B2 SINE retrotransposon causes polymorphic expression of mouse 5-aminolevulinic acid synthase 1 gene

Biochemical and Biophysical Research Communications

Volumn 377, Issue 2, 2008, Pages 515-520

  Chernova, Tatyana ^a   Higginson, Fiona M ^a   Davies, Reginald ^a   Smith, Andrew G ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

5 Aminolevulinic acid synthase 1; B2 SINE; Polymorphism; Promoter

Indexed keywords

5 AMINOLEVULINATE SYNTHASE; 5 AMINOLEVULINATE SYNTHASE 1; HEME; MESSENGER RNA; UNCLASSIFIED DRUG;

ALAS1 GENE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; C57BL 6 MOUSE; CONTROLLED STUDY; DBA 2 MOUSE; GENE; GENE CONTROL; GENE EXPRESSION; GENE REPRESSION; GENE SEQUENCE; GENETIC DIFFERENCE; GENETIC POLYMORPHISM; GENETIC TRANSCRIPTION; LIVER; LIVER CELL; MALE; MICROARRAY ANALYSIS; MOUSE; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; RETROPOSON; SHORT INTERSPERSED REPEAT; UNTRANSLATED REGION;

5' UNTRANSLATED REGIONS; 5-AMINOLEVULINATE SYNTHETASE; ANIMALS; BASE SEQUENCE; GENE EXPRESSION REGULATION; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; MOLECULAR SEQUENCE DATA; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; POLYMORPHISM, GENETIC; PROMOTER REGIONS, GENETIC; RETROELEMENTS;

MUS;

EID: 55549087533     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2008.10.020     Document Type: Article

References (29)

1. Furuyama K., Kaneko K., and Vargas P.D. Heme as a magnificent molecule with multiple missions: heme determines its own fate and governs cellular homeostasis. Tohoku J. Exp. Med. 213 (2007) 1-16
2. Gilles-Gonzalez M.A., and Gonzalez G. Heme-based sensors: defining characteristics, recent developments, and regulatory hypotheses. J. Inorg. Biochem. 99 (2005) 1-22
3. Hou S., Reynolds M.F., Horrigan F.T., Heinemann S.H., and Hoshi T. Reversible binding of heme to proteins in cellular signal transduction. Accounts Chem. Res. 39 (2006) 918-924
4. Chernova T., Steinert J.R., Guerin C.J., Nicotera P., Forsythe I.D., and Smith A.G. Neurite degeneration induced by heme deficiency mediated via inhibition of NMDA receptor-dependent extracellular signal-regulated kinase 1/2 activation. J. Neurosci. 27 (2007) 8475-8485
5. Faller M., Matsunaga M., Yin S., Loo J.A., and Guo F. Heme is involved in microRNA processing. Nat. Struct. Mol. Biol. 14 (2007) 23-29
6. Hu R.G., Wang H., Xia Z., and Varshavsky A. The N-end rule pathway is a sensor of heme. Proc. Natl. Acad. Sci. USA 105 (2008) 76-81
7. Roberts A.G., and Elder G.H. Alternative splicing, tissue-specific transcription of human and rodent ubiquitous 5-aminolevulinate synthase (ALAS1) genes. Biochim. Biophys. Acta 1518 (2001) 95-105
8. Zheng J., Tian Q., Hou W., Watts J.A., Schrum L.W., and Bonkovsky H.L. Tissue-specific expression of ALA synthase-1 and heme oxygenase-1 and their expression in livers of rats chronically exposed to ethanol. FEBS Lett. 582 (2008) 1829-1834
9. Kakizaki S., Yamamoto Y., Ueda A., Moore R., Sueyoshi T., and Negishi M. Phenobarbital induction of drug/steroid-metabolizing enzymes and nuclear receptor CAR. Biochim. Biophys. Acta 1619 (2003) 239-242
10. Fraser D.J., Zumsteg A., and Meyer U.A. Nuclear receptors constitutive androstane receptor and pregnane X receptor activate a drug-responsive enhancer of the murine 5-aminolevulinic acid synthase gene. J. Biol. Chem. 278 (2003) 39392-39401
11. Guberman A.S., Scassa M.E., Giono L.E., Varone C.L., and Canepa E.T. Inhibitory effect of AP-1 complex on 5-aminolevulinate synthase gene expression through sequestration of cAMP-response element protein (CRE)-binding protein (CBP) coactivator. J. Biol. Chem. 278 (2003) 2317-2326
12. Handschin C., Lin J., Rhee J., Peyer A.K., Chin S., Wu P.H., Meyer U.A., and Spiegelman B.M. Nutritional regulation of hepatic heme biosynthesis and porphyria through PGC-1alpha. Cell 122 (2005) 505-515
13. Kaasik K., and Lee C.C. Reciprocal regulation of haem biosynthesis and the circadian clock in mammals. Nature 430 (2004) 467-471
14. Claudio L., Lee T., Wolff M.S., and Wetmur J.G. A murine model of genetic susceptibility to lead bioaccumulation. Fundam. Appl. Toxicol. 35 (1997) 84-90
15. Robinson S.W., Clothier B., Akhtar R.A., Yang A.L., Latour I., Van Ijperen C., Festing M.F., and Smith A.G. Non-Ahr gene susceptibility loci for porphyria and liver injury induced by the interaction of 'dioxin' with iron overload in mice. Mol. Pharmacol. 61 (2002) 674-681
16. Gross S.R., and Hutton J.J. Induction of hepatic delta-aminolevulinic acid synthetase activity in strains of inbred mice. J. Biol. Chem. 246 (1971) 606-614
17. Goodrich J.A., and Kugel J.F. Non-coding-RNA regulators of RNA polymerase II transcription. Nat. Rev. Mol. Cell. Biol. 7 (2006) 612-616
18. Kalkkila J.P., Sharp F.R., Karkkainen I., Reilly M., Lu A., Solway K., Murrel M., and Honkaniemi J. Cloning and expression of short interspersed elements B1 and B2 in ischemic brain. Eur. J. Neurosci. 19 (2004) 1199-1206
19. Allen T.A., Von Kaenel S., Goodrich J.A., and Kugel J.F. The SINE-encoded mouse B2 RNA represses mRNA transcription in response to heat shock. Nat. Struct. Mol. Biol. 11 (2004) 816-821
20. Nishihara H., Smit A.F., and Okada N. Functional noncoding sequences derived from SINEs in the mammalian genome. Genome Res. 16 (2006) 864-874
21. Garcia-Trevijano E.R., Martinez-Chantar M.L., Latasa M.U., Mato J.M., and Avila M.A. NO sensitizes rat hepatocytes to proliferation by modifying S-adenosylmethionine levels. Gastroenterology 122 (2002) 1355-1363
22. Davies R., Clothier B., Robinson S.W., Edwards R.E., Greaves P., Luo J., Gant T.W., Chernova T., and Smith A.G. Essential role of the AH receptor in the dysfunction of heme metabolism induced by 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin. Chem. Res. Toxicol. 21 (2008) 330-340
23. Bennett K.L., Hill R.E., Pietras D.F., Woodworth-Gutai M., Kane-Haas C., Houston J.M., Heath J.K., and Hastie N.D. Most highly repeated dispersed DNA families in the mouse genome. Mol. Cell. Biol. 4 (1984) 1561-1571
24. Kramerov D.A., Tillib S.V., Ryskov A.P., and Georgiev G.P. Nucleotide sequence of small polyadenylated B2 RNA. Nucl. Acids Res. 13 (1985) 6423-6437
25. Dewannieux M., and Heidmann T. L1-mediated retrotransposition of murine B1 and B2 SINEs recapitulated in cultured cells. J. Mol. Biol. 349 (2005) 241-247
26. Espinoza C.A., Allen T.A., Hieb A.R., Kugel J.F., and Goodrich J.A. B2 RNA binds directly to RNA polymerase II to repress transcript synthesis. Nat. Struct. Mol. Biol. 11 (2004) 822-829
27. Espinoza C.A., Goodrich J.A., and Kugel J.F. Characterization of the structure, function, and mechanism of B2 RNA, an ncRNA repressor of RNA polymerase II transcription. RNA 13 (2007) 583-596
28. Roman A.C., Benitez D.A., Carvajal-Gonzalez J.M., and Fernandez-Salguero P.M. Genome-wide B1 retrotransposon binds the transcription factors dioxin receptor and Slug and regulates gene expression in vivo. Proc. Natl. Acad. Sci. USA 105 (2008) 1632-1637
29. Kettenberger H., Eisenfuhr A., Brueckner F., Theis M., Famulok M., and Cramer P. Structure of an RNA polymerase II-RNA inhibitor complex elucidates transcription regulation by noncoding RNAs. Nat. Struct. Mol. Biol. 13 (2006) 44-48