메뉴 건너뛰기




Volumn 3, Issue 4, 2008, Pages 313-318

The conundrum of hyperuricemia, metabolic syndrome, and renal disease

Author keywords

Insulin resistance; Metabolic syndrome; Renal disease; Uric acid

Indexed keywords

URIC ACID;

EID: 55949093135     PISSN: 18280447     EISSN: 19709366     Source Type: Journal    
DOI: 10.1007/s11739-008-0141-3     Document Type: Review
Times cited : (44)

References (50)
  • 1
    • 54949086947 scopus 로고
    • The interpretation of increased blood uric acid in hyertension
    • AM Fishberg 1924 The interpretation of increased blood uric acid in hyertension Arch Int Med 34 503 507
    • (1924) Arch Int Med , vol.34 , pp. 503-507
    • Fishberg, A.M.1
  • 2
    • 0014034942 scopus 로고
    • Epidemiology of gout and hyperuricemia. a long-term population study
    • AP Hall PE Barry TR Dawber 1967 Epidemiology of gout and hyperuricemia. A long-term population study Am J Med 42 27 37
    • (1967) Am J Med , vol.42 , pp. 27-37
    • Hall, A.P.1    Barry, P.E.2    Dawber, T.R.3
  • 4
    • 0037161834 scopus 로고    scopus 로고
    • Molecular identification of a renal urate anion exchanger that regulates blood urate levels
    • A Enomoto H Kimura A Chairoungdua 2002 Molecular identification of a renal urate anion exchanger that regulates blood urate levels Nature 417 447 452
    • (2002) Nature , vol.417 , pp. 447-452
    • Enomoto, A.1    Kimura, H.2    Chairoungdua, A.3
  • 5
    • 0027476664 scopus 로고
    • Uric acid transport in rat renal basolateral membrane vesicles
    • CA Polkowski SM Grassl 1993 Uric acid transport in rat renal basolateral membrane vesicles Biochim Biophys Acta 1146 145 152
    • (1993) Biochim Biophys Acta , vol.1146 , pp. 145-152
    • Polkowski, C.A.1    Grassl, S.M.2
  • 6
    • 12144257103 scopus 로고    scopus 로고
    • Human organic anion transporter MRP4 (ABCC4) is an efflux pump for the purine end metabolite urate with multiple allosteric substrate binding sites
    • RA Van Aubel PH Smeets JJ van den Heuvel 2005 Human organic anion transporter MRP4 (ABCC4) is an efflux pump for the purine end metabolite urate with multiple allosteric substrate binding sites Am J Physiol Renal Physiol 288 F327 F333
    • (2005) Am J Physiol Renal Physiol , vol.288
    • Van Aubel, R.A.1    Smeets, P.H.2    Van Den Heuvel, J.J.3
  • 7
    • 72949151443 scopus 로고
    • Gout, familial hypericaemia, and renal disease
    • H Duncan AS Dixon 1960 Gout, familial hypericaemia, and renal disease Q J Med 29 127 135
    • (1960) Q J Med , vol.29 , pp. 127-135
    • Duncan, H.1    Dixon, A.S.2
  • 9
    • 0019801834 scopus 로고
    • Urate deposits in the renal medulla. Prevalence and associations
    • JW Linnane AF Burry BT Emmerson 1981 Urate deposits in the renal medulla. Prevalence and associations Nephron 29 216 222
    • (1981) Nephron , vol.29 , pp. 216-222
    • Linnane, J.W.1    Burry, A.F.2    Emmerson, B.T.3
  • 10
    • 0030979322 scopus 로고    scopus 로고
    • Predictors of the progression of renal disease in the Modification of Diet in Renal Disease Study
    • LG Hunsicker S Adler A Caggiula 1997 Predictors of the progression of renal disease in the Modification of Diet in Renal Disease Study Kidney Int 51 1908 1919
    • (1997) Kidney Int , vol.51 , pp. 1908-1919
    • Hunsicker, L.G.1    Adler, S.2    Caggiula, A.3
  • 11
    • 34248384541 scopus 로고    scopus 로고
    • Does hyperuricemia affect mortality? a prospective cohort study of Japanese male workers
    • M Tomita S Mizuno H Yamanaka 2000 Does hyperuricemia affect mortality? A prospective cohort study of Japanese male workers J Epidemiol 10 403 409
    • (2000) J Epidemiol , vol.10 , pp. 403-409
    • Tomita, M.1    Mizuno, S.2    Yamanaka, H.3
  • 12
    • 0035207070 scopus 로고    scopus 로고
    • Significance of hyperuricemia on the early detection of renal failure in a cohort of screened subjects
    • K Iseki S Oshiro M Tozawa 2001 Significance of hyperuricemia on the early detection of renal failure in a cohort of screened subjects Hypertens Res 24 691 697
    • (2001) Hypertens Res , vol.24 , pp. 691-697
    • Iseki, K.1    Oshiro, S.2    Tozawa, M.3
  • 13
    • 0035089152 scopus 로고    scopus 로고
    • Serum uric acid and renal prognosis in patients with IgA nephropathy
    • I Ohno T Hosoya H Gomi 2001 Serum uric acid and renal prognosis in patients with IgA nephropathy Nephron 87 333 339
    • (2001) Nephron , vol.87 , pp. 333-339
    • Ohno, I.1    Hosoya, T.2    Gomi, H.3
  • 14
    • 23744490953 scopus 로고    scopus 로고
    • Correlation of uric acid and urinary albumin excretion rate in patients with type 2 diabetes mellitus in Taiwan
    • CH Tseng 2005 Correlation of uric acid and urinary albumin excretion rate in patients with type 2 diabetes mellitus in Taiwan Kidney Int 68 796 801
    • (2005) Kidney Int , vol.68 , pp. 796-801
    • Tseng, C.H.1
  • 15
    • 29244447160 scopus 로고    scopus 로고
    • Use of allopurinol in slowing the progression of renal disease through its ability to lower serum uric acid level
    • Y Siu K Leung M Tong 2006 Use of allopurinol in slowing the progression of renal disease through its ability to lower serum uric acid level Am J Kidney Dis 47 51 59
    • (2006) Am J Kidney Dis , vol.47 , pp. 51-59
    • Siu, Y.1    Leung, K.2    Tong, M.3
  • 16
    • 34748901886 scopus 로고    scopus 로고
    • The effect of mild hyperuricemia on urinary transforming growth factor beta and the progression of chronic kidney disease
    • KM Talaat AR El-Sheikh 2007 The effect of mild hyperuricemia on urinary transforming growth factor beta and the progression of chronic kidney disease Am J Nephrol 27 435 440
    • (2007) Am J Nephrol , vol.27 , pp. 435-440
    • Talaat, K.M.1    El-Sheikh, A.R.2
  • 17
    • 0344373794 scopus 로고    scopus 로고
    • Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic: The antihypertensive, lipid-lowering treatment to prevent heart attack trial (ALLHAT)
    • Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic: the antihypertensive, lipid-lowering treatment to prevent heart attack trial (ALLHAT). Jama 2002; 288:2981-2997
    • (2002) Jama , vol.288 , pp. 2981-2997
  • 18
    • 0242654867 scopus 로고    scopus 로고
    • Effects of different blood-pressure-lowering regimens on major cardiovascular events: Results of prospectively-designed overviews of randomised trials
    • F Turnbull 2003 Effects of different blood-pressure-lowering regimens on major cardiovascular events: results of prospectively-designed overviews of randomised trials Lancet 362 1527 1535
    • (2003) Lancet , vol.362 , pp. 1527-1535
    • Turnbull, F.1
  • 19
    • 0026012922 scopus 로고
    • Risks and benefits in the trial of the European Working Party on High Blood Pressure in the Elderly
    • A Fletcher A Amery W Birkenhager 1991 Risks and benefits in the trial of the European Working Party on High Blood Pressure in the Elderly J Hypertens 9 225 230
    • (1991) J Hypertens , vol.9 , pp. 225-230
    • Fletcher, A.1    Amery, A.2    Birkenhager, W.3
  • 20
    • 0032513534 scopus 로고    scopus 로고
    • Influence of long-term, low-dose, diuretic-based, antihypertensive therapy on glucose, lipid, uric acid, and potassium levels in older men and women with isolated systolic hypertension: The systolic hypertension in the Elderly Program. SHEP Cooperative Research Group
    • PJ Savage SL Pressel JD Curb 1998 Influence of long-term, low-dose, diuretic-based, antihypertensive therapy on glucose, lipid, uric acid, and potassium levels in older men and women with isolated systolic hypertension: the systolic hypertension in the Elderly Program. SHEP Cooperative Research Group Arch Intern Med 158 741 751
    • (1998) Arch Intern Med , vol.158 , pp. 741-751
    • Savage, P.J.1    Pressel, S.L.2    Curb, J.D.3
  • 21
    • 0034729993 scopus 로고    scopus 로고
    • Morbidity and mortality in patients randomised to double-blind treatment with a long-acting calcium-channel blocker or diuretic in the International Nifedipine GITS study: Intervention as a Goal in Hypertension Treatment (INSIGHT)
    • MJ Brown CR Palmer A Castaigne 2000 Morbidity and mortality in patients randomised to double-blind treatment with a long-acting calcium-channel blocker or diuretic in the International Nifedipine GITS study: Intervention as a Goal in Hypertension Treatment (INSIGHT) Lancet 356 366 372
    • (2000) Lancet , vol.356 , pp. 366-372
    • Brown, M.J.1    Palmer, C.R.2    Castaigne, A.3
  • 22
    • 0033851739 scopus 로고    scopus 로고
    • Serum uric acid, diuretic treatment and risk of cardiovascular events in the Systolic Hypertension in the Elderly Program (SHEP)
    • LV Franse M Pahor M Di Bari 2000 Serum uric acid, diuretic treatment and risk of cardiovascular events in the Systolic Hypertension in the Elderly Program (SHEP) J Hypertens 18 1149 1154
    • (2000) J Hypertens , vol.18 , pp. 1149-1154
    • Franse, L.V.1    Pahor, M.2    Di Bari, M.3
  • 23
    • 0042334471 scopus 로고    scopus 로고
    • Hyperuricemia in childhood primary hypertension
    • DI Feig RJ Johnson 2003 Hyperuricemia in childhood primary hypertension Hypertension 42 247 252
    • (2003) Hypertension , vol.42 , pp. 247-252
    • Feig, D.I.1    Johnson, R.J.2
  • 24
    • 33646376660 scopus 로고    scopus 로고
    • Uric acid and endothelial dysfunction in essential hypertension
    • C Zoccali R Maio F Mallamaci 2006 Uric acid and endothelial dysfunction in essential hypertension J Am Soc Nephrol 17 1466 1471
    • (2006) J Am Soc Nephrol , vol.17 , pp. 1466-1471
    • Zoccali, C.1    Maio, R.2    Mallamaci, F.3
  • 25
    • 0037024270 scopus 로고    scopus 로고
    • Effects of xanthine oxidase inhibition with allopurinol on endothelial function and peripheral blood flow in hyperuricemic patients with chronic heart failure: Results from 2 placebo-controlled studies
    • W Doehner N Schoene M Rauchhaus 2002 Effects of xanthine oxidase inhibition with allopurinol on endothelial function and peripheral blood flow in hyperuricemic patients with chronic heart failure: results from 2 placebo-controlled studies Circulation 105 2619 2624
    • (2002) Circulation , vol.105 , pp. 2619-2624
    • Doehner, W.1    Schoene, N.2    Rauchhaus, M.3
  • 26
    • 33845447368 scopus 로고    scopus 로고
    • High-dose allopurinol improves endothelial function by profoundly reducing vascular oxidative stress and not by lowering uric acid
    • J George E Carr J Davies 2006 High-dose allopurinol improves endothelial function by profoundly reducing vascular oxidative stress and not by lowering uric acid Circulation 114 2508 2516
    • (2006) Circulation , vol.114 , pp. 2508-2516
    • George, J.1    Carr, E.2    Davies, J.3
  • 27
    • 4644279733 scopus 로고    scopus 로고
    • Increasing prevalence of the metabolic syndrome among U.S. adults
    • ES Ford WH Giles AH Mokdad 2004 Increasing prevalence of the metabolic syndrome among U.S. adults Diabetes Care 27 2444 2449
    • (2004) Diabetes Care , vol.27 , pp. 2444-2449
    • Ford, E.S.1    Giles, W.H.2    Mokdad, A.H.3
  • 28
    • 0026325211 scopus 로고
    • Relationship between resistance to insulin-mediated glucose uptake, urinary uric acid clearance, and plasma uric acid concentration
    • F Facchini YD Chen CB Hollenbeck 1991 Relationship between resistance to insulin-mediated glucose uptake, urinary uric acid clearance, and plasma uric acid concentration Jama 266 3008 3011
    • (1991) Jama , vol.266 , pp. 3008-3011
    • Facchini, F.1    Chen, Y.D.2    Hollenbeck, C.B.3
  • 29
    • 0742266631 scopus 로고    scopus 로고
    • The metabolic syndrome and chronic kidney disease in U.S. adults
    • J Chen P Muntner LL Hamm 2004 The metabolic syndrome and chronic kidney disease in U.S. adults Ann Intern Med 140 167 174
    • (2004) Ann Intern Med , vol.140 , pp. 167-174
    • Chen, J.1    Muntner, P.2    Hamm, L.L.3
  • 30
    • 15944406797 scopus 로고    scopus 로고
    • Insulin resistance in patients with chronic kidney disease
    • S Kobayashi K Maesato H Moriya 2005 Insulin resistance in patients with chronic kidney disease Am J Kidney Dis 45 275 280
    • (2005) Am J Kidney Dis , vol.45 , pp. 275-280
    • Kobayashi, S.1    Maesato, K.2    Moriya, H.3
  • 31
    • 21344446701 scopus 로고    scopus 로고
    • Renal insulin resistance syndrome, adiponectin and cardiovascular events in patients with kidney disease: The mild and moderate kidney disease study
    • B Becker F Kronenberg JT Kielstein 2005 Renal insulin resistance syndrome, adiponectin and cardiovascular events in patients with kidney disease: the mild and moderate kidney disease study J Am Soc Nephrol 16 1091 1098
    • (2005) J Am Soc Nephrol , vol.16 , pp. 1091-1098
    • Becker, B.1    Kronenberg, F.2    Kielstein, J.T.3
  • 33
    • 0029760594 scopus 로고    scopus 로고
    • Effect of insulin on renal sodium and uric acid handling in essential hypertension
    • E Muscelli A Natali S Bianchi 1996 Effect of insulin on renal sodium and uric acid handling in essential hypertension Am J Hypertens 9 746 752
    • (1996) Am J Hypertens , vol.9 , pp. 746-752
    • Muscelli, E.1    Natali, A.2    Bianchi, S.3
  • 34
    • 33646338312 scopus 로고    scopus 로고
    • Hypothesis:fructose-induced hyperuricemia as a causal mechanism for the epidemic of the metabolic syndrome
    • T Nakagawa KR Tuttle RA Short 2005 Hypothesis:fructose-induced hyperuricemia as a causal mechanism for the epidemic of the metabolic syndrome Nat Clin Pract Nephorl 1 80 86
    • (2005) Nat Clin Pract Nephorl , vol.1 , pp. 80-86
    • Nakagawa, T.1    Tuttle, K.R.2    Short, R.A.3
  • 35
    • 0035723995 scopus 로고    scopus 로고
    • Elevated uric acid increases blood pressure in the rat by a novel crystal-independent mechanism
    • M Mazzali J Hughes YG Kim 2001 Elevated uric acid increases blood pressure in the rat by a novel crystal-independent mechanism Hypertension 38 1101 1106
    • (2001) Hypertension , vol.38 , pp. 1101-1106
    • Mazzali, M.1    Hughes, J.2    Kim, Y.G.3
  • 36
    • 0037210124 scopus 로고    scopus 로고
    • Hyperuricemia causes glomerular hypertrophy in the rat
    • T Nakagawa M Mazzali DH Kang 2003 Hyperuricemia causes glomerular hypertrophy in the rat Am J Nephrol 23 2 7
    • (2003) Am J Nephrol , vol.23 , pp. 2-7
    • Nakagawa, T.1    Mazzali, M.2    Kang, D.H.3
  • 37
    • 10944243094 scopus 로고    scopus 로고
    • Mild hyperuricemia induces vasoconstriction and maintains glomerular hypertension in normal and remnant kidney rats
    • LG Sanchez-Lozada E Tapia J Santamaria 2005 Mild hyperuricemia induces vasoconstriction and maintains glomerular hypertension in normal and remnant kidney rats Kidney Int 67 237 247
    • (2005) Kidney Int , vol.67 , pp. 237-247
    • Sanchez-Lozada, L.G.1    Tapia, E.2    Santamaria, J.3
  • 38
    • 0036083844 scopus 로고    scopus 로고
    • Hyperuricemia induces a primary renal arteriolopathy in rats by a blood pressure-independent mechanism
    • M Mazzali J Kanellis L Han 2002 Hyperuricemia induces a primary renal arteriolopathy in rats by a blood pressure-independent mechanism Am J Physiol Renal Physiol 282 F991 F997
    • (2002) Am J Physiol Renal Physiol , vol.282
    • Mazzali, M.1    Kanellis, J.2    Han, L.3
  • 39
    • 0036892614 scopus 로고    scopus 로고
    • A role for uric acid in the progression of renal disease
    • DH Kang T Nakagawa L Feng 2002 A role for uric acid in the progression of renal disease J Am Soc Nephrol 13 2888 2897
    • (2002) J Am Soc Nephrol , vol.13 , pp. 2888-2897
    • Kang, D.H.1    Nakagawa, T.2    Feng, L.3
  • 40
    • 0035870661 scopus 로고    scopus 로고
    • Hyperuricemia exacerbates chronic cyclosporine nephropathy
    • M Mazzali YG Kim S Suga 2001 Hyperuricemia exacerbates chronic cyclosporine nephropathy Transplantation 71 900 905
    • (2001) Transplantation , vol.71 , pp. 900-905
    • Mazzali, M.1    Kim, Y.G.2    Suga, S.3
  • 41
    • 0034600288 scopus 로고    scopus 로고
    • Circadian relationship of serum uric acid and nitric oxide
    • EL Kanabrocki JL Third MD Ryan 2000 Circadian relationship of serum uric acid and nitric oxide Jama 283 2240 2241
    • (2000) Jama , vol.283 , pp. 2240-2241
    • Kanabrocki, E.L.1    Third, J.L.2    Ryan, M.D.3
  • 42
    • 3042769305 scopus 로고    scopus 로고
    • Hypothesis: Uric acid, nephron number, and the pathogenesis of essential hypertension
    • DI Feig T Nakagawa SA Karumanchi 2004 Hypothesis: Uric acid, nephron number, and the pathogenesis of essential hypertension Kidney Int 66 281 287
    • (2004) Kidney Int , vol.66 , pp. 281-287
    • Feig, D.I.1    Nakagawa, T.2    Karumanchi, S.A.3
  • 43
    • 34547733397 scopus 로고    scopus 로고
    • Adverse effects of the classical antioxidant uric acid in adipocytes: NADPH oxidase-mediated oxidative/nitrosative stress
    • YY Sautin T Nakagawa S Zharikov 2007 Adverse effects of the classical antioxidant uric acid in adipocytes: NADPH oxidase-mediated oxidative/ nitrosative stress Am J Physiol Cell Physiol 293 C584 C596
    • (2007) Am J Physiol Cell Physiol , vol.293
    • Sautin, Y.Y.1    Nakagawa, T.2    Zharikov, S.3
  • 44
    • 33845533406 scopus 로고    scopus 로고
    • Uric acid restores endothelial function in patients with type 1 diabetes and regular smokers
    • WS Waring JA McKnight DJ Webb 2006 Uric acid restores endothelial function in patients with type 1 diabetes and regular smokers Diabetes 55 3127 3132
    • (2006) Diabetes , vol.55 , pp. 3127-3132
    • Waring, W.S.1    McKnight, J.A.2    Webb, D.J.3
  • 45
    • 0034888485 scopus 로고    scopus 로고
    • Systemic uric acid administration increases serum antioxidant capacity in healthy volunteers
    • WS Waring DJ Webb SR Maxwell 2001 Systemic uric acid administration increases serum antioxidant capacity in healthy volunteers J Cardiovasc Pharmacol 38 365 371
    • (2001) J Cardiovasc Pharmacol , vol.38 , pp. 365-371
    • Waring, W.S.1    Webb, D.J.2    Maxwell, S.R.3
  • 46
    • 0029908148 scopus 로고    scopus 로고
    • Protection against peroxynitrite-dependent tyrosine nitration and alpha 1-antiproteinase inactivation by ascorbic acid. a comparison with other biological antioxidants
    • M Whiteman B Halliwell 1996 Protection against peroxynitrite-dependent tyrosine nitration and alpha 1-antiproteinase inactivation by ascorbic acid. A comparison with other biological antioxidants Free Radic Res 25 275 283
    • (1996) Free Radic Res , vol.25 , pp. 275-283
    • Whiteman, M.1    Halliwell, B.2
  • 47
    • 0032544734 scopus 로고    scopus 로고
    • Nitrosation of uric acid by peroxynitrite. Formation of a vasoactive nitric oxide donor
    • KA Skinner CR White R Patel 1998 Nitrosation of uric acid by peroxynitrite. Formation of a vasoactive nitric oxide donor J Biol Chem 273 24491 24497
    • (1998) J Biol Chem , vol.273 , pp. 24491-24497
    • Skinner, K.A.1    White, C.R.2    Patel, R.3
  • 48
    • 0017867253 scopus 로고
    • Serum uric acid and the renin-angiotensin system in hypertension
    • I Saito T Saruta K Kondo 1978 Serum uric acid and the renin-angiotensin system in hypertension J Am Geriatr Soc 26 241 247
    • (1978) J Am Geriatr Soc , vol.26 , pp. 241-247
    • Saito, I.1    Saruta, T.2    Kondo, K.3
  • 49
    • 33846194270 scopus 로고    scopus 로고
    • Effect of elevated serum uric acid on cisplatin-induced acute renal failure
    • CA Roncal W Mu B Croker 2007 Effect of elevated serum uric acid on cisplatin-induced acute renal failure Am J Physiol Renal Physiol 292 F116 122
    • (2007) Am J Physiol Renal Physiol , vol.292 , pp. 116-122
    • Roncal, C.A.1    Mu, W.2    Croker, B.3
  • 50
    • 33846211514 scopus 로고    scopus 로고
    • Fructose-induced metabolic syndrome is associated with glomerular hypertension and renal microvascular damage in rats.
    • 1
    • LG Sanchez-Lozada E Tapia A Jimenez 2006 Fructose-induced metabolic syndrome is associated with glomerular hypertension and renal microvascular damage in rats. Am J Physiol Renal Physiol 292 1 F423 F429
    • (2006) Am J Physiol Renal Physiol , vol.292
    • Sanchez-Lozada, L.G.1    Tapia, E.2    Jimenez, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.