A new dinuclear platinum complex with a nitrogen-containing geminal bisphosphonate as potential anticancer compound specifically targeted to bone tissues

Journal of Inorganic Biochemistry

Volumn 102, Issue 12, 2008, Pages 2078-2086

  Margiotta, Nicola ^a   Capitelli, Francesco ^b   Ostuni, Rosa ^a   Natile, Giovanni ^a  

^a UNIVERSITY OF BARI   (Italy)

^b CNR   (Italy)

Author keywords

Bone tumors; Geminal bisphosphonates; NMR spectroscopy; Platinum complexes; Sol gel crystallization; X ray diffraction

Indexed keywords

BISPHOSPHONIC ACID DERIVATIVE; NITROGEN; PLATINUM COMPLEX; RISEDRONIC ACID;

ARTICLE; BONE TISSUE; BONE TUMOR; CRYSTALLIZATION; DRUG CONFORMATION; DRUG STRUCTURE; DRUG SYNTHESIS; HYDROGEN BOND; METASTASIS; PH MEASUREMENT; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PROTON NUCLEAR MAGNETIC RESONANCE; X RAY DIFFRACTION;

ANTINEOPLASTIC AGENTS; BONE DENSITY CONSERVATION AGENTS; BONE NEOPLASMS; CELL LINE, TUMOR; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; DIPHOSPHONATES; ETIDRONIC ACID; HUMANS; ORGANOPLATINUM COMPOUNDS;

EID: 55349108493     PISSN: 01620134     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jinorgbio.2008.07.008     Document Type: Article

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