Role of the transgenic human thyrotropin receptor A-subunit in thyroiditis induced by A-subunit immunization and regulatory T cell depletion

Clinical and Experimental Immunology

Volumn 154, Issue 3, 2008, Pages 305-315

  Mizutori, Y ^b   Nagayama, Y ^c   Flower, D ^d   Misharin, A ^b   Aliesky, H A ^b   Rapoport, B ^b   McLachlan, S M ^a,b  

^a CEDARS SINAI MEDICAL CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c NAGASAKI UNIVERSITY   (Japan)

^d UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Regulatory T cells; Thyroid infiltration; TSHR antibody epitopes; TSHR T cell epitopes; TSHR transgenic mice

Indexed keywords

AMINO TERMINAL TELOPEPTIDE; AUTOANTIGEN; C PEPTIDE; EPITOPE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MESSENGER RNA; RECEPTOR ANTIBODY; RECEPTOR SUBUNIT; THYROTROPIN RECEPTOR; VIRUS VACCINE;

ADENOVIRUS; AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNIZATION; LYMPHOCYTE DEPLETION; LYMPHOCYTIC INFILTRATION; MOLECULAR RECOGNITION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; REGULATORY T LYMPHOCYTE; THYROIDITIS; TRANSGENIC MOUSE;

AMINO ACID SEQUENCE; ANIMALS; AUTOANTIBODIES; AUTOANTIGENS; CHEMOTAXIS, LEUKOCYTE; EPITOPES, T-LYMPHOCYTE; HUMANS; IMMUNIZATION; LYMPHOCYTE DEPLETION; MICE; MICE, INBRED BALB C; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; RECEPTORS, THYROTROPIN; RNA, MESSENGER; SPLEEN; T-LYMPHOCYTES, REGULATORY; THYROID GLAND; THYROIDITIS, AUTOIMMUNE;

EID: 55449125467     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/j.1365-2249.2008.03769.x     Document Type: Article

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