Par-1 and PP2A Yin-Yang of Bazooka localization

Fly

Volumn 1, Issue 4, 2007, Pages 235-237

  Choi, Kwang Wook ^a   Nam, Sang Chul ^b   Mukhopadhyay, Bibhash ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b BAYLOR UNIVERSITY   (United States)

Author keywords

Apical basal; Bazooka; Cell polarity; Drosophila eye; Morphogenesis; Par 1; Photoreceptor; Protein phosphatase 2a

Indexed keywords

BAZOOKA PROTEIN, DROSOPHILA; DROSOPHILA PROTEIN; PAR 1 PROTEIN, DROSOPHILA; PAR-1 PROTEIN, DROSOPHILA; PHOSPHOPROTEIN PHOSPHATASE; PROTEIN SERINE THREONINE KINASE; SIGNAL PEPTIDE;

ANIMAL; ARTICLE; CELL POLARITY; DROSOPHILA; EYE; METABOLISM; PHOSPHORYLATION; PHOTORECEPTOR; PRENATAL DEVELOPMENT;

ANIMALS; CELL POLARITY; DROSOPHILA; DROSOPHILA PROTEINS; EYE; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; PHOSPHOPROTEIN PHOSPHATASES; PHOSPHORYLATION; PHOTORECEPTORS, INVERTEBRATE; PROTEIN-SERINE-THREONINE KINASES;

EID: 55249116850     PISSN: 19336934     EISSN: 19336942     Source Type: Journal    
DOI: 10.4161/fly.4954     Document Type: Article

References (16)

1. Longley Jr RL, Ready DF. Integrins and the development of three-dimensional structure in the Drosophila compound eye. Dev Biol 1995; 171:415-33.
2. Benton R, St Johnston D. Drosophila P-AR-1 and 14-3-3 inhibit Bazooka/PAR-3 to estab-lish complementary cortical domains in polarized cells. Cell 2003; 115:691-704.
3. Nam SC, Mukhopadhyay B, Choi KW. Antagonistic functions of Par-1 kinase and protein phosphatase 2A are required for localization of Bazooka and photoreceptor morphogenesis in Drosophila. Dev Biol 2007; 306:624-35.
4. Bayraktar J, Zygmunt D, Carthew RW. Par-1 kinase establishes cell polarity and functions in Notch signaling in the Drosophila embryo. J Cell Sci 2006; 119:711-21.
5. Pellikka M, Tanentzapf G, Pinto M, Smith C, McGlade CJ, Ready DF, Tepass U. Crumbs, the Drosophila homologue of human CRB1/RP12, is essential for photoreceptor morpho-genesis. Nature 2002; 416:143-9.
6. Izaddoost S, Nam SC, Bhat MA, Bellen HJ, Choi KW. Drosophila Crumbs is a positional cue in photoreceptor adherens junctions and rhabdomeres. Nature 2002; 416:178-83.
7. Johnson K, Grawe F, Grzeschik N, Knust E. Drosophila crumbs is required to inhibit light-induced photoreceptor degeneration. Curr Biol 2002; 12:1675-80.
8. den Hollander AI, Heckenlively JR, van den Born LI, de Kok YJ, van der Velde-Visser SD, Kellner U, Jurklies B, van Schooneveld MJ, Blankenagel A, Rohrschneider K, Wissinger B, Cruysberg JR, Deutman AF, Brunner HG, Apfelstedt-Sylla E, Hoyng CB, Cremers FP. Leber congenital amaurosis and retinitis pigmentosa with Coats-like exudative vasculopathy are associated with mutations in the crumbs homologue 1 (CRB1) gene. Am J Hum Genet 2001; 69:198-203.
9. den Hollander AI, ten Brink JB, de Kok YJ, van Soest S, van den Born LI, van Driel MA, van de Pol DJ, Payne AM, Bhattacharya SS, Kellner U, Hoyng CB, Westerveld A, Brunner HG, Bleeker-Wagemakers EM, Deutman AF, Heckenlively JR, Cremers FP, Bergen AA. Mutations in a human homologue of Drosophila crumbs cause retinitis pigmentosa (RP12). Nat Genet 1999; 23:217-21.
10. Hannus M, Feiguin F, Heisenberg CP, Eaton S. Planar cell polarization requires Widerborst, a B' regulatory subunit of protein phosphatase 2A. Development 2002; 129:3493-503.
11. Bajpai R, Makhijani K, Rao PR, Shashidhara LS. Drosophila Twins regulates Armadillo levels in response to Wg/Wnt signal. Development 2004; 131:1007-16.
12. Uemura T, Shiomi K, Togashi S, Takeichi M. Mutation of twins encoding a regulator of protein phosphatase 2A leads to pattern duplication in Drosophila imaginal discs. Genes Dev 1993; 7:429-40.
13. Nam SC, Choi KW. Interaction of Par-6 and Crumbs complexes is essential for photorecep-tor morphogenesis in Drosophila. Development 2003; 130:4363-72.
14. Hong Y, Ackerman L, Jan LY, Jan YN. Distinct roles of Bazooka and Stardust in the specifi-cation of Drosophila photoreceptor membrane architecture. Proc Natl Acad Sci USA 2003; 100:12712-7.
15. Gao M, Karin M. Regulating the regulators: Control of protein ubiquitination and ubiqui-tin-like modifications by extracellular stimuli. Mol Cell 2005; 19:581-93.
16. Sathyanarayanan S, Zheng X, Xiao R, Sehgal A. Posttranslational regulation of Drosophila PERIOD protein by protein phosphatase 2A. Cell 2004; 116:603-15.