Risk of recurrence in surgically resected stage I adenocarcinoma of the lung: Histopathologic and immunohistochemical analysis

Lung

Volumn 186, Issue 6, 2008, Pages 411-419

  Cho, Sukki ^a   Sung, Sook Whan ^a   Jheon, Sanghoon ^a,b   Chung, Jin Haeng ^a,b  

^a Seoul National University Bundang Hospital   (South Korea)

^b Seoul National University College of Medicine   (South Korea)

Author keywords

Adenocarcinoma; Lung cancer; Prognostic factors; Recurrence; Stage I

Indexed keywords

CYCLIN D; EPIDERMAL GROWTH FACTOR RECEPTOR; KI 67 ANTIGEN; MOLECULAR MARKER; PROTEIN P53; UVOMORULIN;

ADULT; AGED; ARTICLE; CANCER RECURRENCE; CANCER STAGING; CANCER SURGERY; COMPUTER ASSISTED TOMOGRAPHY; DISEASE FREE SURVIVAL; FEMALE; FOLLOW UP; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LOBECTOMY; LUNG ADENOCARCINOMA; LYMPH NODE DISSECTION; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; MEDIASTINUM LYMPH NODE; NECROSIS; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PROGNOSIS; RECURRENCE RISK; RISK ASSESSMENT; TUMOR BIOPSY; TUMOR DIFFERENTIATION; TUMOR VOLUME;

ADENOCARCINOMA; AGED; CADHERINS; DISEASE-FREE SURVIVAL; FEMALE; FOLLOW-UP STUDIES; HUMANS; IMMUNOHISTOCHEMISTRY; KI-67 ANTIGEN; LUNG NEOPLASMS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; NEOPLASM RECURRENCE, LOCAL; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; RECURRENCE; RISK; TUMOR MARKERS, BIOLOGICAL; TUMOR SUPPRESSOR PROTEIN P53;

EID: 55949133107     PISSN: 03412040     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00408-008-9116-4     Document Type: Article

References (26)

1. Travis WD, Colby TV, Corrin B (1999) Histological typing of lung and pleural tumors, 3rd edn. OMS Springer, Heidelberg
2. CF Mountain JM Lukeman SP Hammar 1987 Lung cancer classification: the relationship of disease extent and cell type to survival in a clinical trials population J Surg Oncol 35 147 156 10.1002/jso.2930350302
3. JC Nesbitt JB Putnam Jr GL Walsh JA Roth CF Mountain 1995 Survival in early-stage non-small cell lung cancer Ann Thorac Surg 60 466 472 10.1016/0003-4975(95)00169-L
4. G Cox JL Jones A Andi DA Waller KJ O'Byme 2001 A biological staging model for operable non-small cell lung cancer Thorax 56 561 566 10.1136/thorax.56.7. 561
5. DH Harpole Jr WG Richards JE Herndon II DJ Sugarbaker 1996 Angiogenesis and molecular biologic substaging in patients with stage I non-small cell lung cancer Ann Thorac Surg 61 1470 1476 10.1016/0003-4975(96)00104-X
6. GM Strauss DJ Kwiatowski DH Harpole TJ Lynch AT Skarin DJ Sugarbaker 1995 Molecular and pathologic marker in stage I non-small cell lung carcinoma of the lung J Clin Oncol 13 1265 1279
7. IG Duarte BL Bufkin MF Pennington AA Gal C Cohen AS Kosinski KA Mansour JI Miller 1998 Angiogenesis a predictor of survival after surgical resection for stage I non-small cell lung cancer J Thorac Cardiovasc Surg 115 652 659 10.1016/S0022-5223(98)70331-9
8. DC Quinlan AG Davidson CL Summers HE Warden HM Doshi 1992 Accumulation of p53 proteins correlates with a poor prognosis in human lung cancer Cancer Res 52 4828 4831
9. C Poleri JL Morero B Nieva MF Vázquez C Rodríguez E de Titto M Rosenberg 2003 Risk of recurrence in patients with surgically resected stage I non-small cell lung carcinoma: histopathologic and immunohistochemical analysis Chest 123 1858 1867 10.1378/chest.123.6.1858
10. GM Strauss J Herndon MA Maddaus 2006 Adjuvant chemotherapy in stage IB NSCLC: update of CALGB protocol 9633. ASCO Annual Meeting Proceedings J Clin Oncol 24 7007
11. H Kato Y Ichinose M Ohta E Hata N Tsubota H Tada Y Watanabe H Wada M Tsuboi N Hamajima M Ohta Japan Lung Cancer Research Group on Postsurgical Adjuvant Chemotherapy 2004 A randomized trial of adjuvant chemotherapy with uracil-tegafur for adenocarcinoma of the lung N Engl J Med 350 1713 1721 10.1056/NEJMoa032792
12. P Macchiarini G Fontanini MJ Hardin H Chuanchieh D Bigini S Vignati R Pingitore CA Angeletti 1993 Blood vessel invasion by tumor cells predicts recurrence in completely resected T1N0M0 non-small cell lung cancer J Thorac Cardiovasc Surg 106 80 89
13. PA Thomas L Rubinstein 1990 Cancer recurrence after resection: T1 N0 non-small cell lung cancer Ann Thorac Surg 49 242 247
14. A Takise A Kodama Y Shimosato S Watanabe K Suemasu 1988 Histologic prognostic factors in adenocarcinoma of the lung periphery less than 2 cm in diameter Cancer 61 2083 2088 10.1002/1097-0142(19880515)61:10<2083::AID- CNCR2820611025>3.0.CO;2-U
15. PC Pairolero DE Williams EJ Bergstralh PE Bernatz WS Payne 1984 Postsurgical stage I bronchogenic carcinoma: morbid implications of recurrent disease Ann Thorac Surg 38 331 336
16. N Kobayashi S Toyooka J Soh K Ichimura H Yanai H Suehisa S Ichihara M Yamane M Aoe Y Sano H Date 2007 Risk factors for recurrence and unfavorable prognosis in patients with stage I non-small cell lung cancer and a tumor diameter of 20 mm or less J Thorac Oncol 2 808 812 10.1097/JTO.0b013e31814617c7
17. T Fujisawa Y Yamaguchi Y Saitoh K Hiroshima H Ohwada 1995 Blood and lymphatic vessel invasion as prognostic factors for patients with primary resected nonsmall cell carcinoma of the lung with intrapulmonary metastases Cancer 76 2464 2470 10.1002/1097-0142(19951215)76:12<2464::AID- CNCR2820761210>3.0.CO;2-U
18. Y Ichinose T Yano H Yokoyama T Inoue H Asoh Y Katsuda 1994 The correlation between tumor size and lymphatic vessel invasion in resected peripheral stage I non-small cell lung cancer J Thorac Cardiovasc Surg 108 684 686
19. TA D'Amico M Massey JE Herndon II MB Moore DH Harpole 1999 A biologic risk model for stage I lung cancer: immunohistochemical analysis of 408 patients with the use of ten molecular markers J Thorac Cardiovasc Surg 117 736 743 10.1016/S0022-5223(99)70294-1
20. D Lane 1992 p53, guardian of the genome Nature 358 15 16 10.1038/358015a0
21. P Dalquen G Sauter J Torhorst E Schultheiss P Jordan S Lehmann M Solèr P Stulz MJ Mihatsch F Gudat 1996 Nuclear p53 overexpression is an independent prognostic parameter in node-negative non-small cell lung carcinoma J Pathol 178 53 58 10.1002/(SICI)1096-9896(199601)178:1<53::AID-PATH415>3. 0.CO;2-T
22. T Mitsudomi N Hamajima M Ogawa T Takahashi 2000 Prognostic significance of p53 alterations in patients with non-small cell lung cancer: A meta-analysis Clin Cancer Res 6 4055 4063
23. E Steels M Paesmans T Berghmans F Branle F Lemaitre C Mascaux AP Meert F Vallot JJ Lafitte JP Sculier 2001 Role of p53 as a prognostic factor for survival in lung cancer: as systemic review of the literature with a meta-analysis Eur Respir J 18 705 719 10.1183/09031936.01.00062201
24. D Liu C Huang K Kameyama E Hayashi A Yamauchi S Kobayashi H Yokomise 2001 E-cadherin expression associated with differentiation and prognosis in patients with non-small cell lung cancer Ann Thorac Surg 71 949 955 10.1016/S0003- 4975(00)02545-5
25. S Kase K Sugio K Yamazaki T Okamoto T Yano K Sugimachi 2000 Expression of E-cadherin and b-catenin in human non-small cell lung cancer and the clinical significance Clin Cancer Res 6 4789 4796
26. C Lu JC Soria X Tang XC Xu L Wanag L Mao R Lotan B Kemp BN Bekele L Feng WK Hong FR Khuri 2004 Prognostic factors in resected stage I non-small cell lung cancer: a Multivariate analysis of six molecular markers J Clin Oncol 22 4575 4583 10.1200/JCO.2004.01.091