Triiodothyronine utilizes phosphatidylinositol 3-kinase pathway to activate anti-apoptotic myeloid cell leukemia-1

Journal of Molecular Endocrinology

Volumn 41, Issue 3-4, 2008, Pages 177-186

  Pietrzak, Maciej ^a   Puzianowska Kuznicka, Monika ^a,b  

^a MOSSAKOWSKI MEDICAL RESEARCH CENTRE   (Poland)

^b MEDICAL CENTER FOR POSTGRADUATE EDUCATION   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS INHIBITOR; CELL NUCLEUS RECEPTOR; CYCLIC AMP; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; DEATH RECEPTOR 4; LIOTHYRONINE; MYELOID CELL LEUKEMIA 1 PROTEIN; NUCLEAR RECEPTOR TR; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BCL 2; THYROID HORMONE RECEPTOR BETA; UNCLASSIFIED DRUG; WORTMANNIN;

APOPTOSIS; ARTICLE; CELL STRAIN HEK293; CONTROLLED STUDY; ENZYME ACTIVITY; GENE ACTIVATION; GENE EXPRESSION; GENE SEQUENCE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMOTER REGION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; APOPTOSIS; CELL LINE; GENE EXPRESSION REGULATION; HUMANS; PROTEIN BINDING; PROTEIN ISOFORMS; PROTO-ONCOGENE PROTEINS C-BCL-2; RECEPTORS, THYROID HORMONE; RESPONSE ELEMENTS; RETINOID X RECEPTORS; SEQUENCE DELETION; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC; TRIIODOTHYRONINE;

EID: 55749099782     PISSN: 09525041     EISSN: None     Source Type: Journal    
DOI: 10.1677/JME-08-0010     Document Type: Article

References (45)

1. Cao X, Kambe F, Moeller LC, Refetoff S & Seo H 2005 Thyroid hormone induces rapid activation of Akt/protein kinase B-mammalian target of rapamycin-p70S6K cascade through phosphatidylinositol 3-kinase in human fibroblasts. Molecular Endocrinology 19 102-112.
2. Casas F, Rochard P, Rodier A, Cassar-Malek I, Marchal-Victorion S, Wiesner RJ, Cabello G & Wrutniak C 1999 A variant form of the nuclear triiodothyronine receptor c-ErbAα1 plays a direct role in regulation of mirochondrial RNA synthesis. Molecular and Cellular Biology 19 7913-7924.
3. Chen JD & Evans RM 1995 A transcriptional co-repressor that interacts with nuclear hormone receptors. Nature 377 454-457.
4. Cheng SY 2000 Multiple mechanisms for regulation of the transcriptional activity of thyroid hormone receptors. In Reviews in Endocrine and Metabolic Disorders, pp 9-18. Ed D LeRoith. New York: Kluwer Academic.
5. Clohessy JG, Zhuang J, de Boer J, Gil-Gomez G & Brady HJ 2006 Mcl-1 interacts with truncated Bid and inhibits its induction of cytochrome c release and its role in receptor-mediated apoptosis. Journal of Biological Chemistry 281 5750-5759.
6. van Delft MF & Huang DC 2006 How the Bcl-2 family of proteins interact to regulate apoptosis. Cell Research 16 203-213.
7. Drabkin H, Kao FT, Hartz J, Hart I, Gazdar A, Weinberger C, Evans R & Gerber M 1988 Localization of human ERBA2 to the 3p22-3p24.1 region of chromosome 3 and variable deletion in small cell lung cancer. PNAS 85 9258-9262.
8. Eckey M, Moehren U & Baniahmad A 2003 Gene silencing by the thyroid hormone receptor. Molecular and Cellular Endocrinology 213 13-22.
9. Fraser D, Wakefield L & Phillips A 2002 Independent regulation of transforming growth factor-β1 transcription and translation by glucose and platelet-derived growth factor. American Journal of Pathology 161 1039-1049.
10. 3 treatment increases mitosis, then bax expression and apoptosis in the optic lobe of the chick embryo. Neuroscience Letters 231 127-130.
11. Gosden JR, Middleton PG, Rout D & Angelis C 1986 Chromosomal localization of the human oncogene ERBA2. Cytogenetics and Cell Genetics 43 150-153.
12. Han J, Goldstein LA, Gastman BR & Rabinowich H 2006 Interrelated roles for Mcl-1 and BIM in regulation of TRAIL-mediated mitochondrial apoptosis. Journal of Biological Chemistry 281 10153-10163.
13. Harvey CR & Williams GR 2002 Mechanism of thyroid hormone action. Thyroid 12 441-446.
14. Jee SH, Chin HC, Tsai TF, Tsai WL, Liao YH, Chu CY & Kuo ML 2002 The phosphotidyl inositol 3-kinase/Akt signal pathway is involved in interleukin-6-mediated Mcl-1 upregulation and anti-apoptosis activity in basal cell carcinoma cells. Journal of Investigative Dermatology 119 1121-1127.
15. Kenessey A & Ojamaa K 2006 Thyroid hormone stimulates protein synthesis in the cardiomyocyte by activating the Akt-mTOR and p70S6K pathways. Journal of Biological Chemistry 281 20666-20672.
16. Kuo ML, Chuang SE, Lin MT & Yang SY 2001 The involvement of PI3-K/ Akt-dependent up-regulation of Mcl-1 in the prevention of apoptosis of Hep3B cells by interleukin-6. Oncogene 20 677-685.
17. Kuzman JA, Gerdes AM, Kobayashi S & Liang Q 2005 Thyroid hormone activates Akt and prevents serum starvation-induced cell death in neonatal rat cardiornyocytes. Journal of Molecular and Cellular Cardiology 39 841-844.
18. Lei J, Mariash CN & Ingbar DH 2004 3,3′,5-Triiodo-L-thyronine up-regulation of Na,K-ATPase activity and cell surface expression in alveolar epithelial cells is Src kinase- and phosphoinositide 3-kinase-dependent. Journal of Biological Chemistry 279 47589-47600.
19. Leu JI, Dumont P, Hafey M, Murphy ME & George DL 2004 Mitochondrial p53 activates Bak and causes disruption of a Bak-Mel1 complex. Nature Cell Biology 6 443-450.
20. McKenna NJ, Lanz RB & O'Malley BW 1999 Nuclear receptor coregulators: cellular and molecular biology. Endocrine Reviews 20 321-344.
21. Michels J, Johnson PW & Packham G 2005 Mcl-1. International Journal of Biochemistry and Cell Biology 37 267-271.
22. Moeller LC, Dumitrescu AM & Refetoff S 2005 Cytosolic action of thyroid hormone leads to induction of hypoxia-inducible factor-1α and glycolytic genes. Molecular Endocrinology 19 2955-2963
23. Moeller LC, Cac, X, Dumitrescu AM, Seo H & Refetoff S 2006 Thyroid hormone mediated changes in gene expression can be initiated by cytosolic action of the thyroid hormone receptor β through the phosphatidylinositol 3-kinase pathway. Nuclear Receptor Signaling 4 e020.
24. Nijhawan D, Fang M, Traer E, Zhong Q Gao W, Du F & Wang X 2003 Elimination of Mcl-1 is required for the initiation of apoptosis following ultraviolet irradiation. Genes and Development 17 1475-1486.
25. Oetting A & Yen PM 2007 New insights into thyroid hormonc action. Best Practice and Research. Clinical Endocrinology and Metabolism 21 193-208.
26. Onate SA, Tsai SY Tsai MJ & O'Malley BW 1995 Sequence and characterization of coactivator for the steroid hormone receptor superfamily. Science 270 1354-1357.
27. Puzianowska-Kuznicka M, Pietrzak M, Turowska O & Nauman A 2006 Thyroid hormones and their receptors in the regulation of cell proliferation. Acta Biochimica Polonica 53 641-650.
28. Rastinjead F 2001 Retinoid X receptor and its partners in the nuclear receptor family. Current Opinion in Structural Biology 11 33-38.
29. Sachs LM, Abdallah B, Hassan A, Levi G, De Luze A, Reed JC & Demeneix BA 1997 Apoptosis in Xenapus tadpole tail muscles involves Bax-dependent pathways. FASEB Journal 11 801-808.
30. Storey NM, Gentile S, Ullah H, Russo A, Muessel M, Erxleben C & Armstrong DL 2006 Rapid signaling at the plasma membrane by a nuclear receptor for thyroid hormone. PNAS 103 5197-5201.
31. Szanto A, Narkar V, Shen Q, Uray IP, Davies PJ & Nagy L 2004 Retinoid X receptors: X-ploying their (patho) physiological functions. Cell Death and Differentiation 11 S126-S143.
32. Tata JR 2007 A hormone for all seasons. Perspectives in Biology and Medicine 50 89-103.
33. Townsend KJ, Zhou P, Qian L, Bieszczad CK, Lowrey CH, Yen A & Craig RW 1999 Regulation of MCL1 through a serum response factor/Elk-1-mediated mechanism links expression of a viability-promoting member of the BCL2 family to the induction of hematopoietic cell differentiation. Journal of Biological Chemistry 274 1801-1813.
34. Turowska O, Nauman A, Pietrzak M, Poplawski P, Master A, Nygard M, Bondesson M, Tanski Z & Puzianowska-Kuznicka M 2007 Over-expression of E2171 in clear cell renal cell carcinoma: a potential impact of erroneous regulation by thyroid hormone nuclear receptors. Thyroid 17 1039-1048.
35. Upadhyay G, Singh R, Kumar A, Kumar S, Kapoor A & Godbole MM 2004 Severe hyperthyroidism induces mitochondria-mediated apoptosis in rat liver. Hepatology 39 1120-1130.
36. 3) is a survival factor for pancreatic β-cells undergoing apoptosis. Journal of Cellular Physiology 206 309-321.
37. 3 in pancreatic β cells. Journal of Molecular Endocrinology 38 221-233.
38. Wang JM, Chao JR, Chen W, Kuo ML, Yen JJ & Yang-Yen HF 1999 The antiapoptotic gene mcl-1 is up-regulated by the phosphatidylinositol 3-kinase/Akt signaling pathway through a transcription factor complex containing CREB. Molecular and Cellular Biology 19 6195-6206.
39. Wang JM, Lai MZ & Yang-Yen HF 2003 Interleukin-3 stimulation of mcl-1 gene transcription involves activation of the PU.1 transcription factor through a p38 mitogen-activated protein kinase-dependent pathway. Molecular and Cellular Biology 23 1896-1909.
40. Weiss RE & Ramos HE 2004 Thyroid hormone receptor subtypes and their interaction with steroid receptor coactivators. Vitamins and Hormones 68 185-207.
41. Willis SN, Chen L, Dewson G, Wei A, Naik E, Fletcherfl, Adams JM & Huang DC 2005 Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins. Genes and Development 19 1294-1305.
42. Yang T, Kozopas KM & Craig RW 1995 The intracellular distribution and pattern of expression of Mcl-1 overlap with, but are not identical to, those of Bcl-2. Journal of Cell Biology 128 1173-1184.
43. Yang-Yen HE 2006 Mcl-1: a highly regulated cell death and survival controller. Journal of Biomedical Science 13 201-204.
44. Yehuda-Shnaidman E, Kalderon B & Bar-Tana J 2005 Modulation of mitochondrial transition pore components by thyroid hormone. Endocrinology 146 2462-2472.
45. Yen PM, Ando S, Feng X, Liu Y, Maruvada P & Xia X 2006 Thyroid hormone action at the cellular, genomic and target gene levels. Molecular and Cellular Endocrinology 246 121-127.