메뉴 건너뛰기




Volumn 118, Issue 11, 2008, Pages 3598-3608

Calsarcin-2 deficiency increases exercise capacity in mice through calcineurin/NFAT activation

Author keywords

[No Author keywords available]

Indexed keywords

CALCINEURIN; CALSARCIN 2; MUSCLE PROTEIN; TRANSCRIPTION FACTOR NFAT; UNCLASSIFIED DRUG;

EID: 55849135238     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI36277     Document Type: Article
Times cited : (127)

References (42)
  • 1
    • 33746328957 scopus 로고    scopus 로고
    • Signaling pathways in skeletal muscle remodeling
    • Bassel-Duby, R., and Olson, E.N. 2006. Signaling pathways in skeletal muscle remodeling. Annu. Rev. Biochem. 75:19-37.
    • (2006) Annu. Rev. Biochem , vol.75 , pp. 19-37
    • Bassel-Duby, R.1    Olson, E.N.2
  • 2
    • 0030888186 scopus 로고    scopus 로고
    • Differential activation of transcription factors induced by Ca2+ response amplitude and duration
    • Dolmetsch, R.E., Lewis, R.S., Goodnow, C.C., and Healy, J.I. 1997. Differential activation of transcription factors induced by Ca2+ response amplitude and duration. Nature. 386:855-858.
    • (1997) Nature , vol.386 , pp. 855-858
    • Dolmetsch, R.E.1    Lewis, R.S.2    Goodnow, C.C.3    Healy, J.I.4
  • 3
    • 0242606147 scopus 로고    scopus 로고
    • Role of calcineurin in striated muscle: Development, adaptation, and disease
    • Bassel-Duby, R., and Olson, E.N. 2003. Role of calcineurin in striated muscle: development, adaptation, and disease. Biochem. Biophys. Res. Commun. 311:1133-1141.
    • (2003) Biochem. Biophys. Res. Commun , vol.311 , pp. 1133-1141
    • Bassel-Duby, R.1    Olson, E.N.2
  • 4
    • 34548264161 scopus 로고    scopus 로고
    • Activity-dependent signaling pathways controlling muscle diversity and plasticity
    • Schiaffino, S., Sandri, M., and Murgia, M. 2007. Activity-dependent signaling pathways controlling muscle diversity and plasticity. Physiology (Bethesda). 22:269-278.
    • (2007) Physiology (Bethesda) , vol.22 , pp. 269-278
    • Schiaffino, S.1    Sandri, M.2    Murgia, M.3
  • 5
    • 0032529188 scopus 로고    scopus 로고
    • A calcineurin-dependent transcriptional pathway controls skeletal muscle fiber type
    • Chin, E.R., et al. 1998. A calcineurin-dependent transcriptional pathway controls skeletal muscle fiber type. Genes Dev. 12:2499-2509.
    • (1998) Genes Dev , vol.12 , pp. 2499-2509
    • Chin, E.R.1
  • 6
    • 0033838874 scopus 로고    scopus 로고
    • A calcineurin-NFATc3-dependent pathway regulates skeletal muscle differentiation and slow myosin heavy-chain expression
    • Delling, U., et al. 2000. A calcineurin-NFATc3-dependent pathway regulates skeletal muscle differentiation and slow myosin heavy-chain expression. Mol. Cell. Biol. 20:6600-6611.
    • (2000) Mol. Cell. Biol , vol.20 , pp. 6600-6611
    • Delling, U.1
  • 7
    • 0034681315 scopus 로고    scopus 로고
    • Stimulation of slow skeletal muscle fiber gene expression by calcineurin in vivo
    • Naya, F.J., et al. 2000. Stimulation of slow skeletal muscle fiber gene expression by calcineurin in vivo. J. Biol. Chem. 275:4545-4548.
    • (2000) J. Biol. Chem , vol.275 , pp. 4545-4548
    • Naya, F.J.1
  • 8
    • 2942746423 scopus 로고    scopus 로고
    • Genetic loss of calcineurin blocks mechanical overload-induced skeletal muscle fiber type switching but not hypertrophy
    • Parsons, S.A., et al. 2004. Genetic loss of calcineurin blocks mechanical overload-induced skeletal muscle fiber type switching but not hypertrophy. J. Biol. Chem. 279:26192-26200.
    • (2004) J. Biol. Chem , vol.279 , pp. 26192-26200
    • Parsons, S.A.1
  • 9
    • 0034687814 scopus 로고    scopus 로고
    • Calsarcins, a novel family of sarcomeric calcineurin-binding proteins
    • Frey, N., Richardson, J.A., and Olson, E.N. 2000. Calsarcins, a novel family of sarcomeric calcineurin-binding proteins. Proc. Natl. Acad. Sci. U. S. A. 97:14632-14637.
    • (2000) Proc. Natl. Acad. Sci. U. S. A , vol.97 , pp. 14632-14637
    • Frey, N.1    Richardson, J.A.2    Olson, E.N.3
  • 10
    • 33744494538 scopus 로고    scopus 로고
    • The sarcomeric Z-disc: A nodal point in signalling and disease
    • Frank, D., Kuhn, C., Katus, H.A., and Frey, N. 2006. The sarcomeric Z-disc: a nodal point in signalling and disease. J. Mol. Med. 84:446-468.
    • (2006) J. Mol. Med , vol.84 , pp. 446-468
    • Frank, D.1    Kuhn, C.2    Katus, H.A.3    Frey, N.4
  • 11
    • 0035852783 scopus 로고    scopus 로고
    • Myozenin: An alpha-actinin-and gamma-filamin-binding protein of skeletal muscle Z lines
    • Takada, F., et al. 2001. Myozenin: an alpha-actinin-and gamma-filamin-binding protein of skeletal muscle Z lines. Proc. Natl. Acad. Sci. U. S. A. 98:1595-1600.
    • (2001) Proc. Natl. Acad. Sci. U. S. A , vol.98 , pp. 1595-1600
    • Takada, F.1
  • 12
    • 0034731460 scopus 로고    scopus 로고
    • FATZ, a filamin-, actinin-, and telethonin-binding protein of the Z-disc of skeletal muscle
    • Faulkner, G., et al. 2000. FATZ, a filamin-, actinin-, and telethonin-binding protein of the Z-disc of skeletal muscle. J. Biol. Chem. 275:41234-41242.
    • (2000) J. Biol. Chem , vol.275 , pp. 41234-41242
    • Faulkner, G.1
  • 13
    • 0037134462 scopus 로고    scopus 로고
    • Calsarcin-3, a novel skeletal muscle-specific member of the calsarcin family, interacts with multiple Z-disc proteins
    • Frey, N., and Olson, E.N. 2002. Calsarcin-3, a novel skeletal muscle-specific member of the calsarcin family, interacts with multiple Z-disc proteins. J. Biol. Chem. 277:13998-14004.
    • (2002) J. Biol. Chem , vol.277 , pp. 13998-14004
    • Frey, N.1    Olson, E.N.2
  • 14
    • 24944550989 scopus 로고    scopus 로고
    • The Z-disc proteins myotilin and FATZ-1 interact with each other and are connected to the sarcolemma via muscle-specific filamins
    • Gontier, Y., et al. 2005. The Z-disc proteins myotilin and FATZ-1 interact with each other and are connected to the sarcolemma via muscle-specific filamins. J. Cell. Sci. 118:3739-3749.
    • (2005) J. Cell. Sci , vol.118 , pp. 3739-3749
    • Gontier, Y.1
  • 15
    • 19944423058 scopus 로고    scopus 로고
    • Mice lacking calsarcin-1 are sensitized to calcineurin signaling and show accelerated cardiomyopathy in response to pathological biomechanical stress
    • Frey, N., et al. 2004. Mice lacking calsarcin-1 are sensitized to calcineurin signaling and show accelerated cardiomyopathy in response to pathological biomechanical stress. Nat. Med. 10:1336-1343.
    • (2004) Nat. Med , vol.10 , pp. 1336-1343
    • Frey, N.1
  • 16
    • 36549048367 scopus 로고    scopus 로고
    • Calsarcin-1 protects against angiotensin-II induced cardiac hypertrophy
    • Frank, D., et al. 2007. Calsarcin-1 protects against angiotensin-II induced cardiac hypertrophy. Circulation. 116:2587-2596.
    • (2007) Circulation , vol.116 , pp. 2587-2596
    • Frank, D.1
  • 17
    • 0041424822 scopus 로고    scopus 로고
    • Molecular mechanisms modulating muscle mass
    • Glass, D.J. 2003. Molecular mechanisms modulating muscle mass. Trends Mol. Med. 9:344-350.
    • (2003) Trends Mol. Med , vol.9 , pp. 344-350
    • Glass, D.J.1
  • 18
    • 33845674997 scopus 로고    scopus 로고
    • The transcriptional coactivator PGC-1beta drives the formation of oxidative type IIX fibers in skeletal muscle
    • Arany, Z., et al. 2007. The transcriptional coactivator PGC-1beta drives the formation of oxidative type IIX fibers in skeletal muscle. Cell Metab. 5:35-46.
    • (2007) Cell Metab , vol.5 , pp. 35-46
    • Arany, Z.1
  • 19
    • 0025782887 scopus 로고
    • Molecular and cellular adaptation of muscle in response to exercise: Perspectives of various models
    • Booth, F.W., and Thomason, D.B. 1991. Molecular and cellular adaptation of muscle in response to exercise: perspectives of various models. Physiol. Rev. 71:541-585.
    • (1991) Physiol. Rev , vol.71 , pp. 541-585
    • Booth, F.W.1    Thomason, D.B.2
  • 20
    • 0029896830 scopus 로고    scopus 로고
    • Molecular diversity of myofibrillar proteins: Gene regulation and functional significance
    • Schiaffino, S., and Reggiani, C. 1996. Molecular diversity of myofibrillar proteins: gene regulation and functional significance. Physiol. Rev. 76:371-423.
    • (1996) Physiol. Rev , vol.76 , pp. 371-423
    • Schiaffino, S.1    Reggiani, C.2
  • 21
    • 0032540267 scopus 로고    scopus 로고
    • A calcineurin-dependent transcriptional pathway for cardiac hypertrophy
    • Molkentin, J.D., et al. 1998. A calcineurin-dependent transcriptional pathway for cardiac hypertrophy. Cell. 93:215-228.
    • (1998) Cell , vol.93 , pp. 215-228
    • Molkentin, J.D.1
  • 22
    • 35248837988 scopus 로고    scopus 로고
    • Renaming the DSCR1/Adapt78 gene family as RCAN: Regulators of calcineurin
    • Davies, K.J., et al. 2007. Renaming the DSCR1/Adapt78 gene family as RCAN: regulators of calcineurin. FASEB J. 21:3023-3028.
    • (2007) FASEB J , vol.21 , pp. 3023-3028
    • Davies, K.J.1
  • 23
    • 0034624137 scopus 로고    scopus 로고
    • Independent signals control expression of the calcineurin inhibitory proteins MCIP1 and MCIP2 in striated muscles
    • Yang, J., et al. 2000. Independent signals control expression of the calcineurin inhibitory proteins MCIP1 and MCIP2 in striated muscles. Circ. Res. 87:E61-E68.
    • (2000) Circ. Res , vol.87
    • Yang, J.1
  • 24
    • 0036234543 scopus 로고    scopus 로고
    • NFAT signaling: Choreographing the social lives of cells
    • Crabtree, G.R., and Olson, E.N. 2002. NFAT signaling: choreographing the social lives of cells. Cell. 109(Suppl.):S67-S79.
    • (2002) Cell , vol.109 , Issue.SUPPL.
    • Crabtree, G.R.1    Olson, E.N.2
  • 26
    • 0031694618 scopus 로고    scopus 로고
    • Activation and cellular localization of the cyclosporine A-sensitive transcription factor NF-AT in skeletal muscle cells
    • Abbott, K.L., Friday, B.B., Thaloor, D., Murphy, T.J., and Pavlath, G.K. 1998. Activation and cellular localization of the cyclosporine A-sensitive transcription factor NF-AT in skeletal muscle cells. Mol. Biol. Cell. 9:2905-2916.
    • (1998) Mol. Biol. Cell , vol.9 , pp. 2905-2916
    • Abbott, K.L.1    Friday, B.B.2    Thaloor, D.3    Murphy, T.J.4    Pavlath, G.K.5
  • 27
    • 0038236734 scopus 로고    scopus 로고
    • Calcineurin is a potent regulator for skeletal muscle regeneration by association with NFATc1 and GATA-2
    • Sakuma, K., et al. 2003. Calcineurin is a potent regulator for skeletal muscle regeneration by association with NFATc1 and GATA-2. Acta Neuropathol. 105:271-280.
    • (2003) Acta Neuropathol , vol.105 , pp. 271-280
    • Sakuma, K.1
  • 28
    • 0037102256 scopus 로고    scopus 로고
    • Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibres
    • Lin, J., et al. 2002. Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibres. Nature. 418:797-801.
    • (2002) Nature , vol.418 , pp. 797-801
    • Lin, J.1
  • 29
    • 8844276054 scopus 로고    scopus 로고
    • Regulation of muscle fiber type and running endurance by PPARdelta
    • Wang, Y.X., et al. 2004. Regulation of muscle fiber type and running endurance by PPARdelta. PLoS Biol. 2:e294.
    • (2004) PLoS Biol , vol.2
    • Wang, Y.X.1
  • 30
    • 22144434964 scopus 로고    scopus 로고
    • Transcriptional coactivator PGC-1 alpha controls the energy state and contractile function of cardiac muscle
    • Arany, Z., et al. 2005. Transcriptional coactivator PGC-1 alpha controls the energy state and contractile function of cardiac muscle. Cell Metab. 1:259-271.
    • (2005) Cell Metab , vol.1 , pp. 259-271
    • Arany, Z.1
  • 31
    • 0037979119 scopus 로고    scopus 로고
    • Altered skeletal muscle phenotypes in calcineurin Aalpha and Abeta gene-targeted mice
    • Parsons, S.A., Wilkins, B.J., Bueno, O.F., and Molkentin, J.D. 2003. Altered skeletal muscle phenotypes in calcineurin Aalpha and Abeta gene-targeted mice. Mol. Cell. Biol. 23:4331-4343.
    • (2003) Mol. Cell. Biol , vol.23 , pp. 4331-4343
    • Parsons, S.A.1    Wilkins, B.J.2    Bueno, O.F.3    Molkentin, J.D.4
  • 32
    • 15244351709 scopus 로고    scopus 로고
    • Transcriptional reprogramming and ultrastructure during atrophy and recovery of mouse soleus muscle
    • Dapp, C., Schmutz, S., Hoppeler, H., and Fluck, M. 2004. Transcriptional reprogramming and ultrastructure during atrophy and recovery of mouse soleus muscle. Physiol. Genomics. 20:97-107.
    • (2004) Physiol. Genomics , vol.20 , pp. 97-107
    • Dapp, C.1    Schmutz, S.2    Hoppeler, H.3    Fluck, M.4
  • 33
    • 10144228501 scopus 로고    scopus 로고
    • Calcineurin activation influences muscle phenotype in a muscle-specific fashion
    • Talmadge, R.J., et al. 2004. Calcineurin activation influences muscle phenotype in a muscle-specific fashion. BMC Cell Biol. 5:28.
    • (2004) BMC Cell Biol , vol.5 , pp. 28
    • Talmadge, R.J.1
  • 34
    • 34748849262 scopus 로고    scopus 로고
    • Loss of ACTN3 gene function alters mouse muscle metabolism and shows evidence of positive selection in humans
    • MacArthur, D.G., et al. 2007. Loss of ACTN3 gene function alters mouse muscle metabolism and shows evidence of positive selection in humans. Nat. Genet. 39:1261-1265.
    • (2007) Nat. Genet , vol.39 , pp. 1261-1265
    • MacArthur, D.G.1
  • 35
    • 0037066459 scopus 로고    scopus 로고
    • Regulation of mitochondrial biogenesis in skeletal muscle by CaMK
    • Wu, H., et al. 2002. Regulation of mitochondrial biogenesis in skeletal muscle by CaMK. Science. 296:349-352.
    • (2002) Science , vol.296 , pp. 349-352
    • Wu, H.1
  • 36
    • 17944382249 scopus 로고    scopus 로고
    • Activation of MEF2 by muscle activity is mediated through a calcineurin-dependent pathway
    • Wu, H., et al. 2001. Activation of MEF2 by muscle activity is mediated through a calcineurin-dependent pathway. EMBO J. 20:6414-6423.
    • (2001) EMBO J , vol.20 , pp. 6414-6423
    • Wu, H.1
  • 37
    • 34848858523 scopus 로고    scopus 로고
    • Histone deacetylase degradation and MEF2 activation promote the formation of slow-twitch myofibers
    • Potthoff, M.J., et al. 2007. Histone deacetylase degradation and MEF2 activation promote the formation of slow-twitch myofibers. J. Clin. Invest. 117:2459-2467.
    • (2007) J. Clin. Invest , vol.117 , pp. 2459-2467
    • Potthoff, M.J.1
  • 38
    • 44349182652 scopus 로고    scopus 로고
    • Protein kinase D1 stimulates MEF2 activity in skeletal muscle and enhances performance
    • Kim, M., et al. 2008. Protein kinase D1 stimulates MEF2 activity in skeletal muscle and enhances performance. Mol. Cell. Biol. 28:3600-3609.
    • (2008) Mol. Cell. Biol , vol.28 , pp. 3600-3609
    • Kim, M.1
  • 39
    • 0032948848 scopus 로고    scopus 로고
    • A common nonsense mutation results in alpha-actinin-3 deficiency in the general population
    • North, K.N., et al. 1999. A common nonsense mutation results in alpha-actinin-3 deficiency in the general population. Nat. Genet. 21:353-354.
    • (1999) Nat. Genet , vol.21 , pp. 353-354
    • North, K.N.1
  • 40
    • 0041385595 scopus 로고    scopus 로고
    • ACTN3 genotype is associated with human elite athletic performance
    • Yang, N., et al. 2003. ACTN3 genotype is associated with human elite athletic performance. Am. J. Hum. Genet. 73:627-631.
    • (2003) Am. J. Hum. Genet , vol.73 , pp. 627-631
    • Yang, N.1
  • 41
    • 0030220198 scopus 로고    scopus 로고
    • Deficiency of a skeletal muscle isoform of alpha-actinin (alpha-actinin-3) in merosin-positive congenital muscular dystrophy
    • North, K.N., and Beggs, A.H. 1996. Deficiency of a skeletal muscle isoform of alpha-actinin (alpha-actinin-3) in merosin-positive congenital muscular dystrophy. Neuromuscul. Disord. 6:229-235.
    • (1996) Neuromuscul. Disord , vol.6 , pp. 229-235
    • North, K.N.1    Beggs, A.H.2
  • 42
    • 1542297759 scopus 로고    scopus 로고
    • A small molecular activator of cardiac hypertrophy uncovered in a chemical screen for modifiers of the calcineurin signaling pathway
    • Bush, E., et al. 2004. A small molecular activator of cardiac hypertrophy uncovered in a chemical screen for modifiers of the calcineurin signaling pathway. Proc. Natl. Acad. Sci. U. S. A. 101:2870-2875.
    • (2004) Proc. Natl. Acad. Sci. U. S. A , vol.101 , pp. 2870-2875
    • Bush, E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.