-
1
-
-
26944435515
-
Pi release from eIF2, not GTP hydrolysis, is the step controlled by start-site selection during eukaryotic translation initiation
-
Algire, M. A., D. Maag, and J. R. Lorsch. 2005. Pi release from eIF2, not GTP hydrolysis, is the step controlled by start-site selection during eukaryotic translation initiation. Mol. Cell 20:251-262.
-
(2005)
Mol. Cell
, vol.20
, pp. 251-262
-
-
Algire, M.A.1
Maag, D.2
Lorsch, J.R.3
-
2
-
-
33744957161
-
Direct binding of translation initiation factor eIF2γ-G domain to its GTPase-activating and GDP-GTP exchange factors eIF5 and eIF2Bε
-
Alone, P. V., and T. E. Dever. 2006. Direct binding of translation initiation factor eIF2γ-G domain to its GTPase-activating and GDP-GTP exchange factors eIF5 and eIF2Bε. J. Biol. Chem. 281:12636-12644.
-
(2006)
J. Biol. Chem
, vol.281
, pp. 12636-12644
-
-
Alone, P.V.1
Dever, T.E.2
-
3
-
-
0025234838
-
Genetic characterization of the Saccharomyces cerevisiae translational initiation suppressors sui1, sui2 and SUI3 and their effects on HIS4 expression
-
Castilho-Valavicius, B., H. Yoon, and T. F. Donahue. 1990. Genetic characterization of the Saccharomyces cerevisiae translational initiation suppressors sui1, sui2 and SUI3 and their effects on HIS4 expression. Genetics 124:483-495.
-
(1990)
Genetics
, vol.124
, pp. 483-495
-
-
Castilho-Valavicius, B.1
Yoon, H.2
Donahue, T.F.3
-
4
-
-
34249069609
-
Dissociation of eIF1 from the 40S ribosomal subunit is a key step in start codon selection in vivo
-
Cheung, Y. N., D. Maag, S. F. Mitchell, C. A. Fekete, M. A. Algire, J. E. Takacs, N. Shirokikh, T. Pestova, J. R. Lorsch, and A. G. Hinnebusch. 2007. Dissociation of eIF1 from the 40S ribosomal subunit is a key step in start codon selection in vivo. Genes Dev. 21:1217-1230.
-
(2007)
Genes Dev
, vol.21
, pp. 1217-1230
-
-
Cheung, Y.N.1
Maag, D.2
Mitchell, S.F.3
Fekete, C.A.4
Algire, M.A.5
Takacs, J.E.6
Shirokikh, N.7
Pestova, T.8
Lorsch, J.R.9
Hinnebusch, A.G.10
-
5
-
-
0013112952
-
Yeast translation initiation suppressor sui2 encodes the α subunit of eukaryotic initiation factor 2 and shares identity with the human α subunit
-
Cigan, A. M., E. K. Pabich, L. Feng, and T. F. Donahue. 1989. Yeast translation initiation suppressor sui2 encodes the α subunit of eukaryotic initiation factor 2 and shares identity with the human α subunit. Proc. Natl. Acad. Sci. USA 86:2784-2788.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 2784-2788
-
-
Cigan, A.M.1
Pabich, E.K.2
Feng, L.3
Donahue, T.F.4
-
6
-
-
0020564055
-
Nucleotide pools of growing, synchronized and stressed cultures of Saccharomyces cerevisiae
-
Ditzelmuller, G., W. Wohrer, C. P. Kubicek, and M. Rohr. 1983. Nucleotide pools of growing, synchronized and stressed cultures of Saccharomyces cerevisiae. Arch. Microbiol. 135:63-67.
-
(1983)
Arch. Microbiol
, vol.135
, pp. 63-67
-
-
Ditzelmuller, G.1
Wohrer, W.2
Kubicek, C.P.3
Rohr, M.4
-
7
-
-
0002538063
-
Genetic approaches to translation initiation in Saccharomyces cerevisiae
-
N. Sonenberg, J. W. B. Hershey, and M. B. Mathews ed, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
-
Donahue, T. 2000. Genetic approaches to translation initiation in Saccharomyces cerevisiae, p. 487-502. In N. Sonenberg, J. W. B. Hershey, and M. B. Mathews (ed.), Translational control of gene expression. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
-
(2000)
Translational control of gene expression
, pp. 487-502
-
-
Donahue, T.1
-
8
-
-
0024297814
-
Mutations at a Zn(II) finger motif in the yeast eIF-2β gene alter ribosomal start-site selection during the scanning process
-
Donahue, T. F., A. M. Cigan, E. K. Pabich, and B. Castilho- Valavicius. 1988. Mutations at a Zn(II) finger motif in the yeast eIF-2β gene alter ribosomal start-site selection during the scanning process. Cell 54:621-632.
-
(1988)
Cell
, vol.54
, pp. 621-632
-
-
Donahue, T.F.1
Cigan, A.M.2
Pabich, E.K.3
Castilho- Valavicius, B.4
-
9
-
-
0029022224
-
Mutations in GCD11, the structural gene for eIF-2γ in yeast, alter translational regulation of GCN4 and the selection of the start site for protein synthesis
-
Dorris, D. R., F. L. Erickson, and E. M. Hannig. 1995. Mutations in GCD11, the structural gene for eIF-2γ in yeast, alter translational regulation of GCN4 and the selection of the start site for protein synthesis. EMBO J. 14:2239-2249.
-
(1995)
EMBO J
, vol.14
, pp. 2239-2249
-
-
Dorris, D.R.1
Erickson, F.L.2
Hannig, E.M.3
-
10
-
-
0029858531
-
Ligand interactions with eukaryotic translation initiation factor 2: Role of the γ-subunit
-
Erickson, F. L., and E. M. Hannig. 1996. Ligand interactions with eukaryotic translation initiation factor 2: role of the γ-subunit. EMBO J. 15:6311-6320.
-
(1996)
EMBO J
, vol.15
, pp. 6311-6320
-
-
Erickson, F.L.1
Hannig, E.M.2
-
11
-
-
0041589832
-
The yeast eukaryotic initiation factor 4G (eIF4G) HEAT domain interacts with eIF1 and eIF5 and is involved in stringent AUG selection
-
He, H., T. von der Haar, C. R. Singh, M. Ii, B. Li, A. G. Hinnebusch, J. E. McCarthy, and K. Asano. 2003. The yeast eukaryotic initiation factor 4G (eIF4G) HEAT domain interacts with eIF1 and eIF5 and is involved in stringent AUG selection. Mol. Cell. Biol. 23:5431-5445.
-
(2003)
Mol. Cell. Biol
, vol.23
, pp. 5431-5445
-
-
He, H.1
von der Haar, T.2
Singh, C.R.3
Ii, M.4
Li, B.5
Hinnebusch, A.G.6
McCarthy, J.E.7
Asano, K.8
-
12
-
-
0000091608
-
Pathway and mechanism of initiation of protein synthesis
-
N. Sonenberg, J. W. B. Hershey, and M. B. Mathews ed, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
-
Hershey, J. W. B., and W. C. Merrick. 2000. Pathway and mechanism of initiation of protein synthesis, p. 33-88. In N. Sonenberg, J. W. B. Hershey, and M. B. Mathews (ed.), Translational control of gene expression. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
-
(2000)
Translational control of gene expression
, pp. 33-88
-
-
Hershey, J.W.B.1
Merrick, W.C.2
-
13
-
-
0002470681
-
Mechanism and regulation of initiator methionyl-tRNA binding to ribosomes
-
N. Sonenberg, J. W. B. Hershey, and M. B. Mathews ed, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
-
Hinnebusch, A. G. 2000. Mechanism and regulation of initiator methionyl-tRNA binding to ribosomes, p. 185-243. In N. Sonenberg, J. W. B. Hershey, and M. B. Mathews (ed.), Translational control of gene expression. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
-
(2000)
Translational control of gene expression
, pp. 185-243
-
-
Hinnebusch, A.G.1
-
14
-
-
27144510561
-
Translational regulation of GCN4 and the general amino acid control of yeast
-
Hinnebusch, A. G. 2005. Translational regulation of GCN4 and the general amino acid control of yeast. Annu. Rev. Microbiol. 59:407-450.
-
(2005)
Annu. Rev. Microbiol
, vol.59
, pp. 407-450
-
-
Hinnebusch, A.G.1
-
15
-
-
0030886675
-
GTP hydrolysis controls stringent selection of the AUG start codon during translation initiation in Saccharomyces cerevisiae
-
Huang, H., H. Yoon, E. M. Hannig, and T. F. Donahue. 1997. GTP hydrolysis controls stringent selection of the AUG start codon during translation initiation in Saccharomyces cerevisiae. Genes Dev. 11:2396-2413.
-
(1997)
Genes Dev
, vol.11
, pp. 2396-2413
-
-
Huang, H.1
Yoon, H.2
Hannig, E.M.3
Donahue, T.F.4
-
16
-
-
0347123543
-
GTP-dependent recognition of the methionine moiety on initiator tRNA by translation factor eIF2
-
Kapp, L. D., and J. R. Lorsch. 2004. GTP-dependent recognition of the methionine moiety on initiator tRNA by translation factor eIF2. J. Mol. Biol. 335:923-936.
-
(2004)
J. Mol. Biol
, vol.335
, pp. 923-936
-
-
Kapp, L.D.1
Lorsch, J.R.2
-
17
-
-
0345305759
-
Position of eukaryotic initiation factor eIF1 on the 40S ribosomal subunit determined by directed hydroxyl radical probing
-
Lomakin, I. B., V. G. Kolupaeva, A. Marintchev, G. Wagner, and T. V. Pestova. 2003. Position of eukaryotic initiation factor eIF1 on the 40S ribosomal subunit determined by directed hydroxyl radical probing. Genes Dev. 17:2786-2797.
-
(2003)
Genes Dev
, vol.17
, pp. 2786-2797
-
-
Lomakin, I.B.1
Kolupaeva, V.G.2
Marintchev, A.3
Wagner, G.4
Pestova, T.V.5
-
18
-
-
12344314307
-
A conformational change in the eukaryotic translation preinitiation complex and release of eIF1 signal recognition of the start codon
-
Maag, D., C. A. Fekete, Z. Gryczynski, and J. R. Lorsch. 2005. A conformational change in the eukaryotic translation preinitiation complex and release of eIF1 signal recognition of the start codon. Mol. Cell 17:265-275.
-
(2005)
Mol. Cell
, vol.17
, pp. 265-275
-
-
Maag, D.1
Fekete, C.A.2
Gryczynski, Z.3
Lorsch, J.R.4
-
19
-
-
0026320245
-
Association of RAP1 binding sites with stringent control of ribosomal protein gene transcription in Saccharomyces cerevisiae
-
Moehle, C. M., and A. G. Hinnebusch. 1991. Association of RAP1 binding sites with stringent control of ribosomal protein gene transcription in Saccharomyces cerevisiae. Mol. Cell. Biol. 11:2723-2735.
-
(1991)
Mol. Cell. Biol
, vol.11
, pp. 2723-2735
-
-
Moehle, C.M.1
Hinnebusch, A.G.2
-
20
-
-
0028812785
-
Phe, EF-Tu, and a GTP analog
-
Phe, EF-Tu, and a GTP analog. Science 270:1464- 1472.
-
(1995)
Science
, vol.270
, pp. 1464-1472
-
-
Nissen, P.1
Kjeldgaard, M.2
Thirup, S.3
Polekhina, G.4
Reshetnikova, L.5
Clark, B.F.6
Nyborg, J.7
-
21
-
-
34047263278
-
The eukaryotic translation initiation factors eIF1 and eIF1A induce an open conformation of the 40S ribosome
-
Passmore, L. A., T. M. Schmeing, D. Maag, D. J. Applefield, M. G. Acker, M. A. Algire, J. R. Lorsch, and V. Ramakrishnan. 2007. The eukaryotic translation initiation factors eIF1 and eIF1A induce an open conformation of the 40S ribosome. Mol. Cell 26:41-50.
-
(2007)
Mol. Cell
, vol.26
, pp. 41-50
-
-
Passmore, L.A.1
Schmeing, T.M.2
Maag, D.3
Applefield, D.J.4
Acker, M.G.5
Algire, M.A.6
Lorsch, J.R.7
Ramakrishnan, V.8
-
22
-
-
0032572776
-
Eukaryotic ribosomes require initiation factors 1 and 1A to locate initiation codons
-
Pestova, T. V., S. I. Borukhov, and C. U. T. Hellen. 1998. Eukaryotic ribosomes require initiation factors 1 and 1A to locate initiation codons. Nature 394:854-859.
-
(1998)
Nature
, vol.394
, pp. 854-859
-
-
Pestova, T.V.1
Borukhov, S.I.2
Hellen, C.U.T.3
-
23
-
-
0030587857
-
Helix unwinding in the effector region of elongation factor EF-Tu-GDP
-
Polekhina, G., S. Thirup, M. Kjeldgaard, P. Nissen, C. Lippmann, and J. Nyborg. 1996. Helix unwinding in the effector region of elongation factor EF-Tu-GDP. Structure 4:1141-1151.
-
(1996)
Structure
, vol.4
, pp. 1141-1151
-
-
Polekhina, G.1
Thirup, S.2
Kjeldgaard, M.3
Nissen, P.4
Lippmann, C.5
Nyborg, J.6
-
24
-
-
1642304746
-
X-ray structure of translation initiation factor eIF2γ: Implications for tRNA and eIF2α binding
-
Roll-Mecak, A., P. Alone, C. Cao, T. E. Dever, and S. K. Burley. 2004. X-ray structure of translation initiation factor eIF2γ: implications for tRNA and eIF2α binding. J. Biol. Chem. 279:10634-10642.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 10634-10642
-
-
Roll-Mecak, A.1
Alone, P.2
Cao, C.3
Dever, T.E.4
Burley, S.K.5
-
25
-
-
0037007203
-
The large subunit of initiation factor aIF2 is a close structural homologue of elongation factors
-
Schmitt, E., S. Blanquet, and Y. Mechulam. 2002. The large subunit of initiation factor aIF2 is a close structural homologue of elongation factors. EMBO J. 21:1821-1832.
-
(2002)
EMBO J
, vol.21
, pp. 1821-1832
-
-
Schmitt, E.1
Blanquet, S.2
Mechulam, Y.3
-
26
-
-
33847224854
-
Intragenic suppressor mutations restore GTPase and translation functions of a eukaryotic initiation factor 5B switch II mutant
-
Shin, B. S., M. G. Acker, D. Maag, J. R. Kim, J. R. Lorsch, and T. E. Dever. 2007. Intragenic suppressor mutations restore GTPase and translation functions of a eukaryotic initiation factor 5B switch II mutant. Mol. Cell. Biol. 27:1677-1685.
-
(2007)
Mol. Cell. Biol
, vol.27
, pp. 1677-1685
-
-
Shin, B.S.1
Acker, M.G.2
Maag, D.3
Kim, J.R.4
Lorsch, J.R.5
Dever, T.E.6
-
27
-
-
0030920782
-
G protein mechanisms: Insights from structural analysis
-
Sprang, S. R. 1997. G protein mechanisms: insights from structural analysis. Annu. Rev. Biochem. 66:639-678.
-
(1997)
Annu. Rev. Biochem
, vol.66
, pp. 639-678
-
-
Sprang, S.R.1
-
28
-
-
10644249220
-
Release of initiation factors from 48S complexes during ribosomal subunit joining and the link between establishment of codon-anticodon base-pairing and hydrolysis of eIF2-bound GTP
-
Unbehaun, A., S. I. Borukhov, C. U. Hellen, and T. V. Pestova. 2004. Release of initiation factors from 48S complexes during ribosomal subunit joining and the link between establishment of codon-anticodon base-pairing and hydrolysis of eIF2-bound GTP. Genes Dev. 18:3078-3093.
-
(2004)
Genes Dev
, vol.18
, pp. 3078-3093
-
-
Unbehaun, A.1
Borukhov, S.I.2
Hellen, C.U.3
Pestova, T.V.4
-
29
-
-
6344291066
-
Interactions of eukaryotic translation initiation factor 3 (eIF3) subunit NIP1/c with eIF1 and eIF5 promote preinitiation complex assembly and regulate start codon selection
-
Valasek, L., K. H. Nielsen, F. Zhang, C. A. Fekete, and A. G. Hinnebusch. 2004. Interactions of eukaryotic translation initiation factor 3 (eIF3) subunit NIP1/c with eIF1 and eIF5 promote preinitiation complex assembly and regulate start codon selection. Mol. Cell. Biol. 24:9437-9455.
-
(2004)
Mol. Cell. Biol
, vol.24
, pp. 9437-9455
-
-
Valasek, L.1
Nielsen, K.H.2
Zhang, F.3
Fekete, C.A.4
Hinnebusch, A.G.5
-
30
-
-
0035834388
-
The guanine nucleotide-binding switch in three dimensions
-
Vetter, I. R., and A. Wittinghofer. 2001. The guanine nucleotide-binding switch in three dimensions. Science 294:1299-1304.
-
(2001)
Science
, vol.294
, pp. 1299-1304
-
-
Vetter, I.R.1
Wittinghofer, A.2
-
31
-
-
0024343499
-
Mutations in the structural genes for eukaryotic initiation factors 2α and 2β of Saccharomyces cerevisiae disrupt translational control of GCN4 mRNA
-
Williams, N. P., A. G. Hinnebusch, and T. F. Donahue. 1989. Mutations in the structural genes for eukaryotic initiation factors 2α and 2β of Saccharomyces cerevisiae disrupt translational control of GCN4 mRNA. Proc. Natl. Acad. Sci. USA 86:7515-7519.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 7515-7519
-
-
Williams, N.P.1
Hinnebusch, A.G.2
Donahue, T.F.3
-
32
-
-
36749037829
-
Structure of an archaeal heterotrimeric initiation factor 2 reveals a nucleotide state between the GTP and the GDP states
-
Yatime, L., Y. Mechulam, S. Blanquet, and E. Schmitt. 2007. Structure of an archaeal heterotrimeric initiation factor 2 reveals a nucleotide state between the GTP and the GDP states. Proc. Natl. Acad. Sci. USA 104:18445-18450.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 18445-18450
-
-
Yatime, L.1
Mechulam, Y.2
Blanquet, S.3
Schmitt, E.4
|