Clinical Significance of Elevated Diffusing Capacity

Chest

Volumn 125, Issue 2, 2004, Pages 446-452

  Saydain, Ghulam ^a   Beck, Kenneth C ^b   Decker, Paul A ^c   Cowl, Clayton T ^c   Scanlon, Paul D ^c  

^a NASSAU UNIVERSITY MEDICAL CENTER   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c MAYO CLINIC COLLEGE OF MEDICINE   (United States)

Author keywords

Asthma; Diffusing capacity; Obesity; Pulmonary function test

Indexed keywords

CARBON MONOXIDE;

ADULT; AGED; AIRWAY OBSTRUCTION; ARTICLE; ASTHMA; BLOOD GAS ANALYSIS; BODY MASS; BODY SURFACE; BODY WEIGHT; CASE CONTROL STUDY; COMPARATIVE STUDY; CONTROLLED STUDY; CORRELATION ANALYSIS; DATA BASE; DEMOGRAPHY; DIAGNOSTIC PROCEDURE; FEMALE; HEART LEFT RIGHT SHUNT; HEMOPTYSIS; HUMAN; LABORATORY; LUNG ALVEOLUS; LUNG DIFFUSION CAPACITY; LUNG FUNCTION TEST; MAJOR CLINICAL STUDY; MALE; MEDICAL PRACTICE; OBESITY; POLYCYTHEMIA; PREDICTION; PREDICTION AND FORECASTING; PRIORITY JOURNAL; PROBABILITY; PROGNOSIS; PROSPECTIVE STUDY; REFERENCE VALUE; SENSITIVITY AND SPECIFICITY; TOTAL LUNG CAPACITY;

EID: 1242329149     PISSN: 00123692     EISSN: None     Source Type: Journal    
DOI: 10.1378/chest.125.2.446     Document Type: Article

References (23)

1. American Thoracic Society. Single breath carbon monoxide diffusing capacity (transfer factor): recommendations for a standard technique; 1995 update. Am J Respir Crit Care Med 1995; 152:2185-2198
2. Crapo RO, Jensen RL, Wanger JS. Single-breath carbon monoxide diffusing capacity. Clin Chest Med 2001; 22:637-649
3. Smith TC, Rankin J. Pulmonary diffusing capacity and the capillary bed during Valsalva and Müller maneuvers. J Appl Physiol 1969; 27:826-833
4. Coulter TD, Stoller JK. What causes an elevated diffusing capacity? Respir Care 2000; 45:531-532
5. Collard P, Njinou B, Nejadnik B, et al. Single breath diffusing capacity for carbon monoxide in stable asthma. Chest 1994; 105:1426-1429
6. Weitzman RH, Wilson AF. Diffusing capacity and over-all ventilation: perfusion in asthma. Am J Med 1974; 57:767-774
7. Meisner P, Hugh-Jones P. Pulmonary function in bronchial asthma. BMJ 1968; 1:470-475
8. Ray CS, Sue DY, Bray G, et al. Effects of obesity on respiratory function. Am Rev Respir Dis 1983; 128:501-506
9. Biring MS, Lewis MI, Liu JT, et al. Pulmonary physiologic changes of morbid obesity. Am J Med Sci 1999; 318:293-297
10. Ewan PW, Jones HA, Rhodes CG, et al. Detection of intrapulmonary hemorrhage with carbon monoxide uptake: application in Goodpasture's syndrome. N Engl J Med 1976; 295:1391-1396
11. Rosenbaum PR. Optimal matching for observational studies. J Am Stat Assoc 1989; 84:1024-1032
12. American Thoracic Society. Standardization of spirometry: 1994 update. Am J Respir Crit Care Med 1995; 152:1107-1136
13. American Thoracic Society. Lung function testing: selection of reference values and interpretive strategies. Am Rev Respir Dis 1991; 144:1202-1218
14. Miller A, Thornton JC, Warshaw R, et al. Single breath diffusing capacity in a representative sample of the population of Michigan, a large industrial state. Am Rev Respir Dis 1983; 127:270-277
15. Breslow NE, Day NE. Statistical methods in cancer research (vol 1): the analysis of case-control studies. Washington, DC; IARC Scientific Publications, 1980; 325-338
16. Hourani JM, Bellamy PE, Tashkin DP, et al. Pulmonary dysfunction in advanced liver disease: frequent occurrence of an abnormal diffusing capacity. Am J Med 1991; 90:693-700
17. Stam H, Hrachovina V, Stijuen T, et al. Diffusing capacity dependent on lung volume and age in normal subjects. J Appl Physiol 1994; 76:2356-2363
18. Chin DJ, Cotes JE, Flowers R, et al. Transfer factor (diffusing capacity) standardized for alveolar volume: validation, reference values and application of a new linear model to replace KCO (TL/VA). Eur Respir J 1996; 9:1269-1277
19. Licata G, Scaglione R, Barbagallo M, et al. Effect of obesity on left ventricular function studied by radionuclide angiocardiography. Int J Obes 1991; 15:295-302
20. Karason K, Wallentin I, Larsson B, et al. Effects of obesity and weight loss on cardiac function and valvular performance. Obes Res 1998; 6:422-429
21. Collard P, Wilpurte J, Aubert G, et al. The single breath diffusing capacity for carbon monoxide in obstructive sleep apnea and obesity. Chest 1996; 110:1189-1193
22. Baylor P, Goebel P. Clinical correlates of an elevated diffusing capacity for carbon monoxide corrected for alveolar volume. Am J Med Sci 1996; 311:266-271
23. Graham B, Mink JT, Cotton DJ. Overestimation of the single breath carbon monoxide diffusing capacity in patients with air-flow obstruction. Am Rev Respir Dis 1984; 129:403-408