Comparative study of clinical characteristics of neutropenic and non-neutropenic adult cancer patients with bloodstream infections

European Journal of Clinical Microbiology and Infectious Diseases

Volumn 25, Issue 1, 2006, Pages 1-7

  Velasco, E ^a   Byington, R ^b   Martins, C A S ^b   Schirmer, M ^b   Dias, L M C ^b   Goncalves V M S C ^b  

^a Instituto Nacional de Câncer ^*  (Brazil)

^b INSTITUTO NACIONAL DE CÂNCER   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ACINETOBACTER; ACUTE LEUKEMIA; ADULT; AGED; ARTICLE; BACTERIAL INFECTION; BACTERIUM ISOLATION; BLOODSTREAM INFECTION; BONE MARROW TRANSPLANTATION; CANCER PATIENT; CANDIDIASIS; CENTRAL VENOUS CATHETER; CLINICAL FEATURE; COMORBIDITY; COMPARATIVE STUDY; CONTROLLED STUDY; ESCHERICHIA COLI; FEMALE; GENETIC HETEROGENEITY; GRAM NEGATIVE BACTERIUM; HEMATOLOGIC MALIGNANCY; HUMAN; HUMAN CELL; INDWELLING CATHETER; INFECTION; KLEBSIELLA PNEUMONIAE; LYMPHOMA; MAJOR CLINICAL STUDY; MALE; MORTALITY; NEUTROPENIA; NEUTROPHIL COUNT; PRIORITY JOURNAL; PROSPECTIVE STUDY; RISK FACTOR; SOLID TUMOR; STAPHYLOCOCCUS AUREUS;

ADULT; AGED; AGED, 80 AND OVER; BACTEREMIA; BLOOD-BORNE PATHOGENS; COMORBIDITY; FEMALE; FUNGEMIA; HEMATOLOGIC NEOPLASMS; HUMANS; INCIDENCE; MALE; MIDDLE AGED; NEOPLASMS; NEUTROPENIA; PROSPECTIVE STUDIES;

EID: 32144435404     PISSN: 09349723     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10096-005-0077-8     Document Type: Article

References (31)

1. Elting LS, Rubenstein EB, Rolston KVI, Bodey GP (1997) Outcomes of bacteremia in patients with cancer and neutropenia: observation from two decades of epidemiological and clinical trials. Clin Infect Dis 25:247-259
2. Wisplinghoff H, Comely AO, Moser S, Bethe U, Stützer H, Salzberger B, Fätkenheuer G, Seifert H (2003) Outcomes of nosocomial bloodstream infections in adult neutropenic patients: a prospective cohort and matched case-control study. Infect Control Hosp Epidemiol 24:905-911
3. Pittet D, Tarara D, Wenzel RP (1994) Nosocomial bloodstream infection in critically ill patients. JAMA 271:1598-1601
4. Spengler RF, Greenough WE III (1978) Hospital costs and mortality attributed to nosocomial bacteremias. JAMA 240:2455-2458
5. Wisplinghoff H, Seifer H, Wenzel RP, Edmond MB (2003) Current trends in the epidemiology of nosocomial bloodstream infections in patients with hematologic malignancies and solid neoplasms in hospitals in the United States. Clin Infect Dis 36:1103-1110
6. Jugo J, Kennedy R, Crowe MJ et al (2002) Trends in bacteraemia on the haematology and oncology units of a UK tertiary referral hospital. J Hosp Infect 50:48-55
7. Velasco E, Byington R, Martins CAS, Schirmer M, Dias LCM, Gonçalves VMSC (2003) Prospective evaluation of the epidemiology, microbiology, and outcome of bloodstream infections in hematologic patients in a single cancer center. Eur J Clin Microbiol Infect Dis 22:137-143
8. Velasco E, Byington R, Martins CAS, Schirmer M, Dias LCM, Gonçalves VMSC (2004) Bloodstream infections surveillance in a cancer center: a prospective look at clinical microbiology aspects. Clin Microbiol Infect 10:542-549
9. Garner JS, Jarvis WR, Emori TG, Horan TC, Hughes JM (1988) CDC definitions for nosocomial infections. Am J Infect Contr 16:128-140
10. Sickles E, Greene W, Wiernik PH (1975) Clinical presentation of infection in granulocytopenic patients. Arch Intern Med 135:715-719
11. Mermel LA, Farr BM, Sherertz RJ, Raad II, O'Grady N, Harris J, Craven DE (2001) Guidelines for management of intravascular catheter-related infections. Clin Infect Dis 32:1249-1272
12. Karnofsky DA, Burchenot JH (1949) The clinical evaluation of chemotherapeutic agents in cancer. In: MacLead CM (ed) Evaluation of chemotherapeutic agents. Symposium, Microbiology Section, New York Academy of Medicine, New York, New York, 1948. Columbia University Press, New York, pp 191-205
13. World Health Organization (1979) Handbook for reporting results of cancer treatment. WHO, Geneva, pp 15-22
14. Miller JM, O'Hara CM (1995) Substrate utilization systems for the identification of bacteria and yeast. In: Murray PR, Baron EJ, Pfaller MA, Tenover FC, Yolken RH (eds) Manual of clinical microbiology. American Society for Microbiology, Washington, District of Columbia, pp 103-109
15. National Committee for Clinical Laboratory Standards (2000) Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically. Approved standard M7-A5. NCCLS, Wayne, Pennsylvania
16. Klastersky J (2004) Management of fever in neutropenic patients with different risks of complications. Clin Infect Dis 39:S32-S37
17. Pompei P, Charlson ME, Ales K, MacKenzie CR, Norton M (1991) Relating patient characteristics at the time of admission to outcomes of hospitalization. J Clin Epidemiol 44:1063-1069
18. Elting L, Cooksley C, Chambers M, Cantor S, Manzullo E, Rubenstein E (2003) The burdens of cancer therapy: clinical and economic outcomes of chemotherapy-induced mucositis, measurement, epidemiology, and consequences for patients. Cancer 98:1531-1539
19. Diekema DJ, BootsMiller BJ, Vaughn TE, Woolson RF, Yankey JW, Ernst EJ, Flach SD, Ward MM, Franciscus CL, Pfaller MA, Doebbeling BN (2004) Antimicrobial resistance trends and outbreak frequency in United States hospitals. Clin Infect Dis 38:78-85
20. Winston DJ, Lazarus HM, Beveridge RA, Hathorn JW, Gucalp R, Ramphal R, Chow AW, Ho WG, Horn R, Feld R, Louie TJ, Territo MC, Blumer JL, Tack KJ (2001) Randomized, double-blind, multicenter trial comparing clinafloxacin with imipenem as empirical monotherapy for febrile granulocytopenic patients. Clin Infect Dis 32:381-390
21. Feld R, DePauw B, Berman S, Keating A, Ho W (2000) Meropenen versus ceftazidime in the treatment of cancer patients with febrile neutropenia: a randomized double-blind trial. J Clin Oncol 18:3690-3698
22. Extermann M (2000) Measuring comorbidity in older cancer patients. Eur J Cancer 36:453-471
23. Juthani-Mehta M, Quagliarello VJ (2004) Prognostic scoring system for infectious diseases: their applicability to the care of older adults. Clin Infect Dis 38:692-696
24. Rossini F (1996) Prognosis of infections in elderly patients with hematological diseases. Support Care Cancer 4:46-50
25. Cosgrove AS, Carmeli Y (2003) The impact of antimicrobial resistance on health and economic outcomes. Clin Infect Dis 36:1433-1437
26. Lautenbach E, Patel JB, Bilker WB, Edesltein PH, Fishman NO (2001) Extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae: risk factors for infection and impact of resistance on outcomes. Clin Infect Dis 32:1162-1171
27. Kang CI, Kim SH, Park WB, Lee KD, Kim HB, Oh Md, Kim EC, Choe KW (2004) Bloodstream infections caused by Enterobacter species: predictors of 30-day mortality rate and impact of broad-spectrum cephalosporin resistance on outcome. Clin Infect Dis 39:812-818
28. Vidal F, Mensa J, Almela M, Olona M, Martinez JA, Marco F, Lopez MJ, Soriano A, Horcajada JP, Gatell JM, Richart C (2003) Bacteraemia in adults due to glucose non-fermentative gram-negative bacilli other than P. aeruginosa. Q J Med 96:227-234
29. Martino R, Gomes L, Pericas R, Salazar R, Solá C, Sierra J, Garau J (2000) Bacteraemia caused by non-glucose fermenting gram-negative bacilli and Aeromonas species in patients with hematological malignancies and solid tumours. Eur J Clin Microbiol Infect Dis 19:320-323
30. Viscoli C, Girmenia C, Marinus A, Collete L, Martino P, Vandercam B, Doyen C, Lebeau B, Spence D, Krcmery V, De Pauw B, Meunier F, and the Invasive Fungal Infection Group of the EORTC (1999) Candidemia in cancer patients: a prospective, multicenter surveillance study by the Invasive Fungal Infection Group (IFIG) of the European Organization for Research and Treatment of Cancer (EORTC). Clin Infect Dis 28:1071-1079
31. Beck-Sagué CM, Jarvis WM, and the National Nosocomial Infections Surveillance System (1993) Secular trends in the epidemiology of nosocomial fungal infections in the United States, 1980-1990. J Infect Dis 167:1247-1251