Dynamic Contrast-enhanced CT of Head and Neck Tumors. Comparison of First-pass and Permeability Perfusion Measurements Using Two Different Commercially Available Tracer Kinetics Models

Academic Radiology

Volumn 15, Issue 12, 2008, Pages 1580-1589

  Bisdas, Sotirios ^a   Konstantinou, Giorgos ^b   Surlan Popovic, Katarina ^c   Khoshneviszadeh, Arjang ^a   Baghi, Mehran ^e   Vogl, Thomas J ^a   Koh, Tong San ^d   Mack, Martin G ^a  

^a UNIVERSITY HOSPITAL FRANKFURT   (Germany)

^b 401 GENERAL MILITARY HOSPITAL OF ATHENS   (Greece)

^c UNIVERSITY MEDICAL CENTRE LJUBLJANA   (Slovenia)

^d NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

^e NONE

Author keywords

deconvolution based analysis; distributed parameter analysis; Head and neck cancer; maximum slope model; Patlak analysis; perfusion CT

Indexed keywords

ADULT; AGED; ARTICLE; BLOOD FLOW; BLOOD VOLUME; COMPUTER ASSISTED TOMOGRAPHY; COMPUTER PROGRAM; CONTRAST ENHANCEMENT; CONTROLLED STUDY; FEMALE; HEAD AND NECK TUMOR; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RANK SUM TEST;

ADULT; ALGORITHMS; COMPUTER SIMULATION; CONTRAST MEDIA; FEMALE; HEAD AND NECK NEOPLASMS; HUMANS; KINETICS; MALE; METABOLIC CLEARANCE RATE; MODELS, BIOLOGICAL; PERFUSION; PERMEABILITY; RADIOGRAPHIC IMAGE ENHANCEMENT; RADIOGRAPHIC IMAGE INTERPRETATION, COMPUTER-ASSISTED; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TOMOGRAPHY, X-RAY COMPUTED;

EID: 55349115101     PISSN: 10766332     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.acra.2008.05.021     Document Type: Article

References (35)

1. Peters A.M., Brown J., Hartnell G.G., Myers M.J., Haskell C., and Lavender J.P. Non-invasive measurement of renal blood flow with 99mTc DTPA: comparison with radiolabelled microspheres. Cardiovasc Res 21 (1987) 830-834
2. Miles K.A. Measurement of tissue perfusion by dynamic computed tomography. Br J Radiol 64 (1991) 409-412
3. Cenic A., Nabavi D.G., Craen R.A., Gelb A.W., and Lee T.Y. Dynamic CT measurement of cerebral blood flow: a validation study. AJNR Am J Neuroradiol 20 (1999) 63-73
4. Bisdas S., Baghi M., Smolarz A., et al. Quantitative measurements of perfusion and permeability of oropharyngeal and oral cavity cancer, recurrent disease, and associated lymph nodes using first-pass contrast-enhanced computed tomography studies. Invest Radiol 42 (2007) 172-179
5. Gandhi D., Hoeffner E.G., Carlos R.C., Case I., and Mukherji S.K. Computed tomography perfusion of squamous cell carcinoma of the upper aerodigestive tract. Initial results. J Comput Assist Tomogr 27 (2003) 687-693
6. Rumboldt Z., Al-Okaili R., and Deveikis J.P. Perfusion CT for head and neck tumors: pilot study. AJNR Am J Neuroradiol 26 (2005) 1178-1185
7. Gamel J., Rousseau W.F., Katholi C.R., and Mesel E. Pitfalls in digital computation of the impulse response of vascular beds from indicator-dilution curves. Circ Res 32 (1973) 516-523
8. Patlak C.S., Blasberg R.G., and Fenstermacher J.D. Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data. J Cereb Blood Flow Metab 3 (1983) 1-7
9. St. Lawrence K.S., and Lee T.Y. An adiabatic approximation to the tissue homogeneity model for water exchange in the brain: I. Theoretical derivation. J Cereb Blood Flow Metab 18 (1998) 1365-1377
10. Goh V., Halligan S., and Bartram C.I. Quantitative tumor perfusion assessment with multidetector CT: are measurements from two commercial software packages interchangeable?. Radiology 242 (2007) 777-782
11. Bland J.M., and Altman D.G. Applying the right statistics: analyses of measurement studies. Ultrasound Obstet Gynecol 22 (2003) 85-93
12. Hermans R., Lambin P., Van den Bogaert W., Haustermans K., Van der Goten A., and Baert A.L. Non-invasive tumour perfusion measurement by dynamic CT: preliminary results. Radiother Oncol 44 (1997) 159-162
13. Gandhi D., Chepeha D.B., Miller T., et al. Correlation between initial and early follow-up CT perfusion parameters with endoscopic tumor response in patients with advanced squamous cell carcinomas of the oropharynx treated with organ-preservation therapy. AJNR Am J Neuroradiol 27 (2006) 101-106
14. Bisdas S., Baghi M., Wagenblast J., et al. Differentiation of benign and malignant parotid tumors using deconvolution-based perfusion CT imaging: feasibility of the method and initial results. Eur J Radiol 64 (2007) 258-265
15. Hermans R., Lambin P., Van der Goten A., et al. Tumoural perfusion as measured by dynamic computed tomography in head and neck carcinoma. Radiother Oncol 53 (1999) 105-111
16. Hermans R., Meijerink M., Van den Bogaert W., Rijnders A., Weltens C., and Lambin P. Tumor perfusion rate determined noninvasively by dynamic computed tomography predicts outcome in head-and-neck cancer after radiotherapy. Int J Radiat Oncol Biol Phys 57 (2003) 1351-1356
17. Miles K.A., and Griffiths M.R. Perfusion CT: a worthwhile enhancement?. Br J Radiol 76 (2003) 220-231
18. Hu C.H., Wu Q.D., Hu X.Y., Fang X.M., Zhang T.H., and Ding Y. Hemodynamic studies on brain CT perfusion imaging with varied injection rates. Clin Imaging 31 (2007) 151-154
19. Blomley M.J., Coulden R., Bufkin C., Lipton M.J., and Dawson P. Contrast bolus dynamic computed tomography for the measurement of solid organ perfusion. Invest Radiol 28 suppl (1993) S72-S77
20. Koenig M., Klotz E., Luka B., Venderink D.J., Spittler J.F., and Heuser L. Perfusion CT of the brain: diagnostic approach for early detection of ischemic stroke. Radiology 209 (1998) 85-93
21. Kiessling F., Boese J., Corvinus C., et al. Perfusion CT in patients with advanced bronchial carcinomas: a novel chance for characterization and treatment monitoring?. Eur Radiol 14 (2004) 1226-1233
22. Miles K.A. Perfusion CT for the assessment of tumour vascularity: which protocol?. Br J Radiol 76 (2003) S36-S42
23. Daldrup-Link H.E., Rydland J., Helbich T.H., et al. Quantification of breast tumor microvascular permeability with feruglose-enhanced MR imaging: initial phase II multicenter trial. Radiology 229 (2003) 885-892
24. Goh V., Halligan S., Hugill J.A., Gartner L., and Bartram C.I. Quantitative colorectal cancer perfusion measurement using dynamic contrast-enhanced multidetector-row computed tomography: effect of acquisition time and implications for protocols. J Comput Assist Tomogr 29 (2005) 59-63
25. Axel L. Cerebral blood flow determination by rapid-sequence computed tomography: theoretical analysis. Radiology 137 (1980) 679-686
26. Meier P., and Zierler K.L. On the theory of the indicator-dilution method for measurement of blood flow and volume. J Appl Physiol 6 (1954) 731-744
27. Ostergaard L., Weisskoff R.M., Chesler D.A., Gyldensted C., and Rosen B.R. High resolution measurement of cerebral blood flow using intravascular tracer bolus passages. Part I: Mathematical approach and statistical analysis. Magn Reson Med 36 (1996) 715-725
28. Ostergaard L., Sorensen A.G., Kwong K.K., Weisskoff R.M., Gyldensted C., and Rosen B.R. High resolution measurement of cerebral blood flow using intravascular tracer bolus passages. Part II: experimental comparison and preliminary results. Magn Reson Med 36 (1996) 726-736
29. Bisdas S., Donnerstag F., Ahl B., Bohrer I., Weissenborn K., and Becker H. Comparison of perfusion computed tomography with diffusion-weighted magnetic resonance imaging in hyperacute ischemic stroke. J Comput Assist Tomogr 28 (2004) 747-755
30. Eastwood J.D., Lev M.H., Wintermark M., et al. Correlation of early dynamic CT perfusion imaging with whole-brain MR diffusion and perfusion imaging in acute hemispheric stroke. AJNR Am J Neuroradiol 24 (2003) 1869-1875
31. Wintermark M., Reichhart M., Thiran J.P., et al. Prognostic accuracy of cerebral blood flow measurement by perfusion computed tomography, at the time of emergency room admission, in acute stroke patients. Ann Neurol 51 (2002) 417-432
32. Johnson J.A., and Wilson T.A. A model for capillary exchange. Am J Physiol 210 (1966) 1299-1303
33. Larson K.B., Markham J., and Raichle M.E. Tracer-kinetic models for measuring cerebral blood flow using externally detected radiotracers. J Cereb Blood Flow Metab 7 (1987) 443-463
34. Peters A.M., Gunasekera R.D., Henderson B.L., et al. Noninvasive measurement of blood flow and extraction fraction. Nucl Med Commun 8 (1987) 823-837
35. Konig M., Klotz E., and Heuser L. Cerebral perfusion CT: theoretical aspects, methodical implementation and clinical experience in the diagnosis of ischemic cerebral infarction. Rofo 172 (2000) 210-218