The effect of Fenton reaction on protease-resistant prion protein (PrP Sc) degradation and scrapie infectivity

Brain Research

Volumn 1238, Issue , 2008, Pages 172-180

  Park, Seok Joo ^a   Kim, Nam Ho ^a   Jeong, Byung Hoon ^a   Jin, Jae Kwang ^a   Choi, Jin Kyu ^a   Park, Young Jae ^a   Kim, Jae Il ^b   Carp, Richard I ^b   Kim, Yong Sun ^a  

^a Hallym University   (South Korea)

^b NEW YORK STATE INSTITUTE FOR BASIC RESEARCH IN DEVELOPMENTAL DISABILITIES   (United States)

Author keywords

Fenton reaction; Hydroxylation; Metal catalyzed oxidation (MCO); Oxygen free radical; Prion diseases; Prion protein degradation

Indexed keywords

FERROUS ION; MANGANESE; PRION PROTEIN; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN HOMOGENATE; CONTROLLED STUDY; FENTON REACTION; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEGRADATION; SCRAPIE; SYRIAN HAMSTER; VIRUS INFECTIVITY;

ANIMALS; BLOTTING, WESTERN; BRAIN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CRICETINAE; HYDROGEN PEROXIDE; IMMUNOHISTOCHEMISTRY; IRON; MALE; MESOCRICETUS; OXIDATIVE STRESS; PRPSC PROTEINS; SCRAPIE; THIOBARBITURIC ACID REACTIVE SUBSTANCES;

EID: 55349097460     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2008.07.117     Document Type: Article

References (27)

1. Basu S., Mohan M.L., Luo X., Kundu B., Kong Q., and Singh N. Modulation of proteinase K-resistant prion protein in cells and infectious brain homogenate by redox iron: implications for prion replication and disease pathogenesis Mol. Biol. Cell 18 2007 3302 3312
2. Berlett B.S., and Stadtman E.R. Protein oxidation in aging, disease, and oxidative stress J. Biol. Chem. 272 1997 20313 20316
3. Bolton D.C., McKinley M.P., and Prusiner S.B. Identification of a protein that purifies with the scrapie prion Science 218 1982 1309 1311
4. Castellani R.J., Perry G., and Smith M.A. Prion disease and Alzheimer's disease: pathogenic overlap Acta Neurobiol. Exp. (Wars) 64 2004 11 17
5. Choi Y.G., Kim J.I., Jeon Y.C., Park S.J., Choi E.K., Rubenstein R., Kascsak R.J., Carp R.I., and Kim Y.S. Nonenzymatic glycation at the N terminus of pathogenic prion protein in transmissible spongiform encephalopathies J. Biol. Chem. 279 2004 30402 30409
6. Davies P., and Brown D.R. The chemistry of copper binding to PrP: is there sufficient evidence to elucidate a role for copper in protein function? Biochem. J. 410 2008 237 244
7. Dean R.T., Fu S., Stocker R., and Davies M.J. Biochemistry and pathology of radical-mediated protein oxidation Biochem. J. 324 1997 1 18
8. Giese A., Levin J., Bertsch U., and Kretzschmar H. Effect of metal ions on de novo aggregation of full-length prion protein Biochem. Biophys. Res. Commun. 320 2004 1240 1246
9. Guentchev M., Siedlak S.L., Jarius C., Tagliavini F., Castellani R.J., Perry G., Smith M.A., and Budka H. Oxidative damage to nucleic acids in human prion disease Neurobiol. Dis. 9 2002 275 281
10. Halliwell B. Reactive oxygen species and the central nervous system J. Neurochem. 59 1992 1609 1623
11. Kim N.H., Park S.J., Jin J.K., Kwon M.S., Choi E.K., Carp R.I., and Kim Y.S. Increased ferric iron content and iron-induced oxidative stress in the brains of scrapie-infected mice Brain Res. 884 2000 98 103
12. res FASEB J. 19 2005 783 785
13. Lee K.H., Jeong B.H., Jin J.K., Meeker H.C., Kim J.I., Carp R.I., and Kim Y.S. Scrapie infection activates the replication of ecotropic, xenotropic, and polytropic murine leukemia virus (MuLV) in brains and spinal cords of senescence-accelerated mice: implication of MuLV in progression of scrapie pathogenesis Biochem. Biophys. Res. Commun. 349 2006 122 130
14. Lehmann S. Metal ions and prion diseases Curr. Opin. Chem. Biol. 6 2002 187 192
15. Milhavet O., McMahon H.E., Rachidi W., Nishida N., Katamine S., Mangé A., Arlotto M., Casanova D., Riondel J., Favier A., and Lehmann S. Prion infection impairs the cellular response to oxidative stress Proc. Natl. Acad. Sci. USA 97 2000 13937 13942
16. Ohkawa H., Ohishi N., and Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction Anal. Biochem. 95 1979 351 358
17. Petersen R.B., Siedlak S.L., Lee H.G., Kim Y.S., Nunomura A., Tagliavini F., Ghetti B., Cras P., Moreira P.I., Castellani R.J., Guentchev M., Budka H., Ironside J.W., Gambetti P., Smith M.A., and Perry G. Redox metals and oxidative abnormalities in human prion diseases Acta Neuropathol. 110 2005 232 238
18. Quaglio E., Chiesa R., and Harris D.A. Copper converts the cellular prion protein into a protease-resistant species that is distinct from the scrapie isoform J. Biol. Chem. 276 2001 11432 11438
19. Requena J.R., Groth D., Legname G., Stadtman E.R., Prusiner S.B., and Levine R.L. Copper-catalyzed oxidation of the recombinant SHa (29-231) prion protein Proc. Natl. Acad. Sci. USA 98 2001 7170 7175
20. Sayre L.M., Perry G., and Smith M.A. Redox metals and neurodegenerative disease Curr. Opin. Chem. Biol. 3 1999 220 225
21. Stadtman E.R., and Berlett B.S. Reactive oxygen-mediated protein oxidation in aging and disease Drug Metab. Rev. 30 1998 225 243
22. Stadtman E.R., and Levine R.L. Free radical-mediated oxidation of free amino acids and amino acid residues in proteins Amino Acids 25 2003 207 218
23. Suyama K., Yoshioka M., Akagawa M., Murayama Y., Horii H., Takata M., Yokoyama T., and Mohri S. Assessment of prion inactivation by fenton reaction using protein misfolding cyclic amplification and bioassay Biosci. Biotechnol. Biochem. 71 2007 2069 2071
24. Tsenkova R.N., Iordanova I.K., Toyoda K., and Brown D.R. Prion protein fate governed by metal binding Biochem. Biophys. Res. Commun. 325 2004 1005 1012
25. Wadsworth J.D., Hill A.F., Joiner S., Jackson G.S., Clarke A.R., and Collinge J. Strain-specific prion-protein conformation determined by metal ions Nat. Cell Biol. 1 1999 55 59
26. Wong B.S., Pan T., Liu T., Li R., Petersen R.B., Jones I.M., Gambetti P., Brown D.R., and Sy M.S. Prion disease: a loss of antioxidant function? Biochem. Biophys. Res. Commun. 275 2000 249 252
27. Zhu X., Su B., Wang X., Smith M.A., and Perry G. Causes of oxidative stress in Alzheimer disease Cell. Mol. Life Sci. 64 2007 2202 2210