Killer Cell Immunoglobulin-Like Receptor (KIR) Genes in the Basque Population: Association Study of KIR Gene Contents With Type 1 Diabetes Mellitus

Human Immunology

Volumn 67, Issue 1-2, 2006, Pages 118-124

  Santin, Izortze ^a,c   de Nanclares, Guiomar Pérez ^a,c   Calvo, Begoña ^a,c   Gaafar, Ayman ^a,c   Castaño, Luis ^a,b,c   Bilbao, Jose Ramon ^a,b,c  

^a HOSPITAL DE CRUCES   (Spain)

^b UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

^c GEPV N Group: Basque Navarre Pediatrics and Endocrinology Group   (Spain)

Author keywords

Basque population; HLA C; Killer cell immunoglobulin like receptors; type 1 diabetes

Indexed keywords

HLA ANTIGEN; HLA C ANTIGEN; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR;

ARTICLE; CAUCASIAN; COMPARATIVE STUDY; CONTROLLED STUDY; GENE AMPLIFICATION; GENE FREQUENCY; GENE SEQUENCE; GENETIC ASSOCIATION; GENOTYPE; HAPLOTYPE; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; KILLER CELL; POPULATION GENETICS; PRIORITY JOURNAL;

DIABETES MELLITUS, TYPE 1; EPIDEMIOLOGY, MOLECULAR; ETHNIC GROUPS; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HAPLOTYPES; HUMANS; MALE; POPULATION; RECEPTORS, IMMUNOLOGIC; SPAIN;

EID: 33646377175     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.humimm.2006.02.036     Document Type: Article

References (32)

1. Harel-Bellan A., Quillet A., Marchiol C., DeMars R., Tursz T., and Fradelizi D. Natural killer susceptibility of human cells may be regulated by genes in the HLA region on chromosome 6. Proc Natl Acad Sci USA 83 (1986) 5688
2. Moretta A., Tambussi G., Bottino C., Tripodi G., Merli A., Ciccone E., Pantaleo G., and Moretta L. A novel surface antigen expresed by a subset of human CD3-CD16+ natural killer cells. Role in cell activation and regulation of cytolytic function. J Exp Med 171 (1990) 695
3. Rajagopalan S., and Long E.O. Understanding how combinations of HLA and KIR genes influence disease. J Exp Med 201 (2005) 1025
4. Lanier L.L. NK cell receptors. Annu Rev Immunol 16 (1998) 359
5. Martin A.M., Freitas E.M., Witt C.S., and Christiansen F.T. The genomic organization and evolution of natural killer immunoglobulin-like receptor (KIR) gene cluster. Immunogenetics 51 (2000) 268
6. Steffens U., Vyas Y., Dupont B., and Selvakumar A. Nucleotide and amino acid sequence alignment for human killer cell inhibitory receptors (KIR). Tissue Antigens 51 (1998) 398
7. Shilling H.G., Guethlein L.A., Cheng N.W., Gardiner C.M., Rodriguez R., Tyan D., and Parham P. Allelic polymorphism synergizes with variable gene content to individualize human KIR genotype. J Immunol 168 (2002) 2307
8. Yawata M., Yawata N., McQueen K.L., Cheng N.G., Guethlein L.A., Rajalingam R., Shilling H.G., and Parham P. Predominance of group A KIR haplotypes in Japanese associated with diverse NK cell repertoires of KIR expression. Immunogenetics 54 (2002) 543
9. Niokou D., Spyropoulou-Vlachou M., Darlamitsou A., and Stavropoulos-Giokas C. Distribution of killer cell immunoglobulin-like receptors in the Greek population. Hum Immunol 64 (2003) 1167
10. Norman P.J., Stephens H.A., Verity D.H., Chandanayingyong D., and Vaughan R.W. Distribution of natural killer cell immunoglobulin-like receptor sequences in three ethnic groups. Immunogenetics 52 (2001) 195
11. Toneva M., Lepage V., Lafay G., Dulphy N., Busson M., Lester S., Vu-Trien A., Michaylova A., Naumova E., McCluskey J., and Charron D. Genomic diversity of natural killer cell receptor genes in three populations. Tissue antigens 57 (2001) 358
12. Rajalingam R., Krausa P., Shilling H.G., Stein J.B., Balamurugan A., McGinnis M.D., Cheng N.W., Mehra N.K., and Parham P. Distinctive KIR and HLA diversity in a panel of north Indian Hindus. Immunogenetics 53 (2002) 1009
13. Jiang K., Zhu F.M., Lv Q.F., and Yan L.X. Distribution of killer cell immunoglobulin-like receptor genes in the Chinese Han population. Tissue antigens 65 (2005) 556
14. Denis L., Sivula J., Gourraud P.A., Kerdudou N., Chout R., Ricard C., Moisan J.P., Gagne K., Partanen J., and Bignon J.D. Genetic diversity of KIR natural killer cell markers in populations from France, Guadeloupe, Finland, Senegal and Reunion. Tissue Antigens 66 (2005) 267
15. Comas D., Mateu E., Calafell F., Perez-Lezaun A., Bosch E., Martinez-Arias R., and Bertranpetit J. HLA class I and class II DNA typing and the origin of basques. Tissue Antigens 51 (1998) 30
16. Aguirre A., Vicario A., Mazon L.I., Estomba A., Martinez de Pancorbo M., Arrieta Pico V., Perez Elortondo F., and Lostao C.M. Are the Basques a Single and a Unique Population?. Am J Hum Genet 49 (1991) 450
17. Bertranpetit J., and Cavalli-Sforza L.L. A genetic reconstruction of the history of the population of the Iberian Peninsula. Ann Hum Genet 55 (1991) 51
18. Steck A.K., Bugawan T.L., Valdes A.M., Emery L.M., Blair A., Norris J.M., Redondo M.J., Babu S.R., Erlich H.A., Eisenbarth G.S., and Rewers M.J. Association of non-HLA genes with type I diabetes autoimmunity. Diabetes 54 (2005) 2482
19. Pugliese A. Genetics of type 1 Diabetes. Endocrinol Metab Clin N Am 33 (2004) 1
20. Novota P., Kolostova K., Pinterova D., Novak J., Weber P., Treslova L., Kovar J., Andel M., and Cerna M. Association of MHC class I chain related gene-A microsatellite polymorphism with the susceptibility to T1DM and LADA in Czech adult patients. Int J Immunogenet 32 (2005) 273
21. Pirie F.J., Pegoraro R., Motala A.A., Rauff S., Rom L., Govender T., and Esterhuizen T.M. Toll-like receptor 3 gene polymorphisms in South African Blacks with type 1 diabetes. Tissue antigens 66 (2005) 125
22. van der Slik A.R., Koeleman B.P., Verduijn W., Bruining G.J., Roep B.O., and Giphart M.J. KIR in type 1 diabetes. Disparate distribution of activating and inhibitory natural killer cell receptors in patients versus HLA-matched control subjects. Diabetes 52 (2003) 2639
23. Yen J.H., Moore B.E., Nakajima T., Scholl D., Schaid D.J., Weyand C.M., and Goronzy J.J. Major histocompatibility complex class l-recognizing receptors are disease risk gene in rheumatoid arthritis. J Exp Med 193 (2001) 1159
24. Namekawa T., Snyder M.R., Yen J.H., Goehring B.E., Leibson P.J., Weyand C.M., and Goronzy J.J. Killer cell activating receptors function as costimutatory molecules on CD4+CD28null T cells expanded in rheumatoid arthritis. J Immunol 165 (2000) 1138
25. Martin M.P., Nelson G., Lee J.H., Pellet F., Gao X., Wade J., Wilson M.J., Trowsdale J., Gladman D., and Carrington M. Cutting edge: susceptibility to psoriatic arthritis: influence of activating killer Ig-like receptor genes in the absence of specific HLA-C alleles. J Immunol 169 (2002) 2818
26. Moodie S.J., Norman P.J., King A.L., Fraser J.S., Curtis D., Ellis H.J., Vaughan R.W., and Ciclitira P.J. Analysis of candidate genes on chromosome 19 in coeliac disease. an association study of the KIR and LILR gene clusters. Eur J Immunogenet 29 (2002) 287
27. Hsu K.C., Liu X.R., Selvakumar A., Mickelson E., O'Reilly R.J., and Dupont B. Killer Ig-like receptor haplotype analysis by gene content. evidence for genomic diversity with a minimum of six basic framework haplotypes, each with multiple subsets. J Immunol 169 (2002) 5118
28. Selvakumar A., Steffens U., and Dupont B. Polymorphism and domain variability of human killer cell inhibitory receptors. Immunol Rev 155 (1997) 183
29. Uhrberg M., Valiante N.M., Shum B.P., Shilling H.G., Lienert-Weidenbach K., Corliss B., Tyan D., Lanier L.L., and Parham P. Human diversity in killer cell inhibitory receptor genes. Immunity 7 (1997) 753
30. Kakhoo S., Rajalingam R., Shum B.P., Weidenbach K., Flodin L., Muir D.G., Canavez F., Cooper S.L., Valiante N.M., Lanier L.L., and Parham P. Rapid evolution of NK cell receptor systems demonstrated by comparison of chimpazees and humans. Immunity 12 (2000) 687
31. Shilling H., Lienert-Weidenbach K., Valiante N., Uhrberg M., and Parham P. Evidence for recombination as a mechanism for KIR diversification. Immunogenetics 48 (1998) 413
32. Carrington M., and Norman P. The KIR Gene Cluster (2003), National Library of Medicine (US), National Center for Biotechnology Information, Bethesda (MD)