Ventilatory and perceptual responses to cycle exercise in obese women

Journal of Applied Physiology

Volumn 102, Issue 6, 2007, Pages 2217-2226

  Ofir, Dror ^a   Laveneziana, Pierantonio ^a   Webb, Katherine A ^a   O'Donnell, Denis E ^a,b  

^a QUEEN S UNIVERSITY   (Canada)

^b NONE   (Canada)

Author keywords

Dynamic hyperinflation; Expiratory flow limitation; Neuromechanical coupling; Obesity; Respiratory mechanics

Indexed keywords

OXYGEN;

ADULT; AGED; ARTICLE; BODY MASS; CLINICAL ARTICLE; CONTROLLED STUDY; COST EFFECTIVENESS ANALYSIS; DYSPNEA; EXERCISE; EXPIRATORY FLOW RATE; EXPIRATORY RESERVE VOLUME; FEMALE; HUMAN; INSPIRATORY CAPACITY; LOCOMOTION; LUNG VENTILATION; METABOLIC REGULATION; OBESITY; OXYGEN CONSUMPTION; PRIORITY JOURNAL;

ADULT; AGED; AGED, 80 AND OVER; DYSPNEA; EXERCISE TEST; EXERTION; FEMALE; HUMANS; MIDDLE AGED; MODELS, BIOLOGICAL; OBESITY; OXYGEN; OXYGEN CONSUMPTION; RESPIRATORY MECHANICS;

EID: 34447520435     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.00898.2006     Document Type: Article

References (58)

1. Aaron EA, Johnson BD, Seow KC, Dempsey JA. Oxygen cost of exercise hyperpnea: implication for performance. J Appl Physiol 72: 1818-1825, 1992.
2. American Thoracic Society. Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 152: S77-S120, 1995.
3. American Thoracic Society; American College of Chest Physicians. ATS/ACCP Statement on cardiopulmonary exercise testing. Am J Respir Crit Care Med 167: 211-277, 2003.
4. American Thoracic Society/European Respiratory Society. ATS/ERS Statement on respiratory muscle testing. Am J Respir Crit Care Med 166: 518-624, 2002.
5. Babb TG, Buskirk ER, Hodgson JL. Exercise end-expiratory lung volumes in lean and moderately obese women. Int J Obes 13: 11-19, 1989.
6. Babb TG, DeLorey DS, Wyrick BL, Gardner PP. Mild obesity does not limit change in end-expiratory lung volume during cycling in young women. J Appl Physiol 92: 2483-2490, 2002.
7. Babb TG, Korzick D, Meador M, Hodgson JL, Buskirk ER. Ventilatory response of moderately obese women to submaximal exercise. Int J Obes 15: 59-65, 1991.
8. Black LF, Hyatt RE. Maximal respiratory pressures: normal values, and relationship to age and sex. Am Rev Respir Dis 99: 696-702, 1969.
9. Borg GAV. Psychophysical basis of perceived exertion. Med Sci Sports Exerc 14: 377-381, 1982.
10. Briscoe WA, Dubois AG. The relationship between airway resistance, airway conductance, and lung volumes in subjects of different age and body size. J Clin Invest 37: 1279-1285, 1959.
11. Burrows B, Kasik JE, Niden AH, Barclay WR. Clinical usefulness of the single-breath pulmonary diffusing capacity test. Am Rev Respir Dis 84: 789-806, 1961.
12. Chen Z, Eldridge FL, Wagner PG. Respiratory-associated thalamic activity is related to level of respiratory drive. Respir Physiol 90: 99-113, 1992.
13. Chonan T, Mulholland MB, Cherniack NS, Altose MD. Effects of voluntary constraining of thoracic displacement during hypercapnia. J Appl Physiol 63: 1822-1828, 1987.
14. Collins LC, Hoberty PD, Walker JF, Fletcher EC, Peiris AN. The effect of body fat distribution on pulmonary function tests. Chest 107: 1298-1302, 1995.
15. Crapo RO, Morris AH, Clayton PD, Nixon CR. Lung volumes in healthy nonsmoking adults. Bull Eur Physiopathol Respir 18: 419-425, 1982.
16. Davenport PW, Friedman WA, Thompson FJ, Franzen O. Respiratoryrelated cortical potentials evoked by inspiratory occlusion in humans. J Appl Physiol 60: 1843-1848, 1986.
17. Davis JA, Whipp BJ, Wasserman K. The relation of ventilation to metabolic rate during moderate exercise in man. Eur J Appl Physiol 44: 97-108, 1980.
18. Expert Panel on the Identification, Evaluation, and Treatment of Overweight in Adults. Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults: executive summary. Am J Clin Nutr 68: 899-917, 1998.
19. Ferretti A, Giampicolo P, Cavalli A, Milic-Emili J, Tantucci C. Expiratory flow limitation and orthopnea in massively obese subjects. Chest 119: 1401-1408, 2001.
20. Gandevia SC. The perception of motor commands on effort during muscular paralysis. Brain 105: 151-195, 1982.
21. Gandevia SC, Macefield G. Projection of low threshold afferents from human intercostals muscles to the cerebral cortex. Respir Physiol 77: 203-214, 1989.
22. Hamilton AL, Killian KJ, Summers E, Jones NL. Muscle strength, symptom intensity, and exercise capacity in patients with cardiorespiratory disorders. Am J Respir Crit Care Med 152: 2021-2031, 1995.
23. Harty HR, Corfield DR, Schwartzstein RM, Adams L. External thoracic restriction, respiratory sensation and ventilation during exercise in men. J Appl Physiol 86: 1142-1150, 1999.
24. Henke KG, Sharratt M, Pegelow D, Dempsey JA. Regulation of end-expiratory lung volume during exercise. J Appl Physiol 64: 135-146, 1988.
25. Hernandez P, Maltais F, Gursahaney A, LeBlanc P, Gottfried SB. Proportional assist ventilation may improve exercise performance in severe chronic obstructive pulmonary disease. J Cardiopulm Rehabil 21: 135-142, 2001.
26. Johnson BD, Reddan WG, Pegelow DF, Seow KC, Dempsey JA. Flow limitation and regulation of functional residual capacity during exercise in a physically active aging population. Am Rev Respir Dis 143: 960-967, 1991.
27. Johnson BD, Saupe KW, Dempsey JA. Mechanical constraints on exercise hyperpnea in endurance athletes. J Appl Physiol 77: 963-973, 1992.
28. Johnson BD, Weisman IM, Zeballos RJ, Beck KC. Emerging concepts in the evaluation of ventilatory limitation during exercise: the exercise tidal flow-volume loop. Chest 116: 488-503, 1999.
29. Jones NJ. Clinical Exercise Testing (3rd ed.). Philadelphia, PA: Saunders, 1988.
30. Killian KJ, Summers E, Jones NL, Campbell EJ. Dyspnea and leg effort during incremental cycle ergometry. Am Rev Respir Dis 145: 1339-1345, 1992.
31. Lazarus R, Sparrow D, Weiss ST. Effect of obesity and fat distribution on ventilatory function: the normative aging study. Chest 111: 891-898, 1997.
32. Macintyre N, Crapo RO, Viegi G, Johnson DC, van der Grinten CP, Brusasco V, Burgos F, Casaburi R, Coates A, Enright P, Gustafsson P, Hankinson J, Jensen R, McKay R, Miller MR, Navajas D, Pedersen OF, Pellegrino R, Wanger J; on behalf of the ATS/ERS Task Force. Standardisation of the single-breath determination of carbon monoxide uptake in the lung. Eur Respir J 26: 720-735, 2005.
33. Mahler DA, Weinberg DH, Wells CK, Feinstein AR. The measurement of dyspnea: contents, interobserver agreement, and physiologic correlates of two new clinical indexes. Chest 85: 751-758, 1984.
34. Matthews PBC. Where does Sherrington's 'muscular sense' originate: muscles, joints, corollary discharge? Annu Rev Neurosci 5: 189-218, 1982.
35. McGavin CR, Artvinli M, Naoe H, McHardy GJ. Dyspnoea, disability, and distance walked: comparison of estimates of exercise performance in respiratory disease. Br Med J 2: 241-243, 1978.
36. Miller MR, Crapo R, Hankinson J, Brusasco V, Burgos F, Casaburi R, Coates A, Enright P, van der Grinten CP, Gustafsson P, Jensen R, Johnson DC, MacIntyre N, McKay R, Navajas D, Pedersen OF, Pellegrino R, Viegi G, Wanger J; on behalf of the ATS/ERS Task Force. General considerations for lung function testing. Eur Respir J 26: 153-161, 2005.
37. Miller MR, Hankinson J, Brusasco V, Burgos F, Casaburi R, Coates A, Crapo R, Enright P, van der Grinten CP, Gustafsson P, Jensen R, Johnson DC, MacIntyre N, McKay R, Navajas D, Pedersen OF, Pellegrino R, Viegi G, Wanger J; on behalf of the ATS/ERS Task Force. Standardisation of spirometry. Eur Respir J 26: 319-338, 2005.
38. Moosavi SH, Topulos GP, Hafer A, Lansing RW, Adams L, Brown R, Banzett RB. Acute partial paralysis alters perceptions of air hunger, work and effort at constant PCO2 and V? E. Respir Physiol 122: 45-60, 2000.
39. Morris JF, Koski A, Temple WP, Claremont A, Thomas DR. Fifteenyear interval spirometric evaluation of the Oregon predictive equations. Chest 92: 123-127, 1988.
40. Naimark A, Cherniack RM. Compliance of the respiratory system and its components in health and obesity. J Appl Physiol 15: 377-382, 1960.
41. O'Donnell D, Flüge T, Gerken F, Hamilton A, Webb K, Aguilaniu B, Make B, Magnussen H. Effects of tiotropium on lung hyperinflation, dyspnoea and exercise tolerance in COPD. Eur Respir J 23: 832-840, 2004.
42. O'Donnell DE, Hamilton AL, Webb KA. Sensory-mechanical relationships during high-intensity, constant-work-rate exercise in COPD. J Appl Physiol 101: 1025-1035, 2006.
43. O'Donnell DE, Hong HH, Webb KA. Respiratory sensation during chest wall restriction and dead space loading in exercising men. J Appl Physiol 88: 1859-1869, 2000.
44. O'Donnell DE, Lam M, Webb KA. Measurement of symptoms, lung hyperinflation and endurance during exercise in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 158: 1557-1565, 1998.
45. O'Donnell DE, Revill SM, Webb KA. Dynamic hyperinflation and exercise intolerance in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 164: 770-777, 2001.
46. O'Donnell DE, Sanii R, Giesbrecht G, Younes M. Effect of continuous positive airway pressure on respiratory sensation in patients with chronic obstructive pulmonary disease during submaximal exercise. Am Rev Respir Dis 138: 1185-1191, 1988.
47. Pellegrino R, Viegi G, Brusasco V, Crapo RO, Burgos F, Casaburi R, Coates A, van der Grinten CP, Gustafsson P, Hankinson J, Jensen R, Johnson DC, MacIntyre N, McKay R, Miller MR, Navajas D, Pedersen OF, Wanger J; on behalf of the ATS/ERS Task Force. Interpretative strategies for lung function tests. Eur Respir J 26: 948-968, 2005.
48. Peters MM, Webb KA, O'Donnell DE. Combined physiological effects of bronchodilators and hyperoxia on exertional dyspnea in normoxic COPD. Thorax 61: 559-567, 2006.
49. Powell BD, Redfield MM, Bybee KA, Freeman WK, Rihal CS. Association of obesity with left ventricular remodeling and diastolic dysfunction in patients without coronary artery disease. Am J Cardiol 98: 116-120, 2006.
50. Rubinstein I, Zamel N, DuBarry L, Hoffstein V. Airflow limitation in morbidly obese, nonsmoking men. Ann Intern Med 112: 828-832, 1990.
51. Sharp JT, Henry JP, Sweany SK, Meadows WR, Pietras RJ. The total work of breathing in normal and obese men. J Clin Invest 43: 728-739, 1964.
52. Simon PM, Schwartzstein RM, Weiss JW, Fencl V, Teghtsoonian M, Weinberger SE. Distinguishable types of dyspnea in patients with shortness of breath. Am Rev Respir Dis 142: 1009-1014, 1990.
53. Stubbing DG, Pengelly LD, Morse JLC, Jones NL. Pulmonary mechanics during exercise in normal males. J Appl Physiol 49: 506-510, 1980.
54. Wanger J, Clausen JL, Coates A, Pedersen OF, Brusasco V, Burgos F, Casaburi R, Crapo R, Enright P, van der Grinten CP, Gustafsson P, Hankinson J, Jensen R, Johnson D, Macintyre N, McKay R, Miller MR, Navajas D, Pellegrino R, Viegi G; on behalf of the ATS/ERS Task Force. Standardisation of the measurement of lung volumes. Eur Respir J 26: 511-522, 2005.
55. Wasserman K, Hansen JE, Sue DY, Casaburi R, Whipp BJ. Principles of Exercise Testing and Interpretation (3rd ed.) Baltimore, MD: Lippincott Williams & Wilkins, 1999.
56. Xu F, Taylor RF, McLarney T, Lee LY, Frazier DT. Respiratory load compensation. 1. Role of the cerebrum. J Appl Physiol 74: 853-858, 1993.
57. Yan S, Kaminski D, Sliwinski P. Reliability of inspiratory capacity for estimating end expiratory lung volume changes during exercise in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 156: 55-59, 1997.
58. Zerah F, Harf A, Perlemuter L, Lorino H, Lorino AM, Atlan G. Effects of obesity on respiratory resistance. Chest 103: 1470-1476, 1993.