Combination of KIR 2DL2 and HLA-C1 (Asn80) confers susceptibility to type 1 diabetes in Latvians

International Journal of Immunogenetics

Volumn 35, Issue 6, 2008, Pages 439-446

  Shastry, A ^b   Sedimbi, S K ^b   Rajalingam, R ^c   Nikitina Zake, L ^b   Rumba, I ^d   Wigzell, H ^b   Sanjeevi, C B ^a,b  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF LATVIA   (Latvia)

Author keywords

[No Author keywords available]

Indexed keywords

HLA ANTIGEN CLASS 1; IMMUNOGLOBULIN RECEPTOR; KILLER IMMUNOGLOBULIN LIKE RECEPTOR 2DL2; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; ARTICLE; CHILD; CONTROLLED STUDY; FALSE POSITIVE RESULT; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENOTYPE; HAPLOTYPE; HUMAN; IMMUNE RESPONSE; INFANT; INSULIN DEPENDENT DIABETES MELLITUS; LATVIA; MAJOR CLINICAL STUDY; PRIORITY JOURNAL;

ADOLESCENT; CHILD; CHILD, PRESCHOOL; DIABETES MELLITUS, TYPE 1; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HLA-C ANTIGENS; HUMANS; INFANT; INFANT, NEWBORN; LATVIA; MALE; RECEPTORS, KIR2DL2;

EID: 55949093468     PISSN: 17443121     EISSN: 1744313X     Source Type: Journal    
DOI: 10.1111/j.1744-313X.2008.00804.x     Document Type: Article

References (37)

1. Alizadeh, B.Z., Eerligh, P., van der Slik, A.R., Shastry, A., Zhernakova, A., Valdigem, G. et al 2007) MICA marks additional risk factors for type 1 diabetes on extended HLA haplotypes: an association and meta-analysis. Molecular Immunology, 11, 2806.
2. Arnheim, L., Dillner, J. Sanjeevi, C.B. (2005) A population-based cohort study of KIR genes and genotypes in relation to cervical intraepithelial neoplasia. Tissue Antigens, 65, 252.
3. Biassoni, R., Pessino, A., Malaspina, A., Cantoni, C., Bottino, C., Sivori, S., Moretta, L. Moretta, A. (1997) Role of amino acid position 70 in the binding affinity of p50.1 and p58.1 receptors for HLA-Cw4 molecules. European Journal of Immunology, 27, 3095.
4. Boyington, J.C. Sun, P.D. (2002) A structural perspective on MHC class I recognition by killer cell immunoglobulin-like receptors. Molecular Immunology, 38, 1007
5. Carrington, M., Wang, S., Martin, M.P., Gao, X., Schiffman, M., Cheng, J. et al 2005) Hierarchy of resistance to cervical neoplasia mediated by combinations of killer immunoglo bulin-like receptor and human leukocyte antigen loci. Journal of Experimental Medicine, 201, 1069.
6. Flodstrom, M., Maday, A., Balakrishna, D., Cleary, M.M., Yoshimura, A. Sarvetnick, N. (2002) Target cell defense prevents the development of diabetes after viral infection. Nature Immunology, 3, 373.
7. Gambelunghe, G., Ghaderi, M., Cosentino, A., Falorni, A., Brunetti, P., Falorni, A. Sanjeevi, C.B. (2000) Association of MHC class I chain-related A (MIC-A) gene polymorphism with type I diabetes. Diabetologia, 43, 507.
8. Hiby, S.E., Walker, J.J., O'shaughnessy, K.M., Redman, C.W., Carrington, M., Trowsdale, J. Moffett, A. (2004) Combinations of maternal KIR and fetal HLA-C genes influence the risk of pre eclampsia and reproductive success. Journal of Experimental Medicine, 200, 957.
9. Hsu, K.C., Chida, S., Geraghty, D.E. Dupont, B. (2002) The killer cell immunoglobulin-like receptor (KIR) genomic region: gene-order, haplotypes and allelic polymorphism. Immunological Reviews, 190, 40.
10. Khakoo, S.I., Thio, C.L., Martin, M.P., Brooks, C.R., Gao, X.-J. Astemborski, J. et al 2004) HLA and NK cell inhibitory receptor genes in resolving hepatitis C virus infection Science, 305, 872.
11. Kumar, D., Gemayel, N.S., Deapen, D., Kapadia, D., Yamashita, P.H., Lee, M., Dwyer, J.H., Roy-Burman, P., Bray, G.A. Mack, T.M. (1993) North American twins with IDDM. Genetic, etiological and clinical significance of disease concordance according to age, zygosity and the interval after diagnosis in first twin. Diabetes, 42, 1351.
12. Lee, I.F., Qin, H., Trudeau, J., Dutz, J. Tan, R. (2004) Regulation of autoimmune diabetes by complete Freund's adjuvant is mediated by NK cells. The Journal of Immunology, 172, 937.
13. Liene, N.Z., Rajalingham, R., Rumba, I. Sanjeevi, C.B. (2004) Killer cell immunoglobulin-like receptor genes in Latvian patients with type 1 diabetes mellitus and healthy controls. Annals of the New York Academy of Sciences, 1037, 161.
14. Martin, M.P., Gao, X., Lee, J.H., Nelson, G.E., Detels, R., Goedert, J.J., Carrington, M. et al 2002) Epistatic interaction between KIR3DS1 and HLA-B delays the progression to AIDS. Nature Genetics, 31, 429.
15. Martin, M.P., Nelson, G., Lee, J.H., Pellett, F., Gao, X., Wade, J., Wilson, M.J., Trowsdale, J., Gladman, D. Carrington, M. (2002) Cutting edge: susceptibility to psoriatic arthritis: influence of activating killer Ig-like receptor genes in the absence of specific HLA-C alleles. The Journal of Immunology, 169, 2818.
16. Middleton, D., Halfpenny, I., Meenagh, A., Williams, F., Sivula, J. Tuomilehto-Wolf, E. (2006) Investigation of KIR gene frequencies in type 1 diabetes mellitus. Human Immunology, 67, 986.
17. Miettinen, O.S. (1976) The estimability and estimation in case-referent studies. American Journal of Epidemiology, 103, 226.
18. Mogami, S., Hasegawa, G., Nakayama, I., Asano, M., Hosoda, H., Kadono, M. et al 2007) Killer cell immunoglobulin-like receptor genotypes in Japanese patients with type 1 diabetes. Tissue Antigens, 70, 506.
19. Momot, T., Koch, S., Hunzelmann, N., Krieg, T., Ulbricht, K., Schmidt, R.E. Witte, T. (2004) Association of killer cell immunoglobulin-like receptors with scleroderma. Arthritis and Rheumatism, 50, 1561.
20. Moretta, A., Bottino, C., Vitale, M., Pende, D., Biassoni, R., Mingari, M.C. Moretta, L. (1996) Receptors for HLA class-I molecules in human natural killer cells. Annual Review of Immunology, 14, 619.
21. Park, Y., Choi, H., Park, H., Park, S., Yoo, E.K., Kim, D. Sanjeevi, C.B. (2006) Predominance of the group A killer Ig-like receptor haplotypes in Korean patients with T1D. Annals of the New York Academy of Sciences, 1079, 240.
22. Redondo, M.J., Yu, L., Hawa, M., Mackenzie, T., Pyke, D.A., Eisenbarth, G.S. Leslie, R.D.G. (2001) Heterogeneity of type I diabetes: analysis of monozygotic twins in Great Britain and the United States. Diabetologia, 44, 354.
23. Rodacki, M., Svoren, B., Butty, V., Besse, W., Laffel, L., Benoist, C. Mathis, D. (2007) Altered natural killer cells in type 1 diabetic patients. Diabetes, 56, 177.
24. Sanjeevi, C.B., Hagopian, W.A., Landin-Olsson, M., Kockum, I., Woo, W., Palmer, J.P., Lernmark, A. Dahlquist, G. (1998) Association between autoantibody markers and subtypes of DR4 and DR4-DQ in Swedish children with insulin-dependent diabetes reveals closer association of tyrosine pyrophosphatase autoimmunity with DR4 than DQ8. Tissue Antigens, 51, 281.
25. Santin, I., de Nanclares, G.P., Calvo, B., Gaafar, A., Castano, L., Bilbao, J.R. GEPV-N Group (2006) Killer cell immunoglobulin-like receptor (KIR) genes in the Basque population: association study of KIR gene contents with type 1 diabetes mellitus. Human Immunology, 67, 118.
26. Shi, F.D. Luc Van, K. (2006) Reciprocal regulation between natural killer cells and autoreactive T cells. Nature Reviews Immunology, 6, 751.
27. Shtauvere, A., Rumba, I., Dzivite, I. Sanjeevi, C.B. (1998) HLA-DR and DQ gene polymorphism in Latvian patients with insulin-dependent diabetes mellitus. Tissue Antigens, 52, 385.
28. van der Slik, A.R., Koeleman, B.P., Verduijn, W., Bruining, G.J., Roep, B.O. Giphart, M.J. (2003) KIR in type 1 diabetes: disparate distribution of activating and inhibitory natural killer cell receptors in patients versus HLA-matched control subjects. Diabetes, 52, 2639.
29. Svejgaard, A. Ryder, L. (1994) HLA and genetic associations: detecting the strongest association. Tissue Antigens, 43, 18.
30. Tisch, R. McDevitt, H. (1996) Insulin-dependent diabetes mellitus. Cell, 85, 291.
31. Todd, D.J., Forsberg, E.M., Greiner, D.L., Mordes, J.P., Rossini, A.A. Bortell, R. (2004) Deficiencies in gut NK cell number and function precede diabetes onset in BB rats. The Journal of Immunology, 172, 5356.
32. Uhrberg, M., Valiante, N.M., Young, N.T., Lanier, L.L., Phillips, J.H. Parham, P.J. (2001) The repertoire of killer cell Ig-like receptor and CD94:NKG2A receptors in T cells: clones sharing identical αβ TCR rearrangement express highly diverse killer cell Ig-like receptor patterns. Immunology, 166, 3923.
33. Van Autreve, J.E., Koeleman, B.P., Quartier, E., Aminkeng, F., Weets, I., Gorus, F.K. Van der Auwera, B.J. (2006) Belgian Diabetes Registry. MICA is associated with type 1 diabetes in the Belgian population, independent of HLA-DQ. Human Immunology (1-2 94.
34. Vilches, C. Parham, P. (2002) KIR: diverse, rapidly evolving receptors of innate and adaptive immunity. Annual Review of Immunology, 20, 217.
35. Wen, L. Wong, F.S. (2005) How can the innate system influence autoimmunity in type 1 diabetes and other autoimmune disorders. Critical Reviews in Immunology, 25, 225.
36. Yen, J.H., Lin, C.H., Tsai, W.C., Wu, C.C., Ou, T.T., Hu, C.J. Liu, H.W. (2006) Killer cell immunoglobulin-like receptor gene's repertoire in rheumatoid arthritis. Scandinavian Journal of Rheumatology, 35, 124.
37. Zeying, D., Gjertson, D.W., Reed, E.F. Rajalingam, R. (2007) Receptor-ligand analyses define minimal killer cell Ig-like receptor (KIR) in humans. Immunogenetics, 59, 1.