Somatic mutation rate of the APC gene

Japanese Journal of Clinical Oncology

Volumn 31, Issue 5, 2001, Pages 185-187

  Iwama, Takeo ^a  

^a SASAKI INSTITUTE   (Japan)

Author keywords

Adenoma of the colon; APC gene; Familial adenomatous polyposis; Somatic mutation rate

Indexed keywords

APC PROTEIN;

AGE; ARTICLE; CARCINOGENESIS; COLON ADENOMA; FAMILIAL COLON POLYPOSIS; FAMILIAL INCIDENCE; GENE; GENE INACTIVATION; GENE MUTATION; HUMAN; HUMAN CELL; MUTATION RATE; PARENT; POPULATION; POPULATION GENETICS; SOMATIC MUTATION; STEM CELL;

EID: 0034939017     PISSN: 03682811     EISSN: None     Source Type: Journal    
DOI: 10.1093/jjco/hye042     Document Type: Article

References (16)

1. Familial adenomatous polyposis (FAP): Frequency, penetrance and mutation rate
2. Detailed analysis of genetic alterations in colorectal tumors from patients with and without familial adenomatous polyposis (FAP)
3. Characteristic of somatic mutation of the adenomatous polyposis coli gene in colorectal tumors
4. Evidence against dominant negative mechanisms of intestinal polyp formation by APC gene mutations
5. Polyps and cancer of the large bowel: A necropsy study in Liverpool
6. Detection and treatment of diminutive colon adenomas
7. Colorectal cancer incidence linking model in familial adenomatous polyposis and the general population
8. Functional anatomy of the gastrointestinal tract
9. Normal appearances in colonic biopsy specimens
10. A pathological study of adenomatosis coli
11. Correlation between the location of germ-line mutation in the APC gene and the number of colorectal polyps in familial adenomatous polyposis patients
12. Population risk and physiological rate parameters for colon cancer. The union of an explicit model for carcinogenesis with the public health records of the United States
13. Phenotypic variability of familial adenomatous polyposis in 11 unrelated families with identical APC gene mutation
14. Randomized controlled trial of the effect of sulindac on duodenal and rectal polyposis and cell proliferation in patients with familial adenomatous polyposis
15. Analysis of adenomatous polyposis coli promoter hypermethylation in human cancer