Pulmonary diffusing capacity for nitric oxide during exercise in morbid obesity

Obesity

Volumn 16, Issue 11, 2008, Pages 2431-2438

  Zavorsky, Gerald S ^a   Kim, Do J ^a   McGregor, Elspeth R ^a   Starling, Jennifer M ^a   Gavard, Jeffrey A ^a  

^a SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON MONOXIDE; NITRIC OXIDE;

ADULT; ARTICLE; BLOOD; CASE CONTROL STUDY; EXERCISE; FEMALE; HEART RATE; HUMAN; LUNG ALVEOLUS; LUNG DIFFUSION CAPACITY; LUNG GAS EXCHANGE; MALE; METABOLISM; MIDDLE AGED; MORBID OBESITY; OXYGEN CONSUMPTION; PATHOPHYSIOLOGY; PHYSIOLOGY;

ADULT; BLOOD-AIR BARRIER; CARBON MONOXIDE; CASE-CONTROL STUDIES; EXERCISE; FEMALE; HEART RATE; HUMANS; MALE; MIDDLE AGED; NITRIC OXIDE; OBESITY, MORBID; OXYGEN CONSUMPTION; PULMONARY ALVEOLI; PULMONARY DIFFUSING CAPACITY;

EID: 55249097123     PISSN: 19307381     EISSN: 1930739X     Source Type: Journal    
DOI: 10.1038/oby.2008.402     Document Type: Article

References (43)

1. Meyer M, Piiper J. Nitric oxide (NO), a new test gas for study of alveolar-capillary diffusion. Eur Respir J 1989;2:494-496.
2. van der Lee I, Zanen P, Biesma DH, van den Bosch JM. The effect of red cell transfusion on nitric oxide diffusing capacity. Respiration 2005;72:512-516.
3. Johnson RL Jr, Heigenhauser GJF, Hsia CCW, Jones NL, Wagner PD. Determinants of gas exchange and acid-balance during exercise. In: Rowell LB, Shepard JT (eds). Handbook of Physiology. Section 12: Exercise: Regulation and Integration of Multiple Systems. Oxford University Press: New York, 1996, pp 515-584.
4. Tamhane RM, Johnson RL Jr, Hsia CC. Pulmonary membrane diffusing capacity and capillary blood volume measured during exercise from nitric oxide uptake. Chest 2001;120:1850-1856.
5. Phansalkar AR, Hanson CM, Shakir AR, Johnson RL Jr, Hsia CC. Nitric oxide diffusing capacity and alveolar microvascular recruitment in sarcoidosis. Am J Respir Crit Care Med 2004;169:1034-1040.
6. Zavorsky GS, Murias JM. A small amount of inhaled nitric oxide does not increase lung diffusing capacity. Eur Respir J 2006;27:1251-1257.
7. Moinard J, Guenard H. Determination of lung capillary blood volume and membrane diffusing capacity in patients with COLD using the NO-CO method. Eur Respir J 1990;3:318-322.
8. van der Lee I, Zanen P, Grutters JC, Snijder RJ, van den Bosch JM. Diffusing capacity for nitric oxide and carbon monoxide in patients with diffuse parenchymal lung disease and pulmonary arterial hypertension. Chest 2006;129:378-383.
9. Borland C, Cox Y, Higenbottam T. Reduction of pulmonary capillary blood volume in patients with severe unexplained pulmonary hypertension. Thorax 1996;51:855-856.
10. Moinard J, Guenard H. Membrane diffusion of the lungs in patients with chronic renal failure. Eur Respir J 1993;6:225-230.
11. Glénet SN, De Bisschop C, Vargas F, Guénard HJ. Deciphering the nitric oxide to carbon monoxide lung transfer ratio: physiological implications. J Physiol 2007;582:767-775.
12. Ogden CL, Carroll MD, Curtin LR et al. Prevalence of overweight and obesity in the United States, 1999-2004. JAMA 2006;295:1549-1555.
13. Flegal KM, Carroll MD, Ogden CL, Johnson CL. Prevalence and trends in obesity among US adults, 1999-2000. JAMA 2002;288:1723-1727.
14. Zavorsky GS, Kim DJ, Sylvestre JL, Christou NV. Alveolar-membrane diffusing capacity improves in the morbidly obese after bariatric surgery. Obes Surg 2008;18:256-263.
15. Zavorsky GS, Christou NV, Kim DJ, Carli F, Mayo NE. Preoperative gender differences in pulmonary gas exchange in morbidly obese subjects. Obesity Surg 2008; e-pub ahead of print 9 May 2008 (doi:10.1007/s11695-008-9527-6).
16. Sartorio A, Malavolti M, Agosti F et al. Body water distribution in severe obesity and its assessment from eight-polar bioelectrical impedance analysis. Eur J Clin Nutr 2005;59:155-160.
17. Deitel M, Greenstein RJ. Recommendations for reporting weight loss. Obes Surg 2003;13:159-160.
18. Jones NL, Makrides L, Hitchcock C, Chypchar T, McCartney N. Normal standards for an incremental progressive cycle ergometer test. Am Rev Respir Dis 1985;131:700-708.
19. Hankinson JL, Odencrantz JR, Fedan KB. Spirometric reference values from a sample of the general U.S. population. Am J Respir Crit Care Med 1999;159:179-187.
20. Macintyre N, Crapo RO, Viegi G et al. Standardisation of the single-breath determination of carbon monoxide uptake in the lung. Eur Respir J 2005;26:720-735.
21. Jones RS, Meade F. A theoretical and experimental analysis of anomalies in the estimation of pulmonary diffusing capacity by the single breath method. Q J Exp Physiol 1961;46:131-143.
22. Roughton FJW, Forster RE. Relative importance of diffusion and chemical reaction rates in determining rate of exchange of gases in the human lung, with special reference to true diffusing capacity of pulmonary membrane and volume of blood in the lung capillaries. J Appl Physiol 1957;11:290-302.
23. Zavorsky GS, Cao J, Murias JM. Reference values of pulmonary diffusing capacity for nitric oxide in an adult population. Nitric Oxide 2008;18:70-79.
24. Zavorsky GS, Quiron KB, Massarelli PS, Lands LC. The relationship between single-breath diffusion capacity of the lung for nitric oxide and carbon monoxide during various exercise intensities. Chest 2004;125:1019-1027.
25. Borland CD, Higenbottam TW. A simultaneous single breath measurement of pulmonary diffusing capacity with nitric oxide and carbon monoxide. Eur Respir J 1989;2:56-63.
26. Sugerman H, Windsor A, Bessos M, Wolfe L. Intra-abdominal pressure, sagittal abdominal diameter and obesity comorbidity. J Internal Med 1997;241:71-79.
27. Ofir D, Laveneziana P, Webb KA, O'Donnell D. Ventilatory and perceptual responses to cycle exercise in obese females. J Appl Physiol 2007;102:2217-2226.
28. Snyder EM, Olson TP, Johnson BD, Franz RP. Influence of sildenafil on lung diffusion during exposure to acute hypoxia at rest and during exercise in healthy humans. Eur J Appl Physiol 2008;103:421-430.
29. Borland C. Nitric oxide diffusing capacity on exercise. Chest 2004;126:1708; author reply 1709-1710.
30. Borland CD, Cox Y. Effect of varying alveolar oxygen partial pressure on diffusing capacity for nitric oxide and carbon monoxide, membrane diffusing capacity and lung capillary blood volume. Clin Sci (Lond) 1991;81:759-765.
31. Puri S, Baker BL, Dutka DP et al. Reduced alveolar-capillary membrane diffusing capacity in chronic heart failure. Its pathophysiological relevance and relationship to exercise performance. Circulation 1995;91:2769-2774.
32. Guazzi M, Brambilla R, De Vita S, Guazzi MD. Diabetes worsens pulmonary diffusion in heart failure, and insulin counteracts this effect. A, J Respir Crit Care Med 2002;166:978-982.
33. Bottai M, Pistelli F, Di Pede F et al. Longitudinal changes of body mass index, spirometry and diffusion in a general population. Eur Respir J 2002;20:665-673.
34. Jones RL, Nzekwu MM. The effects of body mass index on lung volumes. Chest 2006;130:827-833.
35. Collard P, Wilputte JY, Aubert G, Rodenstein DO, Frans A. The single-breath diffusing capacity for carbon monoxide in obstructive sleep apnea and obesity. Chest 1996;110:1189-1193.
36. Saydain G, Beck KC, Decker PA, Cowl CT, Scanlon PD. Clinical significance of elevated diffusing capacity. Chest 2004;125:446-452.
37. Oppenheimer BW, Berger KI, Rennert DA et al. Effect of circulatory congestion on the components of pulmonary diffusing capacity in morbid obesity. Obesity (Silver Spring) 2006;14:1172-1180.
38. Ray CS, Sue DY, Bray G, Hansen JE, Wasserman K. Effects of obesity on respiratory function. Am Review Respir Dis 1983;128:501-506.
39. Biring MS, Lewis MI, Liu JT, Mohsenifar Z. Pulmonary physiologic changes of morbid obesity. Am J Med Sci 1999;318:293-297.
40. Zavorsky GS, Murias JM, Kim do J et al. Waist-to-hip ratio is associated with pulmonary gas exchange in the morbidly obese. Chest 2007;131:362-367.
41. Frans A, Nemery B, Veriter C, Lacquet L, Francis C. Effect of alveolar volume on the interpretation of single breath DLCO. Respir Med 1997;91:263-273.
42. Borland C, Mist B, Zammit M, Vuylsteke A. Steady-state measurement of NO and CO lung diffusing capacity on moderate exercise in men. J Appl Physiol 2001;90:538-544.
43. Glénet SN, de Bisschop CM, Dridi R, Guénard HJ. Membrane conductance in trained and untrained subjects using either steady state or single breath measurements of NO transfer. Nitric Oxide 2006;15:199-208.