Induction and removal of DNA damage in blood leukocytes of patients with type 2 diabetes mellitus undergoing hemodialysis

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 657, Issue 2, 2008, Pages 111-115

  Bagatini, Pamela Brambilla ^a   Palazzo, Roberta Passos ^a   Rodrigues, Manoela Tressoldi ^a   Costa, Cynthia Hernandes ^a   Maluf, Sharbel Weidner ^b  

^a UNIVERSIDADE FEEVALE   (Brazil)

^b HOSPITAL DE CLÍNICAS DE PORTO ALEGRE   (Brazil)

Author keywords

Comet assay; DNA damage; Hemodialysis; Type 2 diabetes mellitus

Indexed keywords

ADULT; AGED; ARTICLE; BLOOD CELL; COMET ASSAY; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; FEMALE; GENOTOXICITY; HEMODIALYSIS; HUMAN; HUMAN CELL; LEUKOCYTE; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; OXIDATION; PRIORITY JOURNAL; SMOKING;

AGED; COMET ASSAY; DIABETES MELLITUS, TYPE 2; DNA DAMAGE; DNA REPAIR; FEMALE; HUMANS; LEUKOCYTES; MALE; MIDDLE AGED; OXIDATIVE STRESS; RENAL DIALYSIS;

EID: 56249134503     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2008.08.004     Document Type: Article

References (35)

1. Song F., Jia W., Yao Y., Hu Y., Lei L., Lin J., Sun X., and Liu L. Oxidative stress, antioxidant status and DNA damage in patients with impaired glucose regulation and newly diagnosed type 2 diabetes. Clin. Sci. (Lond.) 112 (2007) 599-606
2. Malecki M.T. Type 2 diabetes mellitus and its complications: from the molecular biology to the clinical practice. Rev. Diabet. Stud. 1 (2004) 5-8
3. World Health Organization (WHO), Update: 2007, Available at: http://www.who.int. Accessed May 10, 2007.
4. Malerbi D.A., and Franco L.J. Multicenter study of the prevalence of diabetes mellitus and impaired glucose tolerance in the urban Brazilian population aged 30-69 yr. The Brazilian Cooperative Group on the Study of Diabetes Prevalence. Diabetes Care 15 (1992) 1509-1516
5. Rösen P., Nawroth P.P., King G., Möller W., Tritschler H.J., and Packer L. The role of oxidative stress in the onset and progression of diabetes and its complications: a summary of a Congress Series sponsored by UNESCO-MCBN, the American Diabetes Association and the German Diabetes Society. Diabetes Metab. Res. Rev. 17 (2001) 189-212
6. Miyazaki Y., Kawano H., Yoshida T., Miyamoto S., Hokamaki J., Nagayoshi Y., Yamabe H., Nakamura H., Yodoi J., and Ogawa H. Pancreatic B-cell function is altered by oxidative stress induced by acute hyperglycaemia. Diabet. Med. 24 (2007) 154-160
7. Bonnefont-Rousselot D., Bastard J.P., Jaudon M.C., and Delattre J. Consequences of the diabetic status on the oxidant/antioxidant balance. Diabetes Metab. 26 (2000) 163-176
8. Zhang Y., Zhou J., Wang T., and Cai L. High level glucose increases mutagenesis in human lymphoblastoid cells. Int. J. Biol. Sci. 3 (2007) 375-379
9. Will J.C., Galuska D.A., Vinicor F., and Calle E.E. Colorectal cancer: another complication of diabetes mellitus?. Am. J. Epidemiol. 147 (1998) 816-825
10. Maisonneuve P., Agodoa L., Gellert R., Stewart J.H., Buccianti G., Lowenfels A.B., Wolfe R.A., Jones E., Disney A.P., Briggs D., McCredie M., and Boyle P. Cancer in patients on dialysis for end-stage renal disease: an international collaborative study. Lancet 354 (1999) 93-99
11. Tarng D.C., Tsai T.J., Chen W.T., Liu T.Y., and Wei Y.H. Effect of human OGG1 1245C → G gene polymorphism on 8-hydroxy-2′-deoxyguanosine levels of leukocyte DNA among patients undergoing chronic hemodialysis. J. Am. Soc. Nephrol. 12 (2001) 2338-2347
12. Hwang E.S., and Kim G.H. Biomarkers for oxidative stress status of DNA, lipids, and proteins in vitro and in vivo cancer research. Toxicology 229 (2007) 1-10
13. Singh N.P., McCoy M.T., Tice R.R., and Schneider E.L. A simple technique for quantitation of low levels of DNA damage in individual cells. Exp. Cell Res. 175 (1988) 184-191
14. Ostling O., and Johanson K.J. Microelectrophoretic study of radiation-induced DNA damages in individual mammalian cells. Biochem. Biophys. Res. Commun. 123 (1984) 291-298
15. Carrano A.V., and Natarajan A.T. International Commission for Protection Against Environmental Mutagens and Carcinogens. ICPEMC publication no. 14. Considerations for population monitoring using cytogenetic techniques. Mutat. Res. 204 (1988) 379-406
16. Tice R.R., Agurell E., Anderson D., Burlinson B., Hartmann A., Kobayashi H., Miyamae Y., Rojas E., Ryu J.C., and Sasaki Y.F. Single cell gel/comet assay: guidelines for in vitro and in vivo genetic toxicology testing. Environ. Mol. Mutagen. 35 (2000) 206-221
17. Hartmann A., Agurell E., Beevers C., Brendler-Schwaab S., Burlinson B., Clay P., Collins A., Smith A., Speit G., Thybaud V., and Tice R.R. Recommendations for conducting the in vivo alkaline Comet assay. 4th International Comet Assay Workshop. Mutagenesis 18 (2003) 45-51
18. Nadin S.B., Vargas-Roig L.M., and Ciocca D.R. A silver staining method for single-cell gel assay. J. Histochem. Cytochem. 49 (2001) 1183-1186
19. Maluf S.W., and Erdtmann B. Follow-up study of the genetic damage in lymphocytes of pharmacists and nurses handling antineoplastic drugs evaluated by cytokinesis-block micronuclei analysis and single cell gel electrophoresis assay. Mutat. Res. 471 (2000) 21-27
20. Abramson J.H., and WINPEPI. (PEPI-for-Windows): computer programs for epidemiologists. Epidemiol. Perspect. Innovat. 1 (2004) 6
21. Locatelli F., Pozzoni P., and Del Vecchio L. Renal replacement therapy in patients with diabetes and end-stage renal disease. J. Am. Soc. Nephrol. 15 (2004) S25-S29
22. Ben-Zvi I., Green Y., Nakhoul F., Kanter Y., and Nagler R.M. Effects of diabetes mellitus, chronic renal failure and hemodialysis on serum and salivary antioxidant status. Nephron. Clin. Pract. 105 (2007) 114-120
23. Schupp N., Stopper H., Rutkowski P., Kobras K., Nebel M., Bahner U., Vienken J., and Heidland A. Effect of different hemodialysis regimens on genomic damage in end-stage renal failure. Semin. Nephrol. 26 (2006) 28-32
24. Stopper H., Schupp N., Klassen A., Sebekova K., and Heidland A. Genomic damage in chronic renal failure-potential therapeutic interventions. J. Ren. Nutr. 15 (2005) 81-86
25. Domenici F.A., Vannucchi M.T., Jordão Jr. A.A., Meirelles M.S., and Vannucchi H. DNA oxidative damage in patients with dialysis treatment. Ren. Fail. 27 (2005) 689-694
26. Dinçer Y., Akçay T., Alademir Z., and Ilkova H. Assessment of DNA base oxidation and glutathione level in patients with type 2 diabetes. Mutat. Res. 505 (2002) 75-81
27. Pan H.Z., Chang D., Feng L.G., Xu F.J., Kuang H.Y., and Lu M.J. Oxidative damage to DNA and its relationship with diabetic complications. Biomed. Environ. Sci. 20 (2007) 160-163
28. Stopper H., Boullay F., Heidland A., Vienken J., and Bahner U. Comet-assay analysis identifies genomic damage in lymphocytes of uremic patients. Am. J. Kidney Dis. 38 (2001) 296-301
29. Müller C., Eisenbrand G., Gradinger M., Rath T., Albert F.W., Vienken J., Singh R., Farmer P.B., Stockis J.P., and Janzowski C. Effects of hemodialysis, dialyser type and iron infusion on oxidative stress in uremic patients. Free Radic. Res. 38 (2004) 1093-1100
30. Tarng D.C., Huang T.P., Liu T.Y., Chen H.W., Sung Y.J., and Wei Y.H. Effect of vitamin E-bonded membrane on the 8-hydroxy 2′-deoxyguanosine level in leukocyte DNA of hemodialysis patients. Kidney Int. 58 (2000) 790-799
31. Himmelfarb J., Stenvinkel P., Ikizler T.A., and Hakim R.M. The elephant in uremia: oxidant stress as a unifying concept of cardiovascular disease in uremia. Kidney Int. 62 (2002) 1524-1538
32. Vijayalaxmi, Strauss G.H., and Tice R.R. An analysis of gamma-ray-induced DNA damage in human blood leukocytes, lymphocytes and granulocytes. Mutat. Res. 292 (1993) 123-128
33. Vamvakas S., Bahner U., Becker P., Steinle A., Götz R., and Heidland A. Impairment of DNA repair in the course of long-term hemodialysis and under cyclosporine immunosuppression after renal transplantation. Transplant Proc. 28 (1996) 3468-3473
34. Blasiak J., Arabski M., Krupa R., Wozniak K., Zadrozny M., Kasznicki J., Zurawska M., and Drzewoski J. DNA damage and repair in type 2 diabetes mellitus. Mutat. Res. 554 (2004) 297-304
35. Bonomini M., Forster S., De-Risio F., Rychly J., Nebe B., Manfrini V., Klinkmann H., and Albertazzi A. Effects of selenium supplementation on immune parameters in chronic uraemic patients on haemodialysis. Nephrol. Dial. Transplant. 10 (1995) 1654-1661