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Volumn 30, Issue 6, 2008, Pages 391-411

Stratum corneum lipid organization as observed by atomic force, confocal and two-photon excitation fluorescence microscopy

Author keywords

AFM; Ceramides; Skin barrier; Skin lipids; Skin permeability; TPE fluorescence microscopy

Indexed keywords

CERAMIDE; CHOLESTEROL; SKIN LIPID;

EID: 55449093260     PISSN: 01425463     EISSN: 14682494     Source Type: Journal    
DOI: 10.1111/j.1468-2494.2008.00458.x     Document Type: Review
Times cited : (29)

References (77)
  • 1
    • 76949135974 scopus 로고
    • Factors which influence the water content of stratum corneum
    • Blank, I.H. Factors which influence the water content of stratum corneum. J. Invest. Dermatol. 18, 433 440 (1952).
    • (1952) J. Invest. Dermatol. , vol.18 , pp. 433-440
    • Blank, I.H.1
  • 2
    • 0016545625 scopus 로고
    • Drug permeation through human skin: Theory and in vitro experimental measurements
    • Michaels, A.S., Chandrasekaran, S.K. Shaw, J.E. Drug permeation through human skin: theory and in vitro experimental measurements. AIChE J. 21, 985 996 (1975).
    • (1975) AIChE J. , vol.21 , pp. 985-996
    • Michaels, A.S.1    Chandrasekaran, S.K.2    Shaw, J.E.3
  • 3
    • 0027955474 scopus 로고
    • A domain mosaic model of the skin barrier
    • Forslind, B. A domain mosaic model of the skin barrier. Acta Derm. Venereol. 74, 1 6 (1994).
    • (1994) Acta Derm. Venereol. , vol.74 , pp. 1-6
    • Forslind, B.1
  • 4
    • 0034778702 scopus 로고    scopus 로고
    • Skin barrier structure and function: The single gel-phase model
    • Norlén, L. Skin barrier structure and function: the single gel-phase model. J. Invest. Dermatol. 117, 830 836 (2001).
    • (2001) J. Invest. Dermatol. , vol.117 , pp. 830-836
    • Norlén, L.1
  • 5
    • 0036091146 scopus 로고    scopus 로고
    • Does the single gel-phase exist in stratum corneum?
    • Bouwstra, J.A., Pilgram, G. Ponec, M. Does the single gel-phase exist in stratum corneum? J. Invest. Dermatol. 118, 897 898 (2002).
    • (2002) J. Invest. Dermatol. , vol.118 , pp. 897-898
    • Bouwstra, J.A.1    Pilgram, G.2    Ponec, M.3
  • 6
    • 0036091146 scopus 로고    scopus 로고
    • Does the single gel-phase exist in stratum corneum?
    • Reply.
    • Norlén, L. Does the single gel-phase exist in stratum corneum? Reply. J. Invest. Dermatol. 118, 899 901 (2002).
    • (2002) J. Invest. Dermatol. , vol.118 , pp. 899-901
    • Norlén, L.1
  • 7
    • 36049033182 scopus 로고    scopus 로고
    • Direct visualization of lipid domains in human skin stratum corneum's lipid membranes: Effect of pH and temperature
    • Plasencia, I., Norlén, L. Bagatolli, L.A. Direct visualization of lipid domains in human skin stratum corneum's lipid membranes: effect of pH and temperature. Biophysical J. 93, 3142 3155 (2007).
    • (2007) Biophysical J. , vol.93 , pp. 3142-3155
    • Plasencia, I.1    Norlén, L.2    Bagatolli, L.A.3
  • 8
    • 34248579896 scopus 로고    scopus 로고
    • Human stratum corneum lipid organization as observed by atomic force microscopy on Langmuir-Blodgett films
    • Norlén, L., Plasencia, I., Simonsen, A. Descouts, P. Human stratum corneum lipid organization as observed by atomic force microscopy on Langmuir-Blodgett films. J. Struct. Biol. 158, 386 400 (2007).
    • (2007) J. Struct. Biol. , vol.158 , pp. 386-400
    • Norlén, L.1    Plasencia, I.2    Simonsen, A.3    Descouts, P.4
  • 9
    • 70449328477 scopus 로고
    • Macromolecular organization of epidermal keratin: An x-ray diffraction study of the horny layer from normal, ichthyotic and psoriatic skin
    • Swanbeck, G. Macromolecular organization of epidermal keratin: an x-ray diffraction study of the horny layer from normal, ichthyotic and psoriatic skin. Acta Derm. Venereol. Suppl. (Stockh) 39 (Suppl. 43 1 37 (1959b).
    • (1959) Acta Derm. Venereol. Suppl. (Stockh) , vol.39 , Issue.43 , pp. 1-37
    • Swanbeck, G.1
  • 10
    • 0014944572 scopus 로고
    • Uniquely oriented epidermal lipid
    • Goldsmith, L.A. Baden, H.P. Uniquely oriented epidermal lipid. Nature 225, 1052 1053 (1970).
    • (1970) Nature , vol.225 , pp. 1052-1053
    • Goldsmith, L.A.1    Baden, H.P.2
  • 11
    • 0015938086 scopus 로고
    • Structure-property relations of human and neonatal rat stratum corneum. I. Thermal stability of the crystalline lipid structure as studied by x-ray diffraction and differential thermal analysis
    • Wilkes, G.L., Nguyen, A.L. Wildnauer, R. Structure-property relations of human and neonatal rat stratum corneum. I. Thermal stability of the crystalline lipid structure as studied by x-ray diffraction and differential thermal analysis. Biochim. Biophys. Acta 304, 267 275 (1973).
    • (1973) Biochim. Biophys. Acta , vol.304 , pp. 267-275
    • Wilkes, G.L.1    Nguyen, A.L.2    Wildnauer, R.3
  • 12
    • 0024290394 scopus 로고
    • Structure of lamellar lipid domains and corneocyte envelopes of murine stratum corneum. An X-ray diffraction study
    • White, S.H., Mirejovsky, D. King, G.I. Structure of lamellar lipid domains and corneocyte envelopes of murine stratum corneum. An X-ray diffraction study. Biochemistry 27, 3725 3732 (1988).
    • (1988) Biochemistry , vol.27 , pp. 3725-3732
    • White, S.H.1    Mirejovsky, D.2    King, G.I.3
  • 13
    • 0025955486 scopus 로고
    • Structural investigations of human stratum corneum by small-angle x-ray scattering
    • Bouwstra, J.A., Gooris, G.S., Van der Spek, J.A. Bras, W. Structural investigations of human stratum corneum by small-angle x-ray scattering. J. Invest. Dermatol. 97, 1005 1012 (1991).
    • (1991) J. Invest. Dermatol. , vol.97 , pp. 1005-1012
    • Bouwstra, J.A.1    Gooris, G.S.2    Van Der Spek, J.A.3    Bras, W.4
  • 14
  • 15
    • 0026669010 scopus 로고
    • Structure of human stratum corneum as a function of temperature and hydration: A wide-angle x-ray diffraction study
    • Bouwstra, J.A., Gooris, G.S., Salmon-de Vries, M.A., Van der Spek, J.A. Bras, W. Structure of human stratum corneum as a function of temperature and hydration: a wide-angle x-ray diffraction study. Int. J. Pharmaceut. 84, 205 216 (1992).
    • (1992) Int. J. Pharmaceut. , vol.84 , pp. 205-216
    • Bouwstra, J.A.1    Gooris, G.S.2    Salmon-De Vries, M.A.3    Van Der Spek, J.A.4    Bras, W.5
  • 16
    • 33750506097 scopus 로고    scopus 로고
    • Coexistence of two domains in intercellular lipid matrix of stratum corneum
    • Hatta, I., Ohta, N., Inoue, K. Yagi, N. Coexistence of two domains in intercellular lipid matrix of stratum corneum. Biochim. Biophys. Acta 1758, 1830 1836 (2006).
    • (2006) Biochim. Biophys. Acta , vol.1758 , pp. 1830-1836
    • Hatta, I.1    Ohta, N.2    Inoue, K.3    Yagi, N.4
  • 17
    • 0032833887 scopus 로고    scopus 로고
    • Electron diffraction provides new information on human stratum corneum lipid organization studied in relation to depth and temperature
    • Pilgram, G.S.K., Engelsma-van Pelt, A.M., Bouwstra, J.A. Koerten, H.K. Electron diffraction provides new information on human stratum corneum lipid organization studied in relation to depth and temperature. J. Invest. Dermatol. 113, 101 107 (1999).
    • (1999) J. Invest. Dermatol. , vol.113 , pp. 101-107
    • Pilgram, G.S.K.1    Engelsma-Van Pelt, A.M.2    Bouwstra, J.A.3    Koerten, H.K.4
  • 19
    • 15444370672 scopus 로고    scopus 로고
    • Nanostructure of the epidermal extracellular space as observed by cryo-electron microscopy of vitreous sections of human skin
    • Al-Amoudi, A., Dubochet, J. Norlén, L. Nanostructure of the epidermal extracellular space as observed by cryo-electron microscopy of vitreous sections of human skin. J. Invest. Dermatol. 124, 764 777 (2005).
    • (2005) J. Invest. Dermatol. , vol.124 , pp. 764-777
    • Al-Amoudi, A.1    Dubochet, J.2    Norlén, L.3
  • 22
    • 0031672087 scopus 로고    scopus 로고
    • A new HPLC-based method for the quantitative analysis of inner stratum corneum lipids with special reference to the free fatty acid fraction
    • Norlén, L., Nicander, I., Lundsjö, A., Cronholm, T. Forslind, B. A new HPLC-based method for the quantitative analysis of inner stratum corneum lipids with special reference to the free fatty acid fraction. Arch. Derm. Res. 290, 508 516 (1998).
    • (1998) Arch. Derm. Res. , vol.290 , pp. 508-516
    • Norlén, L.1    Nicander, I.2    Lundsjö, A.3    Cronholm, T.4    Forslind, B.5
  • 23
    • 85056937254 scopus 로고    scopus 로고
    • "confidence intervals" for the "true" lipid composition of the human skin barrier
    • In: Forslind, B. Lindberg, M., eds), pp. Marcel Dekker, New York (
    • Wertz, P. Norlén, L. "Confidence intervals" for the "true" lipid composition of the human skin barrier. In: Skin, Hair and Nails - Structure and Function (Forslind, B. Lindberg, M., eds), pp. 85 106. Marcel Dekker, New York (2003).
    • (2003) Skin, Hair and Nails - Structure and Function , pp. 85-106
    • Wertz, P.1    Norlén, L.2
  • 26
    • 30844463224 scopus 로고    scopus 로고
    • Lipid mixtures with well-defined synthetic ceramides closely mimic the unique stratum corneum lipid phase behaviour
    • de Jager, M.W., Gooris, G.S., Ponec, M. Bouwstra, J.A. Lipid mixtures with well-defined synthetic ceramides closely mimic the unique stratum corneum lipid phase behaviour. J. Lipid Res. 46, 2649 2656 (2005).
    • (2005) J. Lipid Res. , vol.46 , pp. 2649-2656
    • De Jager, M.W.1    Gooris, G.S.2    Ponec, M.3    Bouwstra, J.A.4
  • 27
    • 0000752198 scopus 로고
    • Studies of the relationship between bilayer water permeability and bilayer physical state
    • Carruthers, A. Melchior, D.L. Studies of the relationship between bilayer water permeability and bilayer physical state. Biochemistry 22, 5797 5807 (1983).
    • (1983) Biochemistry , vol.22 , pp. 5797-5807
    • Carruthers, A.1    Melchior, D.L.2
  • 28
    • 0002408506 scopus 로고    scopus 로고
    • Infrared spectroscopy and differential scanning calorimetric investigations of the stratum corneum barrier function
    • In: Potts, R.O. Guy, R.H., eds), pp. Marcel Dekker, New York (
    • Naik, A. Guy, R.H. Infrared spectroscopy and differential scanning calorimetric investigations of the stratum corneum barrier function. In: Mechanisms of Transdermal Drug Delivery (Potts, R.O. Guy, R.H., eds), pp. 87 162 Marcel Dekker, New York (1997).
    • (1997) Mechanisms of Transdermal Drug Delivery , pp. 87-162
    • Naik, A.1    Guy, R.H.2
  • 29
    • 0041621569 scopus 로고    scopus 로고
    • PH directly regulates epidermal permeability barrier homeostasis, and stratum corneum integrity/cohesion
    • Hachem, J.-P., Crumrine, D., Fluhr, J., Feingold, K.R. Elias, P.M. pH directly regulates epidermal permeability barrier homeostasis, and stratum corneum integrity/cohesion. J. Invest. Dermatol. 121, 345 353 (2003).
    • (2003) J. Invest. Dermatol. , vol.121 , pp. 345-353
    • Hachem, J.-P.1    Crumrine, D.2    Fluhr, J.3    Feingold, K.R.4    Elias, P.M.5
  • 31
    • 0038806397 scopus 로고    scopus 로고
    • Neonatal development of the stratum corneum pH gradient: Localization and mechanisms leading to emergence of optimal barrier function
    • Behne, M.J., Barry, N.P., Hanson, K.M. et al. Neonatal development of the stratum corneum pH gradient: localization and mechanisms leading to emergence of optimal barrier function. J. Invest. Dermatol. 120, 998 1006 (2003).
    • (2003) J. Invest. Dermatol. , vol.120 , pp. 998-1006
    • Behne, M.J.1    Barry, N.P.2    Hanson, K.M.3
  • 32
    • 3042646598 scopus 로고    scopus 로고
    • Functional consequences of a neutral pH in neonatal rat stratum corneum
    • Fluhr, J.W., Man, M.-Q., Brown, B.E. et al. Functional consequences of a neutral pH in neonatal rat stratum corneum. J. Invest. Dermatol. 123, 140 151 (2004).
    • (2004) J. Invest. Dermatol. , vol.123 , pp. 140-151
    • Fluhr, J.W.1    Man, M.-Q.2    Brown, B.E.3
  • 33
    • 0021954377 scopus 로고
    • Transepidermal water loss in dry and clinically normal skin in patients with atopic dermatitis
    • Werner, Y. Lindberg, M. Transepidermal water loss in dry and clinically normal skin in patients with atopic dermatitis. Acta Derm. Venereol. 65, 102 105 (1985).
    • (1985) Acta Derm. Venereol. , vol.65 , pp. 102-105
    • Werner, Y.1    Lindberg, M.2
  • 34
    • 0033816813 scopus 로고    scopus 로고
    • Skin surface pH, stratum corneum hydration, trans-epidermal water loss and skin roughness related to atopic eczema and skin dryness in a population of primary school children
    • Eberlein-Konig, B., Schafer, T., Huss-Marp, J. et al. Skin surface pH, stratum corneum hydration, trans-epidermal water loss and skin roughness related to atopic eczema and skin dryness in a population of primary school children. Acta Derm. Venereol. 80, 188 191 (2000).
    • (2000) Acta Derm. Venereol. , vol.80 , pp. 188-191
    • Eberlein-Konig, B.1    Schafer, T.2    Huss-Marp, J.3
  • 35
    • 26444570089 scopus 로고    scopus 로고
    • Sustained serine proteases activity by prolonged increase in pH leads to degradation of lipid processing enzymes and profound alterations of barrier function and stratum corneum integrity
    • Hachem, J.-P., Man, M.-Q., Crumrine, D. et al. Sustained serine proteases activity by prolonged increase in pH leads to degradation of lipid processing enzymes and profound alterations of barrier function and stratum corneum integrity. J. Invest. Dermatol. 125, 510 520 (2005).
    • (2005) J. Invest. Dermatol. , vol.125 , pp. 510-520
    • Hachem, J.-P.1    Man, M.-Q.2    Crumrine, D.3
  • 36
    • 0031687460 scopus 로고    scopus 로고
    • The pH gradient over the stratum corneum differs in x-linked recessive and autosomal dominant ichtyosis: A clue to the molecular origin of the "acid skin mantle"?
    • Öhman, H. Vahlquist, A. The pH gradient over the stratum corneum differs in x-linked recessive and autosomal dominant ichtyosis: a clue to the molecular origin of the "acid skin mantle"? J. Invest. Dermatol. 111, 674 677 (1998).
    • (1998) J. Invest. Dermatol. , vol.111 , pp. 674-677
    • Öhman, H.1    Vahlquist, A.2
  • 37
    • 33751329990 scopus 로고    scopus 로고
    • The pH of the skin surface and its impact on the barrier function
    • Schmid-Wendtner, M.-H. Korting, H.C. The pH of the skin surface and its impact on the barrier function. Skin Pharmacol. Physiol. 19, 296 302 (2006).
    • (2006) Skin Pharmacol. Physiol. , vol.19 , pp. 296-302
    • Schmid-Wendtner, M.-H.1    Korting, H.C.2
  • 38
    • 0017569104 scopus 로고
    • Skin barrier properties in the newborn. Transepidermal water and carbon dioxide emission rates
    • Cunico, R.L., Maibach, H.I., Khan, H. Bloom, E. Skin barrier properties in the newborn. Transepidermal water and carbon dioxide emission rates. Biol. Neonate 32, 177 182 (1977).
    • (1977) Biol. Neonate , vol.32 , pp. 177-182
    • Cunico, R.L.1    Maibach, H.I.2    Khan, H.3    Bloom, E.4
  • 39
    • 0028280354 scopus 로고
    • Association of skin wetness and pH with diaper dermatitis
    • Berg, R.W., Milligan, M.C. Sarbaugh, F.C. Association of skin wetness and pH with diaper dermatitis. Pediatr. Dermatol. 11, 18 20 (1994).
    • (1994) Pediatr. Dermatol. , vol.11 , pp. 18-20
    • Berg, R.W.1    Milligan, M.C.2    Sarbaugh, F.C.3
  • 41
    • 0032865852 scopus 로고    scopus 로고
    • A new computer-based evaporimeter system for rapid measuerments of water diffusion through stratum corneum in vitro
    • Norlén, L., Engblom, J., Anderson, M. Forslind, B. A new computer-based evaporimeter system for rapid measuerments of water diffusion through stratum corneum in vitro. J. Invest. Dermatol. 113, 533 540 (1999b).
    • (1999) J. Invest. Dermatol. , vol.113 , pp. 533-540
    • Norlén, L.1    Engblom, J.2    Anderson, M.3    Forslind, B.4
  • 42
    • 0034720465 scopus 로고    scopus 로고
    • Visual imaging of ion distribution in human epidermis
    • Denda, M., Hosoi, J. Asida, Y. Visual imaging of ion distribution in human epidermis. Biochem. Biophys. Res. Commun. 272, 134 137 (2000).
    • (2000) Biochem. Biophys. Res. Commun. , vol.272 , pp. 134-137
    • Denda, M.1    Hosoi, J.2    Asida, Y.3
  • 43
    • 0028094570 scopus 로고
    • In vivo studies concerning a pH gradient in human stratum corneum and upper epidermis
    • Öhman, H. Vahlquist, A. In vivo studies concerning a pH gradient in human stratum corneum and upper epidermis. Acta Derm. Venerol. 74, 375 379 (1994).
    • (1994) Acta Derm. Venerol. , vol.74 , pp. 375-379
    • Öhman, H.1    Vahlquist, A.2
  • 44
    • 0036708473 scopus 로고    scopus 로고
    • Two-photon fluorescence lifetime imaging of the skin stratum corneum pH gradient
    • Hanson, K.M., Behne, M.J., Barry, N.P., Mauro, T., Gratton, E. Clegg, R.M. Two-photon fluorescence lifetime imaging of the skin stratum corneum pH gradient. Biophys. J. 83, 1682 1690 (2002).
    • (2002) Biophys. J. , vol.83 , pp. 1682-1690
    • Hanson, K.M.1    Behne, M.J.2    Barry, N.P.3    Mauro, T.4    Gratton, E.5    Clegg, R.M.6
  • 45
    • 0037452646 scopus 로고    scopus 로고
    • Modulation of the polymorphism of the palmitic acid/cholesterol system by pH
    • Ouimet, J., Croft, S., Paré, C., Katsaras, J. Lafleur, M. Modulation of the polymorphism of the palmitic acid/cholesterol system by pH. Langmuir 19, 1089 1097 (2003).
    • (2003) Langmuir , vol.19 , pp. 1089-1097
    • Ouimet, J.1    Croft, S.2    Paré, C.3    Katsaras, J.4    Lafleur, M.5
  • 46
    • 18144423564 scopus 로고    scopus 로고
    • Decoupled phase transitions and grain-boundary melting in supported phospholipid bilayers
    • 025701
    • Keller, D., Larsen, N.B., Möller, I.M. Mouritsen, O.G. Decoupled phase transitions and grain-boundary melting in supported phospholipid bilayers. Phys. Rev. Lett. 94, 025701 (2005).
    • (2005) Phys. Rev. Lett.
    • Keller, D.1    Larsen, N.B.2    Möller, I.M.3    Mouritsen, O.G.4
  • 48
    • 55449097933 scopus 로고    scopus 로고
    • Sebum
    • In: Elsner, P. Maibach, H.I., eds), pp. Marcel Deker Inc., New York (
    • Wertz, P.W. Michniak, B.B. Sebum. In: Cosmeceuticals (Elsner, P. Maibach, H.I., eds), pp. 45 56. Marcel Deker Inc., New York (2000).
    • (2000) Cosmeceuticals , pp. 45-56
    • Wertz, P.W.1    Michniak, B.B.2
  • 50
    • 27144445099 scopus 로고    scopus 로고
    • Profiling of human stratum corneum ceramides by means of normal phase LC/APCI-MS
    • Farwanah, H., Wohlrab, J., Neubert, R.H.H. Raith, K. Profiling of human stratum corneum ceramides by means of normal phase LC/APCI-MS. Anal. Bioanal. Chem. 383, 632 637 (2005).
    • (2005) Anal. Bioanal. Chem. , vol.383 , pp. 632-637
    • Farwanah, H.1    Wohlrab, J.2    Neubert, R.H.H.3    Raith, K.4
  • 51
    • 0344334363 scopus 로고    scopus 로고
    • Inter and intra individual differences in human stratum corneum lipid content related to physical parameters of skin barrier function
    • Norlén, L., Nicander, I., Lundh-Rozell, B., Ollmar, S. Forslind, B. Inter and intra individual differences in human stratum corneum lipid content related to physical parameters of skin barrier function. J. Invest. Dermatol. 112, 72 77 (1999).
    • (1999) J. Invest. Dermatol. , vol.112 , pp. 72-77
    • Norlén, L.1    Nicander, I.2    Lundh-Rozell, B.3    Ollmar, S.4    Forslind, B.5
  • 52
    • 0037278149 scopus 로고    scopus 로고
    • Direct observation of lipid domains in free standing bilayers: From simple to complex lipid mixtures
    • Bagatolli, L.A. Direct observation of lipid domains in free standing bilayers: from simple to complex lipid mixtures. Chem. Phys. Lipids, 122, 137 145 (2003).
    • (2003) Chem. Phys. Lipids , vol.122 , pp. 137-145
    • Bagatolli, L.A.1
  • 53
    • 33749046710 scopus 로고    scopus 로고
    • To see or not to see: Lateral organization of biological membranes and fluorescent microscopy
    • Bagatolli, L.A. To see or not to see: lateral organization of biological membranes and fluorescent microscopy. Biochim. Biophys. Acta 1758, 1541 1556 (2006).
    • (2006) Biochim. Biophys. Acta , vol.1758 , pp. 1541-1556
    • Bagatolli, L.A.1
  • 56
    • 0033972990 scopus 로고    scopus 로고
    • Rectangular solid domains in ceramide-cholesterol monolayer-2D crystals
    • Ekelund, K., Eriksson, L. Sparr, E. Rectangular solid domains in ceramide-cholesterol monolayer-2D crystals. Biochim. Biophys. Acta 1464, 1 6 (2000).
    • (2000) Biochim. Biophys. Acta , vol.1464 , pp. 1-6
    • Ekelund, K.1    Eriksson, L.2    Sparr, E.3
  • 57
    • 0035124536 scopus 로고    scopus 로고
    • AFM study of lipid monolayers: III. Phase behavior of ceramides, cholesterol and fatty acids
    • Sparr, E., Eriksson, L., Bouwstra, J.A. Ekelund, K. AFM study of lipid monolayers: III. Phase behavior of ceramides, cholesterol and fatty acids. Langmuir 17, 164 172 (2001).
    • (2001) Langmuir , vol.17 , pp. 164-172
    • Sparr, E.1    Eriksson, L.2    Bouwstra, J.A.3    Ekelund, K.4
  • 58
    • 0033114650 scopus 로고    scopus 로고
    • Structure and phase transitions in Langmuir monolayers
    • Kaganer, V.M., Möhwald, H. Dutta, P. Structure and phase transitions in Langmuir monolayers. Rev. Mod. Phys. 71, 779 819 (1999).
    • (1999) Rev. Mod. Phys. , vol.71 , pp. 779-819
    • Kaganer, V.M.1    Möhwald, H.2    Dutta, P.3
  • 59
    • 0028514315 scopus 로고
    • Steady state morphology and composition of mixed monomolecular films (Langmuir monolayers) at the air/water interface in the vicinity of the three-phase line: Model calculations and experiments
    • Spratte, K. Riegler, H. Steady state morphology and composition of mixed monomolecular films (Langmuir monolayers) at the air/water interface in the vicinity of the three-phase line: model calculations and experiments. Langmuir 10, 1361 3173 (1994).
    • (1994) Langmuir , vol.10 , pp. 1361-3173
    • Spratte, K.1    Riegler, H.2
  • 60
    • 0028529767 scopus 로고
    • Metastability in monolayer films transferred onto solid substrates by the Langmuir-Blodgett method: IR evidence for transfer-induced phase transitions
    • Rana, F.R., Widayati, S., Gregory, B.W. Dluhy, R.A. Metastability in monolayer films transferred onto solid substrates by the Langmuir-Blodgett method: IR evidence for transfer-induced phase transitions. Appl. Spectrosc. 48, 1196 1203 (1994).
    • (1994) Appl. Spectrosc. , vol.48 , pp. 1196-1203
    • Rana, F.R.1    Widayati, S.2    Gregory, B.W.3    Dluhy, R.A.4
  • 61
    • 0031210519 scopus 로고    scopus 로고
    • A temperature dependent two-dimensional condensation transition during Langmuir-Blodgett deposition
    • Sikes, H.D. Schwartz, D.K. A temperature dependent two-dimensional condensation transition during Langmuir-Blodgett deposition. Langmuir 13, 4704 4709 (1997).
    • (1997) Langmuir , vol.13 , pp. 4704-4709
    • Sikes, H.D.1    Schwartz, D.K.2
  • 63
    • 0000138260 scopus 로고    scopus 로고
    • Direct observation of lipid domains in free standing bilayers using two-photon excitation fluorescence microscopy
    • Bagatolli, L.A. Gratton, E. Direct observation of lipid domains in free standing bilayers using two-photon excitation fluorescence microscopy. J. Fluoresc. 11, 141 160 (2001).
    • (2001) J. Fluoresc. , vol.11 , pp. 141-160
    • Bagatolli, L.A.1    Gratton, E.2
  • 64
    • 3142643268 scopus 로고    scopus 로고
    • Laurdan and Prodan as polarity sensitive fluorescence membrane probes
    • Parasassi, T.E.K., Krasnowska, L.A., Bagatolli, L. Gratton, E. Laurdan and Prodan as polarity sensitive fluorescence membrane probes. J. Fluoresc. 8, 365 373 (1998).
    • (1998) J. Fluoresc. , vol.8 , pp. 365-373
    • Parasassi, T.E.K.1    Krasnowska, L.A.2    Bagatolli, L.3    Gratton, E.4
  • 65
    • 0025342635 scopus 로고
    • Two-photon laser scanning fluorescence microscopy
    • Denk, W., Strickler, J.H. Webb, W.W. Two-photon laser scanning fluorescence microscopy. Science 248, 73 76 (1990).
    • (1990) Science , vol.248 , pp. 73-76
    • Denk, W.1    Strickler, J.H.2    Webb, W.W.3
  • 67
    • 0033450351 scopus 로고    scopus 로고
    • Multi-photon excitation microscopy and confocal microscopy imaging of in vivo human skin: A comparison
    • Masters, B.R. So, P.T.C. Multi-photon excitation microscopy and confocal microscopy imaging of in vivo human skin: a comparison. Microsc. Microanal. 5, 282 289 (1999).
    • (1999) Microsc. Microanal. , vol.5 , pp. 282-289
    • Masters, B.R.1    So, P.T.C.2
  • 68
    • 0141644208 scopus 로고    scopus 로고
    • High-resolution multiphoton tomography of human skin with subcellular spatial resolution and picosecond time resolution
    • Konig, K. Riemann, I. High-resolution multiphoton tomography of human skin with subcellular spatial resolution and picosecond time resolution. J. Biomed. Opt. 8, 432 439 (2003).
    • (2003) J. Biomed. Opt. , vol.8 , pp. 432-439
    • Konig, K.1    Riemann, I.2
  • 69
    • 0037795542 scopus 로고    scopus 로고
    • Live tissue intrinsic emission microscopy using multiphoton-excited native fluorescence and second harmonic generation
    • Zipfel, W.R., Williams, R.M., Christie, R., Nikitin, A.Y., Hyman, B.T. Webb, W.W. Live tissue intrinsic emission microscopy using multiphoton-excited native fluorescence and second harmonic generation. Proc. Natl Acad. Sci. USA 100, 7075 7080 (2003).
    • (2003) Proc. Natl Acad. Sci. USA , vol.100 , pp. 7075-7080
    • Zipfel, W.R.1    Williams, R.M.2    Christie, R.3    Nikitin, A.Y.4    Hyman, B.T.5    Webb, W.W.6
  • 71
    • 0028040472 scopus 로고
    • Characterization of low-temperature (i.e., < 65 degrees C) lipid transitions in human stratum corneum
    • Gay, C.L., Guy, R.H., Golden, G.M., Mak, V.H. Francoeur, M.L. Characterization of low-temperature (i.e., < 65 degrees C) lipid transitions in human stratum corneum. J. Invest. Dermatol. 103, 233 239 (1994).
    • (1994) J. Invest. Dermatol. , vol.103 , pp. 233-239
    • Gay, C.L.1    Guy, R.H.2    Golden, G.M.3    Mak, V.H.4    Francoeur, M.L.5
  • 72
    • 34147191465 scopus 로고    scopus 로고
    • Infrared spectroscopic study of stratum corneum model membranes prepared from human ceramides, cholesterol and fatty acids
    • Gooris, G. Bouwstra, J. Infrared spectroscopic study of stratum corneum model membranes prepared from human ceramides, cholesterol and fatty acids. Biophys. J. 92, 2785 2795 (2007).
    • (2007) Biophys. J. , vol.92 , pp. 2785-2795
    • Gooris, G.1    Bouwstra, J.2
  • 73
    • 33644990077 scopus 로고    scopus 로고
    • Thermotropic and spectroscopic behavior of skin: Relationship with percutaneous permeation enhancement
    • Babita, K., Kumar, V., Rana, V., Jain, S. Tiwary, A.K. Thermotropic and spectroscopic behavior of skin: relationship with percutaneous permeation enhancement. Curr. Drug. Deliv. 3, 95 113 (2006).
    • (2006) Curr. Drug. Deliv. , vol.3 , pp. 95-113
    • Babita, K.1    Kumar, V.2    Rana, V.3    Jain, S.4    Tiwary, A.K.5
  • 74
    • 33845308573 scopus 로고    scopus 로고
    • The skin barrier in healthy and diseased state
    • Bouwstra, J.A. Ponec, M. The skin barrier in healthy and diseased state. Biochim Biophys. Acta 1758, 2080 2095 (2006).
    • (2006) Biochim Biophys. Acta , vol.1758 , pp. 2080-2095
    • Bouwstra, J.A.1    Ponec, M.2
  • 77
    • 0029415097 scopus 로고
    • Apparent pKa of the fatty acids within ordered mixtures of model human stratum corneum lipids
    • Lieckfeldt, R., Villalain, J., Gomez-Fernandez, J.C. Lee, G. Apparent pKa of the fatty acids within ordered mixtures of model human stratum corneum lipids. Pharm. Res. 12, 1614 1617 (1995).
    • (1995) Pharm. Res. , vol.12 , pp. 1614-1617
    • Lieckfeldt, R.1    Villalain, J.2    Gomez-Fernandez, J.C.3    Lee, G.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.