The putrescine analogue 1,4-diamino-2-butanone affects polyamine synthesis, transport, ultrastructure and intracellular survival in Leishmania amazonensis

Microbiology

Volumn 154, Issue 10, 2008, Pages 3104-3111

  Vannier Santos, Marcos A ^a   Menezes, Diego ^a   Oliveira, Marcus F ^b   de Mello, Fernando G ^b  

^a INSTITUTO OSWALDO CRUZ   (Brazil)

^b FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIAMINO 2 BUTANONE; 3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ORNITHINE DECARBOXYLASE; POLYAMINE; PUTRESCINE DERIVATIVE; UNCLASSIFIED DRUG; 1,4-DIAMINOBUTANONE; ANTIPROTOZOAL AGENT; DRUG DERIVATIVE; PUTRESCINE; TETRAZOLIUM; THIAZOLE DERIVATIVE; THIAZOLYL BLUE;

ARTICLE; BACTERIAL GROWTH; CELL PROLIFERATION; CELL SURVIVAL; CELL ULTRASTRUCTURE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME ACTIVITY; IN VITRO STUDY; LEISHMANIA; LIPID PEROXIDATION; NONHUMAN; POLYAMINE SYNTHESIS; PRIORITY JOURNAL; PROTEIN TRANSPORT; SPECIES DIFFERENTIATION; TRANSMISSION ELECTRON MICROSCOPY; TRICHOMONAS FOETUS; TRYPANOSOMA CRUZI; ANIMAL; CELL CULTURE; DRUG EFFECT; GROWTH, DEVELOPMENT AND AGING; MACROPHAGE; METABOLISM; MITOCHONDRION; MOUSE; PARASITOLOGY; ULTRASTRUCTURE;

LEISHMANIA AMAZONENSIS; MURINAE; PROTOZOA; TRITRICHOMONAS FOETUS; TRYPANOSOMA CRUZI;

ANIMALS; ANTIPROTOZOAL AGENTS; CELL PROLIFERATION; CELLS, CULTURED; LEISHMANIA; LIPID PEROXIDATION; MACROPHAGES; MICE; MICROSCOPY, ELECTRON, TRANSMISSION; MITOCHONDRIA; ORNITHINE DECARBOXYLASE; POLYAMINES; PUTRESCINE; TETRAZOLIUM SALTS; THIAZOLES;

EID: 55549139794     PISSN: 13500872     EISSN: None     Source Type: Journal    
DOI: 10.1099/mic.0.2007/013896-0     Document Type: Article

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