Phage-display derived single-chain fragment variable (scFv) antibodies recognizing conformational epitopes of Escherichia coli heat-labile enterotoxin B-subunit

Journal of Immunological Methods

Volumn 339, Issue 2, 2008, Pages 115-123

  Chung, Wen Yuan ^a,g   Sack, Markus ^b   Carter, Rachel ^c   Spiegel, Holger ^d   Fischer, Rainer ^b,d   Hirst, Timothy R ^e   Williams, Neil A ^f   James, Roger F L ^g  

^a ROYAL COLLEGE OF SURGEONS IN IRELAND   (Ireland)

^b RWTH AACHEN UNIVERSITY   (Germany)

^c UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^d FRAUNHOFER INSTITUTE FOR MOLECULAR BIOLOGY AND APPLIED ECOLOGY IME   (Germany)

^e Australian National University   (Australia)

^f UNIVERSITY OF BRISTOL   (United Kingdom)

^g UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

Differential recognition; Epitope; EtxB; Phage display; Protein assembly; Recombinant antibodies; scFvs

Indexed keywords

EPITOPE; ESCHERICHIA COLI ENTEROTOXIN; ESCHERICHIA COLI ENTEROTOXIN B1; ESCHERICHIA COLI ENTEROTOXIN B5; MONOCLONAL ANTIBODY; RECOMBINANT ANTIBODY; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY; UNCLASSIFIED DRUG;

ANTIGEN BINDING; ANTIGEN RECOGNITION; ARTICLE; BINDING COMPETITION; BINDING KINETICS; ENZYME LINKED IMMUNOSORBENT ASSAY; MOLECULAR CLONING; NONSENSE MUTATION; PHAGE DISPLAY; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DENATURATION; SEQUENCE ANALYSIS;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODY SPECIFICITY; BACTERIAL TOXINS; BINDING SITES, ANTIBODY; CROSS REACTIONS; ENTEROTOXINS; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITOPES; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; G(M1) GANGLIOSIDE; IMMUNOGLOBULIN VARIABLE REGION; PROTEIN STRUCTURE, QUATERNARY; RECOMBINANT PROTEINS; SEQUENCE ANALYSIS, DNA;

ESCHERICHIA COLI;

EID: 56049110502     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jim.2008.08.005     Document Type: Article

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