Eye-head coordination in moderately affected Huntington's disease patients: Do head movements facilitate gaze shifts?

Experimental Brain Research

Volumn 192, Issue 1, 2009, Pages 97-112

  Becker, W ^a   Jurgens R ^a   Kassubek, J ^a   Ecker, D ^a   Kramer, B ^a   Landwehrmeyer, B ^a  

^a UNIVERSITY OF ULM   (Germany)

Author keywords

Antisaccades; Delayed saccades; Eye head coordination; Gaze saccades; Head velocity; Huntington's disease

Indexed keywords

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; EYE MOVEMENT CONTROL; EYE POSITION; EYE TRACKING; FEMALE; GAZE; HEAD MOVEMENT; HEAD POSITION; HUMAN; HUNTINGTON CHOREA; LATENT PERIOD; MALE; ONSET AGE; PRIORITY JOURNAL; SACCADIC EYE MOVEMENT; VISUOMOTOR COORDINATION;

ADAPTATION, PHYSIOLOGICAL; ADULT; AGE FACTORS; BRAIN; EYE MOVEMENTS; FEMALE; FIXATION, OCULAR; HEAD MOVEMENTS; HUMANS; HUNTINGTON DISEASE; MALE; MIDDLE AGED; NECK MUSCLES; NEUROPSYCHOLOGICAL TESTS; OCULAR MOTILITY DISORDERS; OCULOMOTOR MUSCLES; PHOTIC STIMULATION; PSYCHOMOTOR PERFORMANCE; REACTION TIME; SACCADES; TIME FACTORS;

EID: 55849103175     PISSN: 00144819     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00221-008-1559-6     Document Type: Article

References (71)

1. GE Alexander MD Crutcher MR DeLong 1990 Basal ganglia-thalamocortical circuits: parallel substrates for motor, oculomotor, "prefrontal" and "limbic" functions Prog Brain Res 85 119 146
2. FR Ali AW Michell RA Barker RH Carpenter 2006 The use of quantitative oculometry in the assessment of Huntington's disease Exp Brain Res 169 237 245
3. C André-Deshays A Berthoz M Revel 1988 Eye-head coupling in humans. I. Simultaneous recording of isolated motor units in dorsal neck muscles and horizontal eye movements Exp Brain Res 69 399 406
4. C André-Deshays M Revel A Berthoz 1991 Eye-head coupling in humans. II. Phasic components Exp Brain Res 84 359 366
5. SE Andrew YP Goldberg B Kremer H Telenius J Theilmann S Adam E Starr F Squitieri B Lin MA Kalchman 1993 The relationship between trinucleotide (CAG) repeat length and clinical features of Huntington's disease Nat Genet 4 398 403
6. G Avanzini F Girotti T Caraceni R Spreafico 1979 Oculomotor disorders in Huntington's disease J Neurol Neurosurg Psychiatr 42 581 589
7. GR Barnes 1979 Vestibulo-ocular function during co-ordinated head and eye movements to acquire visual targets J Physiol (Lond) 287 127 147
8. Becker W, Jürgens R (1992) Gaze saccades to visual targets: does head movement change the metrics? In: Berthoz A, Vidal PP, Graf W (eds) The Head-neck sensory motor system. Oxford University Press, New York, Oxford, pp 427-433
9. N Beenen U Büttner HW Lange 1986 The diagnostic value of eye movement recording in patients with Huntington's disease and their offspring Electroencephalogr Clin Neurophysiol 63 119 127
10. TM Blekher RD Yee SC Kirkwood AM Hake JC Stout MR Weaver TM Foroud 2004 Oculomotor control in asymptomatic and recently diagnosed individuals with the genetic marker for Huntington's disease Vision Res 44 2729 2736
11. T Blekher SA Johnson J Marshall K White S Hui M Weaver J Gray R Yee JC Stout X Beristain J Wojcieszek T Foroud 2006 Saccades in presymptomatic and early stages of Huntington's disease Neurology 67 394 399
12. E Bollen JPH Reulen JPH Den Heyer W Van der Kamp RAC Roos OJS Buruma 1986 Horizontal and vertical saccadic eye movement abnormalities in Huntinton's Chorea J Neurosci 74 11 22
13. RR Brinkman MM Mezei J Theilmann E Almqvist MR Hayden 1997 The likelihood of being affected with Huntington disease by a particular age, for a specific CAG size Am J Hum Genet 60 1202 1210
14. JA Büttner-Ennever U Büttner B Cohen G Baumgartner 1982 Vertical gaze paralysis and the rostral interstitial nucleus of the medial longitudinal fasciculus Brain 105 125 149
15. F Chan IT Armstrong G Pari RJ Riopelle DP Munoz 2005 Deficits in saccadic eye-movement control in Parkinson's disease Neuropsychologia 43 784 796
16. H Collewijn LN Went EP Tamminga M Vegter-Van der Vlis 1988 Oculomotor defects in patients with Huntington's disease and their offspring J Neurosci 86 307 320
17. RJ Cowie DL Robinson 1994 Subcortical contributions to head movements in macaques. I. Contrasting effects of electrical stimulation of a medial pontomedullary region and the superior colliculus J Neurophysiol 72 2648 2664
18. RJ Cowie MK Smith DL Robinson 1994 Subcortical contributions to head movements in macaques. II. Connections of a medial pontomedullary head-movement region J Neurophysiol 72 2665 2682
19. J Currie B Ramsden C McArthur P Maruff 1991 Validation of a clinical antsaccadic eye movement test in the assessment of dementia Arch Neurol 48 644 648
20. CE Curtis ME Calkins WM Grove KJ Feil WG Lacono 2001 Saccadic disinhibition in patients with acute and remitted schizophrenia and their first-degree biological relatives Am J Psychiatr 158 100 106
21. M Duyao C Ambrose R Myers A Novelletto F Persichetti M Frontali S Folstein C Ross M Franz M Abbott 1993 Trinucleotide repeat length instability and age of onset in Huntington's disease Nat Genet 4 387 392
22. EG Freedman S Quessy 2004 Electrical stimulation of rhesus monkey nucleus reticularis gigantocellularis-II. Effects on metrics and kinematics of ongoing gaze shifts to visual targets Exp Brain Res 156 357 376
23. EG Freedman DL Sparks 1997 Eye-head coordination during head-unrestrained gaze shifts in rhesus monkey J Neurophysiol 772 2328 2348
24. J Fukushima K Fukushima K Miyasaka I Yamashita 1994 Voluntary control of saccadic eye movement in patients with frontal cortical lesions and Parkinsonian patients in comparison with that in schizophrenics Biol Psychiatry 36 21 30
25. JH Fuller 1996 Eye position and target amplitude effects on human visual saccadic latencies Exp Brain Res 109 457 466
26. P Garcia-Ruiz A Fontán C Cenjor E Ulmer E Gomez Tortosa R Sanchez Pernaute A Rojo J García de Yébenez 2001 Störung der Blicksakkaden bei der Huntington-Krankheit. Klinische Korrelationen Nervenarzt 72 437 440
27. CVP Golding C Danchaivijtr TL Hodgson SJ Tabrizi C Kennard 2006 Identification of an oculomotor biomarker of preclinical Huntington disease Neurology 67 485 487
28. JE Goldring MC Dorris BD Corneil PA Ballantyne DP Munoz 1996 Combined eye-head gaze shifts to visual and auditory targets in humans Exp Brain Res 111 68 78
29. Henn V, Büttner U (1982) Disorders of horizontal gaze. In: Lennerstrand G, Zee DS, Keller EL (eds) Functional basis of ocular motility disorders. Pergamon Press, Oxford, pp 239-245
30. V Henn W Lang K Hepp H Reisine 1984 Experimental gaze palsies in monkeys and their relation to human pathology Brain 107 619 636
31. O Hikosaka RH Wurtz 1985 Modification of saccadic eye movements by GABA-related substances. I. Effect of muscimol and bicuculline in monkey superior colliculus J Neurophysiol 53 266 291
32. O Hikosaka RH Wurtz 1985 Modification of saccadic eye movements by GABA-related substances. II. Effects of muscimol in monkey substantia nigra pars reticulata J Neurophysiol 53 292 309
33. O Hikosaka Y Takikawa R Kawagoe 2000 Role of the basal ganglia in the control of purposive saccadic eye movements Physiol Rev 80 953 978
34. Huntington's Disease Collaborative Research group 1993 A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes Cell 72 971 983
35. CRS Kaneko 1996 Effect of ibotenic acid lesions of the omnipause neurons on saccadic eye movements in rhesus monkey J Neurophysiol 75 2229 2242
36. TA Knight AF Fuchs 2007 Contribution of the frontal eye field to gaze shifts in the head-unrestrained monkey: Effects of microstimulation J Neurophysiol 98 618 634
37. AH Koeppen 1989 The nucleus pontis centralis caudalis in Huntington's disease J Neurol Sci 91 129 141
38. AG Lasker DS Zee 1997 Ocular motor abnormalities in Huntington's disease Vision Res 37 3639 3645
39. AG Lasker DS Zee TC Hain SE Folstein HS Singer 1987 Saccades in Huntington's disease: initiation defects and distractibility Neurology 37 364 370
40. AG Lasker DS Zee TC Hain SE Folstein HS Singer 1988 Saccades in Huntington's disease: slowing and dysmetria Neurology 38 427 431
41. VP Laurutis DA Robinson 1986 The vestibulo-ocular reflex during human saccadic eye movements J Physiol (Lond) 373 209 233
42. RJ Leigh SA Newman SE Folstein AG Lasker BA Jensen 1983 Abnormal ocular motor control in Huntington's disease Neurology 33 1268 1275
43. RJ Leigh IM Parhad AW Clark JA Buettner-Ennever SE Folstein 1985 Brainstem findings in Huntington's disease. Possible mechanisms for slow vertical saccades J Neurosci 71 247 256
44. M Mühlau A Weindl AM Wohlschläger C Gaser M Städtler M Valet C Zimmer J Kassubek A Peinemann 2007 Voxel-based morphometry indicates relative preservation of the limbic prefrontal cortex in early Huntington disease J Neural Transm 114 367 372
45. DP Munoz PJ Istvan 1998 Lateral inhibitory interactions in the intermediate layers of the monkey superior colliculus J Neurophysiol 79 1193 1209
46. G Oepen P Clarenbach U Thoden 1981 Disturbance of eye movements in Huntington's chorea Arch Psychiatr Nervenkr 229 205 213
47. D Pélisson C Prablanc C Urquizar 1988 Vestibuloocular reflex inhibition and gaze saccade control characteristics during eye-head orientation in humans J Neurophysiol 59 997 1013
48. F Persichetti J Srinidhi L Kanaley P Ge RH Myers K D'Arrigo GT Barnes ME MacDonald JP Vonsattel JF Gusella ED Bird 1994 Huntington's disease CAG trinucleotide repeats in pathologically confirmed post-mortem brains Neurobiol Dis 1 159 166
49. C Pierrot-Deseilligny S Rivaud B Pillon E Fournier Y Agid 1989 Lateral visually-guided saccades in progressive supranuclear palsy Brain 112 471 487
50. C Pierrot-Deseilligny RM Müri T Nyffeler D Milea 2005 The role of the human dorsolateral prefrontal cortex in ocular motor behavior Ann NY Acad Sci 1039 239 251
51. S Quessy EG Freedman 2004 Electrical stimulation of rhesus monkey nucleus reticularis gigantocellularis-I. Characteristics of evoked head movements Exp Brain Res 156 342 356
52. FR Robinson JO Phillips AF Fuchs 1994 Coordination of gaze shifts in primates: brainstem inputs to neck and extraocular motoneuron pools J Comp Neurol 346 43 62
53. A Rosenblatt RR Brinkman KY Liang EW Almqvist RL Margolis CY Huang M Sherr ML Franz MH Abbott MR Hayden CA Ross 2001 Familial influence on age of onset among siblings with Huntington disease Am J Med Genet 105 399 403
54. A Rosenblatt MH Abbort LM Gourley JC Troncoso RL Margolis J Brandt C Ross 2003 Predictors of Neuropathological severity in 100 patients with Huntington's disease Annals of Neurology 54 488 493
55. AJ Rubin WM King KA Reinbold I Shoulson 1993 Quantitative longitudinal assessment of saccades in Huntington's disease J Clin Neuroophthalmol 13 59 66
56. JA Sharpe DH Zackon 1987 Senescent saccades Acta Otolaryngol (Stockh) 104 422 428
57. I Shoulson S Fahn 1979 Huntington's disease: clinical care and evaluation Neurology 29 1 3
58. N Smyrnis I Evdokimidis NC Stefanis TS Constantinidis D Avramopoulos C Theleritis C Paximadis C Efstratiadis G Kastrinakis CN Stefanis 2002 The antisaccade task in a sample of 2,006 young males. II. Effects of task parameters Exp Brain Res 147 53 63
59. RG Snell JC MacMillan JP Cheadle I Fenton LP Lazarou P Davies ME MacDonald JF Gusella PS Harper DJ Shaw 1993 Relationship between trinucleotide repeat expansion and phenotypic variation in Huntington's disease Nat Genet 4 393 397
60. JW Spooner SM Sakala RW Baloh 1980 Effect of aging on eye tracking Arch Neurol 37 575 576
61. JS Stahl 1999 Amplitude of human head movements associated with horizontal saccades Exp Brain Res 126 41 54
62. A Starr 1967 A disorder of rapid eye movements in Huntigton's chorea Brain 90 545 564
63. JR Tian DS Zee AG Lasker SE Folstein 1991 Saccades in Huntington's disease: predictive tracking and interaction between release of fixation and initiation of saccades Neurology 41 875 881
64. TT Tsai AG Lasker DS Zee 1995 Visual attention in Huntington's disease: the effect of cueing on saccade latencies and manual reaction times Neuropsychologia 33 1617 1626
65. JP Vonsattel M DiFiglia 1998 Huntington disease J Neuropathol Exp Neurol 57 369 384
66. JP Vonsattel RH Myers TJ Stevens RJ Ferrante ED Bird EP Richardson Jr 1985 Neuropathological classification of Huntington's disease J Neuropathol Exp Neurol 44 559 577
67. NS Wexler J Lorimer J Porter F Gomez C Moskowitz E Shackell K Marder G Penchaszadeh SA Roberts J Gayan D Brocklebank SS Cherny LR Cardon J Gray SR Dlouhy S Wiktorski ME Hodes PM Conneally JB Penney J Gusella JH Cha M Irizarry D Rosas S Hersch Z Hollingsworth M MacDonald AB Young JM Andresen DE Housman MM De Young E Bonilla T Stillings A Negrette SR Snodgrass MD Martinez-Jaurrieta MA Ramos-Arroyo J Bickham JS Ramos F Marshall I Shoulson GJ Rey A Feigin N Arnheim A Cevedo-Cruz L Acosta J Alvir K Fischbeck LM Thompson A Young L Dure CJ O'Brien J Paulsen A Brickman D Krch S Peery P Hogarth DS Higgins Jr B Landwehrmeyer 2004 Venezuelan kindreds reveal that genetic and environmental factors modulate Huntington's disease age of onset Proc Natl Acad Sci USA 101 3498 3503
68. SJ Wilson P Glue D Ball DJ Nutt 1993 Saccadic eye movement parameters in normal subjects Electroencephalogr Clin Neurophysiol 86 69 74
69. CT Winograd-Gurvich N Georgiou-Karistianis A Evans L Millist JL Bradshaw A Churchyard E Chiu OB White 2003 Hypometric primary saccades and increased variability in visually-guided saccades in Huntington's disease Neuropsychologia 41 1683 1692
70. RC Wolf N Vasic C Schönfeldt-Lecuona GB Landwehrmeyer D Ecker 2007 Dorsolateral prefrontal cortex dysfunction in presymptomatic Huntington's disease: evidence from event-related fMRI Brain 130 2845 2857
71. WH Zangemeister A Mueller-Jensen 1985 The co-ordination of gaze movements in Huntington's disease Neuro-ophthalmology 5 193 206