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Volumn 3, Issue 4, 2008, Pages 383-391

Evolution and function of the p35 family of apoptosis inhibitors

Author keywords

Apoptosis; Baculovirus; Caspase; Entomopoxvirus; p33; p35; p49

Indexed keywords

CASPASE; CASPASE INHIBITOR; PROTEIN P33; PROTEIN P35; PROTEIN P35 INHIBITOR; PROTEIN P49; PROTEINASE INHIBITOR; UNCLASSIFIED DRUG; VIRUS PROTEIN;

EID: 55849150962     PISSN: 17460794     EISSN: None     Source Type: Journal    
DOI: 10.2217/17460794.3.4.383     Document Type: Review
Times cited : (6)

References (44)
  • 1
    • 8444220527 scopus 로고    scopus 로고
    • Molecular mechanisms of caspase regulation during apoptosis
    • Riedl SJ, Shi Y: Molecular mechanisms of caspase regulation during apoptosis. Nat. Rev. Mol. Cell Biol. 5, 897-907 (2004).
    • (2004) Nat. Rev. Mol. Cell Biol , vol.5 , pp. 897-907
    • Riedl, S.J.1    Shi, Y.2
  • 2
    • 19444386896 scopus 로고    scopus 로고
    • Apoptosis in Drosophila: Neither fish nor fowl (nor man, nor worm)
    • Kornbluth S, White K: Apoptosis in Drosophila: neither fish nor fowl (nor man, nor worm). J. Cell. Sci. 118, 1779-1787 (2005).
    • (2005) J. Cell. Sci , vol.118 , pp. 1779-1787
    • Kornbluth, S.1    White, K.2
  • 4
    • 0023204535 scopus 로고
    • Divergent transcription of early 35- and 94-kilodalton protein genes encoded by the HindIII K genome fragment of the baculovirus Autographa californica nuclear Polyhedrosis virus
    • Friesen PD, Miller LK: Divergent transcription of early 35- and 94-kilodalton protein genes encoded by the HindIII K genome fragment of the baculovirus Autographa californica nuclear Polyhedrosis virus. J. Virol. 61, 2264-2272 (1987).
    • (1987) J. Virol , vol.61 , pp. 2264-2272
    • Friesen, P.D.1    Miller, L.K.2
  • 5
    • 0026344133 scopus 로고
    • Prevention of apoptosis by a baculovirus gene during infection of insect cells
    • Clem RJ, Fechheimer M, Miller LK: Prevention of apoptosis by a baculovirus gene during infection of insect cells. Science 254, 1388-1390 (1991).
    • (1991) Science , vol.254 , pp. 1388-1390
    • Clem, R.J.1    Fechheimer, M.2    Miller, L.K.3
  • 6
    • 0027215907 scopus 로고
    • Apoptosis reduces both the in vitro replication and the in vivo infectivity of a baculovirus
    • Clem RJ, Miller LK: Apoptosis reduces both the in vitro replication and the in vivo infectivity of a baculovirus. J. Virol. 67, 3730-3738 (1993).
    • (1993) J. Virol , vol.67 , pp. 3730-3738
    • Clem, R.J.1    Miller, L.K.2
  • 7
    • 0028024561 scopus 로고
    • Influence of infection route on the infectivity of baculovirus mutants lacking the apoptosls-inhibiting gene p35 and the adjacent gene p94
    • Clem RJ, Robson M, Miller LK: Influence of infection route on the infectivity of baculovirus mutants lacking the apoptosls-inhibiting gene p35 and the adjacent gene p94. J. Virol. 68, 6759-6762 (1994).
    • (1994) J. Virol , vol.68 , pp. 6759-6762
    • Clem, R.J.1    Robson, M.2    Miller, L.K.3
  • 8
    • 0037303420 scopus 로고    scopus 로고
    • In vivo induction of apoptosis correlating with reduced infectivity during baculovirus infection
    • Clarke TE, Clem RJ: In vivo induction of apoptosis correlating with reduced infectivity during baculovirus infection. J. Virol. 77, 2227-2232 (2003).
    • (2003) J. Virol , vol.77 , pp. 2227-2232
    • Clarke, T.E.1    Clem, R.J.2
  • 9
    • 0028817947 scopus 로고
    • Inhibition of ICE family proteases by baculovirus antiapoptotic protein p35
    • Bump NJ, Hackett M, Hugunin M et al.: Inhibition of ICE family proteases by baculovirus antiapoptotic protein p35. Science 269, 1885-1888 (1995).
    • (1995) Science , vol.269 , pp. 1885-1888
    • Bump, N.J.1    Hackett, M.2    Hugunin, M.3
  • 10
    • 0345654358 scopus 로고    scopus 로고
    • Crystal structure of baculovirus p35: Role of a novel reactive site loop in apoptotic caspase inhibition
    • Fisher AJ, de la Cruz W, Zoog SJ, Schneider CL, Friesen PD: Crystal structure of baculovirus p35: role of a novel reactive site loop in apoptotic caspase inhibition. EMBO J. 18, 2031-2039 (1999).
    • (1999) EMBO J , vol.18 , pp. 2031-2039
    • Fisher, A.J.1    de la Cruz, W.2    Zoog, S.J.3    Schneider, C.L.4    Friesen, P.D.5
  • 11
    • 0035932465 scopus 로고    scopus 로고
    • Covalent inhibition revealed by the crystal structure of the caspase-8/p35 complex
    • Xu G, Cirilli M, Huang Y, Rich RL, Myszka DG, Wu H: Covalent inhibition revealed by the crystal structure of the caspase-8/p35 complex. Nature 410, 494-497 (2001).
    • (2001) Nature , vol.410 , pp. 494-497
    • Xu, G.1    Cirilli, M.2    Huang, Y.3    Rich, R.L.4    Myszka, D.G.5    Wu, H.6
  • 12
    • 0036008513 scopus 로고    scopus 로고
    • Crystallization and low-resolution structure of an effector-caspase/p35 complex: Similarities and differences to an initiator-caspase/p35 complex
    • Eddins MJ, Lemongello D, Friesen PD, Fisher AJ: Crystallization and low-resolution structure of an effector-caspase/p35 complex: similarities and differences to an initiator-caspase/p35 complex. Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. D58, 299-302 (2002).
    • (2002) Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun , vol.D58 , pp. 299-302
    • Eddins, M.J.1    Lemongello, D.2    Friesen, P.D.3    Fisher, A.J.4
  • 13
    • 35348921703 scopus 로고    scopus 로고
    • Baculoviruses and apoptosis: A diversity of genes and responses
    • Clem RJ: Baculoviruses and apoptosis: a diversity of genes and responses. Curr. Drug Targets 8, 1069-1074 (2007).
    • (2007) Curr. Drug Targets , vol.8 , pp. 1069-1074
    • Clem, R.J.1
  • 14
    • 33846357368 scopus 로고    scopus 로고
    • Identification and functional characterization of AMVp33, a novel homolog of the baculovirus caspase inhibitor p35 found in Amsacta moorei entomopoxvirus
    • Means JC, Penabaz T, Clem RJ: Identification and functional characterization of AMVp33, a novel homolog of the baculovirus caspase inhibitor p35 found in Amsacta moorei entomopoxvirus. Virology 358, 436-447 (2007).
    • (2007) Virology , vol.358 , pp. 436-447
    • Means, J.C.1    Penabaz, T.2    Clem, R.J.3
  • 15
    • 0031021919 scopus 로고    scopus 로고
    • Spodoptera frugiperda caspase-1, a novel insect death protease that cleaves the nuclear immunophilin FKBP46, is the target of the baculovirus antiapoptotic protein p35
    • Ahmad M, Srinivasula S, Wang L, Litwack G, Fernandes-Alnemri T, Alnemri E: Spodoptera frugiperda caspase-1, a novel insect death protease that cleaves the nuclear immunophilin FKBP46, is the target of the baculovirus antiapoptotic protein p35. J. Biol. Chem. 272, 1421-1424 (1997).
    • (1997) J. Biol. Chem , vol.272 , pp. 1421-1424
    • Ahmad, M.1    Srinivasula, S.2    Wang, L.3    Litwack, G.4    Fernandes-Alnemri, T.5    Alnemri, E.6
  • 16
    • 0034651987 scopus 로고    scopus 로고
    • The Drosophila caspase DRONC is regulated by DIAP1
    • Meier P, Silke J, Leevers SJ, Even GI: The Drosophila caspase DRONC is regulated by DIAP1. EMBO J. 19, 598-611 (2000).
    • (2000) EMBO J , vol.19 , pp. 598-611
    • Meier, P.1    Silke, J.2    Leevers, S.J.3    Even, G.I.4
  • 17
    • 0034609958 scopus 로고    scopus 로고
    • Baculovirus p35 protein does not inhibit caspase-9 in a cell-free system of apoptosis
    • Vier J, Furmann C, Hacker G: Baculovirus p35 protein does not inhibit caspase-9 in a cell-free system of apoptosis. Biochem. Biophys. Res. Comm. 276, 855-861 (2000).
    • (2000) Biochem. Biophys. Res. Comm , vol.276 , pp. 855-861
    • Vier, J.1    Furmann, C.2    Hacker, G.3
  • 18
    • 85047278700 scopus 로고    scopus 로고
    • Baculovirus apoptotic suppressor p49 is a substrate inhibitor of initiator caspaces resistant to p35 in vitro
    • Zoog SJ, Schiller JJ, Wetter JA, Chejanovsky N, Friesen PD: Baculovirus apoptotic suppressor p49 is a substrate inhibitor of initiator caspaces resistant to p35 in vitro. EMBO J. 21, 5130-5140 (2002).
    • (2002) EMBO J , vol.21 , pp. 5130-5140
    • Zoog, S.J.1    Schiller, J.J.2    Wetter, J.A.3    Chejanovsky, N.4    Friesen, P.D.5
  • 19
    • 0028271740 scopus 로고
    • Baculovirus p35 prevents developmentally programmed cell death and rescues a ced-9 mutant in the nematode Caenorhabditis elegans
    • Sugimoto A, Friesen PD, Rothman JH: Baculovirus p35 prevents developmentally programmed cell death and rescues a ced-9 mutant in the nematode Caenorhabditis elegans. EMBO J. 13, 2023-2028 (1994).
    • (1994) EMBO J , vol.13 , pp. 2023-2028
    • Sugimoto, A.1    Friesen, P.D.2    Rothman, J.H.3
  • 20
    • 0028141705 scopus 로고
    • Expression of baculovirus p35 prevents cell death in Drosophila
    • Hay BA, Wolff T, Rubin GM: Expression of baculovirus p35 prevents cell death in Drosophila. Development 120, 2121-2129 (1994).
    • (1994) Development , vol.120 , pp. 2121-2129
    • Hay, B.A.1    Wolff, T.2    Rubin, G.M.3
  • 21
    • 0027430789 scopus 로고
    • Expression of the baculovirus p35 gene inhibits mammalian neural cell death
    • Rabizadeh S, LaCount DJ, Friesen PD, Bredesen DE: Expression of the baculovirus p35 gene inhibits mammalian neural cell death. J. Neurochem. 61, 2318-2321 (1993).
    • (1993) J. Neurochem , vol.61 , pp. 2318-2321
    • Rabizadeh, S.1    LaCount, D.J.2    Friesen, P.D.3    Bredesen, D.E.4
  • 22
    • 33644502594 scopus 로고    scopus 로고
    • Dendritic cell apoptosis in the maintenance of immune tolerance
    • Chen M, Wang YH, Wang Y et al.: Dendritic cell apoptosis in the maintenance of immune tolerance. Science 311, 1160-1164 (2006).
    • (2006) Science , vol.311 , pp. 1160-1164
    • Chen, M.1    Wang, Y.H.2    Wang, Y.3
  • 23
    • 0036209237 scopus 로고    scopus 로고
    • Commitment to apoptosis induced by tumour necrosis factor-α is dependent on caspase activity
    • Hedge VL, Williams GT: Commitment to apoptosis induced by tumour necrosis factor-α is dependent on caspase activity. Apoptosis 7, 123-132 (2002).
    • (2002) Apoptosis , vol.7 , pp. 123-132
    • Hedge, V.L.1    Williams, G.T.2
  • 24
    • 0029793621 scopus 로고    scopus 로고
    • Apoptotic suppression by baculovirus p35 involves cleavage by and inhibition of a virus-induced CED-3/ICE-like protease
    • Bertin J, Mendrysa SM, LaCount DJ et al.: Apoptotic suppression by baculovirus p35 involves cleavage by and inhibition of a virus-induced CED-3/ICE-like protease. J. Virol. 70, 6251-6259 (1996).
    • (1996) J. Virol , vol.70 , pp. 6251-6259
    • Bertin, J.1    Mendrysa, S.M.2    LaCount, D.J.3
  • 25
    • 0033543616 scopus 로고    scopus 로고
    • Caspase inhibition by baculovirus p35 requires interaction between the reactive site loop and the β-sheet core
    • Zoog SJ, Bertin J, Friesen PD: Caspase inhibition by baculovirus p35 requires interaction between the reactive site loop and the β-sheet core. J. Biol. Chem. 274, 25995-26002 (1999).
    • (1999) J. Biol. Chem , vol.274 , pp. 25995-26002
    • Zoog, S.J.1    Bertin, J.2    Friesen, P.D.3
  • 26
    • 32844468771 scopus 로고    scopus 로고
    • Native chemical ligation in covalent caspase inhibition by p35
    • Lu M, Min T, Eliezer D, Wu H: Native chemical ligation in covalent caspase inhibition by p35. Chem. Biol. 13, 117-122 (2006).
    • (2006) Chem. Biol , vol.13 , pp. 117-122
    • Lu, M.1    Min, T.2    Eliezer, D.3    Wu, H.4
  • 27
    • 0027397409 scopus 로고
    • Identification and characterization of the p35 gene of Bombyx mori nuclear polyhedrosis virus that prevents virus-induced apoptosis
    • Kamita SG, Majima K, Maeda S: Identification and characterization of the p35 gene of Bombyx mori nuclear polyhedrosis virus that prevents virus-induced apoptosis. J. Virol. 67, 455-463 (1993).
    • (1993) J. Virol , vol.67 , pp. 455-463
    • Kamita, S.G.1    Majima, K.2    Maeda, S.3
  • 28
    • 0032079656 scopus 로고    scopus 로고
    • Homologous p35 proteins of baculoviruses show distinctive anti-apoptotic activities which correlate with the apoptosis-inducing activity of each virus
    • Morishima N, Okano K, Shibata T, Maeda S: Homologous p35 proteins of baculoviruses show distinctive anti-apoptotic activities which correlate with the apoptosis-inducing activity of each virus. FEBS Lett. 427, 144-148(1998).
    • (1998) FEBS Lett , vol.427 , pp. 144-148
    • Morishima, N.1    Okano, K.2    Shibata, T.3    Maeda, S.4
  • 29
    • 0032933847 scopus 로고    scopus 로고
    • Isolation of an apoptosis suppressor gene of the Spodoptera littoralis nucleopolyhedrovirus
    • Du Q, Lehavi D, Faktor O, Qi Y, Chejanovsky N: Isolation of an apoptosis suppressor gene of the Spodoptera littoralis nucleopolyhedrovirus. J. Virol. 73, 1278-1285 (1999).
    • (1999) J. Virol , vol.73 , pp. 1278-1285
    • Du, Q.1    Lehavi, D.2    Faktor, O.3    Qi, Y.4    Chejanovsky, N.5
  • 30
    • 12244288291 scopus 로고    scopus 로고
    • The p35 relative, p49, inhibits mammalian and Drosophila caspases including DRONC and protects against apoptosis
    • Jabbour AM, Ekert PC, Coulson EJ, Knight MJ, Ashley DM, Hawkins CJ: The p35 relative, p49, inhibits mammalian and Drosophila caspases including DRONC and protects against apoptosis. Cell Death Differ. 9, 1311-1320 (2002).
    • (2002) Cell Death Differ , vol.9 , pp. 1311-1320
    • Jabbour, A.M.1    Ekert, P.C.2    Coulson, E.J.3    Knight, M.J.4    Ashley, D.M.5    Hawkins, C.J.6
  • 31
    • 0037073721 scopus 로고    scopus 로고
    • Characterization of the apoptosis suppressor protein p49 from the Spodoptera littoralis nucleopolyhedrovirus
    • Pei Z, Reske G, Huang Q, Hammock BD, Qi Y, Chejanovsky N: Characterization of the apoptosis suppressor protein p49 from the Spodoptera littoralis nucleopolyhedrovirus. J. Biol. Chem. 277, 48677-48684 (2002).
    • (2002) J. Biol. Chem , vol.277 , pp. 48677-48684
    • Pei, Z.1    Reske, G.2    Huang, Q.3    Hammock, B.D.4    Qi, Y.5    Chejanovsky, N.6
  • 32
    • 34548171631 scopus 로고    scopus 로고
    • Baculovirus caspace inhibitors p49 and p35 block virus-induced apoptosis downstream of effector caspase DrICE activation in Drosophila melanogaster cells
    • Lannan E, Vandergaast R, Friesen PD: Baculovirus caspace inhibitors p49 and p35 block virus-induced apoptosis downstream of effector caspase DrICE activation in Drosophila melanogaster cells. J. Virol. 81, 9319-9330 (2007).
    • (2007) J. Virol , vol.81 , pp. 9319-9330
    • Lannan, E.1    Vandergaast, R.2    Friesen, P.D.3
  • 33
    • 13444301379 scopus 로고    scopus 로고
    • Functional analysis of the inhibitor of apoptosis (iap) gene carried by the entomopoxvirus of Amsacta moorei
    • Li Q, Liston P, Moyer RW: Functional analysis of the inhibitor of apoptosis (iap) gene carried by the entomopoxvirus of Amsacta moorei. J. Virol. 79, 2335-2345 (2005).
    • (2005) J. Virol , vol.79 , pp. 2335-2345
    • Li, Q.1    Liston, P.2    Moyer, R.W.3
  • 34
    • 33750984207 scopus 로고    scopus 로고
    • Mutation of the Myxoma virus SERP2 PI-site to prevent proteinase inhibition causes apoptosis in cultured RK-13 cells and attenuates disease in rabbits, but mutation to alter specificity causes apoptosis without reducing virulence
    • MacNeill AL, Turner PC, Moyer RW: Mutation of the Myxoma virus SERP2 PI-site to prevent proteinase inhibition causes apoptosis in cultured RK-13 cells and attenuates disease in rabbits, but mutation to alter specificity causes apoptosis without reducing virulence. Virology 356, 12-22 (2006).
    • (2006) Virology , vol.356 , pp. 12-22
    • MacNeill, A.L.1    Turner, P.C.2    Moyer, R.W.3
  • 36
    • 34447323097 scopus 로고    scopus 로고
    • Drosophila Omi, a mitochondrial-localized iap antagonist and proapoptotic serine protease
    • Challa M, Malladi S, Pellock BJ et al.: Drosophila Omi, a mitochondrial-localized iap antagonist and proapoptotic serine protease. EMBO J. 26, 3144-3156 (2007).
    • (2007) EMBO J , vol.26 , pp. 3144-3156
    • Challa, M.1    Malladi, S.2    Pellock, B.J.3
  • 37
    • 34247603036 scopus 로고    scopus 로고
    • Role of mitochondrial remodeling in programmed cell death in Drosophila melanogaster
    • Goyal G, Fell B, Sarin A, Youle RJ, Sriram V: Role of mitochondrial remodeling in programmed cell death in Drosophila melanogaster. Dev. Cell. 12, 807-816 (2007).
    • (2007) Dev. Cell , vol.12 , pp. 807-816
    • Goyal, G.1    Fell, B.2    Sarin, A.3    Youle, R.J.4    Sriram, V.5
  • 38
    • 0028106463 scopus 로고
    • Expression of the 39 k promoter of Autographa californica nuclear polyhedrosis virus is increased by the apoptotic suppressor p35
    • Gong M, Guarino LA: Expression of the 39 k promoter of Autographa californica nuclear polyhedrosis virus is increased by the apoptotic suppressor p35. Virology 204, 38-44 (1994).
    • (1994) Virology , vol.204 , pp. 38-44
    • Gong, M.1    Guarino, L.A.2
  • 40
    • 1342321888 scopus 로고    scopus 로고
    • The role of baculovirus apoptotic suppressors in AcMNPV-mediated translation arrest in Ld652Y cells
    • Thiem SM, Chejanovsky N: The role of baculovirus apoptotic suppressors in AcMNPV-mediated translation arrest in Ld652Y cells. Virology 319, 292-306 (2004).
    • (2004) Virology , vol.319 , pp. 292-306
    • Thiem, S.M.1    Chejanovsky, N.2
  • 41
    • 0242320350 scopus 로고    scopus 로고
    • Baculovirus p35 interacts with a subunit of human RNA polymerase II and can enhance promoter activity in human cells
    • Takramah D, Sieiffert BM, Schaller S, Vigneron M, Hacker G: Baculovirus p35 interacts with a subunit of human RNA polymerase II and can enhance promoter activity in human cells. J. Gen. Virol. 84, 3011-3019 (2003).
    • (2003) J. Gen. Virol , vol.84 , pp. 3011-3019
    • Takramah, D.1    Sieiffert, B.M.2    Schaller, S.3    Vigneron, M.4    Hacker, G.5
  • 42
    • 0032562676 scopus 로고    scopus 로고
    • The baculovirus anti-apoptotic p35 protein promotes transfomation of mouse embryo fibroblasts
    • Resnicoff M, Valentinis B, Herbert D et al.: The baculovirus anti-apoptotic p35 protein promotes transfomation of mouse embryo fibroblasts. J. Biol. Chem. 273, 10376-10380 (1998).
    • (1998) J. Biol. Chem , vol.273 , pp. 10376-10380
    • Resnicoff, M.1    Valentinis, B.2    Herbert, D.3
  • 43
    • 38549141229 scopus 로고    scopus 로고
    • Exploring the extremes of sequence/structure space with ensemble fold recognition in the program Phyre
    • Bennett-Lovsey RM, Herbert AD, Sternberg MJ, Kelly LA: Exploring the extremes of sequence/structure space with ensemble fold recognition in the program Phyre. Proteins 70, 611-625 (2008).
    • (2008) Proteins , vol.70 , pp. 611-625
    • Bennett-Lovsey, R.M.1    Herbert, A.D.2    Sternberg, M.J.3    Kelly, L.A.4
  • 44
    • 3242810318 scopus 로고    scopus 로고
    • MEGA3: Integrated software for molecular evolutionary genetics analysis and sequence alignment
    • Kumar S, Tamura K, Nei M: MEGA3: integrated software for molecular evolutionary genetics analysis and sequence alignment. Brief Bioinformatics 5, 150-163 (2004).
    • (2004) Brief Bioinformatics , vol.5 , pp. 150-163
    • Kumar, S.1    Tamura, K.2    Nei, M.3


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