Design and synthesis of novel 2′,3′-dideoxy-4′-selenonucleosides as potential antiviral agents

Bioorganic and Medicinal Chemistry

Volumn 16, Issue 23, 2008, Pages 9891-9897

  Jeong, Lak Shin ^a   Choi, Yoo Na ^a   Tosh, Dilip K ^a   Choi, Won Jun ^a   Kim, Hea Ok ^a   Choi, Jungwon ^b  

^a Ewha Womans University   (South Korea)

^b Suwon University   (South Korea)

Author keywords

2 ,3 Dideoxy 4 selenonucleosides; 2 ,3 Dideoxycytidine; Anti HIV agents; Pummerer type condensation; South conformation

Indexed keywords

1,4 DI O METHANESULFONYL 5 TERT BUTYLDIPHENYLSILANYLOXYPENTANE; 2 (TERT BUTYLDIPHENYLSILYLOXYMETHYL) DIHYDROSELENOFURAN; 2 (TERT BUTYLDIPHENYLSILYLOXYMETHYL) DIHYDROSELENOFURAN 1 OXIDE; 2',3' DIDEOXYNUCLEOSIDE DERIVATIVE; 5 (TERT BUTYLDIPHENYLSILANYLOXY)PENTANE 1,4 DIOL; ALPHA DEXTRO 2',3' DIDEOXY 4' SELENOCYTIDINE; ALPHA DEXTRO 2',3' DIDEOXY 4' SELENOTHYMIDINE; ALPHA DEXTRO 2',3' DIDEOXY 4' SELENOURIDINE; ALPHA DEXTRO 5' BENZOYL 2',3' DIDEOXY 4' SELENO N 3 BENZOYLCYTIDINE; ALPHA,BETA DEXTRO 2',3' DIDEOXY 4' SELENOTHYMIDINE; ALPHA,BETA DEXTRO 5' TERT BUTYLDIPHENYLSILYL 2',3' DIDEOXY 4' SELENOTHYMIDINE; ALPHA,BETA DEXTRO 5' TERT BUTYLDIPHENYLSILYL 2',3' DIDEOXY 4' SELENOURIDINE; ANTIVIRUS AGENT; BETA DEXTRO 2',3' DIDEOXY 4' SELENOCYTIDINE; BETA DEXTRO 2',3' DIDEOXY 4' SELENOTHYMIDINE; BETA DEXTRO 2',3' DIDEOXY 4' SELENOURIDINE; BETA DEXTRO 5' BENZOYL 2',3' DIDEOXY 4' SELENO N 3 BENZOYLCYTIDINE; BETA DEXTRO 5' TERT BUTYLDIPHENYLSILYL 2',3' DIDEOXY 4' SELENO N 4 BENZOYLCYTIDINE; DEXTRO GLUTAMIC ACID; RNA DIRECTED DNA POLYMERASE; UNCLASSIFIED DRUG;

ARTICLE; DRUG CONFORMATION; DRUG DESIGN; DRUG SYNTHESIS; POLYMERIZATION; RING CLOSING METATHESIS; STEREOCHEMISTRY; X RAY CRYSTALLOGRAPHY;

ANTIVIRAL AGENTS; CRYSTALLOGRAPHY, X-RAY; DIDEOXYNUCLEOSIDES; DRUG DESIGN; HIV; MODELS, CHEMICAL; MOLECULAR STRUCTURE; SELENIUM;

EID: 55749104380     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2008.10.034     Document Type: Article

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