Cyclization via carbolithiation of α-amino alkyllithium reagents

Organic Letters

Volumn 10, Issue 18, 2008, Pages 4017-4020

  Bahde, Robert J ^a   Rychnovsky, Scott D ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINE; CARBON; DYES, REAGENTS, INDICATORS, MARKERS AND BUFFERS; LITHIUM;

ARTICLE; CHEMISTRY; CYCLIZATION; OXIDATION REDUCTION REACTION;

AMINES; CARBON; CYCLIZATION; INDICATORS AND REAGENTS; LITHIUM; OXIDATION-REDUCTION;

EID: 55949088005     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol801523r     Document Type: Article

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53. The relative energy between the two transition states in Figure 1 is unreasonably large, but the actual values are unlikely to be very accurate because of the complete neglect of solvation in these calculations.