Can TGF-β1 and rhBMP-2 act in synergy to transform bone marrow stem cells to discogenic-type cells?

Acta Neurochirurgica

Volumn 150, Issue 10, 2008, Pages 1073-1079

  Kuh, Sung Uk ^a   Zhu, Yerun ^b   Li, Jun ^b   Tsai, Kai Jow ^b   Fei, Qinming ^b   Hutton, William C ^b,c   Yoon, S Tim ^b  

^a Yonsei University College of Medicine   (South Korea)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Emory Spine Center   (United States)

Author keywords

Bone marrow derived cells; Proteoglycan; rhBMP 2; TGF 1

Indexed keywords

AGGRECAN; AGGRECAN ANTIBODY; ANTIBODY; BONE MORPHOGENETIC PROTEIN 2 ANTIBODY; BONE MORPHOGENETIC PROTEIN 7 ANTIBODY; COLLAGEN TYPE 1; COLLAGEN TYPE 2; GLYCOSAMINOGLYCAN POLYSULFATE; MESSENGER RNA; OSTEOGENIC PROTEIN 1; RECOMBINANT BONE MORPHOGENETIC PROTEIN 2; TRANSCRIPTION FACTOR SOX9; TRANSFORMING GROWTH FACTOR BETA1; TYPE 1 COLLAGEN ANTIBODY; TYPE 2 COLLAGEN ANTIBODY; UNCLASSIFIED DRUG; BMP2 PROTEIN, HUMAN; BONE MORPHOGENETIC PROTEIN 2; GLYCOSAMINOGLYCAN; HYBRID PROTEIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; FEMUR; FLUORESCENCE MICROSCOPE; GENE EXPRESSION; HEMATOPOIETIC STEM CELL; ILIAC CREST; IMMUNOFLUORESCENCE; NONHUMAN; PRIORITY JOURNAL; RABBIT; REAL TIME POLYMERASE CHAIN REACTION; STAINING; ANIMAL; BIOSYNTHESIS; BONE MARROW CELL; BONE MARROW TRANSPLANTATION; CELL DIFFERENTIATION; CHONDROGENESIS; CULTURE TECHNIQUE; CYTOLOGY; DRUG EFFECT; DRUG POTENTIATION; GENETICS; INTERVERTEBRAL DISK; INTERVERTEBRAL DISK HERNIA; METABOLISM; METHODOLOGY; PATHOLOGY; PHYSIOLOGY; REGENERATION; STEM CELL;

AGGRECANS; ANIMALS; BONE MARROW CELLS; BONE MARROW TRANSPLANTATION; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 7; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CHONDROGENESIS; COLLAGEN TYPE I; COLLAGEN TYPE II; DRUG SYNERGISM; GLYCOSAMINOGLYCANS; INTERVERTEBRAL DISK; INTERVERTEBRAL DISK DISPLACEMENT; RABBITS; RECOMBINANT FUSION PROTEINS; REGENERATION; RNA, MESSENGER; STEM CELLS; TRANSFORMING GROWTH FACTOR BETA1;

EID: 54849429750     PISSN: 00016268     EISSN: 09420940     Source Type: Journal    
DOI: 10.1007/s00701-008-0029-z     Document Type: Article

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