The clinicopathological and prognostic impact of 14-3-3 sigma expression on vulvar squamous cell carcinomas

BMC Cancer

Volumn 8, Issue , 2008, Pages

  Wang, Zhihui ^a,b,c   Tropè, Claes G ^a,c   Suo, Zhenhe ^a,c   Trøen, Gunhild ^a   Yang, Guanrui ^b   Nesland, Jahn M ^a,c   Holm, Ruth ^a  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

^b ZHENGZHOU UNIVERSITY   (China)

^c UNIVERSITY OF OSLO   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; RNA; STRATIFIN; CELL CYCLE PROTEIN; EXONUCLEASE; MESSENGER RNA; SFN PROTEIN, HUMAN; TUMOR MARKER; TUMOR PROTEIN; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CANCER CELL CULTURE; CANCER CHEMOTHERAPY; CANCER INVASION; CANCER RADIOTHERAPY; CANCER SURVIVAL; CARCINOGENESIS; CELL NUCLEUS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOPLASM; DOWN REGULATION; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LASER CAPTURE MICRODISSECTION; MAJOR CLINICAL STUDY; PROGNOSIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ISOLATION; SQUAMOUS CELL CARCINOMA; VULVA CARCINOMA; VULVECTOMY; ANALYSIS OF VARIANCE; DISEASE FREE SURVIVAL; GENETICS; METABOLISM; MIDDLE AGED; PATHOLOGY; RETROSPECTIVE STUDY; TUMOR CELL LINE; VULVA; VULVA TUMOR;

ADULT; AGED; AGED, 80 AND OVER; ANALYSIS OF VARIANCE; CARCINOMA, SQUAMOUS CELL; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CELL NUCLEUS; CYTOPLASM; DISEASE-FREE SURVIVAL; DOWN-REGULATION; EXONUCLEASES; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MIDDLE AGED; NEOPLASM PROTEINS; RETROSPECTIVE STUDIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TUMOR MARKERS, BIOLOGICAL; VULVA; VULVAR NEOPLASMS;

EID: 55949136396     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-8-308     Document Type: Article

References (43)

1. Coulter J Gleeson N Local and regional recurrence of vulval cancer: management dilemmas Best Pract Res Clin Obstet Gynaecol 2003, 17:663-681. 10.1016/S1521-6934(03)00050-6 12965138
2. Jones RW Baranyai J Stables S Trends in squamous cell carcinoma of the vulva: The influence of vulvar intraepithelial neoplasia Obstet Gynecol 1997, 90:448-452. 10.1016/S0029-7844(97)00298-6 9277660
3. Messing MJ Gallup DG Carcinoma of the vulva in young women Obstet Gynecol 1995, 86:51-54. 10.1016/0029-7844(95)00101-V 7784022
4. Tyring SK Vulvar squamous cell carcinoma: Guidelines for early diagnosis and treatment Am J Obstet Gynecol 2003, 189:S17-S23. 10.1067/ S0002-9378(03)00792-0 14532899
5. Qi W Liu X Qiao D Martinez JD Isoform-specific expression of 14-3-3 proteins in human lung cancer tissues Int J Cancer 2005, 113:359-363. 10.1002/ijc.20492 15455356
6. Yaffe MB Rittinger K Volinia S Caron PR Aitken A Leffers H The structural basis for 14-3-3:pHosphopeptide binding specificity cell 1997, 91:961-971. 10.1016/S0092-8674(00)80487-0 9428519
7. Dougherty MK Morrison DK Unlocking the code of 14-3-3 J Cell Sci 2004, 117:1875-1884. 10.1242/jcs.01171 15090593
8. Fu H Subramanian RR Masters SC 14-3-3 proteins: Structure, function, and regulation Annu Rev Pharmacol Toxicol 2000, 40:617-647. 10.1146/ annurev.pharmtox.40.1.617 10836149
9. Mackintosh C Dynamic interactions between 14-3-3 proteins and phosphoproteins regulate diverse cellular processes Biochem J 2004, 381:329-342. 1133837 15167810 10.1042/BJ20031332
10. Hermeking H Lengauer C Polyak K He TC Zhang L Thiagalingam S 14-3-3 sigma is a p53-regulated inhibitor of G2/M progression Mol cell 1997, 1:3-11. 10.1016/S1097-2765(00)80002-7 9659898
11. Lakin ND Jackson SP Regulation of p53 in response to DNA damage Oncogene 1999, 18:7644-7655. 10.1038/sj.onc.1203015 10618704
12. Taylor WR Stark GR Regulation of the G2/M transition by p53 Oncogene 2001, 20:1803-1815. 10.1038/sj.onc.1204252 11313928
13. Laronga C Yang HY Neal C Lee MH Association of the cyclin-dependent kinases and 14-3-3 sigma negatively regulates cell cycle progression J Biol Chem 2000, 275:23106-23112. 10.1074/jbc.M905616199 10767298
14. Chan TA Hermeking H Lengauer C Kinzler KW Vogelstein B 14-3-3Sigma is required to prevent mitotic catastrophe after DNA damage Nature 1999, 401:616-620. 10.1038/44188 10524633
15. Ferguson AT Evron E Umbricht CB Pandita TK Chan TA Hermeking H High frequency of hypermethylation at the 14-3-3 sigma locus leads to gene silencing in breast cancer Proc Natl Acad Sci USA 2000, 97:6049-6054. 18556 10811911 10.1073/pnas.100566997
16. Iwata N Yamamoto H Sasaki S Itoh F Suzuki H Kikuchi T Frequent hypermethylation of CpG islands and loss of expression of the 14-3-3 sigma gene in human hepatocellular carcinoma Oncogene 2000, 19:5298-5302. 10.1038/sj.onc.1203898 11077447
17. Lodygin D Yazdi AS Sander CA Herzinger T Hermeking H Analysis of 14-3-3sigma expression in hyperproliferative skin diseases reveals selective loss associated with CpG-methylation in basal cell carcinoma Oncogene 2003, 22:5519-5524. 10.1038/sj.onc.1206854 12934112
18. Lodygin D Diebold J Hermeking H Prostate cancer is characterized by epigenetic silencing of 14-3-3sigma expression Oncogene 2004, 23:9034-9041. 10.1038/sj.onc.1208004 15489902
19. Moreira JM Gromov P Celis JE Expression of the tumor suppressor protein 14-3-3 sigma is down-regulated in invasive transitional cell carcinomas of the urinary bladder undergoing epithelial-to-mesenchymal transition Mol Cell Proteomics 2004, 3:410-419. 10.1074/mcp.M300134-MCP200 14736829
20. Suzuki H Itoh F Toyota M Kikuchi T Kakiuchi H Imai K Inactivation of the 14-3-3 sigma gene is associated with 5' CpG island hypermethylation in human cancers Cancer Res 2000, 60:4353-4357. 10969776
21. Yatabe Y Osada H Tatematsu Y Mitsudomi T Takahashi T Decreased expression of 14-3-3sigma in neuroendocrine tumors is independent of origin and malignant potential Oncogene 2002, 21:8310-8319. 10.1038/ sj.onc.1206014 12447694
22. Simpson PT Gale T Reis-Filho JS Jones C Parry S Steele D Distribution and significance of 14-3-3sigma, a novel myoepithelial marker, in normal, benign, and malignant breast tissue J Pathol 2004, 202:274-285. 10.1002/path.1530 14991892
23. Ito K Suzuki T Akahira J Sakuma M Saitou S Okamoto S 14-3-3sigma in endometrial cancer - a possible prognostic marker in early-stage cancer Clin Cancer Res 2005, 11:7384-7391. 10.1158/1078-0432.CCR-05-0187 16243811
24. Perathoner A Pirkebner D Brandacher G Spizzo G Stadlmann S Obrist P 14-3-3sigma expression is an independent prognostic parameter for poor survival in colorectal carcinoma patients Clin cancer Res 2005, 11:3274-3279. 10.1158/1078-0432.CCR-04-2207 15867223
25. Gasco M Sullivan A Repellin C Brooks L Farrell PJ Tidy JA Coincident inactivation of 14-3-3sigma and p16INK4a is an early event in vulval squamous neoplasia Oncogene 2002, 21:1876-1881. 10.1038/sj.onc.1205256 11896620
26. Shepherd JH Cervical and vulva cancer: Changes in FIGO definitions of staging Br J Obstet Gynaecol 1996, 103:405-406. 8624311
27. WHO Pathology and Genetics Tumours of the Breast and Female Genital Organs World Health Organization Classification of Tumors Lyon: IARC Press 2003:316-321.
28. Knopp S Bjorge T Nesland JM Trope C Scheistroen M Holm R p16INK4a and p21Waf1/Cip1 expression correlates with clinical outcome in vulvar carcinomas Gynecol Oncol 2004, 95:37-45. 10.1016/j.ygyno.2004.07.026 15385108
29. Knopp S Bjorge T Nesland JM Trope C Holm R Cyclins D1, D3, E, and A in vulvar carcinoma patients Gynecol Oncol 2005, 97:733-739. 10.1016/ j.ygyno.2005.03.025 15894358
30. Knopp S Nesland JM Trope C Holm R p14ARF, a prognostic predictor in HPV-negative vulvar carcinoma Am J Clin Pathol 2006, 126:266-276. 10.1309/E9E8Y9WG5QE3LK29 16891203
31. Scheistroen M Trope C Kaern J Pettersen EO Alfsen GC Nesland JM DNA ploidy and expression of p53 and C-erbB-2 in extramammary Paget's disease of the vulva Gynecol Oncol 1997, 64:88-92. 10.1006/ gyno.1996.4517 8995553
32. Nakajima T Shimooka H Weixa P Segawa A Motegi A Jian Z Immunohistochemical demonstration of 14-3-3 sigma protein in normal human tissues and lung cancers, and the preponderance of its strong expression in epithelial cells of squamous cell lineage Pathol Int 2003, 53:353-360. 10.1046/j.1440-1827.2003.01481.x 12787309
33. Kurokawa I Mizutani H Kusumoto K Nishijima S Tsujita-Kyutoku M Shikata N Cytokeratin, filaggrin, and p63 expression in reepithelialization during human cutaneous wound healing Wound Repair Regen 2006, 14:38-45. 10.1111/ j.1524-475X.2005.00086.x 16476070
34. Ghahary A Marcoux Y Karimi-Busheri F Li Y Tredget EE Kilani RT Differentiated keratinocyte-releasable stratifin (14-3-3 sigma) stimulates MMP-1 expression in dermal fibroblasts J Invest Dermatol 2005, 124:170-177. 10.1111/j.0022-202X.2004.23521.x 15654971
35. Mhawech P Greloz V Assaly M Herrmann F Immunohistochemical expression of 14-3-3 sigma protein in human urological and gynecological tumors using a multi-tumor microarray analysis Pathol Int 2005, 55:77-82. 10.1111/ j.1440-1827.2004.01797.x 15693853
36. Bhatia K Siraj AK Hussain A Bu R Gutierrez MI The tumor suppressor gene 14-3-3 sigma is commonly methylated in normal and malignant lymphoid cells Cancer Epidemiol Biomarkers Prev 2003, 12:165-169. 12582028
37. Mhawech P 14-3-3 proteins - an update Cell Res 2005, 15:228-236. 10.1038/ sj.cr.7290291 15857577
38. van Hemert MJ Niemantsverdriet M Schmidt T Backendorf C Spaink HP Isoform-specific differences in rapid nucleocytoplasmic shuttling cause distinct subcellular distributions of 14-3-3 sigma and 14-3-3 zeta J Cell Sci 2004, 117:1411-1420. 10.1242/jcs.00990 14996909
39. Piwnica-Worms H Cell cycle. Fools rush in Nature 1999, 401:535-537. 10.1038/44029 10524615
40. Tanaka K Hatada T Kobayashi M Mohri Y Tonouchi H Miki C The clinical implication of 14-3-3 sigma expression in primary gastrointestinal malignancy Int J Oncol 2004, 25:1591-1597. 15547695
41. Akahira J Sugihashi Y Suzuki T Ito K Niikura H Moriya T Decreased expression of 14-3-3 sigma is associated with advanced disease in human epithelial ovarian cancer: Its correlation with aberrant DNA methylation Clin cancer Res 2004, 10:2687-2693. 10.1158/1078-0432.CCR-03-0510 15102672
42. Sano T Shimooka H Weixa P Segawa A Jian Z Motegi A Immunohistochemical expression of 14-3-3 sigma protein in various histological subtypes of uterine cervical cancers Pathol Int 2004, 54:743-750. 10.1111/ j.1440-1827.2004.01747.x 15482563
43. Audic Y Hartley RS Post-transcriptional regulation in cancer Biol Cell 2004, 96:479-498. 10.1016/j.biolcel.2004.05.002 15380615