The Toxoplasma gondii type-II NADH dehydrogenase TgNDH2-I is inhibited by 1-hydroxy-2-alkyl-4(1H)quinolones

Biochimica et Biophysica Acta - Bioenergetics

Volumn 1777, Issue 11, 2008, Pages 1455-1462

  Lin, San San ^a   Kerscher, Stefan ^b   Saleh, Ahmad ^a   Brandt, Ulrich ^b   Groß, Uwe ^a   Bohne, Wolfgang ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b GOETHE UNIVERSITY   (Germany)

Author keywords

1 Hydroxy 2 alkyl 4(1)quinolone; Alternative (type II) NADH dehydrogenase (NDH2); HDQ; Inhibition kinetics; Ping pong mechanism; Toxoplasma gondii

Indexed keywords

QUINOLONE DERIVATIVE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DEHYDROGENASE; TGNDH2 I ENZYME; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; ENZYME KINETICS; ENZYME SUBSTRATE; IC 50; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TOXOPLASMA GONDII; YARROWIA LIPOLYTICA;

ANIMALS; ENZYME INHIBITORS; MICROSCOPY, FLUORESCENCE; NADH DEHYDROGENASE; OPEN READING FRAMES; QUINOLONES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TOXOPLASMA;

TOXOPLASMA GONDII; YARROWIA LIPOLYTICA;

EID: 54849409669     PISSN: 00052728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbabio.2008.08.006     Document Type: Article

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