Negative effect of leptin on bone mass in type 1 diabetes

Acta Diabetologica

Volumn 45, Issue 4, 2008, Pages 237-241

  Kassem, Hania S ^a   Arabi, Asma ^a   Zantout, Mira S ^a   Azar, Sami T ^a  

^a AMERICAN UNIVERSITY OF BEIRUT   (Lebanon)

Author keywords

Bone; Bone mineral density; Leptin; Osteoporosis; Type 1 diabetes

Indexed keywords

HEMOGLOBIN A1C; LEPTIN;

ADULT; ANALYTIC METHOD; ARTICLE; BODY COMPOSITION; BODY HEIGHT; BODY MASS; BODY WEIGHT; BONE DENSITY; BONE MASS; BONE MINERAL; CLINICAL ARTICLE; CROSS-SECTIONAL STUDY; DIABETIC PATIENT; DISEASE DURATION; FAT BODY; FEMALE; HORMONE ACTION; HORMONE BLOOD LEVEL; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; MALE; METABOLIC REGULATION; MICROALBUMINURIA; PRIORITY JOURNAL;

ADIPOSE TISSUE; AGE OF ONSET; BODY MASS INDEX; BONE DENSITY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DIABETES MELLITUS, TYPE 1; FEMALE; HEMOGLOBIN A, GLYCOSYLATED; HUMANS; INSULIN; LEPTIN; MALE; YOUNG ADULT;

EID: 55949108685     PISSN: 09405429     EISSN: 14325233     Source Type: Journal    
DOI: 10.1007/s00592-008-0050-y     Document Type: Article

References (33)

1. ME Levin VC Boisseau LV Avioli 1976 Effects of diabetes mellitus on bone mass in juvenile and adult-onset diabetes N Engl J Med 294 5 241 245
2. P McNair C Christiansen MS Christensen S Madsbad OK Faber C Binder I Transbol 1981 Development of bone mineral loss in insulin-treated diabetes: a 1 1/2 years follow-up study in sixty patients Eur J Clin Invest 11 1 55 59
3. SL Hui S Epstein CC Johnston Jr 1985 A prospective study of bone mass in patients with type I diabetes J Clin Endocrinol Metab 60 1 74 80
4. JM Olmos JL Perez-Castrillon MT Garcia JC Garrido JA Amado J Gonzalez-Macias 1994 Bone densitometry and biochemical bone remodeling markers in type 1 Diabetes Mellitus Bone Miner 26 1 1 8
5. T Miazgowski S Czekalski 1998 A 2-year follow-up study on bone mineral density and markers of bone turnover in patients with long-standing insulin-dependent diabetes mellitus Osteoporos Int 8 5 399 403
6. A Rozadilla JM Nolla E Montana J Fiter C Gomez-Vaquero J Soler D Roig-Escofet 2000 Bone mineral density in patients with type 1 diabetes mellitus Jt Bone Spine 67 3 215 218
7. V Bartos A Jirkovska P Kasalicky A Smahelova K Vondra J Skibova 2001 Osteopenia and osteoporosis in diabetic women over 40 years of age Cas Lek Cesk 140 10 299 301
8. PJ Lopez-Ibarra MM Pastor F Escobar-Jimenez MD Pardo AG Gonzalez JD Luna ME Requena MA Diosdado 2001 Bone mineral density at time of clinical diagnosis of adultonset type 1 diabetes mellitus Endocr Pract 7 5 346 351
9. DL Chau SV Edelman M Chandran 2003 Osteoporosis and diabetes Curr Diabetes Rep 3 1 37 42
10. T Thomas F Gori S Khosla MD Jensen B Buerguera BL Riggs 1999 Leptin acts on human marrow stromal cells to enhance differentiation to osteoblasts and to inhibit differentiation to adipocytes Endocrinology 140 1630 1638
11. T Thomas B Burguera 2002 Mini review: is leptin the link between fat and bone mass? J Bone Miner Res 17 1563 1569
12. A Goulding RW Taylor 1998 Plasma leptin values in relation to bone mass and density and to dynamic biochemical markers of bone resorption and formation in postmenopausal women Calcif Tissue Int 63 456 458
13. F Rauch WF Blum K Klein B Allolio E Schonau 1998 Does leptin have an effect on bone in adult women? Calcif Tissue Int 63 453 455
14. D Kiel T Harris M Visser M Hannan P Wilson 1999 Leptin and bone mineral density (BMD) in older men and women J Bone Miner Res 14 475 765
15. E Odabasi M Ozata M Turan N Bingol A Yonem B Cakir M Kutlu IC Ozdemir 2000 Plasma leptin concentrations in postmenopausal women with osteoporosis Eur J Endocrinol 142 170 173
16. G Martini R Valenti S Giovani B Franci S Campagna R Nuti 2001 Influence of insulin-like growth factor-1 and leptin on bone mass in healthy postmenopausal women Bone 28 113 117
17. CE Ruhl JE Everhart 2002 Relationship of serum leptin concentration with bone mineral density in the United States population J Bone Miner Res 17 1896 1903
18. AM Johnstone SD Murison JS Duncan KA Rance JR Speakman 2005 Factors influencing variation in basal metabolic rate include fat-free mass, fat mass, age, and circulating thyroxine but not sex, circulating leptin, or triiodothyronine Am J Clin Nutr 82 5 941 948
19. V Matkovic JZ Ilich M Skugor NE Badenhop P Goel A Clairmont D Klisovic RHW Nahhas JO Landoll 1997 Leptin is inversely related to age at menarche in human females J Clin Endocrinol Metab 82 3239 3245
20. I Iwamoto T Oouchi A Kosha M Murakami T Fujino Y Nagata 2000 Relationships between serum leptin level and regional bone mineral density, bone metabolic markers in healthy women Acta Obstet Gynecol Scandinavica 79 1060 1064
21. JA Pasco MJ Henry MA Kotowicz GR Collier MJ Ball AM Ugoni GC Nicholson 2001 Serum leptin levels are associated with bone mass in nonobese women J Clin Endocrinol Metab 86 1884 1887
22. M Yamauchi T Sugimoto T Yamaguchi D Nakaoka M Kanzawa S Yano R Ozuru T Sugishita K Chihara 2001 Plasma leptin concentrations are associated with bone mineral density and the presence of vertebral fractures in postmenopausal women Clin Endocrinol 55 341 347
23. S Ormarsdottir O Ljunggren H Mallmin H Olofsson WF Blum L Loof 2001 Inverse relationship between circulating levels of leptin and bone mineral density in chronic liver disease J Gastroenterol Hepatol 16 1409 1414
24. M Sato N Takeda H Sarui R Takami K Takami M Hayashi A Sasaki S Kawachi K Yoshino K Yasuda 2001 Association between serum leptin concentrations and bone mineral density, and biochemical markers of bone turnover in adult men J Clin Endocrinol Metab 86 5273 5276
25. M Blum SS Harris A Must EN Naumova SM Phillips WM Rand B Dawson- Hughes 2003 Leptin, body composition and bone mineral density in premenopausal women Calcif Tissue Int 73 1 27 32
26. C Morberg I Tetens E Black S Toubro T Soerensen O Pedersen A Astrup 2003 Leptin and bone mineral density: a cross-sectional study in obese and nonobese men J Clin Endocrinol Metab 88 12 5795 5800
27. M Kontogianni U Dafni J Routsias F Skopouli 2004 Blood leptin and adiponectin as possible mediators of the relation between fat mass and BMD in perimenopausal women J Bone Miner Res 19 546 551
28. R Abou Samra N Baba N Torbay L Dib GE Fuleihan 2005 High plasma leptin is not associated with higher bone mineral density in insulin-resistant premenopausal obese women J Clin Endocrinol Metab 90 2588 2594
29. O Alexopoulou J Jamart JP Devogelaer S Brichard P de Nayer M Buysschaert 2006 Bone density and markers of bone remodeling in type 1 male diabetic patients Diabetes Metab 32 453 458
30. E Vina Simon G Bueno Lozano MI Armada Maresca JL Ruibal Francisco C Fernandez Perez C Lozano Tonkin E Casado de Frias 2000 Bone mineral density in juvenile-onset diabetes mellitus An Esp Pediatr 52 6 507 515
31. P Ducy M Amling S Takeda M Priemel AF Schilling FT Beil J Shen C Vinson JM Rueger G Karsenty 2000 Leptin inhibits bone formation through a hypothalamic relay: a central control of bone mass Cell 100 197 207
32. S Watanabe Y Takeuchi S Fukumoto H Fujita T Nakano T Fujita 2003 Decrease in serum leptin by troglitazone is associated with preventing bone loss in type 2 diabetic patients J Bone Miner Metab 21 3 166 171
33. F Lönnqvist P Arner L Nordfors M Schalling 1995 Overexpression of the obese (ob) gene in adipose tissue of human obese subjects Nat Med 1 950 953