Constant expression of hexose-6-phosphate dehydrogenase during differentiation of human adipose-derived mesenchymal stem cells

Journal of Molecular Endocrinology

Volumn 41, Issue 3-4, 2008, Pages 125-133

  Senesi, Silvia ^a   Marcolongo, Paola ^a   Manini, Ivana ^a   Fulceri, Rosella ^a   Sorrentino, Vincenzo ^a   Csala, Miklós ^b,c   Bánhegyi, Gábor ^a,b,c   Benedetti, Angelo ^a  

^a UNIVERSITY OF SIENA   (Italy)

^b SEMMELWEIS UNIVERSITY   (Hungary)

^c INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE; GLUCOSE 6 PHOSPHATE DEHYDROGENASE;

ADIPOGENESIS; ADIPOSE TISSUE CELL; ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL STRAIN 3T3; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MESENCHYMAL STEM CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1; 3T3-L1 CELLS; ADIPOGENESIS; ADIPOSE TISSUE; ANIMALS; CARBOHYDRATE DEHYDROGENASES; CELL DIFFERENTIATION; CELL LINEAGE; CORTISONE; CORTISONE REDUCTASE; ENZYME INDUCTION; HUMANS; HYDROCORTISONE; MESENCHYMAL STEM CELLS; MICE; OXIDATION-REDUCTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 55749111677     PISSN: 09525041     EISSN: None     Source Type: Journal    
DOI: 10.1677/JME-08-0028     Document Type: Article

References (44)

1. Andrew R, Westerbacka J, Wahren J, Yki-Jarvinen H & Walker BR 2005 The contribution of visceral adipose tissue to splanchnic cortisol production in healthy humans. Diabetes 54 1364-1370.
2. Atanasov AG, Nashev LG, Schweizer RA, Frick C & Odermait A 2004 Hexose-6-phosphate dehydrogenase determines the reaction direction of 11β-hydroxysteroid dehydrogenase type 1 as an oxoreductase. FEBS Letters 571 129-133.
3. Bánhegyi G, Benedetti A, Fulceri R & Senesi S 2004 Cooperativity between 11β-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase in the lumen of the endoplasmic reticulum. Journal of Biological Chemistry 279 27017-27021.
4. Belkaid A, Copland IB, Massillon D & Annabi B 2006a Silencing of the human microsomal glucose-6-phosphate translocase induces glioma cell death: potential new anticancer target for curcumin. FEBS Letters 580 3746-3752.
5. Belkaid A, Currie J-C, Desgagnés J & Annabi B 2006b The chemopreventive properties of chlorogenic acid reveal a potential new role for the microsomal glucose-6-phosphate translocase in brain tumor progression. Cancer Cell International 6 7.
6. Brem AS, Bina RB, King TC & Morris DJ 1998 Localization of 2 11β-OH steroid dehydrogenase isoforms in aortic endothelial cells. Hypertension 31 459-462.
7. Buetler E & Morrison M 1967 Localization and characteristics of hexose 6-phosphate dehydrogenase (glucose dehydrogenase). Journal of Biological Chemistry 242 5280-5293.
8. Bujalska IJ, Walker EA, Hewison M & Stewart PM 2002 A switch in dehydrogenase to reductase activity of 11β-hydroxys teroid dehydrogenase type 1 upon differentiation of human omental adipose stromal cells. Journal of Clinical Endocrinology and Metabolism 87 1205-1210.
9. Bujalska IJ, Druper N, Michailidou Z, Tomlinson JW, White PC, Chapman KE, Walker EA & Stewart PM 2005 Hexose-6-phosphate dehydrogenase confers oxo-reductase activity upon 11β-hydroxysteroid dehydrogenase type 1. Journal of Molecular Endocrinology 34 675-684.
10. Bujalska IJ, Gathercole LL, Tomlinson JW, Darimont C, Ermolieff J, Fanjul AN, Rejto PA & Stewart PM 2008 A novel selective 11β-hydroxysteroid dehydrogenase type 1 inhibitor prevents human adipogenesis. Journal of Endocrinology 197 297-307.
11. Burchell A, Jung RT, Lang CC, Bennet W & Shepherd AN 1987 Diagnosis of type 1a and type 1c glycogen storage diseases in adults. Lancet 9 1059-1062.
12. Clarke JL & Mason PJ 2003 Murine hexose-6-phosphate dehydrogenase: a bifunctional enzyme with broad substrate specificity and 6-phosphogluconolactonase activity. Archives of Biochemistry and Biophysics 415 229-234.
13. Collard F, Collet JF, Gerin I, Veiga-da-Cunha M & van Schaftingen E 1999 Identification of the cDNA encoding human 6-phospho-gluconolactonase, the enzyme catalyzing the second step of the pentose phosphate pathway. FEBS Letters 459 223-226.
14. Czegle I, Piccirella S, Senesi S, Csala M, Mandl J, Bánhegyi G, Fulceri R & Benedetti A 2005 Cooperativity between 1β-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase is based on a common pyridine nucleotide pool in the lumen of the endoplasmic reticulum. Molecular and Cellular Endocrinology 248 24-25.
15. Draper N & Stewart PM 2005 11β-Hydroxysteroid dehydrogenase and the pre-receptor regulation of corticosteroid hormone action. Journal of Endocrinology 186 251-271.
16. Draper N, Walker EA, Bujalska IJ, Tomlinson JW, Chalder SM, Arlt W, Lavery GG, Bedendo O, Ray DW, Laing I et al. 2003 Mutations in the genes encoding 11β-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase interact to cause cortisone reductase deficiency. Nature Genetics 34 434-439.
17. Frost SC & Lane MD 1985 Evidence for the involvement of vicinal sulfhydryl groups in insulin-activated hexose transport by 3T3-L1 adipocytes. Journal of Biological Chemistry 260 2646-2652.
18. Gallo R, Gambelli F, Gava B, Sasdelli F, Tellone V, Masini M, Marchetti P, Dotta F & Sorrentino V 2007 Generation and expansion of multipotent mesenchymal progenitor cells from cultured human pancreatic islets. Cell Death and Differentiation 14 1860-1871.
19. Gomez-Sanchez EP, Romero DG, de Rodriguez AF, Warden MP, Krozowski Z & Gomez-Sanchez CE 2007 Hexose-6-phosphate dehydrogenase and 11β-hydroxysteroid dehydrogenase-1 tissue distribution in the rat. Endocrinology 149 525-533.
20. Hewitt KN, Walker EA & Stewart PM 2004 Hexose-6-phosphate dehydrogenase and redox control of 11β-hydroxysteroid dehydrogenase type 1 activity. Endocrinology 146 2539-2543.
21. Kim J, Temple KA, Jones SA, Meredith KN, Basko JL & Brady MJ 2007 Differential modulation of 3T3-L1 adipogenesis mediated by 11β-hydroxysteroid dehydrogenase-1 levels. Journal of Biological Chemistry 282 11038-11046.
22. Lavery GG, Walker EA, Draper N, Jeyasuria P, Marcos J, Shackleton CH, Parker KL, White PC & Stewart PM 2006 Hexose-6-phosphate dehydrogenase knock-out mice lack 11β-hydroxysteroid dehydrogenase type 1-mediated glucocorticoid generation. Journal of Biological Chemistry 281 6546-6551.
23. Lavery GG, Walker EA, Turan N, Rogoff D, Ryder JW, Shelton JM, Richardson JA, Falciani F, White PC, Stewart PM et al. 2008 Deletion of hexose-6-phosphate dehydrogenase activates the unfolded protein response pathway and induces skeletal myopathy. Journal of Biological Chemistry 283 8453-8461.
24. Leuzzi R, Bánhegyi G, Kardon T, Marcolongo P, Capecchi PL, Burger HJ, Benedetti A & Fulceri R 2003 Inhibition of microsomal glucose-6-phosphate transport in human neutrophils results in apoptosis: a potential explanation for neutrophil dysfunction in glycogen storage disease type 1b. Blood 101 2381-2387.
25. Marcolongo P, Piccirella S, Senesi S, Wunderlich L, Gerin I, Mandl J, Fulceri R, Bánhegyi G & Benedetti A 2007 The glucose-6-phosphate transporter - hexose-6-phosphate dehydrogenase - 11β-hydroxysteroid dehydrogenase type 1 system of the adipose tissue. Endocrinology 148 2487-2495.
26. Margittai E & Bánhegyi G 2008 Isocitrate dehydrogenase: a NADPH-generating enzyme in the lumen of the endoplasmic reticulum. Archives of Biochemistry and Biophysics 471 184-190.
27. Mason PJ, Stevens D, Diez A, Knight SW, Scopes DA & Vulliamy TJ 1999 Human hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) encoded at 1p36: coding sequence and expression. Blood Cells, Molecules and Diseases 25 30-37.
28. Napolitano A, Voice MW, Edwards CR, Seckl JR & Chapman KE 1998 11β-Hydroxysteroid dehydrogenase 1 in adipocytes: expression is differentiation-dependent and hormonally regulated. Journal of Steroid Biochemistry and Molecular Biology 64 251-260.
29. Nashev LG, Chandsawangbhuwana C, Balazs Z, Atanasov AG, Dick B, Frey FJ, Baker ME & Odermatt A 2007 Hexose-6-phosphate dehydrogenase modulates 11β-hydroxysteroid dehydrogenase type 1-dependent metabolism of 7-keto- and 7β-hydroxy-neurosteroids. PLoS ONE 2 e561.
30. Odermatt A, Arnold P, Stauffer A, Frey BM & Frey FJ 1999 The N-terminal anchor sequences of 11β-hydroxysteroid dehydrogenases determine their orientation in the endoplasmic reticulum membrane. Journal of Biological Chemistry 274 28762-28770.
31. Odermatt A, Atanasov AG, Balazs Z, Schweizer RAS, Nashev LG, Schuster D & Langer T 2006 Why is 11β-hydroxysteroid dehydrogenase type 1 facing the endoplasmic reticulum lumen? Physiological relevance of the membrane topology of 11β-HSD1 Molecular and Cellular Endocrinology 248 15-23.
32. Ozols J 1993 Isolation and the complete amino acid sequence of lumenal endoplasmic reticulum glucose-6-phosphate dehydrogenase. PNAS 90 5302-5306.
33. Pfaffl MW 2001 A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Research 29 2002-2007.
34. Piccirella S, Czegle I, Lizak B, Margittai E, Senesi S, Papp E, Csala M, Fulceri R, Csermely P, Mandl J et al. 2006 Uncoupled redox systems in the lumen of the endoplasmic reticulum. Pyridine nucleotides stay reduced in an oxidative environment. Journal of Biological Chemistry 281 4671-4677.
35. Seckl JR & Walker BR 2004 11β-Hydroxysteroid dehydrogenase type 1 as a modulator of glucocorticoid action: from metabolism to memory. Trends in Endocrinology and Metabolism 15 418-424.
36. Seckl JR, Morton NM, Chapman KE & Walker BR 2004 Glucocorticoids and 11β-hydroxysteroid dehydrogenase in adipose tissue. Recent Progress in Hormone Research 59 359-393.
37. De Sousa Peixoto RA, Turban S, Battle JH, Chapman KE, Seckl JR & Morton NM 2008 Preadipocyte 11β-hydroxysteroid dehydrogenase type 1 is a keto-reductase and contributes to diet-induced visceral obesity in vivo. Endocrinology 149 1861-1868.
38. Takahashi T & Hori SH 1978 Intramembraneous localization of rat liver microsomal hexose-6-phosphate dehydrogenase and membrane permeability to its substrates. Biochimica et Biophysica Acta 524 262-276.
39. Tomlinson JW & Stewart PM 2002 The functional consequences of 11β-hydroxysteroid dehydrogenase expression in adipose tissue. Hormone and Metabolic Research 34 746-751.
40. Tomlinson JW & Stewart PM 2005 Mechanisms of disease: selective inhibition of 11β-hydroxysteroid dehydrogenase type 1 as a novel treatment for the metabolic syndrome. Nature Clinical Practice. Endocrinology and Metabolism 1 92-99.
41. Tomlinson JW, Walker EA, Bujalska IJ, Draper N, Lavery GG, Cooper MS, Hewison M & Stewart PM 2004 11β-Hydroxysteroid dehydrogenase type 1: a tissue specific regulator of glucocorticoid response. Endocrine Reviews 25 831-866.
42. Varma MJ, Breuls RG, Schouten TE, Jurgens WJ, Bontkes HJ, Schuurhuis GJ, van Ham SM & van Milligen FJ 2007 Phenotypical and functional characterization of freshly isolated adipose tissue-derived stem cells. Stem Cells and Development 16 91-104.
43. Zuk PA, Zhu M, Mizuno H, Huang J, Futrell JW, Katz AJ, Benhaim P, Lorenz HP & Hedrick MH 2001 Multilineage cells from human adipose tissue: implications for cell-based therapies. Tissue Engineering 7 211-218.
44. Zuk PA, Zhu M, Ashjian P, DeUgarte DA, Huang JI, Mizuno H, Alfonso ZC, Fraser JK, Benhaim P & Hedrick MH 2002 Human adipose tissue is a source of multipotent stem cells. Molecular Biology of the Cell 13 4279-4295.