Cocaine disinhibits dopamine neurons in the ventral tegmental area via use-dependent blockade of GABA neuron voltage-sensitive sodium channels

European Journal of Neuroscience

Volumn 28, Issue 10, 2008, Pages 2028-2040

  Steffensen, Scott C ^a   Taylor, Seth R ^a   Horton, Malia L ^a   Barber, Elise N ^a   Lyle, Laura T ^a   Stobbs, Sarah H ^a   Allison, David W ^a  

^a BRIGHAM YOUNG UNIVERSITY   (United States)

Author keywords

Cocaine; Dopamine; GABA; Sodium current; Ventral tegmental area

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; COCAINE; DOPAMINE; DOPAMINE 2 RECEPTOR; DOPAMINE 3 RECEPTOR; DOPAMINE RECEPTOR BLOCKING AGENT; DOPAMINE TRANSPORTER; ETICLOPRIDE; LIDOCAINE; METHAMPHETAMINE; TETRODOTOXIN; VOLTAGE GATED SODIUM CHANNEL;

4 AMINOBUTYRIC ACID RELEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; CAPSULA INTERNA; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; IC 50; IN VITRO STUDY; IN VIVO STUDY; MALE; MICROELECTROPHORESIS; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR BLOCKING; SODIUM CURRENT; VENTRAL TEGMENTUM;

ACTION POTENTIALS; ANIMALS; COCAINE; COCAINE-RELATED DISORDERS; DOPAMINE; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; DOPAMINE UPTAKE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; GAMMA-AMINOBUTYRIC ACID; INHIBITORY POSTSYNAPTIC POTENTIALS; MALE; METHAMPHETAMINE; NEURAL INHIBITION; NEURONS; RATS; RATS, WISTAR; RECEPTORS, DOPAMINE D2; REWARD; SODIUM CHANNEL BLOCKERS; SODIUM CHANNELS; SYNAPTIC TRANSMISSION; VENTRAL TEGMENTAL AREA;

EID: 55949092307     PISSN: 0953816X     EISSN: 14609568     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2008.06479.x     Document Type: Article

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