Comparative study of desktop- and synchrotron radiation-based micro computed tomography analyzing cell-seeded scaffolds in tissue engineering of bone

Proceedings of SPIE - The International Society for Optical Engineering

Volumn 7078, Issue , 2008, Pages

  Papadimitropoulos, Adam ^a   Friess, Sebastian ^b   Beckmann, Felix ^c   Salmon, Phil ^d   Riboldi, Stefania ^a   Hutmacher, Dietmar ^e   Martin, Ivan ^a   Müller, Bert ^f  

^a UNIVERSITY HOSPITAL BASEL   (Switzerland)

^b Gloor Instruments AG   (Switzerland)

^c INSTITUTE OF MATERIALS RESEARCH   (Germany)

^d SkyScan NV ^*  (Belgium)

^e QUEENSLAND UNIVERSITY OF TECHNOLOGY   (Australia)

^f UNIVERSITY OF BASEL   (Switzerland)

Author keywords

Micro computed tomography; Morphometry; Porosity; Rigid registration; Scaffold; Tissue engineering

Indexed keywords

ANIMAL CELL CULTURE; BONE; CELL CULTURE; CELL GROWTH; CELLS; CHEMICAL REACTORS; COMPUTERIZED TOMOGRAPHY; CYTOLOGY; DIAGNOSTIC RADIOGRAPHY; ELECTRIC INSTRUMENT TRANSFORMERS; ELECTROMAGNETIC WAVES; FADING (RADIO); IMAGE ANALYSIS; IMAGING SYSTEMS; MEDICAL IMAGING; QUANTUM OPTICS; RADIATION EFFECTS; RADIATION HARDENING; RADIATION PROTECTION; SIGNAL TO NOISE RATIO; SYNCHROTRON RADIATION; SYNCHROTRONS; THICKNESS MEASUREMENT; THREE DIMENSIONAL; TISSUE ENGINEERING; TOMOGRAPHY; VEGETATION;

3D CULTURE ENVIRONMENTS; 3D IMAGE ANALYSES; 3D SCAFFOLDS; BEAM HARDENINGS; BELGIUM; CELL CARRIERS; CELL TYPES; CELLULAR MATRIXES; COMPARATIVE STUDIES; CT DEVICES; DENSITY RESOLUTIONS; DESKTOP DEVICES; DYNAMIC RANGES; GERMANY; HUMAN BONES; MICRO COMPUTED TOMOGRAPHIES; MICRO COMPUTED TOMOGRAPHY; MICROMETER RESOLUTIONS; MORPHOMETRY; OSTEOGENIC CELLS; PERFUSION BIOREACTORS; POROUS SCAFFOLDS; RIGID REGISTRATION; SIGNAL-TO-NOISE RATIOS; SPATIAL RESOLUTIONS; SYNCHROTRON RADIATION SOURCES; TISSUE GROWTHS;

SCAFFOLDS;

EID: 56249091070     PISSN: 0277786X     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1117/12.797427     Document Type: Conference Paper

References (39)

1. Yaszemski M.J., Oldham J.B., Lu L., and Currier B.L., [Bone Engineering], 1st Edition, Em Squared ed 1994, p. 541.
2. H. Hatano, A. Ogose, T. Hotta, N. Endo, H. Umezu, and T. Morita, "Extracorporeal irradiated autogenous osteochondral graft: a histological study," J. Bone Joint Surg. Br., 87(7), pp. 1006-1011, July2005.
3. C. R. Perry, "Bone repair techniques, bone graft, and bone graft substitutes," Clin. Orthop. Relat Res.,(360), pp. 71-86, Mar.1999.
4. G. L. Le, P. Layrolle, and G. Daculsi, "A review of bioceramics and fibrin sealant," Eur. Cell Mater., 8, pp. 1-10, 2004.
5. W. L. Fodor, "Tissue engineering and cell based therapies, from the bench to the clinic: the potential to replace, repair and regenerate," Reprod. Biol. Endocrinol., 1, p. 102, Nov.2003.
6. C. M. Agrawal and R. B. Ray, "Biodegradable polymeric scaffolds for musculoskeletal tissue engineering," J. Biomed. Mater. Res., 55(2), pp. 141-150, May2001.
7. D. W. Hutmacher, "Scaffolds in tissue engineering bone and cartilage," Biomaterials, 21(24), pp. 2529-2543, Dec.2000.
8. K. F. Leong, C. M. Cheah, and C. K. Chua, "Solid freeform fabrication of three-dimensional scaffolds for engineering replacement tissues and organs," Biomaterials, 24(13), pp. 2363-2378, June2003.
9. G. Vunjak-Novakovic and L. E. Freed, "Culture of organized cell communities," Adv. Drug Deliv. Rev., 33(1-2), pp. 15-30, Aug.1998.
10. S. Yang, K. F. Leong, Z. Du, and C. K. Chua, "The design of scaffolds for use in tissue engineering. Part I. Traditional factors," Tissue Eng, 7(6), pp. 679-689, Dec.2001.
11. F. C. Fierz, F. Beckmann, M. Huser, S. H. Irsen, B. Leukers, F. Witte, O. Degistirici, A. Andronache, M. Thie, and B. Muller, "The morphology of anisotropic 3D-printed hydroxyapatite scaffolds," Biomaterials, 29(28), pp. 3799-3806, Oct.2008.
12. A. I. Caplan and S. P. Bruder, "Mesenchymal stem cells: building blocks for molecular medicine in the 21st century," Trends Mol. Med., 7(6), pp. 259-264, June2001.
13. P. Bashkin, S. Doctrow, M. Klagsbrun, C. M. Svahn, J. Folkman, and I. Vlodavsky, "Basic fibroblast growth factor binds to subendothelial extracellular matrix and is released by heparitinase and heparin-like molecules," Biochemistry, 28(4), pp. 1737-1743, Feb.1989.
14. E. Schonherr and H. J. Hausser, "Extracellular matrix and cytokines: a functional unit," Dev. Immunol., 7(2-4), pp. 89-101, 2000.
15. H. Castano-Izquierdo, J. varez-Barreto, D. J. van den, J. A. Jansen, A. G. Mikos, and V. I. Sikavitsas, "Pre-culture period of mesenchymal stem cells in osteogenic media influences their in vivo bone forming potential," J. Biomed. Mater. Res. A, 82(1), pp. 129-138, July2007.
16. X. Yu, E. A. Botchwey, E. M. Levine, S. R. Pollack, and C. T. Laurencin, "Bioreactor-based bone tissue engineering: the influence of dynamic flow on osteoblast phenotypic expression and matrix mineralization," Proc. Natl. Acad. Sci. U. S. A, 101(31), pp. 11203-11208, Aug.2004.
17. V. I. Sikavitsas, G. N. Bancroft, H. L. Holtorf, J. A. Jansen, and A. G. Mikos, "Mineralized matrix deposition by marrow stromal osteoblasts in 3D perfusion culture increases with increasing fluid shear forces," Proc. Natl. Acad. Sci. U. S. A, 100(25), pp. 14683-14688, Dec.2003.
18. V. I. Sikavitsas, G. N. Bancroft, J. J. Lemoine, M. A. Liebschner, M. Dauner, and A. G. Mikos, "Flow perfusion enhances the calcified matrix deposition of marrow stromal cells in biodegradable nonwoven fiber mesh scaffolds," Ann. Biomed. Eng, 33(1), pp. 63-70, Jan.2005.
19. G. H. van Lenthe, H. Hagenmuller, M. Bohner, S. J. Hollister, L. Meinel, and R. Muller, "Nondestructive micro-computed tomography for biological imaging and quantification of scaffold-bone interaction in vivo," Biomaterials, 28(15), pp. 2479-2490, May2007.
20. V. S. Komlev, F. Peyrin, M. Mastrogiacomo, A. Cedola, A. Papadimitropoulos, F. Rustichelli, and R. Cancedda, "Kinetics of in vivo bone deposition by bone marrow stromal cells into porous calcium phosphate scaffolds: an X-ray computed microtomography study," Tissue Eng, 12(12), pp. 3449-3458, Dec.2006.
21. M. Mastrogiacomo, A. Papadimitropoulos, A. Cedola, F. Peyrin, P. Giannoni, S. G. Pearce, M. Alini, C. Giannini, A. Guagliardi, and R. Cancedda, "Engineering of bone using bone marrow stromal cells and a silicon-stabilized tricalcium phosphate bioceramic: evidence for a coupling between bone formation and scaffold resorption," Biomaterials, 28(7), pp. 1376-1384, Mar.2007.
22. A. Papadimitropoulos, M. Mastrogiacomo, F. Peyrin, E. Molinari, V. S. Komlev, F. Rustichelli, and R. Cancedda, "Kinetics of in vivo bone deposition by bone marrow stromal cells within a resorbable porous calcium phosphate scaffold: an X-ray computed microtomography study," Biotechnol. Bioeng., 98(1), pp. 271-281, Sept.2007.
23. K. Balto, R. Muller, D. C. Carrington, J. Dobeck, and P. Stashenko, "Quantification of periapical bone destruction in mice by micro-computed tomography," J. Dent. Res., 79(1), pp. 35-40, Jan.2000.
24. R. E. Guldberg, A. S. Lin, R. Coleman, G. Robertson, and C. Duvall, "Microcomputed tomography imaging of skeletal development and growth," Birth Defects Res. C. Embryo. Today, 72(3), pp. 250-259, Sept.2004.
25. R. Muller, T. Hildebrand, H. J. Hauselmann, and P. Ruegsegger, "In vivo reproducibility of three-dimensional structural properties of noninvasive bone biopsies using 3D-pQCT," J. Bone Miner. Res., 11(11), pp. 1745-1750, Nov.1996.
26. R. Muller, M. Hahn, M. Vogel, G. Delling, and P. Ruegsegger, "Morphometric analysis of noninvasively assessed bone biopsies: comparison of high-resolution computed tomography and histologic sections," Bone, 18(3), pp. 215-220, Mar.1996.
27. E. Tanck, J. Homminga, G. H. van Lenthe, and R. Huiskes, "Increase in bone volume fraction precedes architectural adaptation in growing bone," Bone, 28(6), pp. 650-654, June2001.
28. T. Yamashita, Y. Nabeshima, and M. Noda, "High-resolution micro-computed tomography analyses of the abnormal trabecular bone structures in klotho gene mutant mice," J. Endocrinol., 164(2), pp. 239-245, Feb.2000.
29. A. Braccini, D. Wendt, C. Jaquiery, M. Jakob, M. Heberer, L. Kenins, A. Wodnar-Filipowicz, R. Quarto, and I. Martin, "Three-dimensional perfusion culture of human bone marrow cells and generation of osteoinductive grafts," Stem Cells, 23(8), pp. 1066-1072, Sept.2005.
30. D. W. Hutmacher, T. Schantz, I. Zein, K. W. Ng, S. H. Teoh, and K. C. Tan, "Mechanical properties and cell cultural response of polycaprolactone scaffolds designed and fabricated via fused deposition modeling," J. Biomed. Mater. Res., 55(2), pp. 203-216, May2001.
31. D. Wendt, A. Marsano, M. Jakob, M. Heberer, and I. Martin, "Oscillating perfusion of cell suspensions through three-dimensional scaffolds enhances cell seeding efficiency and uniformity," Biotechnol. Bioeng., 84(2), pp. 205-214, Oct.2003.
32. F. Beckmann, Donath T., Fischer J., Dose T., Lippmann T., and Lottermoser R.et al., "New developments for synchrotron-radiation-based microtomography at DESY," In: Bonse U, editor. Developments in X-Ray tomography V, 2006, San Diego:SPIE, 2006.
33. B. Muller, F. Beckmann, M. Huser, F. Maspero, G. Szekely, K. Ruffieux, P. Thurner, and E. Wintermantel, "Nondestructive three-dimensional evaluation of a polymer sponge by micro-tomography using synchrotron radiation," Biomol. Eng, 19(2-6), pp. 73-78, Aug.2002.
34. A.C. Kak and M. Slaney, [Principles of computerized tomographic imaging]. Philadelphia: SIAM, 2001.
35. P. Thurner, F. Beckmann, and B. Muller, "An optimization procedure for spatial and density resolution in hard X-ray micro-computed tomography," Nucl Intrum Meth Phys Res B, 225(4), pp. 599-603, 2004.
36. F. Maes, A. Collignon, D. Vandermeulen, G. Marchal, and P. Suetens, "Multi-modality image registration by maximation of mutual information," Mathematical Methods in Biomedical Image Analysis, pp. 14-22, 1996.
37. P. Viola and W. M. Wells, "Alignment by maximation of mutual information," Fifth International Conference on Computer Vision, IEEE Computer Society, 1995.
38. W. H. Press, B. P. Flannery, S. A. Teukolsky, and W. T. Vetterling, [The Art of Scientific Computing] Cambridge University Press, 1988.
39. R. Müller, S. Matter, P. Neuenschwander, U. V. Suter, and P. Rüegsegger, "3D micro-tomographic imaging and quantitative morphometry for the nondestructive evaluation of porous biomaterials.," Morphological Control in Multiphase Polymer Mixtures, Mat Res Soc, 461, pp. 217-221, 1997.