Nicorandil, a potassium channel opener and nitric oxide donor, improves the frequent urination without changing the blood pressure in rats with partial bladder outlet obstruction

Biological and Pharmaceutical Bulletin

Volumn 31, Issue 11, 2008, Pages 2079-2082

  Sudo, Hirokazu ^a   Yogo, Kenji ^a   Ishizuka, Nobuhiko ^a   Otsuka, Hideaki ^b   Horie, Shigeo ^c   Saito, Keiji ^a  

^a CHUGAI PHARMACEUTICAL CO LTD   (Japan)

^b HIROSHIMA UNIVERSITY   (Japan)

^c TEIKYO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Benign prostatic hyperplasia; KATP channel; Nicorandil; Nitric oxide; Overactive bladder

Indexed keywords

CROMAKALIM; ISOSORBIDE DINITRATE; NICORANDIL; NITRIC OXIDE DONOR; POTASSIUM CHANNEL STIMULATING AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLADDER NECK STENOSIS; BLOOD PRESSURE; CONTROLLED STUDY; DOSE RESPONSE; DRUG SELECTIVITY; FEMALE; HEART RATE; MICTURITION; NONHUMAN; RAT; URINARY FREQUENCY;

ANIMALS; BLOOD PRESSURE; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HEART RATE; ION CHANNEL GATING; NICORANDIL; NITRIC OXIDE DONORS; POTASSIUM CHANNELS; RATS; RATS, SPRAGUE-DAWLEY; URINARY BLADDER NECK OBSTRUCTION; URINATION DISORDERS;

EID: 55549143026     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.31.2079     Document Type: Article

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