Association study between adolescent idiopathic scoliosis and the DPP9 gene which is located in the candidate region identified by linkage analysis

Postgraduate Medical Journal

Volumn 84, Issue 995, 2008, Pages 498-501

  Qiu, X S ^a,b   Tang, N L S ^b   Yeung, H Y ^b   Qiu, Y ^a   Cheng, J C Y ^b,c  

^a MEDICAL SCHOOL OF NANJING UNIVERSITY   (China)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^c CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

DIPEPTIDYL PEPTIDASE; DIPEPTIDYL PEPTIDASE 9; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE SEVERITY; FEMALE; GENE FREQUENCY; GENE LOCATION; GENE SEQUENCE; HUMAN; IDIOPATHIC SCOLIOSIS; LINKAGE ANALYSIS; MAJOR CLINICAL STUDY; POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SCHOOL CHILD;

EID: 55349119886     PISSN: 00325473     EISSN: 14690756     Source Type: Journal    
DOI: 10.1136/pgmj.2007.066639     Document Type: Article

References (34)

1. Rogala EJ, Drummond DS, Gurr J. Scoliosis incidence and natural history: a prospective epidemiological study. J Bone Joint Surg Am 1976;60:173-6.
2. Lowe TG, Edgar M, Margulies JY, et al. Etiology of idiopathic scoliosis: current trends in research. J Bone Joint Surg Am 2000;82:1157-68.
3. Wynne-Davies R. Genetic aspects of idiopathic scoliosis. Dev Med Child Neurol 1973;15:809-11.
4. Ogilvie JW, Braun J, Argyle V, et al. The search for idiopathic scoliosis genes. Spine 2006;31:679-51.
5. Miller NH. Genetics of familial idiopathic scoliosis. Clin Orthop Relat Res 2007;462:6-10.
6. Alden KJ, Marosy B, Nzegwu N, et al. Idiopathic scoliosis: identification of candidate regions on chromosome 19p13. Spine 2006;31:1815-19.
7. Miller NH, Justice CM, Marosy B, et al. Identification of candidate regions for familial idiopathic scoliosis. Spine 2005;30:1181-7.
8. Justice CM, Miller NH, Marosy B, et al. Familial idiopathic scoliosis: evidence of an X-linked susceptibility locus. Spine 2003;26:589-94.
9. Chan V, Fong GC, Luk KD, et al. A genetic locus for adolescent idiopathic scoliosis linked to chromosome 19p13.3. Am J Hum Genet 2002;71:401-6.
10. Wise CA, Barnes R, Gillum J, et al. Localization of susceptibility to familial idiopathic scoliosis. Spine 2000;25:2372-80.
11. Miller NH, Marosy B, Justice CM, et al. Linkage analysis of genetic loci for kyphoscoliosis on chromosomes 5p13, 13q13.3, and 13q32. Am J Med Genet A 2006;140:1059-68.
12. Salehi LB, Mangino M, De Serio S. et al. Assignment of a locus for autosomal dominant idiopathic scoliosis (IS) to human chromosome 17p11. Hum Genet 2002;111:401-4.
13. Ajami K, Abbott CA, McCaughan GW, et al. Dipeptidyl peptidase 9 has two forms, a broad tissue distribution, cytoplasmic localization and DPFV-like peptidase activity. Biochim Biophys Acta 2004;1879:18-28.
14. Cheng JC, Qin L, Cheung CS, et al. Generalized low areal and volumetric bone mineral density in adolescent idiopathic scoliosis. J Bone Miner Res 2000;15:1587-95.
15. Cheng JC, Guo X. Osteopenia in adolescent idiopathic scoliosis. A primary problem or secondary to the spinal deformity? Spine 1997;22:1716-21.
16. Siu King Cheung C, Tak Keung Lee W, Kit Tse Y. et al. Abnormal pen-pubertal anthropometric measurements and growth pattern in adolescent idiopathic scoliosis: a study of 598 patients. Spine 2003;26:2152-7.
17. Ylikoski M. Height of girls with adolescent idiopathic scoliosis. Eur Spine J 2003;12:288-91.
18. Ford DM, Bagnall KM, McFadden KD, et al. Paraspinal muscle imbalance in adolescent idiopathic scoliosis. Spine 1984;9:373-6.
19. Ford DM, Bagnall KM. Clements CA. et al. Muscle spindles in the paraspinal musculature of patients with adolescent idiopathic scoliosis. Spine 1988;13:461-5.
20. Benli IT, Uzumcugil O. Aydin E, et al. Magnetic resonance imaging abnormalities of neural axis in Lenke type 1 idiopathic scoliosis. Spine 2006;31:1828-33.
21. Inoue M, Nakata Y, Minami S, et al. idiopathic scoliosis as a presenting sign of familial neurologic abnormalities. Spine 2003;28:40-5.
22. Chu WC, Lam WW, Chan YL, et al. Relative shortening and functional tethering of spinal cord in adolescent idiopathic scoliosis? Study with multiplanar reformat magnetic resonance imaging and somatosensory evoked potential. Spine 2006:31:E19-25.
23. Mirovsky Y, Blankstein A, Shlamkovitch N. Postural control in patients with severe idiopathic scoliosis: a prospective study. J Pediatr Orthop B 2006;15:168-71.
24. Cobb JR. Outline for the study of scoliosis. Instr Course Lect 1948;5:261-75.
25. The International HapMap Consorbtium. The International HapMap Project. Nature 2003;426:789-96.
26. Risch NJ. Searching for genetic determinants in the new millennium. Nature 2000;405:847-56.
27. Cheng JC, Tang NL, Yeung HY, et al. Genetic association of complex traits: using idiopathic scoliosis as an example. Clin Orthop Relat Res 2007;462:38-44.
28. Tang NL, Yeung HY, Lee KM, et al. A relook into the association of the estrogen receptor [alpha] gene (Pvull, Xbal) and adolescent idiopathic scoliosis: a study of 540 Chinese cases. Spine 2006;31:2463-8.
29. Wu J, Qiu Y, Zhang L, et al. Association of estrogen receptor gene polymorphisms with susceptibility to adolescent idiopathic scoliosis. Spine 2006;31:1131-6.
30. Inoue M, Minami S, Nakata Y, et al. Association between estrogen receptor gene polymorphisms and curve severity of idiopathic scoliosis. Spine 2002;27:2357-62.
31. Qiu XS, Tang NL, Yeung HY, et al. Genetic association study of growth hormone receptor and idiopathic scoliosis. Clin Orthop Relat Res 2007;462:53-8.
32. Morcuende JA, Minhas R, Dolan L, et al. Allelic variants of human melatonin 1A receptor in patients with familial adolescent idiopathic scoliosis. Spine 2003;28:2025-8[discussion 2029],
33. Qiu XS, Tang NL, Yeung HY, et al. Melatonin receptor 1B (MTNR1B) gene polymorphism is associated with the occurrence of adolescent idiopathic scoliosis. Spine 2007;32:1748-53.
34. Montanaro L, Parisini P, Greggi T, et al. Evidence of a linkage between matrilin-1 gene (MATN1) and idiopathic scoliosis. Scoliosis 2006;1:21.