Expression of CD11b/CD18 adhesion molecules on circulating phagocytes - A novel aid to diagnose infection in patients with cancer

Supportive Care in Cancer

Volumn 16, Issue 12, 2008, Pages 1389-1396

  Kallio, R ^a   Aalto, H ^b   Takala, A ^b   Ohtonen, P ^a   Collan, J ^c   Siitonen, S ^c   Joensuu, H ^c   Syrjala, H ^a   Repo, H ^c  

^a OULU UNIVERSITY HOSPITAL   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

^c HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

Author keywords

Advanced cancer; Infection; Neutrophils; Solid tumors

Indexed keywords

C REACTIVE PROTEIN; CD11B ANTIGEN; CD18 ANTIGEN; CELL ADHESION MOLECULE;

ADULT; ADVANCED CANCER; AGED; ANTIGEN EXPRESSION; ARTICLE; CONTROLLED STUDY; DIAGNOSTIC VALUE; DIFFERENTIAL DIAGNOSIS; FEMALE; FEVER; HUMAN; HUMAN CELL; INFECTION; MAJOR CLINICAL STUDY; MALE; MONOCYTE; NEUTROPHIL; PHAGOCYTE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SOLID TUMOR;

ADULT; AGED; ANTIGENS, CD11B; ANTIGENS, CD18; CASE-CONTROL STUDIES; CELL ADHESION; FEMALE; FLOW CYTOMETRY; HUMANS; INFECTION; MALE; MIDDLE AGED; MONOCYTES; NEOPLASMS; NEUTROPHILS; PREDICTIVE VALUE OF TESTS; ROC CURVE; UP-REGULATION;

EID: 55549107506     PISSN: 09414355     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00520-008-0440-2     Document Type: Article

References (33)

1. H Aalto A Takala H Kautiainen H Repo 2005 Peripheral blood phagocyte CD14 and CD 11b expression on admission to hospital in relation to mortality among patients with community-acquired infection Inflamm Res 54 428 434
2. AM Bal IM Gould 2007 Empirical antimicrobial treatment for chemotherapy-induced febrile neutropenia Int J Antimicrob Agents 29 501 509
3. R Bone RA Balk FB Cerra RP Dellinger AM Fein WA Knaus RM Schein WJ Sibbal 1992 Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine Chest 101 1644 1655
4. K Brandl T Gluck C Huber B Salzberger W Falk P Hartmann 2005 TLR-4 surface display on human monocytes is increased in septic patients Eur J Med Res 10 319 324
5. J Calafat TW Kuijpers H Janssen N Borregaard AJ Verhoeven D Roos 1993 Evidence for small intracellular vesicles in human blood phagocytes containing cytochrome b558 and the adhesion molecule CD11b/CD18 Blood 81 3122 3129
6. R Dziarski D Gupta 2005 Staphylococcus aureus peptidoglygan is a toll-like receptor 2 activator: a reevaluation Infec Immun 73 5212 5216
7. HA Edens CA Parkos 2003 Neutrophil transendothelial migration and alteration in vascular permeability: focus on neutrophil-derived azurocidin Curr Opin Hematol 10 25 30
8. T Ek M Pinkava J Abrahamsson 2005 Ara-C fever and infections after high-dose ara-C treatment in pediatric lymphoid malignancies J Pediatr Hematol Oncol 27 364 369
9. DT Fearon LA Collins 1983 Increased expression of C3b receptors on polymorphonuclear leukocytes induced by chemotactic factors and by purification procedures J Immunol 130 370 375
10. A Freifeld J Sankaranarayanan F Ullrich J Sun 2008 Clinical practice patterns of managing low-risk adult febrile neutropenia during cancer chemotherapy in the USA Supprot Care Cancer 16 181 191
11. R Kallio A Bloigu HM Surcel H Syrjala 2001 C-reactive protein and erythrocyte sedimentation rate in differential diagnosis between infections and neoplastic fever in patients with solid tumours and lymphomas Support Care Cancer 9 124 128
12. R Kallio HM Surcel A Bloigu H Syrjala 2000 C-reactive protein, procalcitonin and interleukin-8 in the primary diagnosis of infections in cancer patients Eur J Cancer 36 889 894
13. R Kallio HM Surcel A Bloigu H Syrjala 2001 Admission neopterin and interleukin 12 concentrations in identifying infections in adult cancer patients Cytokine 13 371 374
14. R Kallio HM Surcel A Bloigu H Syrjala 2001 Balance between interleukin-10 and interleukin-12 in adult cancer patients with or without infection Eur J Cancer 37 857 861
15. ML Kylanpaa-Back A Takala E Kemppainen P Puolakkainen H Kautiainen SE Jansson R Haapiainen H Repo 2001 Cellular markers of systemic inflammation and immune suppression in patients with organ failure due to severe acute pancreatitis Scand J Gastroenterol 36 1100 1107
16. RY Lin ME Astiz JC Saxon EC Rackow 1993 Altered leukocyte immunophenotypes in septic shock. Studies of HLA-DR, CD11b, CD14, and IL-2R expression Chest 104 847 853
17. I Nupponen S Andersson AL Jarvenpaa H Kautiainen H Repo 2001 Neutrophil CD11b expression and circulating interleukin-8 as diagnostic markers for early-onset neonatal sepsis Pediatrics 108 E12
18. N Penel C Fournier S Clisant M N'Guyen 2004 Causes of fever and value of C-reactive protein and procalcitonin in differentiating infections from paraneoplastic fever Support Care Cancer 12 593 598
19. EJ Pesonen K Hockerstedt H Makisalo J Vuorte SE Jansson A Orpana SL Karonen H Repo 2000 Transhepatic neutrophil and monocyte activation during clinical liver transplantation Transplantation 69 1458 1464
20. PY Perera TN Mayadas O Takeuchi S Akina H Zaks-Ziberman SM Goyert SN Voge 2001 CD11b/CD18 acts in concert with CD 14 and Toll-like receptor (TLR) 4 to elicit full lipopolysaccharide and taxol-inducible gene expression J Immunol 166 574 581
21. H Repo SE Jansson M Leirisalo-Repo 1993 Flow cytometric determination of CD11b upregulation in vivo J Immunol Methods 164 193 202
22. H Repo SE Jansson M Leirisalo-Repo 1995 Anticoagulant selection influences flow cytometric determination of CD11b upregulation in vivo and ex vivo J Immunol Methods 185 65 79
23. H Repo YP Rochon BR Schwartz SR Sharar RK Winn JM Harlan 1997 Binding of human peripheral blood polymorphonuclear leukocytes to E-selectin (CD62E) does not promote their activation J Immunol 159 943 951
24. CS Rinder JL Bonan HM Rinder J Mathew R Hines BR Smith 1992 Cardiopulmonary bypass induces leukocyte-platelet adhesion Blood 79 1201 1205
25. H Sengelov L Kjeldsen MS Diamond TA Springer N Borregaard 1993 Subcellular localization and dynamics of Mac-1 (alpha m beta 2) in human neutrophils J Clin Invest 92 1467 1476
26. Sobin LH, Wittekind Ch (2002) TNM Classification of malignant tumours, 6th edn. Wiley-Liss, New York
27. A Takala I Jousela O Takkunen H Kautiainen SE Jansson A Orpana SL Karonen H Repo 2002 A prospective study of inflammation markers in patients at risk of indirect acute lung injury Shock 17 252 257
28. R Turunen S Andersson I Nupponen H Kautiainen S Siitonen H Repo 2005 Increased CD11b-density on circulating phagocytes as an early sign of late-onset sepsis in extremely low-birth-weight infants Pediatr Res 57 270 275
29. NB Vedder JM Harlan 1988 Increased surface expression of CD11b/CD18 (Mac-1) is not required for stimulated neutrophil adherence to cultured endothelium J Clin Invest 81 676 682
30. E Velasco R Byington CAS Martins M Schirmer LMC Dias VMSC Goncalves 2006 Comparative study of clinical characteristics of neutropenic and non-neutropenic adult cancer patients with bloodstream infections Eur J Clin Microbiol Infect Dis 25 1 7
31. H Wisplinghoff H Seifert RP Wenzel MB Edmond 2003 Current trends in the epidemiology of nosocomial bloodstream infections in patients with hematological malignancies and solid neoplasms in hospitals in the United States Clin Infet Dis 36 1103 1010
32. JA Zell JC Chang 2005 Neoplastic fever: a neglected paraneoplastic syndrome Support Care Cancer 13 870 877
33. X Zhou XP Gao J Fan Q Liu KN Anwar RS Frey AB Malik 2005 LPS activation of Toll-like receptor 4 signals CD11b/CD18 expression in neutrophils Am J Physiol Lung Cell Mol Physiol 288 L655 L662