Low glycemic index treatment: Implementation and new insights into efficacy

Epilepsia

Volumn 49, Issue SUPPL. 8, 2008, Pages 42-45

  Pfeifer, Heidi H ^a   Lyczkowski, David A ^a   Thiele, Elizabeth A ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Dietary therapy; Glycemic index; Low glycemic index treatment; Refractory epilepsy

Indexed keywords

ANTICONVULSIVE AGENT; GLUCOSE;

CONFERENCE PAPER; DIET THERAPY; EPILEPSY; GLUCOSE BLOOD LEVEL; GLUCOSE INTAKE; GLYCEMIC INDEX; KETOGENIC DIET; PRIORITY JOURNAL; SEIZURE;

DIET THERAPY; EPILEPSY; GLYCEMIC INDEX; HUMANS;

EID: 55349104803     PISSN: 00139580     EISSN: 15281167     Source Type: Journal    
DOI: 10.1111/j.1528-1167.2008.01832.x     Document Type: Conference Paper

References (20)

1. Appleton DB, DeVivo DC 1974) An animal model for the ketogenic diet. Epilepsia 15 : 211 227.
2. Bailey EE, Pfeifer HH, Thiele EA 2005) The use of diet in the treatment of epilepsy. Epilepsy Behav 6 : 6 8.
3. Bell SJ, Sears B 2003) Low-glycemic-load diets: impact on obesity and chronic diseases [Abstract]. Crit Rev Food Sci Nutr 43 : 357 377.
4. Bough KJ, Chen RS, Eagles DA 1999) Path analysis shows that increasing ketogenic ratio, but not beta-hydroxybutyrate, elevates seizure threshold in the rat. Dev Neurosci 21 : 400 406.
5. Brand J, Colagiuri S, Crossman S, Allen A, Roberts D, Truswell A 1991) Low glycemic index foods improve long-term glycemic control in NIDDM. Diabetes 14 : 95 101.
6. Brynes AE, Adamson J, Dornhorst A, Frost GS 2005) The beneficial effect of a diet with low glycaemic index on 24 h glucose profiles in healthy young people as assessed by continuous glucose monitoring [Abstract]. Br J Nutr 93 : 179 182.
7. DeVivo DC, Leckie MP, Ferrendelli JS, McDougal DB Jr. 1978) Chronic ketosis and cerebral metabolism. Ann Neurol 3 : 331 337.
8. Greene AE, Todorova MT, McGowan R, Seyfried TN 2001) Caloric restriction inhibits seizure susceptibility in epileptic EL mice by reducing blood glucose. Epilepsia 42 : 1371 1378.
9. Greene AE, Todorova MT, Seyfried TN 2003) Perspectives on the metabolic management of epilepsy through dietary reduction of glucose and elevation of ketone bodies. J Neurochem 86 : 529 537.
10. Haymond MW, Howard C, Ben-Galim E, DeVivo DC 1983) Effects of ketosis on glucose flux in children and adults. Am J Physiol 245 : E373 E378.
11. Huttenlocher PR. (1976) Ketonemia and seizures: metabolic and anticonvulsant effects of two ketogenic diets in childhood epilepsy. Pediatr Res 10 : 536 540.
12. Jenkins DJ, Wolever TM, Taylor RH, Barker H, Fielden H, Baldwin JM, Bowling AC, Newman HC, Jenkins AL, Goff DV 1981) Glycemic index of foods: a physiological basis for carbohydrate exchange. Am J Clin Nutr 34 : 362 366.
13. Kossoff EH, McGrogan JR, Bluml RM, Pillas DJ, Rubenstien JE, Vining EP 2006) A modified Atkins diet is effective for the treatment of intractable pediatric epilepsy. Epilepsia 47 : 421 424.
14. Owen OE, Morgan AP, Kemp HG, Sullivan JM, Herrera, Cahill GF Jr. 1967) Brain metabolism during fasting. J Clin Invest 46 : 1589 1595.
15. Pfeifer HH, Thiele EA 2005) Low glycemic index treatment: a liberalized ketogenic diet for treatment of intractable epilepsy. Neurology 65 : 1810 1812.
16. Rizkalla SW, Taghrid L, Laromiguiere M, Huet D, Boillot J, Rigoir A, Elgrably F, Slama G 2004) Improved plasma glucose control, whole-body glucose utilization, and lipid profile on a low-glycemic index diet in type 2 diabetic men. Diabetes Care 27 : 1866 1872.
17. Schwartzkroin PA. (1999) Mechanisms underlying the anti-epileptic efficacy of the ketogenic diet. Epilepsy Res 37 : 171 180.
18. Schwechter EM, Veliskova J, Velisek L 2003) Correlation between extracellular glucose and seizure susceptibility in adult rats. Ann Neurol 53 : 91 101.
19. Thio LL, Wong M, Yamada KA 2000) Ketone bodies do not directly alter excitatory or inhibitory hippocampal synaptic transmission. Neurology 54 : 325 331.
20. Valencia I, Pfeifer H, Thiele EA 2002) General anesthesia and the ketogenic diet: clinical experience in nine patients. Epilepsia 43 : 525 529.