Amelioration of skewed Th1/Th2 balance in tumor-bearing and asthma-induced mice by oral administration of Agaricus blazei extracts

Immunopharmacology and Immunotoxicology

Volumn 30, Issue 4, 2008, Pages 747-760

  Takimoto, Hiroaki ^a   Kato, Hanano ^a   Kaneko, Masahiro ^a   Kumazawa, Yoshio ^a  

^a KITASATO UNIVERSITY   (Japan)

Author keywords

Agaricus; Anti tumor; Asthma; Eosinophils; IgE; Th1 Th2

Indexed keywords

AGARICUS BLAZEI EXTRACT; ALPHA4 INTEGRIN; CHLORDANE; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A; INTERLEUKIN 4; INTERLEUKIN 5; MONOCLONAL ANTIBODY CD3;

AGARICUS BLAZEI; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; ARTICLE; ASTHMA; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; IMMUNOMODULATION; INTERFERON PRODUCTION; LUNG LAVAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPLEEN CELL; T LYMPHOCYTE ACTIVATION; TH1 CELL; TH2 CELL; TUMOR IMMUNOLOGY; TUMOR XENOGRAFT;

ADMINISTRATION, ORAL; AGARICUS; ANIMALS; ANTI-ASTHMATIC AGENTS; ANTIGENS, NEOPLASM; ANTINEOPLASTIC AGENTS; ASTHMA; FEMALE; FIBROSARCOMA; HISTOCOMPATIBILITY ANTIGENS; IMMUNITY, CELLULAR; MICE; MICE, INBRED BALB C; TH1 CELLS; TH2 CELLS;

AGARICUS; AGARICUS BLAZEI; MUS;

EID: 54949107003     PISSN: 08923973     EISSN: 15322513     Source Type: Journal    
DOI: 10.1080/08923970802279092     Document Type: Article

References (32)

1. Blay, J.-Y.; Burdin, N.; Rousset, F.; Lenoir, G.; Biron, P.; Philip, T. Serum interleukin-10 in non-Hodgkin's lymphoma: A prognostic factor. Blood 1993, 82 (7), 2169-2174.
2. Smith, D.R.; Kunkel, S.L.; Burdick, M.D.; Wilke, C.A.; Orringer, M.B.; Wliyter, I.; Strieter, R.M. Production of interleukin-10 by human bronchogenic carcinoma. Am. J. Pathol. 1994, 145 (1), 18-25.
3. + T cells in peripheral blood of colorectal cancer patients and involvement in cancer establishment and progression. Cancer Immunol. Immunother. 1996, 42 (1), 1-8.
4. O'Hara, R.J.; Greenman, J.; MacDonald, A.W.; Gaskell, K.M.; Topping, K.P.; Duthie, G.S.; Kerin, M.J.; Lee, P.W.; Monson, J.R. Advanced colorectal cancer is associated with impaired interleukin 12 and enhanced interleukin 10 production. Clin. Cancer Res. 1998, 4 (8), 1943-1948.
5. De Vita, F.; Orditura, M.; Galizia, G.; Romano, C.; Lieto, E.; Iodice, P.; Tuccillo, C.; Catalano, G, Serum interleukin-10 is an independent prognostic factor in advanced solid tumors. Oncol. Rep. 2000, 7 (2), 357-361.
6. Takimoto, H.; Wakita, D.; Kawaguchi, K.; Kumazawa, Y. Potentiation of cytotoxic activity in naïve and tumor-bearing mice by oral administration of hot-water extracts from Agaricus blazei fruiting bodies. Biol. Pharm. Bull. 2004, 27 (3), 404-406.
7. Romagnani, S. Regulation of the development of type-2 T-helper cells in allergy. Curr. Opin. Immunol. 1994, 6 (6), 838-846.
8. Coyle, A.J.; Wagner, K.; Bertrand, C.; Tsuyuki, S.; Bews, J.; Heusser, C. Central role of immunoglobulin (Ig) E in the induction of lung eosinophil infiltration and T helper 2 cell cytokine production: Inhibition by a non-anaphylactogenic anti-IgE antibody. J. Exp. Med. 1996, 183 (4), 1303-1310.
9. Ray, A.; Cohn, R.S. Th2 cells and GATA-3 in asthma: New insights into the regulation of airway inflammation. J. Clin. Invest. 1999, 104 (8), 985-993.
10. Lambrecht, B.N.; De Veeman, M.; Coyle, A.J.; Gutierrez-Ramos, J.C.; Thielemans, K.; Pauwels, R.A. Myeloid dendtritic cells induce Th2 responses to inhaled antigen, leading to eosinophilic airway inflammation. J. Clin. Invest. 2000, 106 (4), 551-559.
11. Stavnezer, J. Immunoglobulin class switching. Curr. Opin. Immunol. 1996, 8 (2), 199-205.
12. Corry, D.B.; Kheradmand, F. Induction and regulation of the IgE response. Nature 1999, 402 (6760 Suppl.), B18-B23.
13. Bacharier, L.B. Geha, R.S. Molecular mechanisms of IgE regulation. J. Allergy Clin. Immunol. 2000, 105 (2 Pt 2), S547-S558.
14. Maggi, E. The TH1/TH2 paradigm in allergy. Immunotechnol. 1998, 3 (4), 233-244.
15. Randolph, D.A.; Stephens, R.; Curruthers, C.J.L.; Chaplin, D.C. Cooperation between Th1 and Th2 cells in a murine model of eosinophilic airway inflammation. J. Clin. Invest. 1999, 104 (8), 1021-1029.
16. Marone, G.; Spadaro, G.; Palumbo, C.; Condorelli, G. The anti-IgE/anti-FcεRIα autoantibody network in allergic and autoimmune diseases. Clin. Exp. Allergy 1999, 29 (1), 17-27.
17. Kovarova, M.; Rivera, J. A molecular understanding of mast cell activation and the promise of anti-allergic therapeutics. Curr. Med. Chem. 2004, 11 (15), 2083-2091.
18. Eum, S.Y.; Maghni, K.; Hamid, Q.; Campbell, H.; Eidelman, D.H.; Martin, J.G. Involvement of the cysteinyl-leukotrienes in allergen-induced airway eosinophilia and hypersensitiveness in the mouse. Am. J. Respir. Cell Mol. Biol. 2003; 28 (1), 25-32.
19. Ryll, R.; Watanabe, K.; Fujiwara, N.; Takimoto, H.; Hasunuma, R.; Kumazawa, Y.; Okada, M.; Yano, I. Mycobacterial cord factor, but not sulfolipid, causes depletion of NKT cells and upregulation of CD11D1 on murine macrophages. Microbes Infect. 2001, 3 (8), 611-619.
20. Luster, A.D.; Ravetch, J.V. Genomic characterization of a γ-interferon-inducing gene (IP-10) and identification of an interferon-inducible hypersensitive site. Mol. Cell. Biol. 1987, 7 (10), 3723-3731.
21. Farber, J.M. Mig and IP-10: CXC chemokines that target lymphocytes. J. Leukocyte Biol. 1997, 61 (3), 246-257.
22. Gauchat, J.F.; Henchoz, S.; Mazzei, G.; Auby, J.P.; Brunner, T.; Blasey, H.; Life, P.; Talabot, D.; Flores Romo, L.; Thompson, J. Induction of human IgE synthesis in B cells by mast cells and basophils. Nature 1993, 365 (6444), 340-343.
23. Gauchat, J.F.; Henchoz, S.; Fattah, D.; Mazzei, G.; Aubry, J.P.; Jomotte, T.; Dash, L.; Page, K.; Solari, R.; Aldebert, D. CD40 ligand is functionally expressed on human eosinophils. Eur. J. Immunol. 1995, 25 (3), 863-865.
24. Burd, P.R.; Thompson, W.C.; Max, E.E.; Mills, F.C. Activated mast cells produce interleukin 13. J. Exp. Med. 1995, 181 (4), 1373-1380.
25. Bendelac, A.; Rivera, M.N.; Park, S.H.; Roark, J.H. Mouse CD1-specific NK1 T cells: development, specificity, and function. Annu. Rev. Immunol. 1997, 15, 535-562.
26. Schwartz, L.B. Tryptase, a mediator of human mast cells. J. Allergy Clin. Immunol. 1990, 86 (4 Pt 2), 594-598.
27. Nadel, J.A. Role of mast cell and neutrophils proteases in airway secretion. Am. Rev. Respir. Dis. 1991, 144 (3 Pt 2), S48-51.
28. Austen, K.F. The Paul Kallos Memorial Lecture. From slow-reacting substance of anaphylaxis to leukotriene C4 synthesis. Int. Arch. Allergy Immunol. 1995, 107 (1-3), 19-24.
29. Bingham, C.O. III; Austen, K.F. Mast-cell responses in the development of asthma. J. Allergy Clin. Immunol. 2000, 105 (2 Pt 2), S527-S534.
30. Charlesworth, E.N. The role of basophils and mast cells in acute and late reactions in the skin. Allergy 1997, 52 (34 Suppl), 31-43.
31. Galli, S.J. The Paul Kallos Memorial Lecture. The mast cell: A versatile effector cell for a challenging world. Int. Arch. Allergy Immunol. 1997, 113 (1-3), 14-22.
32. Galli, S.J. Mast cells and basophils. Curr. Opin. Hematol. 2000, 7 (1), 32-39.