Identification of an oculomotor biomarker of preclinical Huntington disease

Neurology

Volumn 67, Issue 3, 2006, Pages 485-487

  Golding, C V P ^a   Danchaivijitr, C ^a   Hodgson, T L ^b   Tabrizi, S J ^c   Kennard, C ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF EXETER   (United Kingdom)

^c NATIONAL HOSPITAL FOR NEUROLOGY AND NEUROSURGERY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CORNEA REFLEX; DISEASE COURSE; EYE MOVEMENT CONTROL; FEMALE; GENETICS; HUMAN; HUNTINGTON CHOREA; MALE; PRIORITY JOURNAL; SACCADIC EYE MOVEMENT; VOLUNTARY MOVEMENT;

ADULT; BIOLOGICAL MARKERS; DISEASE PROGRESSION; FEMALE; HUMANS; HUNTINGTON DISEASE; MALE; MIDDLE AGED; OCULAR MOTILITY DISORDERS; SACCADES;

EID: 33747048667     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/01.wnl.0000218215.43328.88     Document Type: Article

References (10)

1. Lasker AG, Zee DS. Ocular motor abnormalities in Huntington's disease. Vision Res 1997;37:3639-3645.
2. Blekher TM, Yee RD, Kirkwood SC, et al. Oculomotor control in asymptomatic and recently diagnosed individuals with the genetic marker for Huntington's disease. Vis Res 2004;44:2729-2736.
3. Shoulson I, Fahn S. Huntington disease: clinical care and evaluation. Neurology 1979;29:1-3.
4. Langbehn DR, Brinkman RR, Falush D, Paulsen JS, Hayden MR. International Huntington's Disease Collaborative Group. A new model for prediction of the age of onset and penetrance for Huntington's Disease based on CAG length. Clin Genet 2004;65:267-277.
5. Winograd-Gurvich CT, Georgiou-Karistianis N, Evans A, et al. Hypometric primary saccades and increased variability in visually-guided saccades in Huntington's disease. Neuropsychologia 2003;41:1683-1692.
6. Sanchez-Pernaute R, Garcia-Segura JM, del Barrio Alba A, Viano J, de Yebenes JG. Clinical correlation of striatal 1H MRS changes in Huntington's disease. Neurology 1999;53:806-812.
7. Mosimann UP, Muri RM, Burn DJ, Felblinger J, O'Brien JT, McKeith IG. Saccadic eye movement changes in Parkinson's disease dementia and dementia with Lewy bodies. Brain 2005;128(Pt 6):1267-1276.
8. Leigh RJ, Kennard C. Using saccades as a research tool in the clinical neurosciences. Brain 2004;127:460-477.
9. Brooks DJ, Andrews T. Imaging Huntington's disease. Chapter 4. In: Bates G, Harper P, Jones L, eds. Huntington's disease. Oxford: OUP, 2002:95-110.
10. Kori A, Miyashita N, Kato M, Hikosaka O, Usui S, Matsumura M. Eye movements in monkeys with local dopamine depletion in the caudate nucleus. II. Deficits in voluntary saccades. J Neurosci 1995;15:928-941.