The role of different glutamate receptors in the mediation of glutamate-evoked excitation of red nucleus neurons after simulated microgravity in rat

Neuroscience Letters

Volumn 448, Issue 3, 2008, Pages 255-259

  Yang, Jian Chang ^a,b   Fan, Xiao Li ^a   Song, Xin Ai ^a   Li, Qiang ^a  

^a MEDICAL SCHOOL OF XI AN JIAOTONG UNIVERSITY   (China)

^b Xi an Physical Education University   (China)

Author keywords

Glutamate; mGluR; NMDA receptor; Non NMDA receptor; Red nucleus; Simulated microgravity

Indexed keywords

6,7 DINITRO 2,3 QUINOXALINEDIONE; ALPHA METHYL 4 CARBOXYPHENYLGLYCINE; DIZOCILPINE; GLUTAMATE RECEPTOR; GLUTAMIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG ANTAGONISM; DRUG MECHANISM; FEMALE; MICROGRAVITY; MICROINJECTION; NERVE CELL; NERVE EXCITABILITY; NERVE POTENTIAL; NONHUMAN; PRIORITY JOURNAL; RAT; RED NUCLEUS;

ANIMALS; DIZOCILPINE MALEATE; ELECTROPHYSIOLOGY; EXCITATORY AMINO ACID AGONISTS; EXCITATORY AMINO ACID ANTAGONISTS; FEMALE; GLUTAMIC ACID; GLYCINE; HINDLIMB SUSPENSION; MICROINJECTIONS; NEURONS; QUINOXALINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GLUTAMATE; RED NUCLEUS; STIMULATION, CHEMICAL; WEIGHTLESSNESS SIMULATION;

EID: 56249142282     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2008.10.044     Document Type: Article

References (19)

1. Buckeye Jar J.C., Lane L.D., Levine B.D., Watenpaugh D.E., Wright S.J., Moore W.E., Gaffney F.A., and Blomqvist C.G. Orthostatic intolerance after spaceflight. J. Appl. Physiol. 81 (1996) 7-18
2. Bi L., Li Y.X., He M., Huang Z.M., Zhao D.S., and Lan J.Q. Ultrastructural changes in cerebral cortex and cerebellar cortex of rats under simulated weightlessness. Space Med. Med. Eng. (Beijing) 17 (2004) 180-183
3. Davies J., Qume M., and Harris N.C. Pharmacological characterization of excitatory synaptic transmission in the cat red nucleus in vivo. Brain Res. 27 (1994) 43-52
4. Davies J., Miller A.J., and Sheardown M.J. Aminoacid receptor mediated excitatory synaptic transmission in the cat red nucleus. J. Physiol. 376 (1986) 16-29
5. Davies J., Miller A.J., and Sheardown M.J. Amino acid receptor mediated excitatory synaptic transmission in the cat red nucleus. J. Physiol. 376 (1986) 13-29
6. Giuffrida R., Aicardi G., Canedi A., and Rapisarda C. Excitatory amino acids as neurotransmitters of cortical and cerebellar projections to the red nucleus: an immunocytochemical study in the guinea pig. Somatosens. Mot. Res. 10 (1993) 365-376
7. Humphrey D.R., Gold R., and Reed D.J. Sizes, laminar and topographic origins of cortical projections to the major divisions of the red nucleus in the monkey. J. Comp. Neurol. 225 (1984) 75-94
8. Huang H., and van Pol A.N. Rapid direct excitation and long-lasting enhancement of NMDA response by group I metabotropic glutamate receptor activation of hypothalamic melanin-concentrating hormone neurons. J. Neurosci. 27 (2007) 11560-11572
9. Jiang M.C., Alheid G.F., and Nunzi M.G. Cerebellar input to magnocellular neurons in the red nucleus of the mouse: synaptic analysis in horizontal brain slices incorporating cerebello-RN pathways. Neuroscience 110 (2002) 105-121
10. Keifer J., and Houk J.C. Motor function of the cerebellorubrospinal system. Physiol. Rev. 74 (1994) 509-542
11. Morey-Holton E.R., and Globus R.K. Hindlimb unloading rodent model: technical aspects. J. Appl. Physiol. 92 (2002) 1367-1377
12. Musacchia X.J., Steffen J.M., Fell R.D., and Dombrowski M.J. Skeletal muscle response to spaceflight, whole body suspension, and recovery in rats. J. Appl. Physiol. 69 (1990) 2248-2253
13. Newberg A.B., and Alavi A. Changes in the central nervous system during long-duration Space flight: implications for neuro-imaging. Adv. Space Res. 22 (1998) 185-196
14. Paxinos G., and Watson C. The Rat Brain in Stereotaxic Coordinates. 5th ed. (2004), Academic Press, Sydney
15. Sato K., Mick G., Kiyama H., and Tohyama M. Expression patterns of a glutamate-binding protein in the rat central nervous system: comparison with N-methyl-d-aspartate receptor subunit 1 in rat. Neuroscience 64 (1995) 459-475
16. Uva B.M., Masini M.A., Sturla M., Prato P., Passalacqua M., Giuliani M., Tagliafierro G., and Strollo F. Clinorotation-induced weightlessness influences the cytoskeleton of glial cells in culture. Brain Res. 934 (2002) 132-139
17. Wang Z.M., Li Y.Q., and Shi J.W. The localization and distribution of metabotropic glutamate receptor 1 and 1α subtypes in the rat brain. Acta Anat. Sin. 27 (1996) 225-232
18. Zhang S., Tang J.S., Yuan B., and Jia H. Inhibitory effects of glutamate-induced activation of thalamic nucleus submedius are mediated by ventrolateral orbital cortex and periaqueductal gray in rats. Eur. J. Pain 2 (1998) 153-163
19. Zhu Y.J., Wu S.D., and Fan X.L. Effects of simulated weightlessness on ultrastructure of red nucleus neuron of rats. Space Med. Med. Eng. (Beijing) 19 (2006) 23-25