Co-selection of West Nile virus nucleotides that confer resistance to an antisense oligomer while maintaining long-distance RNA/RNA base pairings

Virology

Volumn 382, Issue 1, 2008, Pages 98-106

  Zhang, Bo ^a   Dong, Hongping ^a   Stein, David A ^b   Shi, Pei Yong ^a,c  

^a WADSWORTH CENTER   (United States)

^b AVI BIOPHARMA INC   (United States)

^c STATE UNIVERSITY OF NEW YORK   (United States)

Author keywords

Antiviral therapy; Flavivirus replication; Genome cyclization; RNA cis elements; West Nile virus

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; NUCLEOTIDE; VIRUS RNA;

3' UNTRANSLATED REGION; 5' UNTRANSLATED REGION; ANIMAL CELL; ARTICLE; BASE MISPAIRING; BASE PAIRING; CONTROLLED STUDY; MOLECULAR INTERACTION; MUTAGENESIS; MUTATIONAL ANALYSIS; NONHUMAN; PRIORITY JOURNAL; RNA BINDING; RNA SEQUENCE; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; VIRUS MUTATION; VIRUS PLAQUE; WEST NILE FLAVIVIRUS;

ADAPTATION, BIOLOGICAL; ANTIVIRAL AGENTS; BASE PAIRING; BASE SEQUENCE; DRUG RESISTANCE, VIRAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; OLIGONUCLEOTIDES, ANTISENSE; PLAQUE ASSAY; POINT MUTATION; SELECTION (GENETICS); WEST NILE VIRUS;

FLAVIVIRUS; WEST NILE VIRUS;

EID: 55249122870     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2008.08.044     Document Type: Article

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