Acid-degradable polyurethane particles for protein-based vaccines: Biological evaluation and in vitro analysis of particle degradation products

Molecular Pharmaceutics

Volumn 5, Issue 5, 2008, Pages 876-884

  Bachelder, Eric M ^a,b   Beaudette, Tristan T ^a,b   Broaders, Kyle E ^a,b   Paramonov, Sergey E ^a,b   Dashe, Jesse ^a,b   Fréchet, Jean M J ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

Author keywords

Acid degradable materials; CTL; LC MS; Microparticles; Polyacetal; Vaccination

Indexed keywords

OVALBUMIN; POLYURETHAN; VACCINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN PRESENTATION; ARTICLE; BIODEGRADABILITY; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DENDRITIC CELL; DRUG SYNTHESIS; EXOCYTOSIS; FEMALE; IN VITRO STUDY; INCUBATION TIME; LC 50; LIGHT SCATTERING; LIQUID CHROMATOGRAPHY; MACROPHAGE; MASS SPECTROMETRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; TOXICITY TESTING; TRANSMISSION ELECTRON MICROSCOPY; VACCINATION; VACCINE PRODUCTION;

ACIDS; ANIMALS; ANTIGEN PRESENTATION; CELLS, CULTURED; DRUG CARRIERS; FEMALE; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; IMMUNODOMINANT EPITOPES; LIGHT; MACROPHAGES; MICE; MICE, INBRED C57BL; MICROSCOPY, ELECTRON, TRANSMISSION; MOLECULAR STRUCTURE; NANOPARTICLES; OVALBUMIN; PARTICLE SIZE; POLYURETHANES; PROTEINS; SCATTERING, RADIATION; T-LYMPHOCYTES, CYTOTOXIC; VACCINES;

EID: 56049107315     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp800068x     Document Type: Article

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