Direct drug loading into preformed porous solid dosage units by the controlled particle deposition (CPD), a new concept for improved dissolution using SCF-technology

Journal of Pharmaceutical Sciences

Volumn 97, Issue 10, 2008, Pages 4416-4424

  Wischumerski, Ragna S ^a   Türk, Michael ^b   Wahl, Martin A ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b UNIVERSITY OF KARLSRUHE   (Germany)

Author keywords

Controlled particle deposition (cpd); Dissolution rate; Ibuprofen; Particle size; Precipitation; Solid dosage form; Supercritical fluids

Indexed keywords

CARBON DIOXIDE; DRUG CARRIER; HYDROXYETHYLCELLULOSE; IBUPROFEN; MICROCRYSTALLINE CELLULOSE;

ARTICLE; CALCULATION; CONTROLLED PARTICLE DEPOSITION; DRUG DOSAGE FORM; DRUG SOLUBILITY; PARTICLE SIZE; PHARMACEUTICAL ENGINEERING; POROSITY; PRECIPITATION; PREDICTION; SUPERCRITICAL FLUID; TABLET FORMULATION;

EID: 55749104235     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.21323     Document Type: Article

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