapy for rectal cancer
    • Sauer R., Becker H., Hohenberger W., et al. Preoperative versus postoperative chemoradiotherapy for rectal cancer. N Engl J Med 351 (2004) 1731-1740
    • (2004) N Engl J Med , vol.351 , pp. 1731-1740
    • Sauer, R.1    Becker, H.2    Hohenberger, W.3
  • 2
    • 39749153032 scopus 로고    scopus 로고
    • Phase I-II trial of cetuximab, capecitabine, oxaliplatin, and radiotherapy as preoperative treatment in rectal cancer
    • Rodel C., Arnold D., Hipp M., et al. Phase I-II trial of cetuximab, capecitabine, oxaliplatin, and radiotherapy as preoperative treatment in rectal cancer. Int J Radiat Oncol Biol Phys 70 (2008) 1081-1086
    • (2008) Int J Radiat Oncol Biol Phys , vol.70 , pp. 1081-1086
    • Rodel, C.1    Arnold, D.2    Hipp, M.3
  • 3
    • 33644842988 scopus 로고    scopus 로고
    • Prognostic significance of tumor regression after preoperative chemoradiotherapy for rectal cancer
    • Rodel C., Martus P., Papadoupolos T., et al. Prognostic significance of tumor regression after preoperative chemoradiotherapy for rectal cancer. J Clin Oncol 23 (2005) 8688-8696
    • (2005) J Clin Oncol , vol.23 , pp. 8688-8696
    • Rodel, C.1    Martus, P.2    Papadoupolos, T.3
  • 4
    • 45049088412 scopus 로고    scopus 로고
    • Prognostic value of pathologic complete response after neoadjuvant therapy in locally advanced rectal cancer: long-term analysis of 566 ypCR patients
    • Capirci C., Valentini V., Cionini L., et al. Prognostic value of pathologic complete response after neoadjuvant therapy in locally advanced rectal cancer: long-term analysis of 566 ypCR patients. Int J Radiat Oncol Biol Phys 72 (2008) 99-107
    • (2008) Int J Radiat Oncol Biol Phys , vol.72 , pp. 99-107
    • Capirci, C.1    Valentini, V.2    Cionini, L.3
  • 5
    • 33750360895 scopus 로고    scopus 로고
    • Combined vascular endothelial growth factor-targeted therapy and radiotherapy for rectal cancer: Theory and clinical practice
    • Willett C.G., Kozin S.V., Duda D.G., et al. Combined vascular endothelial growth factor-targeted therapy and radiotherapy for rectal cancer: Theory and clinical practice. Semin Oncol 33 5 Suppl. 10 (2006) S35-S40
    • (2006) Semin Oncol , vol.33 , Issue.5 SUPPL. 10
    • Willett, C.G.1    Kozin, S.V.2    Duda, D.G.3
  • 6
    • 33751169352 scopus 로고    scopus 로고
    • Phase I trial of cetuximab in combination with capecitabine, weekly irinotecan, and radiotherapy as neoadjuvant therapy for rectal cancer
    • Hofheinz R.D., Horisberger K., Woernle C., et al. Phase I trial of cetuximab in combination with capecitabine, weekly irinotecan, and radiotherapy as neoadjuvant therapy for rectal cancer. Int J Radiat Oncol Biol Phys 66 (2006) 1384-1390
    • (2006) Int J Radiat Oncol Biol Phys , vol.66 , pp. 1384-1390
    • Hofheinz, R.D.1    Horisberger, K.2    Woernle, C.3
  • 7
    • 0034989658 scopus 로고    scopus 로고
    • Developmental roles of platelet-derived growth factors
    • Betsholtz C., Karlsson L., and Lindahl P. Developmental roles of platelet-derived growth factors. Bioessays 23 (2001) 494-507
    • (2001) Bioessays , vol.23 , pp. 494-507
    • Betsholtz, C.1    Karlsson, L.2    Lindahl, P.3
  • 8
    • 0026551550 scopus 로고
    • Genomic organization of the human c-kit gene: Evolution of the receptor tyrosine kinase subclass III
    • Andre C., Martin E., Cornu F., et al. Genomic organization of the human c-kit gene: Evolution of the receptor tyrosine kinase subclass III. Oncogene 7 (1992) 685-691
    • (1992) Oncogene , vol.7 , pp. 685-691
    • Andre, C.1    Martin, E.2    Cornu, F.3
  • 9
    • 7444269880 scopus 로고    scopus 로고
    • Expression of the proto-oncogene c-KIT in normal and tumor tissues from colorectal carcinoma patients
    • Sammarco I., Capurso G., Coppola L., et al. Expression of the proto-oncogene c-KIT in normal and tumor tissues from colorectal carcinoma patients. Int J Colorectal Dis 19 (2004) 545-553
    • (2004) Int J Colorectal Dis , vol.19 , pp. 545-553
    • Sammarco, I.1    Capurso, G.2    Coppola, L.3
  • 10
    • 34250814096 scopus 로고    scopus 로고
    • KIT/stem cell factor expression in premalignant and malignant lesions of the colon mucosa in relationship to disease progression and outcomes
    • Bellone G., Smirne C., Carbone A., et al. KIT/stem cell factor expression in premalignant and malignant lesions of the colon mucosa in relationship to disease progression and outcomes. Int J Oncol 29 (2006) 851-859
    • (2006) Int J Oncol , vol.29 , pp. 851-859
    • Bellone, G.1    Smirne, C.2    Carbone, A.3
  • 11
    • 26944437515 scopus 로고    scopus 로고
    • PDGFRbeta+ perivascular progenitor cells in tumours regulate pericyte differentiation and vascular survival
    • Song S., Ewald A.J., Stallcup W., et al. PDGFRbeta+ perivascular progenitor cells in tumours regulate pericyte differentiation and vascular survival. Nat Cell Biol 7 (2005) 870-879
    • (2005) Nat Cell Biol , vol.7 , pp. 870-879
    • Song, S.1    Ewald, A.J.2    Stallcup, W.3
  • 12
    • 33749441325 scopus 로고    scopus 로고
    • Rapid vascular regrowth in tumors after reversal of VEGF inhibition
    • Mancuso M.R., Davis R., Norberg S.M., et al. Rapid vascular regrowth in tumors after reversal of VEGF inhibition. J Clin Invest 116 (2006) 2610-2621
    • (2006) J Clin Invest , vol.116 , pp. 2610-2621
    • Mancuso, M.R.1    Davis, R.2    Norberg, S.M.3
  • 13
    • 34547643983 scopus 로고    scopus 로고
    • Targeting the expression of platelet-derived growth factor receptor by reactive stroma inhibits growth and metastasis of human colon carcinoma
    • Kitadai Y., Sasaki T., Kuwai T., et al. Targeting the expression of platelet-derived growth factor receptor by reactive stroma inhibits growth and metastasis of human colon carcinoma. Am J Pathol 169 (2006) 2054-2065
    • (2006) Am J Pathol , vol.169 , pp. 2054-2065
    • Kitadai, Y.1    Sasaki, T.2    Kuwai, T.3
  • 14
    • 13444257366 scopus 로고    scopus 로고
    • Antiangiogenic and antitumor activity of a selective PDGFR tyrosine kinase inhibitor, CP-673,451
    • Roberts W.G., Whalen P.M., Soderstrom E., et al. Antiangiogenic and antitumor activity of a selective PDGFR tyrosine kinase inhibitor, CP-673,451. Cancer Res 65 (2005) 957-966
    • (2005) Cancer Res , vol.65 , pp. 957-966
    • Roberts, W.G.1    Whalen, P.M.2    Soderstrom, E.3
  • 15
    • 20044396551 scopus 로고    scopus 로고
    • Blockade of platelet-derived growth factor receptor-beta by CDP860, a humanized, PEGylated di-Fab', leads to fluid accumulation and is associated with increased tumor vascularized volume
    • Jayson G.C., Parker G.J.M., Mullamitha S., et al. Blockade of platelet-derived growth factor receptor-beta by CDP860, a humanized, PEGylated di-Fab', leads to fluid accumulation and is associated with increased tumor vascularized volume. J Clin Oncol 23 (2005) 973-981
    • (2005) J Clin Oncol , vol.23 , pp. 973-981
    • Jayson, G.C.1    Parker, G.J.M.2    Mullamitha, S.3
  • 16
    • 0032875460 scopus 로고    scopus 로고
    • Mechanism of action and in vivo role of platelet-derived growth factor
    • Heldin C.-H., and Westermark B. Mechanism of action and in vivo role of platelet-derived growth factor. Physiol Rev 79 (1999) 1283-1316
    • (1999) Physiol Rev , vol.79 , pp. 1283-1316
    • Heldin, C.-H.1    Westermark, B.2
  • 18
    • 0036790060 scopus 로고    scopus 로고
    • Inhibition of PDGF receptor signaling in tumor stroma enhances antitumor effect of chemotherapy
    • Pietras K., Rubin K., Sjoblom T., et al. Inhibition of PDGF receptor signaling in tumor stroma enhances antitumor effect of chemotherapy. Cancer Res 62 (2002) 5476-5484
    • (2002) Cancer Res , vol.62 , pp. 5476-5484
    • Pietras, K.1    Rubin, K.2    Sjoblom, T.3
  • 19
    • 38349081290 scopus 로고    scopus 로고
    • Harmonization of BCR-ABL mRNA quantification using a uniform multifunctional control plasmid in 37 international laboratories
    • Muller M.C., Erben P., Saglio G., et al. Harmonization of BCR-ABL mRNA quantification using a uniform multifunctional control plasmid in 37 international laboratories. Leukemia 22 (2008) 96-102
    • (2008) Leukemia , vol.22 , pp. 96-102
    • Muller, M.C.1    Erben, P.2    Saglio, G.3
  • 20
    • 25444463573 scopus 로고    scopus 로고
    • Endothelial/pericyte interactions
    • Armulik A., Abramsson A., and Betsholtz C. Endothelial/pericyte interactions. Circ Res 97 (2005) 512-523
    • (2005) Circ Res , vol.97 , pp. 512-523
    • Armulik, A.1    Abramsson, A.2    Betsholtz, C.3
  • 21
    • 0038476608 scopus 로고    scopus 로고
    • Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors
    • Bergers G., Song S., Meyer-Morse N., et al. Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors. J Clin Invest 111 (2003) 1287-1295
    • (2003) J Clin Invest , vol.111 , pp. 1287-1295
    • Bergers, G.1    Song, S.2    Meyer-Morse, N.3
  • 22
    • 34247848503 scopus 로고    scopus 로고
    • The role of PDGF in radiation oncology
    • Li M., Jendrossek V., and Belka C. The role of PDGF in radiation oncology. Radiat Oncol 2 (2007) 5
    • (2007) Radiat Oncol , vol.2 , pp. 5
    • Li, M.1    Jendrossek, V.2    Belka, C.3
  • 23
    • 34047179551 scopus 로고    scopus 로고
    • Phase I/II study of preoperative cetuximab, capecitabine, and external beam radiotherapy in patients with rectal cancer
    • Machiels J.P., Sempoux C., Scalliet P., et al. Phase I/II study of preoperative cetuximab, capecitabine, and external beam radiotherapy in patients with rectal cancer. Ann Oncol 18 (2007) 738-744
    • (2007) Ann Oncol , vol.18 , pp. 738-744
    • Machiels, J.P.1    Sempoux, C.2    Scalliet, P.3
  • 24
    • 24944465683 scopus 로고    scopus 로고
    • Preoperative concurrent radiotherapy with capecitabine before total mesorectal excision in locally advanced rectal cancer
    • Kim J.C., Kim T.W., Kim J.H., et al. Preoperative concurrent radiotherapy with capecitabine before total mesorectal excision in locally advanced rectal cancer. Int J Radiat Oncol Biol Phys 63 (2005) 346-353
    • (2005) Int J Radiat Oncol Biol Phys , vol.63 , pp. 346-353
    • Kim, J.C.1    Kim, T.W.2    Kim, J.H.3
  • 25
    • 34247180454 scopus 로고    scopus 로고
    • Multicenter phase II trial of chemoradiation with oxaliplatin for rectal cancer
    • Rodel C., Liersch T., Hermann R.M., et al. Multicenter phase II trial of chemoradiation with oxaliplatin for rectal cancer. J Clin Oncol 25 (2007) 110-117
    • (2007) J Clin Oncol , vol.25 , pp. 110-117
    • Rodel, C.1    Liersch, T.2    Hermann, R.M.3
  • 26
    • 33947425624 scopus 로고    scopus 로고
    • A phase II study of capecitabine and irinotecan in combination with concurrent pelvic radiotherapy (CapIri-RT) as neoadjuvant treatment of locally advanced rectal cancer
    • Willeke F., Horisberger K., Kraus-Tiefenbacher U., et al. A phase II study of capecitabine and irinotecan in combination with concurrent pelvic radiotherapy (CapIri-RT) as neoadjuvant treatment of locally advanced rectal cancer. Br J Cancer 96 (2007) 912-917
    • (2007) Br J Cancer , vol.96 , pp. 912-917
    • Willeke, F.1    Horisberger, K.2    Kraus-Tiefenbacher, U.3
  • 27
    • 33750209783 scopus 로고    scopus 로고
    • Treatment with imatinib in NSCLC is associated with decrease of phosphorylated PDGFR-beta and VEGF expression, decrease in interstitial fluid pressure and improvement of oxygenation
    • Vlahovic G., Rabbani Z.N., Herndon II J.E., et al. Treatment with imatinib in NSCLC is associated with decrease of phosphorylated PDGFR-beta and VEGF expression, decrease in interstitial fluid pressure and improvement of oxygenation. Br J Cancer 95 (2006) 1013-1019
    • (2006) Br J Cancer , vol.95 , pp. 1013-1019
    • Vlahovic, G.1    Rabbani, Z.N.2    Herndon II, J.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.