Expression, activity, and function of phosphodiesterases in the mature and immature ductus arteriosus

Pediatric Research

Volumn 64, Issue 5, 2008, Pages 477-481

  Liu, Hanguan ^a   Manganiello, Vincent ^a   Waleh, Nahid ^b,c   Clyman, Ronald I ^d  

^a Laboratory of Cellular Metabolism

^b NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^c SRI INTERNATIONAL   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; MESSENGER RNA; NITRIC OXIDE; PHOSPHODIESTERASE; PHOSPHODIESTERASE I; PHOSPHODIESTERASE III; PHOSPHODIESTERASE INHIBITOR; PHOSPHODIESTERASE IV; PHOSPHODIESTERASE V; PROSTAGLANDIN; PROSTAGLANDIN E2; VASODILATOR AGENT;

ANIMAL TISSUE; ARTICLE; DUCTUS ARTERIOSUS; ENZYME ACTIVITY; FETUS; GENE EXPRESSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SMOOTH MUSCLE;

ANIMALS; AORTA; CYCLIC AMP; CYCLIC GMP; DINOPROSTONE; DOSE-RESPONSE RELATIONSHIP, DRUG; DUCTUS ARTERIOSUS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GESTATIONAL AGE; HYDROLYSIS; ISOENZYMES; PHOSPHODIESTERASE INHIBITORS; PHOSPHORIC DIESTER HYDROLASES; RNA, MESSENGER; SHEEP; UP-REGULATION; VASODILATION;

EID: 55849124376     PISSN: 00313998     EISSN: None     Source Type: Journal    
DOI: 10.1203/PDR.0b013e3181827c2c     Document Type: Article

References (32)

1. Clyman RI, Mauray F, Rudolph AM, Heymann MA 1980 Age-dependent sensitivity of the lamb ductus arteriosus to indomethacin and prostaglandins. J Pediatr 96:94-98
2. 2. J Pediatr 102: 907-911
3. Waleh N, Kajino H, Marrache AM, Ginzinger D, Roman C, Seidner SR, Moss TJ, Fouron JC, Vazquez-Tello A, Chemtob S, Clyman RI 2004 Prostaglandin E2-mediated relaxation of the ductus arteriosus: effects of gestational age on g protein-coupled receptor expression, signaling, and vasomotor control. Circulation 110:2326-2332
4. Bouayad A, Kajino H, Waleh N, Fouron JC, Andelfinger G, Varma DR, Skoll A, Vazquez A, Gobeil F Jr., Clyman RI, Chemtob S 2001 Characterization of PGE2 receptors in fetal and newborn lamb dutlus arteriosus. Am J Pbysiol Heart Circ Physiol 280:H2342-H2349
5. Manganiello VC, Degerman E 1999 Cyclic nucleotide phosphodiesterases (PDEs): diverse regulators of cyclic nucleotide signals and inviting molecular targets for novel therapeutic agents. Thromb Haemost 82:407-411
6. Soderling SH, Beavo JA 2000 Regulation of cAMP and cGMP signaling: new phosphodiesterases and new functions. Curr Opin Cell Biol 12:174-179
7. Maurice DH, Palmer D, Tilley DG, Dunkerley HA, Netherton SJ, Raymond DR, Elbatarny HS, Jimmo SL 2003 Cyclic nucleotide phosphodiesterase activity, expression, and targeting in cells of the cardiovascular system. Mol Pharmacol 64:533-546
8. Rybalkin SD, Yan C, Bornfeldt KE, Beavo JA 2003 Cyclic GMP phosphodiesterases and regulation of smooth muscle function. Circ Res 93:280-291
9. Poison JB, Strada SJ 1996 Cyclic nucleotide phosphodiesterases and vascular smooth muscle. Annu Rev Pharmacol Toxicol 36:403-427
10. Thebaud B, Michelakis E, Wu XC, Harry G, Hashimoto K, Archer SL 2002 Sildenafil reverses O2 constriction of the rabbit ductus arteriosus by inhibiting type 5 phosphodiesterase and activating BK(Ca) channels. Pediatr Res 52:19-24
11. Toyoshima K, Momma K, Imamura S, Nakanishi T 2006 In vivo dilatation of the fetal and postnatal ductus arteriosus by inhibition of phosphodiesterase 3 in rats. Biol Neonate 89:251-256
12. Momma K, Toyoshima K, Imamura S, Nakanishi T 2005 In vivo dilation of fetal and neonatal ductus arteriosus by inhibition of phosphodiesterase-5 in rats. Pediatr Res 58:42-45
13. Kajino H, Chen YQ, Seidner SR, Waleh N, Mauray F, Roman C, Chemtob S, Koch CJ, Clyman RI 2001 Factors that increase the contractile tone of the Ductus Arteriosus also regulate its anatomic remodeling. Am J Physiol Regul Integr Comp Physiol 281:R291-R301
14. Clyman RI, Mauray F, Wong L, Heymann MA, Rudolph AM 1978 The developmental response of the ductus arteriosus to oxygen. Biol Neonate 34:177-181
15. Karaki H, Ozaki H, Hori M, Mitsui-Saito M, Amano K, Harada K, Miyamoto S, Nakazawa H, Won KJ, Sato K 1997 Calcium movements, distribution, and functions in smooth muscle. Pharmacol Rev 49:157-230
16. Lee MR, Li L, Kitazawa T 1997 Cyclic GMP causes Ca2+ desensitization in vascular smooth muscle by activating the myosin light chain phosphatase. J Biol Chem 272:5063-5068
17. Savineau JP, Marthan R 1997 Modulation of the calcium sensitivity of the smooth muscle contractile apparatus: molecular mechanisms, pharmacological and pathophysiological implications. Fundam Clin Pharmacol 11:289-299
18. Rybalkin SD, Bornfeldt KE, Sonnenburg WK, Rybalkina IG, Kwak KS, Hanson K, Krebs EG, Beavo JA 1997 Calmodulin-stimulated cyclic nucleotide phosphodiesterase (PDE1C) is induced in human arterial smooth muscle cells of the synthetic, proliferative phenotype. J Clin Invest 100:2611-2621
19. Rybalkin SD, Rybalkina I, Beavo JA, Bornfeldt KE 2002 Cyclic nucleotide phosphodiesterase 1C promotes human arterial smooth muscle cell proliferation. Circ Res 90:151-157
20. Zhao AZ, Yan C, Sonnenburg WK, Beavo JA 1997 Recent advances in the study of Ca2+/CaM-activated phosphodiesterases: expression and physiological functions. Adv Second Messenger Phosphoprotein Res 31:237-251
21. Kakkar R, Raju RV, Sharma RK 1999 Calmodulin-dependent cyclic nucleotide phosphodiesterase (PDEl). Cell Mol Life Sci 55:1164-1186
22. Netherton SJ, Jimmo SL, Palmer D, Tilley DG, Dunkerley HA, Raymond DR, Russell JC, Absher PM, Sage EH, Vernon RB, Maurice DH 2002 Altered phosphodiesterase 3-mediated cAMP hydrolysis contributes to a hypermotile phenotype in obese JCR:LA-cp rat aortic vascular smooth muscle cells: implications for diabetesassociated cardiovascular disease. Diabetes 51:1194-1200
23. Pan X, Arauz E, Krzanowski JJ, Fitzpatrick DF, Poison JB 1994 Synergistic interactions between selective pharmacological inhibitors of phosphodiesterase isozyme families PDE III and PDE IV to attenuate proliferation of rat vascular smooth muscle cells. Biochem Pharmacol 48:827-835
24. Souness JE, Hassall GA, Parrott DP 1992 Inhibition of pig aortic smooth muscle cell DNA synthesis by selective type III and type IV cyclic AMP phosphodiesterase inhibitors. Biochem Pharmacol 44:857-866
25. Lindgren S, Andersson KE, Belfrage P, Degerman E, Manganiello VC 1989 Relaxant effects of the selective phosphodiesterase inhibitors milrinone and OPC 3911 on isolated human mesenteric vessels. Pharmacol Toxicol 64:440-445
26. Clyman RI, Chan CY, Mauray F, Chen YQ, Cox W, Seidner SR, Lord EM, Weiss H, Wale N, Evan SM, Koch CJ 1999 Permanent anatomic closure of the ductus arteriosus in newborn baboons: the roles of postnatal constriction, hypoxia, and gestation. Pediatr Res 45:19-29
27. Clyman RI, Waleh N, Black SM, Riemer RK, Mauray F, Chen YQ 1998 Regulation of ductus arteriosus patency by nitric oxide in fetal lambs. The role of gestation, oxygen tension and vasa vasorum. Pediatr Res 43:633-644
28. Baragatti B, Brizzi F, Ackerley C, Barogi S, Ballou LR, Coceani F 2003 Cyclooxygenase-1 and cyclooxygenase-2 in the mouse ductus arteriosus: individual activity and functional coupling with nitric oxide synthase. Br J Pharmacol 139:1505-1515
29. Baragatti B, Brizzi F, Barogi S, Laubach VE, Sodini D, Shesely EG, Regan RF, Coceani F 2007 Interactions between NO, CO and an endothelium-derived hyperpolarizing factor (EDHF) in maintaining patency of the ductus arteriosus in the mouse. Br J Pharmacol 151:54-62
30. Toyoshima K, Momma K, Imamura S, Nakanishi T 2007 In vivo dilatation of the postnatal ductus arteriosus by atrial natriuretic peptide in the rat. Neonatology 92:139-144
31. Kloner RA 2000 Cardiovascular risk and sildenafil. Am J Cardiol 86:57F-61F
32. Rybalkin SD, Rybalkina IG, Shimizu-Albergine M, Tang XB, Beavo JA 2003 PDE5 is converted to an activated state upon cGMP binding to the GAF A domain. EMBO J 22:469-478