A lipid-parameter-based index for estimating insulin sensitivity and identifying insulin resistance in a healthy population

Diabetes and Metabolism

Volumn 34, Issue 5, 2008, Pages 457-463

  Disse, E ^a,b,c,d   Bastard, J P ^e,f   Bonnet, F ^a,b,c,d   Maitrepierre, C ^a,b,c,d   Peyrat, J ^a,b,c,d   Louche Pelissier, C ^a,b,c,d   Laville, M ^a,b,c,d  

^a EDOUARD HERRIOT HOSPITAL   (France)

^b INSERM   (France)

^c CEMAGREF   (France)

^d UNIVERSITÉ DE LYON   (France)

^e HÔPITAL TENON   (France)

^f CENTRE DE RECHERCHE SAINT ANTOINE   (France)

Author keywords

Diabetes; Fatty acids; Insulin resistance; ROC curve; Surrogate markers

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BIOLOGICAL MARKER; C PEPTIDE; CHOLESTEROL; GAMMA GLUTAMYLTRANSFERASE; GLUCAGON; GLUCOSE; HIGH DENSITY LIPOPROTEIN; INSULIN; PROINSULIN; TRIACYLGLYCEROL;

ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANTHROPOMETRIC PARAMETERS; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BLOOD PRESSURE; BLOOD SAMPLING; BODY MASS; CHOLESTEROL BLOOD LEVEL; FEMALE; GAMMA GLUTAMYL TRANSFERASE BLOOD LEVEL; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE; HUMAN; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; INSULIN SENSITIVITY; MALE; NORMAL HUMAN; PROTEIN BLOOD LEVEL; TRIACYLGLYCEROL BLOOD LEVEL;

ADULT; ALANINE TRANSAMINASE; ASPARTATE AMINOTRANSFERASES; BLOOD GLUCOSE; BODY MASS INDEX; FASTING; FATTY ACIDS, NONESTERIFIED; GLUCAGON; GLUCOSE CLAMP TECHNIQUE; HUMANS; INSULIN; INSULIN RESISTANCE; LIPIDS; MIDDLE AGED; PROINSULIN; REFERENCE VALUES; WAIST-HIP RATIO;

EID: 56149127081     PISSN: 12623636     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.diabet.2008.02.009     Document Type: Article

References (26)

1. Reaven G.M. Banting lecture 1988. Role of insulin resistance in human disease. Diabetes 37 (1988) 1595-1607
2. DeFronzo R.A., Tobin J.D., and Andres R. Glucose clamp technique: a method for quantifying insulin secretion and resistance. Am J Physiol 237 (1979) E214-E223
3. Yeni-Komshian H., Carantoni M., Abbasi F., and Reaven G.M. Relationship between several surrogate estimates of insulin resistance and quantification of insulin-mediated glucose disposal in 490 healthy nondiabetic volunteers. Diabetes Care 23 (2000) 171-175
4. McAuley K.A., Williams S.M., Mann J.I., Walker R.J., Lewis-Barned N.J., Temple L.A., et al. Diagnosing insulin resistance in the general population. Diabetes Care 24 (2001) 460-464
5. Malita F.M., Karelis A.D., St-Pierre D.H., Garrel D., Bastard J.P., Tardif A., et al. Surrogate indexes vs. euglycaemic-hyperinsulinemic clamp as an indicator of insulin resistance and cardiovascular risk factors in overweight and obese postmenopausal women. Diabetes Metab 32 (2006) 251-255
6. Hills S.A., Balkau B., Coppack S.W., Dekker J.M., Mari A., Natali A., et al. The EGIR-RISC STUDY (The European group for the study of insulin resistance: relationship between insulin sensitivity and cardiovascular disease risk): I. Methodology and objectives. Diabetologia 47 (2004) 566-570
7. Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Diabetes Care 1997; 20:1183-97.
8. Alberti K.G., and Zimmet P.Z. Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation. Diabet Med 15 (1998) 539-553
9. Ducluzeau P.H., Perretti N., Laville M., Andreelli F., Vega N., Riou J.P., et al. Regulation by insulin of gene expression in human skeletal muscle and adipose tissue. Evidence for specific defects in type 2 diabetes. Diabetes 50 (2001) 1134-1142
10. Ferrannini E., and Mari A. How to measure insulin sensitivity. J Hypertens 16 (1998) 895-906
11. Matthews D.R., Hosker J.P., Rudenski A.S., Naylor B.A., Treacher D.F., and Turner R.C. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28 (1985) 412-419
12. Katz A., Nambi S.S., Mather K., Baron A.D., Follmann D.A., Sullivan G., et al. Quantitative insulin sensitivity check index: a simple, accurate method for assessing insulin sensitivity in humans. J Clin Endocrinol Metab 85 (2000) 2402-2410
13. Perseghin G., Caumo A., Caloni M., Testolin G., and Luzi L. Incorporation of the fasting plasma FFA concentration into QUICKI improves its association with insulin sensitivity in nonobese individuals. J Clin Endocrinol Metab 86 (2001) 4776-4781
14. Hanley J.A., and McNeil B.J. A method of comparing the areas under receiver operating characteristic curves derived from the same cases. Radiology 148 (1983) 839-843
15. Matsuda M., and DeFronzo R.A. Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp. Diabetes Care 22 (1999) 1462-1470
16. Stumvoll M., Mitrakou A., Pimenta W., Jenssen T., Yki-Jarvinen H., Van Haeften T., et al. Use of the oral glucose tolerance test to assess insulin release and insulin sensitivity. Diabetes Care 23 (2000) 295-301
17. Karelis A.D., Pasternyk S.M., Messier L., St-Pierre D.H., Lavoie J.M., Garrel D., et al. Relationship between insulin sensitivity and the triglyceride-HDL-C ratio in overweight and obese postmenopausal women: a MONET study. Appl Physiol Nutr Metab 32 (2007) 1089-1096
18. Abbasi F., McLaughlin T., Lamendola C., and Reaven G.M. The relationship between glucose disposal in response to physiological hyperinsulinemia and basal glucose and free fatty acid concentrations in healthy volunteers. J Clin Endocrinol Metab 85 (2000) 1251-1254
19. Jeppesen J., Facchini F.S., and Reaven G.M. Individuals with high total cholesterol/HDL cholesterol ratios are insulin resistant. J Intern Med 243 (1998) 293-298
20. Robins S.J., Rubins H.B., Faas F.H., Schaefer E.J., Elam M.B., Anderson J.W., et al. Insulin resistance and cardiovascular events with low HDL cholesterol: the Veterans Affairs HDL Intervention Trial (VA-HIT). Diabetes Care 26 (2003) 1513-1517
21. Hayden M.R., and Tyagi S.C. Isolated low high density lipoprotein-cholesterol (HDL-C): implications of global risk reduction. Case report and systematic scientific review. Cardiovasc Diabetol 4 (2005) 1
22. Drexel H., Aczel S., Marte T., Benzer W., Langer P., Moll W., et al. Is atherosclerosis in diabetes and impaired fasting glucose driven by elevated LDL cholesterol or by decreased HDL cholesterol?. Diabetes Care 28 (2005) 101-107
23. Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III). JAMA 2001; 285:2486-97.
24. Alberti K.G., Zimmet P., and Shaw J. The metabolic syndrome-a new worldwide definition. Lancet 366 (2005) 1059-1062
25. Holman R.R., Coleman R.L., Shine B.S., and Stevens R.J. Non-HDL cholesterol is less informative than the total-to-HDL cholesterol ratio in predicting cardiovascular risk in type 2 diabetes. Diabetes Care 28 (2005) 1796-1797
26. Bhalodkar N.C., Blum S., and Enas E.A. Accuracy of the ratio of triglycerides to high-density lipoprotein cholesterol for predicting low-density lipoprotein cholesterol particle sizes, phenotype B, and particle concentrations among Asian Indians. Am J Cardiol 97 (2006) 1007-1009