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Volumn 178, Issue 1, 1996, Pages 53-58

Nuclear p53 overexpression is an independent prognostic parameter in node-negative non-small cell lung carcinoma

Author keywords

Immunohistochemistry; Non small cell lung carcinoma; p53; Prognosis; Survival

Indexed keywords

PROTEIN P53;

EID: 13244300654     PISSN: 00223417     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9896(199601)178:1<53::AID-PATH415>3.0.CO;2-T     Document Type: Article
Times cited : (50)

References (41)
  • 2
    • 0026329930 scopus 로고
    • Surgical treatment of lung cancer
    • Mountain CF. Surgical treatment of lung cancer. Rev Oncoll Hematol 1991; 11: 179-207.
    • (1991) Rev Oncoll Hematol , vol.11 , pp. 179-207
    • Mountain, C.F.1
  • 4
    • 0027109075 scopus 로고
    • p53, guardian of the genome
    • Lane D p53, guardian of the genome. Nature 1992; 358: 15-16.
    • (1992) Nature , vol.358 , pp. 15-16
    • Lane, D.1
  • 6
    • 0027406235 scopus 로고
    • Prognostic significance of p53 overexpression in node-negative breast carcinomas: Preliminary studies support cautious optimism
    • Thor AD, Yandell DW. Prognostic significance of p53 overexpression in node-negative breast carcinomas: preliminary studies support cautious optimism J Natl Cancer Inst 1993; 85: 176-177
    • (1993) J Natl Cancer Inst , vol.85 , pp. 176-177
    • Thor, A.D.1    Yandell, D.W.2
  • 7
    • 0026651717 scopus 로고
    • Small subgroup of aggressive, highly proliferative prostatic carcinomas denned by p53 accumulation
    • Visakorpi T, Kallioniemi OP, Heikkinen A, Koivula T, Isola J. Small subgroup of aggressive, highly proliferative prostatic carcinomas denned by p53 accumulation. J Natl Cancer Inst 1992; 84: 883-887.
    • (1992) J Natl Cancer Inst , vol.84 , pp. 883-887
    • Visakorpi, T.1    Kallioniemi, O.P.2    Heikkinen, A.3    Koivula, T.4    Isola, J.5
  • 8
    • 0027301174 scopus 로고
    • p53 Nuclear overexpression and disease progression in Ta bladder carcinoma
    • Sarkis AS, Zhang ZF, Cordon CC, et al. p53 Nuclear overexpression and disease progression in Ta bladder carcinoma Int J Oncol 1993; 3: 355-360.
    • (1993) Int J Oncol , vol.3 , pp. 355-360
    • Sarkis, A.S.1    Zhang, Z.F.2    Cordon, C.C.3
  • 9
    • 0025265724 scopus 로고
    • Increased expression of mutant forms of p53 oncogene in primary lung cancer
    • Iggo R, Gatter KC, Bartek J, Lane DP, Harris AL. Increased expression of mutant forms of p53 oncogene in primary lung cancer. Lancet 1990; 335: 675-679
    • (1990) Lancet , vol.335 , pp. 675-679
    • Iggo, R.1    Gatter, K.C.2    Bartek, J.3    Lane, D.P.4    Harris, A.L.5
  • 10
  • 11
    • 0026737950 scopus 로고
    • Accumulation of p53 protein correlates with a poor prognosis in human lung cancer
    • Quinlan DC, Davidson AG, Summers CL, Warden HE, Doshi HM. Accumulation of p53 protein correlates with a poor prognosis in human lung cancer. Cancer Res 1992; 52: 4828-4831.
    • (1992) Cancer Res , vol.52 , pp. 4828-4831
    • Quinlan, D.C.1    Davidson, A.G.2    Summers, C.L.3    Warden, H.E.4    Doshi, H.M.5
  • 12
    • 0027717341 scopus 로고
    • Immunohistochemical study of p53 in human lung carcinomas
    • Brambilla E, Gazzeri S, Moro D, et al Immunohistochemical study of p53 in human lung carcinomas. Am J Pathol 1993; 143: 199-210.
    • (1993) Am J Pathol , vol.143 , pp. 199-210
    • Brambilla, E.1    Gazzeri, S.2    Moro, D.3
  • 13
    • 0028224376 scopus 로고
    • Relationship of p53 overexpression and up-regulation of proliferating cell nuclear antigen with the clinical course of non-small cell lung cancer
    • Ebina M, Steinberg SM, Mulshine JL, Linnoila RI. Relationship of p53 overexpression and up-regulation of proliferating cell nuclear antigen with the clinical course of non-small cell lung cancer. Cancer Res 1994; 54: 2496-2503.
    • (1994) Cancer Res , vol.54 , pp. 2496-2503
    • Ebina, M.1    Steinberg, S.M.2    Mulshine, J.L.3    Linnoila, R.I.4
  • 14
    • 0027473475 scopus 로고
    • Prognostic significance of p53 mutations and 3p deletions in primary resected non-small cell lung cancer
    • Horio Y, Takahashi T, Kuroishi T, et al. Prognostic significance of p53 mutations and 3p deletions in primary resected non-small cell lung cancer. Cancer Res 1993, 53: 1-4
    • (1993) Cancer Res , vol.53 , pp. 1-4
    • Horio, Y.1    Takahashi, T.2    Kuroishi, T.3
  • 15
    • 0025047766 scopus 로고
    • Mutations m the p53 gene are frequent in primary, resected non-small cell lung cancer
    • Chiba I, Takahashi T, Nau MM, et al. Mutations m the p53 gene are frequent in primary, resected non-small cell lung cancer. Oncogene 1990; 5: 1603-1610.
    • (1990) Oncogene , vol.5 , pp. 1603-1610
    • Chiba, I.1    Takahashi, T.2    Nau, M.M.3
  • 16
    • 0026051751 scopus 로고
    • Detection of p53 in primary lung tumors and non-small cell lung carcinoma cell lines
    • Caamano J, Ruggeri B, Momiki S, Sickler A, Zhang SY, Klein SAJ. Detection of p53 in primary lung tumors and non-small cell lung carcinoma cell lines. Am J Pathol 1991; 139: 839-845.
    • (1991) Am J Pathol , vol.139 , pp. 839-845
    • Caamano, J.1    Ruggeri, B.2    Momiki, S.3    Sickler, A.4    Zhang, S.Y.5    Klein, S.A.J.6
  • 17
    • 0026673041 scopus 로고
    • Aberrations of the p53 tumor suppressor gene in human non-small cell carcinomas of the lung
    • Kishimoto Y, Murakami Y, Shiraishi M, Hayashi K, Sekiya T Aberrations of the p53 tumor suppressor gene in human non-small cell carcinomas of the lung. Cancer Res 1992; 52: 4799-4804.
    • (1992) Cancer Res , vol.52 , pp. 4799-4804
    • Kishimoto, Y.1    Murakami, Y.2    Shiraishi, M.3    Hayashi, K.4    Sekiya, T.5
  • 18
    • 0026543204 scopus 로고
    • p53 gene mutations in non-small-cell lung cancer cell lines and their correlation with the presence of ras mutations and clinical features
    • Mitsudomi T, Steinberg SM, Nau MM, et al. p53 gene mutations in non-small-cell lung cancer cell lines and their correlation with the presence of ras mutations and clinical features. Oncogene 1992; 7: 171-180.
    • (1992) Oncogene , vol.7 , pp. 171-180
    • Mitsudomi, T.1    Steinberg, S.M.2    Nau, M.M.3
  • 20
    • 0027731662 scopus 로고
    • p53 expression in oat and non-oat small cell lung carcinomas; correlations with proliferating cell nuclear antigen
    • Korkolopoulou P, Oates J, Crocker J, Edwards C. p53 expression in oat and non-oat small cell lung carcinomas; correlations with proliferating cell nuclear antigen. J Clin Pathol 1993; 46: 1093-1096.
    • (1993) J Clin Pathol , vol.46 , pp. 1093-1096
    • Korkolopoulou, P.1    Oates, J.2    Crocker, J.3    Edwards, C.4
  • 21
    • 0027174951 scopus 로고
    • p53 alterations in non-small cell lung cancers correlate with metastatic involvement of hilar and mediastinal lymph nodes
    • Marchetti A, Buttitta F, Merlo G, et al. p53 alterations in non-small cell lung cancers correlate with metastatic involvement of hilar and mediastinal lymph nodes Cancer Res 1993; 53: 2846-2851.
    • (1993) Cancer Res , vol.53 , pp. 2846-2851
    • Marchetti, A.1    Buttitta, F.2    Merlo, G.3
  • 22
    • 0027499196 scopus 로고
    • Overexpression of the p53 tumor suppressor gene product in primary lung adenocarcinomas is associated with cigarette smoking
    • Westra WH, Offerhaus GJA, Goodman SN, et al. Overexpression of the p53 tumor suppressor gene product in primary lung adenocarcinomas is associated with cigarette smoking. Am J Surg Pathol 1993, 17: 213-220.
    • (1993) Am J Surg Pathol , vol.17 , pp. 213-220
    • Westra, W.H.1    Offerhaus, G.J.A.2    Goodman, S.N.3
  • 24
    • 13344291560 scopus 로고
    • Geneva: WHO
    • The World Health Organization. Histologic Typing of Lung Cancer Geneva: WHO, 1981: 89: 1595-1602
    • (1981) Histologic Typing of Lung Cancer , vol.89 , pp. 1595-1602
  • 25
    • 0027443536 scopus 로고
    • p53 and erbB-2 protein overexpression are associated with early invasion and metastasis in bladder cancer
    • Moch H, Sauter G, Moore D, Mihatsch MJ, Gudat F, Waldman F. p53 and erbB-2 protein overexpression are associated with early invasion and metastasis in bladder cancer. Virchows Arch A 1993; 423: 329 334.
    • (1993) Virchows Arch A , vol.423 , pp. 329334
    • Moch, H.1    Sauter, G.2    Moore, D.3    Mihatsch, M.J.4    Gudat, F.5    Waldman, F.6
  • 27
  • 28
    • 0027489384 scopus 로고
    • Clinical implications of the p53 tumor-suppressor gene
    • Harris CC, Hollstein M, Clinical implications of the p53 tumor-suppressor gene. N Engl J Med 1993; 329: 1318-1327.
    • (1993) N Engl J Med , vol.329 , pp. 1318-1327
    • Harris, C.C.1    Hollstein, M.2
  • 29
    • 0028299342 scopus 로고
    • p53 in tumour pathology can we trust immunocytochemistry? - Revisited!
    • Hall PA, Lane DP. p53 in tumour pathology can we trust immunocytochemistry? - revisited! J Pathol 1994; 172: 1-4.
    • (1994) J Pathol , vol.172 , pp. 1-4
    • Hall, P.A.1    Lane, D.P.2
  • 30
    • 0023959795 scopus 로고
    • Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life
    • Finlay C, Hinds P, Tan T, Eliyahu D, Oren M, Levine A. Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life. Mol Cell Biol 1988; 8: 531-539.
    • (1988) Mol Cell Biol , vol.8 , pp. 531-539
    • Finlay, C.1    Hinds, P.2    Tan, T.3    Eliyahu, D.4    Oren, M.5    Levine, A.6
  • 31
    • 0021616838 scopus 로고
    • UV irradiation stimulates levels of p53 cellular tumor antigen in nontransformed mouse cells
    • Maltzman W, Czyzyk L. UV irradiation stimulates levels of p53 cellular tumor antigen in nontransformed mouse cells. Mol Cell Biol 1984; 4: 1689-1694.
    • (1984) Mol Cell Biol , vol.4 , pp. 1689-1694
    • Maltzman, W.1    Czyzyk, L.2
  • 33
    • 0028207349 scopus 로고
    • An evaluation of six antibodies for immunohistochemistry of mutant p53 gene product in archival colorectal neoplasms
    • Baas I, Mulder J, Offerhaus J, Vogelstein B, Hamilton S. An evaluation of six antibodies for immunohistochemistry of mutant p53 gene product in archival colorectal neoplasms. J Pathol 1994; 172: 13-18.
    • (1994) J Pathol , vol.172 , pp. 13-18
    • Baas, I.1    Mulder, J.2    Offerhaus, J.3    Vogelstein, B.4    Hamilton, S.5
  • 34
    • 0026609019 scopus 로고
    • Expression of mutant p53 proteins in lung cancer correlates with the class of p53 gene mutation
    • Bodner SM, Minna JD, Jensen SM, et al Expression of mutant p53 proteins in lung cancer correlates with the class of p53 gene mutation. Oncogene 1992; 7: 743-749
    • (1992) Oncogene , vol.7 , pp. 743-749
    • Bodner, S.M.1    Minna, J.D.2    Jensen, S.M.3
  • 35
    • 0026597191 scopus 로고
    • p53 mutations in non-small cell lung cancer in Japan: Association between mutations and smoking
    • Suzuki H, Takahashi T, Kuroishi T, et al. p53 mutations in non-small cell lung cancer in Japan: association between mutations and smoking Cancer Res 1992; 52: 734-736
    • (1992) Cancer Res , vol.52 , pp. 734-736
    • Suzuki, H.1    Takahashi, T.2    Kuroishi, T.3
  • 36
    • 0028176307 scopus 로고
    • p53 mutations in lung tumors, relationship to putative susceptibility markers for cancer
    • Ryberg D, Kure E, Lystad S, et al. p53 mutations in lung tumors, relationship to putative susceptibility markers for cancer. Cancer Res 1994; 54: 1551-1555
    • (1994) Cancer Res , vol.54 , pp. 1551-1555
    • Ryberg, D.1    Kure, E.2    Lystad, S.3
  • 37
    • 0018947744 scopus 로고
    • Classification and prognosis of surgically treated patients with bronchial carcinoma: Analysis of VASOG studies
    • Shields TW. Classification and prognosis of surgically treated patients with bronchial carcinoma: analysis of VASOG studies. Int J Radiation Oncol Biol Phys 1980, 6: 1021-1027.
    • (1980) Int J Radiation Oncol Biol Phys , vol.6 , pp. 1021-1027
    • Shields, T.W.1
  • 38
    • 0019857126 scopus 로고
    • Survival after surgical treatment according to stage, histologic type and immunomorphologic changes in regional lymph nodes
    • Tosi P, Luzi P, Leoncini L, Miracco C, Gambacorta M, Grossi A. Survival after surgical treatment according to stage, histologic type and immunomorphologic changes in regional lymph nodes Cancer 1981; 48: 2288-2295.
    • (1981) Cancer , vol.48 , pp. 2288-2295
    • Tosi, P.1    Luzi, P.2    Leoncini, L.3    Miracco, C.4    Gambacorta, M.5    Grossi, A.6
  • 39
    • 0021344541 scopus 로고
    • A retrospective analysis of 10-year survivors from carcinoma of the lung
    • Temeck BK, Flehinger BJ, Martini N. A retrospective analysis of 10-year survivors from carcinoma of the lung Cancer 1984, 53: 1405-1408
    • (1984) Cancer , vol.53 , pp. 1405-1408
    • Temeck, B.K.1    Flehinger, B.J.2    Martini, N.3
  • 40
    • 0022416803 scopus 로고
    • Prognostic factors of bronchogenic carcinoma patients: Clinical and post-operative staging, histological grading
    • Kayser KW, Heinrich S, Toomes H, Klimek M. Prognostic factors of bronchogenic carcinoma patients: clinical and post-operative staging, histological grading. Tumor Diagn Ther 1985; 6: 149-154.
    • (1985) Tumor Diagn Ther , vol.6 , pp. 149-154
    • Kayser, K.W.1    Heinrich, S.2    Toomes, H.3    Klimek, M.4
  • 41
    • 0027407120 scopus 로고
    • Gastric cancer with p53 overexpression has high potential for metastasising to lymph nodes
    • Kakeji Y, Korenaga D, Tsujitani S, et al. Gastric cancer with p53 overexpression has high potential for metastasising to lymph nodes Br J Cancer 1993; 67: 589-593.
    • (1993) Br J Cancer , vol.67 , pp. 589-593
    • Kakeji, Y.1    Korenaga, D.2    Tsujitani, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.