Effects of sepsis on neonatal thrombopoiesis

Pediatric Research

Volumn 64, Issue 4, 2008, Pages 399-404

  Brown, Rachel E ^a,d   Rimsza, Lisa M ^c   Pastos, Karen ^a   Young, Linda ^b   Saxonhouse, Matthew A ^a   Bailey, Matthew ^a   Lawrence, Robert M ^a   Sola Visner, Martha C ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b University of Arizona ^*  (United States)

^c UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^d NATIONWIDE CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

THROMBOPOIETIN;

ARTICLE; CLINICAL ARTICLE; FEMALE; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; HUMAN; MALE; MEGAKARYOCYTE; NECROTIZING ENTEROCOLITIS; NEWBORN; PRIORITY JOURNAL; RETICULATED PLATELET; SEPSIS; THROMBOCYTE; THROMBOCYTE RELEASE REACTION; THROMBOCYTOPENIA; THROMBOCYTOPOIESIS; UPREGULATION;

ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FLORIDA; GESTATIONAL AGE; HUMANS; INFANT, NEWBORN; MALE; PLATELET COUNT; SEPSIS; THROMBOPOIESIS; THROMBOPOIETIN;

EID: 55049132571     PISSN: 00313998     EISSN: None     Source Type: Journal    
DOI: 10.1203/PDR.0b013e318181ad49     Document Type: Article

References (43)

1. Mehta P, Vasa R, Neumann L, Karpatkin M 1980 Thrombocytopenia in the high-risk infant. J Pediatr 97:791-794
2. Castle V, Andrew M, Kelton J, Giron D, Johnston M, Carter C 1986 Frequency and mechanism of neonatal thrombocytopenia. J Pediatr 108:749-755
3. Christensen RD, Henry E, Wiedmeier SE, Stoddard RA, Sola-Visner MC, Lambert DK, Kiehn TI, Ainsworth S 2006 Thrombocytopenia among extremely low birth weight neonates: data from a multihospital healthcare system. J Perinatal 26:348-353
4. Andrew M, Castle V, Saigal S, Carter C, Kelton JG 1987 Clinical impact of neonatal thrombocytopenia. J Pediatr 110:457-464
5. Tsimberidou AM, Giles FJ, Khouri I, Bueso-Ramos C, Pilat S, Thomas DA, Cortes J, Kurzrock R 2005 Low-dose interleukin-11 in patients with bone marrow failure: update of the M. D. Anderson Cancer Center experience. Ann Oncol 16:139-145
6. Bussel JB, Kuter DJ, George JN, McMillan R, Aledort LM, Conklin GT, Lichtin AE, Lyons RM, Nieva J, Wasser JS, Wiznitzer I, Kelly R, Chen CF, Nichol JL 2006 AMG 531, a thrombopoiesis-stimulating protein, for chronic ITP. N Engl J Med 355:1672-1681
7. Colarizi P, Fiorucci P, Caradonna A, Ficuccilli F, Mancuso M, Papoff P 1999 Circulating thrombopoietin levels in neonates with infection. Acta Paediatr 88:332-337
8. Oygur N, Tunga M, Mumcu Y, Yesilipek A, Gura A, Coskun M, Yegin O 2001 Thrombopoietin levels of thrombocytopenic term and preterm newborns with infection. Am J Perinatal 18:279-286
9. Fielder PJ, Gumey AL, Stefanich E, Marian M, Moore MW, Carver-Moore K, de Sauvage FJ 1996 Regulation of thrombopoietin levels by c-mpl-mediated binding to platelets. Blood 87:2154-2161
10. Emmons RV, Reid DM, Cohen RL, Meng G, Young NS, Dunbar CE, Shulman NR 1996 Human thrombopoietin levels are high when thrombocytopenia is due to megakaryocyte deficiency and low when due to increased platelet destruction. Blood 87:4068-4071
11. Ishiguro A, Suzuki Y, Mito M, Shimbo T, Matsubara K, Kato T, Miyazaki H 2002 Elevation of serum thrombopoietin precedes thrombocytosis in acute infections. Br J Haematol 116:612-618
12. Wolber EM, Fandrey J, Frackowski U, Jelkmann W 2001 Hepatic thrombopoietin mRNA is increased in acute inflammation. Thromb Haemost 86:1421-1424
13. Wolber EM, Jelkmann W 2000 Interleukin-6 increases thrombopoietin production in human hepatoma cells HepG2 and Hep3B. J Interferon Cytokine Res 20:499-506
14. Kaushansky K 2005 The molecular mechanisms that control thrombopoiesis. J Clin Invest 115:3339-3347
15. Kaushansky K 2006 Lineage-specific hematopoietic growth factors. N Engl J Med 354:2034-2045
16. Saxonhouse MA, Christensen RD, Walker DM, Hutson AD, Sola MC 2004 The concentration of circulating megakaryocyte progenitors in preterm neonates is a function of post-conceptional age. Early Hum Dev 78:119-124
17. Saxonhouse MA, Sola MC, Pastos KM, Ignatz ME, Hutson AD, Christensen RD, Rimsza LM 2004 Reticulated platelet percentages in term and preterm neonates. J Pediatr Hematol Oncol 26:797-802
18. Sola MC, Calhoun DA, Hutson AD, Christensen RD 1999 Plasma thrombopoietin concentrations in thrombocytopenic and non-thrombocytopenic patients in a neonatal intensive care unit. Br J Haematol 104:90-92
19. Kaushansky K, Broudy VC, Lin N, Jorgensen MJ, McCarty J, Fox N, Zucker-Franklin D, Lofton-Day C 1995 Thrombopoietin, the Mp1 ligand, is essential for full megakaryocyte development. Proc Natl Acad Sci USA 92:3234-3238
20. Murray NA, Watts TL, Roberts IA 1998 Endogenous thrombopoietin levels and effect of recombinant human thrombopoietin on megakaryocyte precursors in term and preterm babies. Pediatr Res 43:148-151
21. Sola MC, Du Y, Hutson AD, Christensen RD 2000 Dose-response relationship of megakaryocyte progenitors from the bone marrow of thrombocytopenic and non-thrombocytopenic neonates to recombinant thrombopoietin. Br J Haematol 110:449-453
22. Murray NA, Roberts IA 1995 Circulating megakaryocytes and their progenitors (BFU-MK and CFU-MK) in term and pre-term neonates. Br J Haematol 89:41-46
23. Murray NA, Roberts IA 1996 Circulating megakaryocytes and their progenitors in early thrombocytopenia in preterm neonates. Pediatr Res 40:112-119
24. Ault KA, Knowles C 1995 In vivo biotinylation demonstrates that reticulated platelets are the youngest platelets in circulation. Exp Hematol 23:996-1001
25. Peterec SM, Brennan SA, Rinder HM, Wnek JL, Beardsley DS 1996 Reticulated platelet values in normal and thrombocytopenic neonates. J Pediatr 129:269-274
26. Fabris F, Cordiano I, Steffan A, Ramon R, Scandellari R, Nichol JL, Girolami A 2000 Indirect study of thrombopoiesis (TPO, reticulated platelets, glycocalicin) in patients with hereditary macrothrombocytopenia. Eur J Haematol 64:151-156
27. Kurata Y, Hayashi S, Kiyoi T, Kosugi S, Kashiwagi H, Honda S, Tomiyama Y 2001 Diagnostic value of tests for reticulated platelets, plasma glycocalicin, and thrombopoietin levels for discriminating between hyperdestructive and hypoplastic thrombocytopenia. Am J Clin Pathol 115:656-664
28. Zakynthinos SG, Papanikolaou S, Theodoridis T, Zakynthinos EG, ChristopoulouKokkinou V, Katsaris G, Mavrommatis AC 2004 Sepsis severity is the major determinant of circulating thrombopoietin levels in septic patients. Crit Care Med 32:1004-1010
29. Watts TL, Murray NA, Roberts IA 1999 Thrombopoietin has a primary role in the regulation of platelet production in preterm babies. Pediatr Res 46:28-32
30. Bjerre A, Ovstebo R, Kierulf P, Halvorsen S, Brandtzaeg P 2000 Fulminant meningococcal septicemia: dissociation between plasma thrombopoietin levels and platelet counts. Clin Infect Dis 30:643-647
31. Hiyoyama K, Wada H, Shimura M, Nakasaki T, Katayama N, Nishikawa M, Shiku H, Tahara T, Kato T 1997 Increased serum levels of thrombopoietin in patients with thrombotic thrombocytopenic purpura, idiopathic thrombocytopenic purpura, or disseminated intravascular coagulation. Blood Coagul Fibrinolysis 8:345-349
32. Sola-Visner MC, Christensen RD, Hutson AD, Rimsza LM 2007 Megakaryocyte size and concentration in the bone marrow of thrombocytopenic and nonthrombocytopenic neonates. Pediatr Res 61:479-484
33. Lambert MP, Rauova L, Bailey M, Sola-Visner MC, Kowalska MA, Poncz M 2007 Platelet factor 4 is a negative autocrine in vivo regulator of megakaryopoiesis: clinical and therapeutic implications. Blood 110:1153-1160
34. Stohlawetz P, Folman CC, von dem Borne AE, Pernerstorfer T, Eichler HG, Panzer S, Jilma B 1999 Effects of endotoxemia on thrombopoiesis in men. Thromb Haemost 81:613-617
35. Harker LA, Finch CA 1969 Thrombokinetics in man. J Clin Invest 48:963-974
36. Peck-Radosavljevic M, Wichlas M, Zacherl J, Stiegler G, Stohlawetz P, Fuchsjager M, Kreil A, Metz-Schimmerl S, Panzer S, Steininger R, Muhlbacher F, Ferenci P, Pidlich J, Gangl A 2000 Thrombopoietin induces rapid resolution of thrombocytopenia after orthotopic liver transplantation through increased platelet production. Blood 95:795-801
37. Panasiuk A, Prokopowicz D, Zak J, Panasiuk B 2004 Reticulated platelets as a marker of megakaryopoiesis in liver cirrhosis; relation to thrombopoietin and hepatocyte growth factor serum concentration. Hepatogastroenterology 51:1124-1128
38. Li J, Yang C, Xia Y, Bertino A, Glaspy J, Roberts M, Kuter DJ 2001 Thrombocytopenia caused by the development of antibodies to thrombopoietin. Blood 98:3241-3248
39. Savoia A, Dufour C, Locatelli F, Noris P, Ambaglio C, Rosti V, Zecca M, Ferrari S, di Bari F, Corcione A, Di Stazio M, Seri M, Balduini CL 2007 Congenital amegakaryoevtic thrombocytopenia: clinical and biological consequences of five novel mutations. Haematologica 92:1186-1193
40. Colarizi P, Fiorucci P, Roggini M, Papoff P 1999 Circulating thrombopoietin levels in a neonate with osteopetrosis. Pediatrics 103:700-701
41. Marsh JC, Gibson FM, Prue RL, Bowen A, Dunn VT, Hornkohl AC, Nichol JL, Gordon-Smith EC 1996 Serum thrombopoietin levels in patients with aplastic anaemia. Br J Haematol 95:605-610
42. Cole JL, Marzec UM, Gunthel CJ, Karpatkin S, Worford L, Sundell IB, Lennox JL, Nichol JL, Harker LA 1998 Ineffective platelet production in thrombocytopenic human immunodeficiency virus-infected patients. Blood 91:3239-3246
43. Tighe P, Rimsza LM, Christensen RD, Lew J, Sola MC 2005 Severe thrombocytopenia in a neonate with congenital HIV infection. J Pediatr 146:408-413