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Volumn 47, Issue 37, 2008, Pages 6954-6956

Catalysts for the Sonogashira coupling - The crownless again shall be king

Author keywords

Alkynes; Cross coupling; Homogeneous catalysis; Sonogashira coupling; Transition metals

Indexed keywords


EID: 54749130669     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200802270     Document Type: Short Survey
Times cited : (268)

References (41)
  • 16
    • 54749098887 scopus 로고    scopus 로고
    • The terminology of coupling reactions involving sp-hybridized carbon centers is not applied uniformly in the literature. The term Sonogashira coupling or (less often) Sonogashira-Hagihara coupling now includes the various types of C(sp)-C(sp2) and C(sp)-C(sp 3) cross-coupling reactions, regardless of the catalytically active metal used. However, traditionally, the term Sonogashira coupling corresponded exclusively to the Pd/Cu-catalyzed coupling protocol, whereas the related copper-free reaction was termed Heck(-Cassar) coupling. Although the name Stephens-Castro reaction corresponded originally to the stoichiometric use of copper acetylides, reactions catalyzed exclusively by copper are referred to as either Sonogashira reactions or catalytic Stephens-Castro (or just Castro) reactions
    • 3) cross-coupling reactions, regardless of the catalytically active metal used. However, traditionally, the term "Sonogashira coupling" corresponded exclusively to the Pd/Cu-catalyzed coupling protocol, whereas the related copper-free reaction was termed "Heck(-Cassar) coupling". Although the name "Stephens-Castro reaction" corresponded originally to the stoichiometric use of copper acetylides, reactions catalyzed exclusively by copper are referred to as either Sonogashira reactions or catalytic Stephens-Castro (or just Castro) reactions.
  • 41
    • 54749156028 scopus 로고    scopus 로고
    • To be fair: It took more than 30 years of research on Pd catalysts to reach the present levels of efficiency. With Cu and Fe, there is still plenty of room for improvement. Time will tell if the ligands will remain as simple as they are now.
    • To be fair: It took more than 30 years of research on Pd catalysts to reach the present levels of efficiency. With Cu and Fe, there is still plenty of room for improvement. Time will tell if the ligands will remain as simple as they are now.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.