메뉴 건너뛰기




Volumn 28, Issue 22, 2008, Pages 6877-6888

Translation initiation factor 2γ mutant alters start codon selection independent of Met-tRNA binding

Author keywords

[No Author keywords available]

Indexed keywords

GUANOSINE TRIPHOSPHATE; INITIATION FACTOR; METHIONINE; TRANSFER RNA; TRANSLATION INITIATION FACTOR 2 GAMMA; UNCLASSIFIED DRUG;

EID: 55849085351     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.01147-08     Document Type: Article
Times cited : (36)

References (33)
  • 1
    • 26944435515 scopus 로고    scopus 로고
    • Pi release from eIF2, not GTP hydrolysis, is the step controlled by start-site selection during eukaryotic translation initiation
    • Algire, M. A., D. Maag, and J. R. Lorsch. 2005. Pi release from eIF2, not GTP hydrolysis, is the step controlled by start-site selection during eukaryotic translation initiation. Mol. Cell 20:251-262.
    • (2005) Mol. Cell , vol.20 , pp. 251-262
    • Algire, M.A.1    Maag, D.2    Lorsch, J.R.3
  • 2
    • 33744957161 scopus 로고    scopus 로고
    • Direct binding of translation initiation factor eIF2γ-G domain to its GTPase-activating and GDP-GTP exchange factors eIF5 and eIF2Bε
    • Alone, P. V., and T. E. Dever. 2006. Direct binding of translation initiation factor eIF2γ-G domain to its GTPase-activating and GDP-GTP exchange factors eIF5 and eIF2Bε. J. Biol. Chem. 281:12636-12644.
    • (2006) J. Biol. Chem , vol.281 , pp. 12636-12644
    • Alone, P.V.1    Dever, T.E.2
  • 3
    • 0025234838 scopus 로고
    • Genetic characterization of the Saccharomyces cerevisiae translational initiation suppressors sui1, sui2 and SUI3 and their effects on HIS4 expression
    • Castilho-Valavicius, B., H. Yoon, and T. F. Donahue. 1990. Genetic characterization of the Saccharomyces cerevisiae translational initiation suppressors sui1, sui2 and SUI3 and their effects on HIS4 expression. Genetics 124:483-495.
    • (1990) Genetics , vol.124 , pp. 483-495
    • Castilho-Valavicius, B.1    Yoon, H.2    Donahue, T.F.3
  • 5
    • 0013112952 scopus 로고
    • Yeast translation initiation suppressor sui2 encodes the α subunit of eukaryotic initiation factor 2 and shares identity with the human α subunit
    • Cigan, A. M., E. K. Pabich, L. Feng, and T. F. Donahue. 1989. Yeast translation initiation suppressor sui2 encodes the α subunit of eukaryotic initiation factor 2 and shares identity with the human α subunit. Proc. Natl. Acad. Sci. USA 86:2784-2788.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 2784-2788
    • Cigan, A.M.1    Pabich, E.K.2    Feng, L.3    Donahue, T.F.4
  • 6
    • 0020564055 scopus 로고
    • Nucleotide pools of growing, synchronized and stressed cultures of Saccharomyces cerevisiae
    • Ditzelmuller, G., W. Wohrer, C. P. Kubicek, and M. Rohr. 1983. Nucleotide pools of growing, synchronized and stressed cultures of Saccharomyces cerevisiae. Arch. Microbiol. 135:63-67.
    • (1983) Arch. Microbiol , vol.135 , pp. 63-67
    • Ditzelmuller, G.1    Wohrer, W.2    Kubicek, C.P.3    Rohr, M.4
  • 7
    • 0002538063 scopus 로고    scopus 로고
    • Genetic approaches to translation initiation in Saccharomyces cerevisiae
    • N. Sonenberg, J. W. B. Hershey, and M. B. Mathews ed, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
    • Donahue, T. 2000. Genetic approaches to translation initiation in Saccharomyces cerevisiae, p. 487-502. In N. Sonenberg, J. W. B. Hershey, and M. B. Mathews (ed.), Translational control of gene expression. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
    • (2000) Translational control of gene expression , pp. 487-502
    • Donahue, T.1
  • 8
    • 0024297814 scopus 로고
    • Mutations at a Zn(II) finger motif in the yeast eIF-2β gene alter ribosomal start-site selection during the scanning process
    • Donahue, T. F., A. M. Cigan, E. K. Pabich, and B. Castilho- Valavicius. 1988. Mutations at a Zn(II) finger motif in the yeast eIF-2β gene alter ribosomal start-site selection during the scanning process. Cell 54:621-632.
    • (1988) Cell , vol.54 , pp. 621-632
    • Donahue, T.F.1    Cigan, A.M.2    Pabich, E.K.3    Castilho- Valavicius, B.4
  • 9
    • 0029022224 scopus 로고
    • Mutations in GCD11, the structural gene for eIF-2γ in yeast, alter translational regulation of GCN4 and the selection of the start site for protein synthesis
    • Dorris, D. R., F. L. Erickson, and E. M. Hannig. 1995. Mutations in GCD11, the structural gene for eIF-2γ in yeast, alter translational regulation of GCN4 and the selection of the start site for protein synthesis. EMBO J. 14:2239-2249.
    • (1995) EMBO J , vol.14 , pp. 2239-2249
    • Dorris, D.R.1    Erickson, F.L.2    Hannig, E.M.3
  • 10
    • 0029858531 scopus 로고    scopus 로고
    • Ligand interactions with eukaryotic translation initiation factor 2: Role of the γ-subunit
    • Erickson, F. L., and E. M. Hannig. 1996. Ligand interactions with eukaryotic translation initiation factor 2: role of the γ-subunit. EMBO J. 15:6311-6320.
    • (1996) EMBO J , vol.15 , pp. 6311-6320
    • Erickson, F.L.1    Hannig, E.M.2
  • 11
    • 0041589832 scopus 로고    scopus 로고
    • The yeast eukaryotic initiation factor 4G (eIF4G) HEAT domain interacts with eIF1 and eIF5 and is involved in stringent AUG selection
    • He, H., T. von der Haar, C. R. Singh, M. Ii, B. Li, A. G. Hinnebusch, J. E. McCarthy, and K. Asano. 2003. The yeast eukaryotic initiation factor 4G (eIF4G) HEAT domain interacts with eIF1 and eIF5 and is involved in stringent AUG selection. Mol. Cell. Biol. 23:5431-5445.
    • (2003) Mol. Cell. Biol , vol.23 , pp. 5431-5445
    • He, H.1    von der Haar, T.2    Singh, C.R.3    Ii, M.4    Li, B.5    Hinnebusch, A.G.6    McCarthy, J.E.7    Asano, K.8
  • 12
    • 0000091608 scopus 로고    scopus 로고
    • Pathway and mechanism of initiation of protein synthesis
    • N. Sonenberg, J. W. B. Hershey, and M. B. Mathews ed, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
    • Hershey, J. W. B., and W. C. Merrick. 2000. Pathway and mechanism of initiation of protein synthesis, p. 33-88. In N. Sonenberg, J. W. B. Hershey, and M. B. Mathews (ed.), Translational control of gene expression. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
    • (2000) Translational control of gene expression , pp. 33-88
    • Hershey, J.W.B.1    Merrick, W.C.2
  • 13
    • 0002470681 scopus 로고    scopus 로고
    • Mechanism and regulation of initiator methionyl-tRNA binding to ribosomes
    • N. Sonenberg, J. W. B. Hershey, and M. B. Mathews ed, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
    • Hinnebusch, A. G. 2000. Mechanism and regulation of initiator methionyl-tRNA binding to ribosomes, p. 185-243. In N. Sonenberg, J. W. B. Hershey, and M. B. Mathews (ed.), Translational control of gene expression. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
    • (2000) Translational control of gene expression , pp. 185-243
    • Hinnebusch, A.G.1
  • 14
    • 27144510561 scopus 로고    scopus 로고
    • Translational regulation of GCN4 and the general amino acid control of yeast
    • Hinnebusch, A. G. 2005. Translational regulation of GCN4 and the general amino acid control of yeast. Annu. Rev. Microbiol. 59:407-450.
    • (2005) Annu. Rev. Microbiol , vol.59 , pp. 407-450
    • Hinnebusch, A.G.1
  • 15
    • 0030886675 scopus 로고    scopus 로고
    • GTP hydrolysis controls stringent selection of the AUG start codon during translation initiation in Saccharomyces cerevisiae
    • Huang, H., H. Yoon, E. M. Hannig, and T. F. Donahue. 1997. GTP hydrolysis controls stringent selection of the AUG start codon during translation initiation in Saccharomyces cerevisiae. Genes Dev. 11:2396-2413.
    • (1997) Genes Dev , vol.11 , pp. 2396-2413
    • Huang, H.1    Yoon, H.2    Hannig, E.M.3    Donahue, T.F.4
  • 16
    • 0347123543 scopus 로고    scopus 로고
    • GTP-dependent recognition of the methionine moiety on initiator tRNA by translation factor eIF2
    • Kapp, L. D., and J. R. Lorsch. 2004. GTP-dependent recognition of the methionine moiety on initiator tRNA by translation factor eIF2. J. Mol. Biol. 335:923-936.
    • (2004) J. Mol. Biol , vol.335 , pp. 923-936
    • Kapp, L.D.1    Lorsch, J.R.2
  • 17
    • 0345305759 scopus 로고    scopus 로고
    • Position of eukaryotic initiation factor eIF1 on the 40S ribosomal subunit determined by directed hydroxyl radical probing
    • Lomakin, I. B., V. G. Kolupaeva, A. Marintchev, G. Wagner, and T. V. Pestova. 2003. Position of eukaryotic initiation factor eIF1 on the 40S ribosomal subunit determined by directed hydroxyl radical probing. Genes Dev. 17:2786-2797.
    • (2003) Genes Dev , vol.17 , pp. 2786-2797
    • Lomakin, I.B.1    Kolupaeva, V.G.2    Marintchev, A.3    Wagner, G.4    Pestova, T.V.5
  • 18
    • 12344314307 scopus 로고    scopus 로고
    • A conformational change in the eukaryotic translation preinitiation complex and release of eIF1 signal recognition of the start codon
    • Maag, D., C. A. Fekete, Z. Gryczynski, and J. R. Lorsch. 2005. A conformational change in the eukaryotic translation preinitiation complex and release of eIF1 signal recognition of the start codon. Mol. Cell 17:265-275.
    • (2005) Mol. Cell , vol.17 , pp. 265-275
    • Maag, D.1    Fekete, C.A.2    Gryczynski, Z.3    Lorsch, J.R.4
  • 19
    • 0026320245 scopus 로고
    • Association of RAP1 binding sites with stringent control of ribosomal protein gene transcription in Saccharomyces cerevisiae
    • Moehle, C. M., and A. G. Hinnebusch. 1991. Association of RAP1 binding sites with stringent control of ribosomal protein gene transcription in Saccharomyces cerevisiae. Mol. Cell. Biol. 11:2723-2735.
    • (1991) Mol. Cell. Biol , vol.11 , pp. 2723-2735
    • Moehle, C.M.1    Hinnebusch, A.G.2
  • 22
    • 0032572776 scopus 로고    scopus 로고
    • Eukaryotic ribosomes require initiation factors 1 and 1A to locate initiation codons
    • Pestova, T. V., S. I. Borukhov, and C. U. T. Hellen. 1998. Eukaryotic ribosomes require initiation factors 1 and 1A to locate initiation codons. Nature 394:854-859.
    • (1998) Nature , vol.394 , pp. 854-859
    • Pestova, T.V.1    Borukhov, S.I.2    Hellen, C.U.T.3
  • 24
    • 1642304746 scopus 로고    scopus 로고
    • X-ray structure of translation initiation factor eIF2γ: Implications for tRNA and eIF2α binding
    • Roll-Mecak, A., P. Alone, C. Cao, T. E. Dever, and S. K. Burley. 2004. X-ray structure of translation initiation factor eIF2γ: implications for tRNA and eIF2α binding. J. Biol. Chem. 279:10634-10642.
    • (2004) J. Biol. Chem , vol.279 , pp. 10634-10642
    • Roll-Mecak, A.1    Alone, P.2    Cao, C.3    Dever, T.E.4    Burley, S.K.5
  • 25
    • 0037007203 scopus 로고    scopus 로고
    • The large subunit of initiation factor aIF2 is a close structural homologue of elongation factors
    • Schmitt, E., S. Blanquet, and Y. Mechulam. 2002. The large subunit of initiation factor aIF2 is a close structural homologue of elongation factors. EMBO J. 21:1821-1832.
    • (2002) EMBO J , vol.21 , pp. 1821-1832
    • Schmitt, E.1    Blanquet, S.2    Mechulam, Y.3
  • 26
    • 33847224854 scopus 로고    scopus 로고
    • Intragenic suppressor mutations restore GTPase and translation functions of a eukaryotic initiation factor 5B switch II mutant
    • Shin, B. S., M. G. Acker, D. Maag, J. R. Kim, J. R. Lorsch, and T. E. Dever. 2007. Intragenic suppressor mutations restore GTPase and translation functions of a eukaryotic initiation factor 5B switch II mutant. Mol. Cell. Biol. 27:1677-1685.
    • (2007) Mol. Cell. Biol , vol.27 , pp. 1677-1685
    • Shin, B.S.1    Acker, M.G.2    Maag, D.3    Kim, J.R.4    Lorsch, J.R.5    Dever, T.E.6
  • 27
    • 0030920782 scopus 로고    scopus 로고
    • G protein mechanisms: Insights from structural analysis
    • Sprang, S. R. 1997. G protein mechanisms: insights from structural analysis. Annu. Rev. Biochem. 66:639-678.
    • (1997) Annu. Rev. Biochem , vol.66 , pp. 639-678
    • Sprang, S.R.1
  • 28
    • 10644249220 scopus 로고    scopus 로고
    • Release of initiation factors from 48S complexes during ribosomal subunit joining and the link between establishment of codon-anticodon base-pairing and hydrolysis of eIF2-bound GTP
    • Unbehaun, A., S. I. Borukhov, C. U. Hellen, and T. V. Pestova. 2004. Release of initiation factors from 48S complexes during ribosomal subunit joining and the link between establishment of codon-anticodon base-pairing and hydrolysis of eIF2-bound GTP. Genes Dev. 18:3078-3093.
    • (2004) Genes Dev , vol.18 , pp. 3078-3093
    • Unbehaun, A.1    Borukhov, S.I.2    Hellen, C.U.3    Pestova, T.V.4
  • 29
    • 6344291066 scopus 로고    scopus 로고
    • Interactions of eukaryotic translation initiation factor 3 (eIF3) subunit NIP1/c with eIF1 and eIF5 promote preinitiation complex assembly and regulate start codon selection
    • Valasek, L., K. H. Nielsen, F. Zhang, C. A. Fekete, and A. G. Hinnebusch. 2004. Interactions of eukaryotic translation initiation factor 3 (eIF3) subunit NIP1/c with eIF1 and eIF5 promote preinitiation complex assembly and regulate start codon selection. Mol. Cell. Biol. 24:9437-9455.
    • (2004) Mol. Cell. Biol , vol.24 , pp. 9437-9455
    • Valasek, L.1    Nielsen, K.H.2    Zhang, F.3    Fekete, C.A.4    Hinnebusch, A.G.5
  • 30
    • 0035834388 scopus 로고    scopus 로고
    • The guanine nucleotide-binding switch in three dimensions
    • Vetter, I. R., and A. Wittinghofer. 2001. The guanine nucleotide-binding switch in three dimensions. Science 294:1299-1304.
    • (2001) Science , vol.294 , pp. 1299-1304
    • Vetter, I.R.1    Wittinghofer, A.2
  • 31
    • 0024343499 scopus 로고
    • Mutations in the structural genes for eukaryotic initiation factors 2α and 2β of Saccharomyces cerevisiae disrupt translational control of GCN4 mRNA
    • Williams, N. P., A. G. Hinnebusch, and T. F. Donahue. 1989. Mutations in the structural genes for eukaryotic initiation factors 2α and 2β of Saccharomyces cerevisiae disrupt translational control of GCN4 mRNA. Proc. Natl. Acad. Sci. USA 86:7515-7519.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 7515-7519
    • Williams, N.P.1    Hinnebusch, A.G.2    Donahue, T.F.3
  • 32
    • 36749037829 scopus 로고    scopus 로고
    • Structure of an archaeal heterotrimeric initiation factor 2 reveals a nucleotide state between the GTP and the GDP states
    • Yatime, L., Y. Mechulam, S. Blanquet, and E. Schmitt. 2007. Structure of an archaeal heterotrimeric initiation factor 2 reveals a nucleotide state between the GTP and the GDP states. Proc. Natl. Acad. Sci. USA 104:18445-18450.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 18445-18450
    • Yatime, L.1    Mechulam, Y.2    Blanquet, S.3    Schmitt, E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.