Severe psychomotor and metabolic damages caused by a mutant thyroid hormone receptor alpha 1 in mice: Can patients with a similar mutation be found and treated?

Acta Paediatrica, International Journal of Paediatrics

Volumn 97, Issue 12, 2008, Pages 1605-1610

  Vennström, Björn ^a   Mittag, Jens ^a   Wallis, Karin ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Brain; Hypothyroidism; Metabolism; Resistance to thyroid hormone; Thyroid hormone receptor

Indexed keywords

LIOTHYRONINE; MUTANT PROTEIN; THYROID HORMONE RECEPTOR ALPHA; THYROID HORMONE RECEPTOR BETA;

CLINICAL FEATURE; DISEASE MODEL; DRUG MEGADOSE; GENE MUTATION; HORMONE SUBSTITUTION; HUMAN; HYPOTHYROIDISM; METABOLIC DISORDER; MOUSE; NONHUMAN; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; PSYCHOMOTOR DISORDER; REVIEW; THYROID HORMONE RESISTANCE;

ANIMALS; CONGENITAL HYPOTHYROIDISM; DISEASE MODELS, ANIMAL; HOMEOSTASIS; HUMANS; MICE; MICE, TRANSGENIC; MUTATION; PHENOTYPE; PSYCHOMOTOR DISORDERS; THYROID HORMONE RECEPTORS ALPHA; THYROID HORMONE RESISTANCE SYNDROME; THYROID HORMONES;

EID: 55649089643     PISSN: 08035253     EISSN: 16512227     Source Type: Journal    
DOI: 10.1111/j.1651-2227.2008.01031.x     Document Type: Review

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